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ORF3_protein

Euk-Vir

Bat_coronavirus_1A

ORF3_protein__YP_001718606__Bat_coronavirus_1A__393767

Identity

Accession:
YP_001718606 ↗
Protein ID:
ORF3_protein
Kingdom:
euk

Quality

77.7 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Pisoniviricetes› Nidovirales› Coronaviridae› Alphacoronavirus› Bat_coronavirus_1A

TaxID: 393767

Cluster

View cluster (89 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 128-199
PDB
Domain cluster: rep: putative_membrane_protein__YP_009408173__Morelia_viridis_nidovirus__2016400__D128-203
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03053.20 best Corona_NS3b 43.8 3.60e-11 100.0% 32.7%
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2c9aA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.62 46.0 4.16e-01 86.1% 57.7%
3b5mA01 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.61 54.0 4.60e-01 100.0% 87.4%
3by9B01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.61 46.0 3.81e-01 81.9% 73.3%
7cayA01 2.30.130.40 Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › LON domain-like 0.60 50.0 4.52e-01 94.4% 74.0%
1zboA01 2.30.130.40 Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › LON domain-like 0.59 48.0 4.19e-01 93.1% 74.3%
2ip2A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 52.0 3.60e-01 100.0% 42.7%
1xrsB01 3.30.30.60 Alpha Beta › 2-Layer Sandwich › Defensin A-like › D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain 0.58 38.0 4.28e-01 80.6% 96.2%
1shyA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.57 49.0 4.44e-01 100.0% 80.4%
2pmzB07 2.40.50.150 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain 0.56 42.0 3.60e-01 81.9% 88.7%
2ynaA02 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.56 49.0 4.65e-01 100.0% 92.0%
4ci2B02 2.30.130.40 Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › LON domain-like 0.56 46.0 3.93e-01 94.4% 64.0%
2e1bA02 3.30.980.10 Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › Threonyl-trna Synthetase; Chain A, domain 2 0.56 49.0 4.11e-01 100.0% 92.2%
5wl1A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 43.0 3.82e-01 84.7% 58.4%
1twfB07 2.40.50.150 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II, Rpb2 subunit, wall domain 0.56 42.0 3.56e-01 81.9% 88.7%
6vbkA01 2.30.130.40 Mainly Beta › Roll › Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 › LON domain-like 0.56 47.0 4.12e-01 95.8% 73.9%
5h5zA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 40.0 3.83e-01 84.7% 63.6%
2vtfA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.55 46.0 3.54e-01 95.8% 53.7%
2bc4A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.55 43.0 3.76e-01 86.1% 56.0%
4f80A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.54 40.0 3.76e-01 86.1% 62.4%
2l8kA00 3.30.1330.220 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Arterivirus nonstructural protein 7 alpha 0.53 46.0 3.84e-01 94.4% 73.2%
3gs9A01 6.20.110.10 Special › Other non-globular › Thrombin, subunit H › 0.53 46.0 4.50e-01 100.0% 100.0%
4hlyA00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 45.0 4.05e-01 98.6% 97.2%
3of6E00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 41.0 3.72e-01 87.5% 62.5%
2ra1A04 2.60.40.1220 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 38.0 3.54e-01 87.5% 58.8%
2rikA03 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.53 39.0 3.69e-01 81.9% 65.2%
4q9cA00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 41.0 3.69e-01 87.5% 61.0%
5a2fA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 42.0 3.62e-01 87.5% 61.6%
4ckbD02 3.20.100.20 Alpha Beta › Alpha-Beta Barrel › mRNA Triphosphatase Cet1; Chain A › 0.51 43.0 3.24e-01 100.0% 57.6%
2x8kA01 2.40.30.200 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.51 42.0 3.86e-01 98.6% 84.8%
2zoeB02 2.60.120.1080 Mainly Beta › Sandwich › Jelly Rolls › 0.50 41.0 3.33e-01 94.4% 61.8%
2yugA00 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.50 37.0 2.96e-01 80.6% 81.9%
6v6aC01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.50 38.0 3.69e-01 83.3% 73.8%
2jiiA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.50 38.0 3.35e-01 81.9% 61.8%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3390626 1.1.8.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Aminomethyltransferase beta-barrel domain 0.71 46.0 4.77e-01 81.9% 69.6%
2898325 271.1.1.2 ↗ beta barrels › GFP-like › GFP-like › GFP-like 0.68 51.0 3.35e-01 80.6% 19.7%
3415634 223.1.1.25 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_9 0.65 49.0 4.17e-01 80.6% 89.6%
5013196 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.62 45.0 4.17e-01 87.5% 58.9%
3859218 304.3.1.0 ↗ a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.62 47.0 3.93e-01 80.6% 51.7%
4487049 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.62 48.0 3.64e-01 100.0% 34.9%
4257535 1.1.5.25 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ 0.62 54.0 4.64e-01 98.6% 63.5%
4031101 1.1.9.0 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain 0.60 50.0 4.22e-01 95.8% 60.8%
4682340 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.59 44.0 3.72e-01 80.6% 90.4%
3304251 221.1.2.5 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif › S4 0.59 44.0 4.13e-01 80.6% 93.3%
4956728 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.59 44.0 3.65e-01 80.6% 90.0%
5014291 3077.1.1.0 ↗ beta sandwiches › Heme-binding protein HmuY-related › Heme-binding protein HmuY-related › Heme-binding protein HmuY-related 0.59 44.0 3.81e-01 84.7% 84.8%
4983682 1.1.5.17 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › DUF447_N 0.58 50.0 4.14e-01 100.0% 80.7%
4033712 1.1.13.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins 0.58 49.0 4.70e-01 97.2% 100.0%
4946076 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.58 43.0 3.64e-01 80.6% 91.2%
3556801 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.58 43.0 3.62e-01 80.6% 89.6%
3622133 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.57 47.0 3.32e-01 94.4% 31.6%
3396197 2003.1.5.100 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DUF938 0.57 51.0 3.65e-01 100.0% 54.3%
5037173 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.57 44.0 4.06e-01 93.1% 63.2%
4995815 1.1.13.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins 0.57 48.0 4.13e-01 100.0% 74.4%
3491434 325.1.7.2 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › RNA_pol_Rpb2_6 0.56 42.0 3.50e-01 80.6% 94.6%
4976162 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.56 42.0 3.59e-01 80.6% 93.3%
3394788 1.1.17.1 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.56 48.0 3.44e-01 100.0% 36.7%
4970832 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.56 42.0 3.52e-01 80.6% 89.6%
4009059 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.56 42.0 3.37e-01 83.3% 71.6%
4171744 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.55 46.0 3.27e-01 94.4% 35.7%
5056905 1.1.7.28 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › HAS-barrel 0.55 44.0 4.15e-01 94.4% 70.0%
4098347 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.55 46.0 2.83e-01 94.4% 17.1%
4081025 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.55 45.0 3.16e-01 94.4% 31.3%
3658804 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.55 45.0 3.92e-01 93.1% 67.0%
1883205 1.1.13.19 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Caud_tail_N 0.55 46.0 4.13e-01 100.0% 92.7%
4615227 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.55 45.0 3.22e-01 94.4% 35.0%
4382946 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.55 45.0 3.30e-01 94.4% 38.6%
3980899 1.1.13.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins 0.54 46.0 4.03e-01 94.4% 82.7%
4482585 206.1.1.11 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.54 40.0 2.62e-01 83.3% 18.4%
4170287 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.54 45.0 3.30e-01 95.8% 38.6%
4637249 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.54 44.0 3.25e-01 94.4% 39.1%
3721508 11.1.1.122 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › GO-like_E_set 0.54 43.0 3.73e-01 86.1% 57.3%
4107632 304.36.1.1 ↗ a+b two layers › Alpha-beta plaits › YajQ-like › YajQ-like › DUF520 0.54 48.0 4.50e-01 100.0% 93.3%
4648999 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.54 45.0 3.23e-01 94.4% 37.3%
3321290 11.1.1.902 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_GEX2_N 0.53 42.0 3.64e-01 86.1% 60.0%
4886283 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.53 43.0 3.14e-01 94.4% 36.6%
4333314 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.53 40.0 4.19e-01 80.6% 98.5%
185291 1.1.13.20 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Prophage_tailD1 0.53 46.0 4.49e-01 100.0% 98.8%
427 2.4.1.7 ↗ beta barrels › OB-fold › MOP-like › MOP-like › OB_MalK 0.53 32.0 3.64e-01 80.6% 82.7%
2755063 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.53 44.0 3.23e-01 94.4% 39.2%
4279308 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.53 43.0 3.19e-01 94.4% 38.6%
4245054 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.53 43.0 3.10e-01 94.4% 34.2%
4430275 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.53 43.0 3.20e-01 94.4% 38.1%
4588052 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.53 43.0 3.07e-01 94.4% 33.2%
3880638 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.53 35.0 3.44e-01 90.3% 61.3%
4169706 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.53 39.0 2.80e-01 81.9% 46.0%
3389361 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.53 43.0 3.97e-01 94.4% 68.4%
184986 1.1.13.4 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Sipho_tail 0.52 45.0 3.81e-01 98.6% 93.5%
4509138 1.1.9.5 ↗ beta barrels › cradle loop barrel › RIFT-related › PUA domain › LON_substr_bdg 0.52 43.0 3.14e-01 94.4% 37.3%
3685973 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 42.0 3.57e-01 90.3% 54.4%
3881901 11.1.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.52 33.0 3.21e-01 81.9% 55.3%
4973504 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.51 45.0 3.50e-01 100.0% 49.1%
3371896 11.1.1.122 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › GO-like_E_set 0.51 40.0 3.45e-01 86.1% 61.3%
5081561 1.1.13.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins 0.51 41.0 4.09e-01 98.6% 95.0%
3552412 11.1.1.97 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › I-set 0.51 38.0 3.53e-01 93.1% 61.0%
3407835 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.51 44.0 3.07e-01 100.0% 40.5%
3972102 1.1.13.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins 0.50 42.0 3.85e-01 94.4% 77.0%
None — 0.50 40.0 2.51e-01 93.1% 16.9%
3720023 1.1.7.0 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.50 40.0 3.71e-01 94.4% 72.0%
3830759 11.1.1.122 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › GO-like_E_set 0.50 40.0 3.48e-01 87.5% 59.1%
D2 medium residues 3-124
PDB
Domain cluster: rep: ORF3__YP_009380522__Coronavirus_AcCoV-JC34__1964806__D10-119
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03053.20 best Corona_NS3b 111.8 6.00e-32 100.0% 53.5%