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ORF3_protein

Euk-Vir

Bat_coronavirus

ORF3_protein__YP_009824991__Bat_coronavirus__1508220

Identity

Accession:
YP_009824991 ↗
Protein ID:
ORF3_protein
Kingdom:
euk

Quality

66.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 141-216
PDB
CATH (33)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2oolA01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.65 46.0 4.16e-01 75.0% 84.1%
2veaA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.64 45.0 3.83e-01 75.0% 66.2%
4s21B02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.64 45.0 3.91e-01 75.0% 64.7%
2w5eA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.63 45.0 4.79e-01 100.0% 89.2%
2jwpA00 2.60.120.430 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding lectin 0.62 52.0 4.02e-01 94.7% 44.3%
6baoA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.61 43.0 3.56e-01 75.0% 65.7%
1mbmA01 2.40.10.10 Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases 0.61 44.0 4.43e-01 100.0% 77.6%
3hr6A02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.59 52.0 4.10e-01 98.7% 56.1%
4hh2B03 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.59 41.0 3.84e-01 75.0% 95.0%
3nhqA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.59 41.0 3.63e-01 75.0% 73.1%
5iroD00 2.60.40.3530 Mainly Beta › Sandwich › Immunoglobulin-like › 0.58 40.0 3.67e-01 72.4% 82.4%
1d1jB00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.58 40.0 3.45e-01 75.0% 72.8%
3c8cB01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.57 40.0 3.43e-01 75.0% 52.0%
4kqdB00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.56 40.0 3.52e-01 75.0% 79.3%
7alkA01 2.60.40.3510 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 46.0 3.64e-01 90.8% 75.0%
4q63A00 2.40.10.430 Mainly Beta › Beta Barrel › Thrombin, subunit H › 0.56 46.0 4.31e-01 100.0% 74.2%
6g1yA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.56 39.0 3.47e-01 75.0% 73.3%
2wzpP01 2.40.30.210 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › 0.56 49.0 4.38e-01 100.0% 98.2%
3lidA03 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.56 39.0 3.69e-01 75.0% 83.3%
3u9sE04 3.30.700.40 Alpha Beta › 2-Layer Sandwich › Glycoprotein, Type 4 Pilin › 0.54 39.0 3.39e-01 77.6% 77.6%
6u6pA01 3.30.1070.10 Alpha Beta › 2-Layer Sandwich › Cell Cycle; Chain A › Cell division topological specificity factor MinE 0.54 39.0 3.92e-01 76.3% 75.6%
4i86A00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.53 46.0 4.25e-01 100.0% 80.4%
4wqmA02 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.52 41.0 3.81e-01 92.1% 67.3%
2ic2A00 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.52 42.0 3.87e-01 92.1% 69.2%
4d8mA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.52 43.0 3.37e-01 93.4% 42.9%
5xukA00 3.90.470.20 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › 4'-phosphopantetheinyl transferase domain 0.52 36.0 3.23e-01 73.7% 98.3%
3u6xS00 2.60.40.3320 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 37.0 3.40e-01 77.6% 99.0%
2l9pA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.51 37.0 2.92e-01 76.3% 69.5%
2h9fA02 3.10.310.10 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › Diaminopimelate Epimerase; Chain A, domain 1 0.51 42.0 3.28e-01 97.4% 74.1%
1tu1A00 3.40.1000.10 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › Mog1/PsbP, alpha/beta/alpha sandwich 0.51 37.0 3.04e-01 77.6% 63.2%
3hlzB01 3.40.1000.10 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › Mog1/PsbP, alpha/beta/alpha sandwich 0.50 35.0 2.96e-01 72.4% 86.4%
2jeuA02 2.170.200.10 Mainly Beta › Beta Complex › Regulatory Protein E2; Chain: A; Domain 2 › Papillomavirus E2 early protein domain 0.50 41.0 3.82e-01 93.4% 84.2%
3oh8A01 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.50 37.0 3.05e-01 92.1% 42.9%
ECOD (47)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2898325 271.1.1.2 beta barrels › GFP-like › GFP-like › GFP-like 0.78 55.0 3.64e-01 75.0% 19.7%
4946010 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.70 50.0 4.41e-01 75.0% 90.0%
5006332 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.67 48.0 4.63e-01 75.0% 92.9%
3212764 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.64 56.0 5.54e-01 100.0% 95.0%
3176963 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.64 45.0 3.82e-01 75.0% 96.2%
134018 1.1.5.33 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Trypsin_2 0.62 44.0 3.56e-01 100.0% 36.4%
5037075 12.1.1.0 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.62 49.0 4.79e-01 88.2% 83.5%
1780023 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.62 43.0 4.11e-01 75.0% 73.1%
5044798 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.61 43.0 3.90e-01 75.0% 86.7%
3477921 10.32.1.0 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.60 50.0 4.02e-01 93.4% 71.6%
4956411 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.60 37.0 3.58e-01 84.2% 53.3%
4556248 223.1.1.2 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS 0.60 42.0 2.99e-01 75.0% 37.8%
3667522 223.2.1.31 a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_2 0.60 44.0 3.38e-01 78.9% 68.9%
4008731 223.1.1.24 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_8 0.59 44.0 4.20e-01 78.9% 93.3%
4883586 1.1.7.0 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C 0.59 42.0 4.04e-01 88.2% 65.1%
4944566 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.59 42.0 3.75e-01 76.3% 76.5%
3956757 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.59 42.0 3.92e-01 75.0% 60.0%
5050481 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.59 42.0 3.52e-01 76.3% 69.8%
3968427 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.59 42.0 3.38e-01 76.3% 38.7%
4295277 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.58 41.0 3.33e-01 75.0% 38.0%
3930311 220.1.1.176 beta barrels › PH domain-like › PH domain-like › PH domain-like › DUF7778 0.58 41.0 3.51e-01 73.7% 70.0%
4047545 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.58 42.0 3.36e-01 76.3% 40.0%
5001593 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 41.0 3.42e-01 75.0% 64.3%
3943844 1.1.5.25 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ 0.57 50.0 4.63e-01 100.0% 81.0%
3580932 1.1.17.1 beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 2 › Trypsin 0.57 49.0 3.39e-01 100.0% 27.5%
5018085 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.57 49.0 3.67e-01 94.7% 58.4%
3164281 5069.1.1.92 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › CcmF_C 0.57 40.0 3.76e-01 76.3% 98.0%
3964389 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.57 39.0 3.72e-01 73.7% 82.1%
1310612 223.1.1.91 a+b three layers › Profilin-like › sensor domains › sensor domains › TraJ 0.56 40.0 3.52e-01 75.0% 79.3%
4367862 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.56 40.0 3.69e-01 76.3% 88.6%
3345450 1.1.11.1 beta barrels › cradle loop barrel › RIFT-related › Type II restriction endonuclease effector domain › B3 0.56 43.0 3.80e-01 86.8% 54.2%
3249713 5055.1.1.0 extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel 0.56 40.0 3.72e-01 80.3% 60.0%
4018797 301.8.1.1 a+b three layers › Bacillus chorismate mutase-like › 4'-phosphopantetheinyl transferase › 4'-phosphopantetheinyl transferase › ACPS 0.56 40.0 3.13e-01 76.3% 97.0%
4459946 223.1.1.6 a+b three layers › Profilin-like › sensor domains › sensor domains › dCache_1 0.55 40.0 2.87e-01 78.9% 28.6%
4410086 11.1.1.1033 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › PF30215 0.55 45.0 3.45e-01 92.1% 63.8%
4964696 220.1.1.219 beta barrels › PH domain-like › PH domain-like › PH domain-like › CheF-arch 0.55 39.0 3.40e-01 75.0% 74.8%
3722154 301.8.1.1 a+b three layers › Bacillus chorismate mutase-like › 4'-phosphopantetheinyl transferase › 4'-phosphopantetheinyl transferase › ACPS 0.55 39.0 3.09e-01 76.3% 88.5%
4953666 881.1.1.0 a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like 0.54 41.0 3.37e-01 82.9% 69.7%
1558582 5092.1.1.6 beta sandwiches › Domain in virus attachment proteins › Domain in virus attachment proteins › Domain in virus attachment proteins › Fiber_head_BAdV-4 0.53 44.0 3.95e-01 97.4% 70.4%
4399650 223.1.1.59 a+b three layers › Profilin-like › sensor domains › sensor domains › ArlS_N 0.52 37.0 2.95e-01 76.3% 38.9%
4437932 5084.3.1.1 beta barrels › Outer membrane meander beta-barrels › Autotransporter › Autotransporter › Autotransporter 0.52 42.0 2.84e-01 92.1% 92.1%
4938400 220.1.1.219 beta barrels › PH domain-like › PH domain-like › PH domain-like › CheF-arch 0.51 37.0 3.25e-01 75.0% 79.1%
3838331 11.1.1.456 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › YtkA 0.51 43.0 3.86e-01 92.1% 68.6%
3238782 207.1.1.81 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.51 39.0 2.98e-01 85.5% 39.9%
5004871 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.51 37.0 3.50e-01 76.3% 75.6%
3269057 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.51 39.0 3.79e-01 97.4% 73.3%
3528749 11.1.1.179 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ig_3 0.51 41.0 3.49e-01 89.5% 66.2%
D2 medium residues 50-135
PDB
Domain cluster: representative
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 59.0 4.53e-01 81.4% 69.5%
1xioA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.74 61.0 4.53e-01 89.5% 43.3%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.73 66.0 5.78e-01 98.8% 73.4%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.71 64.0 5.53e-01 100.0% 66.2%
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.71 63.0 6.04e-01 96.5% 95.9%
2rpaA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.70 56.0 5.92e-01 98.8% 97.4%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 61.0 5.48e-01 98.8% 76.1%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.67 53.0 5.57e-01 100.0% 96.1%
4ivfA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.67 53.0 4.77e-01 84.9% 75.0%
1yy7A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 51.0 4.83e-01 84.9% 71.4%
4dxwB01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.65 52.0 4.86e-01 88.4% 83.5%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 55.0 4.95e-01 98.8% 78.2%
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.63 52.0 5.27e-01 100.0% 91.8%
2mpkA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.63 48.0 5.12e-01 90.7% 95.9%
1j1jA02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.63 52.0 5.22e-01 100.0% 91.8%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.61 53.0 4.77e-01 97.7% 75.2%
7zb5E01 3.40.50.10810 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Tandem AAA-ATPase domain 0.61 48.0 3.38e-01 87.2% 39.9%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 53.0 5.40e-01 100.0% 100.0%
2p61A00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.61 50.0 4.62e-01 100.0% 70.2%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.60 42.0 4.41e-01 76.7% 80.8%
3nkzA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.54 45.0 4.43e-01 97.7% 91.8%
6f1eA01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.53 43.0 3.73e-01 100.0% 56.1%
ECOD (15)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3686977 4320.1.1.1 alpha superhelices › Taf5 N-terminal domain-like › Taf5 N-terminal domain-like › Taf5 N-terminal domain-like › TFIID_NTD2 0.75 53.0 4.41e-01 82.6% 41.9%
4015874 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.74 55.0 4.24e-01 76.7% 83.4%
3601623 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.73 51.0 5.02e-01 77.9% 68.9%
2393375 633.16.1.1 alpha bundles › Bromodomain-like › PMT helical bundle domain-like › PMT helical bundle domain-like › MLD 0.72 52.0 5.43e-01 94.2% 81.2%
3974221 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.71 61.0 5.36e-01 100.0% 63.1%
5071514 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 56.0 5.96e-01 100.0% 100.0%
3615671 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 58.0 4.25e-01 97.7% 35.5%
3249527 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.66 59.0 5.11e-01 100.0% 83.0%
3504568 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.66 59.0 5.01e-01 100.0% 69.3%
5061845 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.65 59.0 5.60e-01 98.8% 89.0%
3230343 109.54.1.1 alpha superhelices › Repetitive alpha hairpins › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › C-terminal tetramerization domain of Utp1/Utp21/Utp12/Utp13 › Utp12 0.63 50.0 4.46e-01 97.7% 60.8%
3299130 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.61 50.0 5.11e-01 93.0% 100.0%
3782488 6155.1.1.0 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter 0.56 49.0 4.54e-01 98.8% 99.1%
4491397 3843.1.1.1 alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › Oxidored_q2 0.52 43.0 4.42e-01 100.0% 96.5%
3906133 633.21.1.4 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › Cg6151-P 0.51 43.0 4.03e-01 100.0% 73.9%