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ORF42_gene_product

Euk-Vir

Equid_alphaherpesvirus_8

ORF42_gene_product__YP_006273022__Equid_alphaherpesvirus_8__39637

Identity

Accession:: YP_006273022 ↗
Protein ID:: ORF42_gene_product
Kingdom:: euk

Quality

73.8 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Varicellovirus› Equid_alphaherpesvirus_8

TaxID: 39637

Cluster

View cluster (34 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 21-99_114-188

PDB

D2 medium residues 190-261_1103-1116

PDB

Domain cluster: rep: major_capsid_protein__YP_009342387__Spheniscid_alphaherpesvirus_1__2560777__D202-266

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03122.21 best	Herpes_MCP	60.0	1.50e-16	96.5%	5.5%

D3 medium residues 262-305_357-396

PDB

Domain cluster: rep: major_capsid_protein__NP_065524__Alcelaphine_gammaherpesvirus_1__35252__D265-300_361-395

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03122.21 best	Herpes_MCP	37.6	8.80e-10	56.0%	3.2%
PF03122.21	Herpes_MCP	34.1	9.90e-09	48.8%	2.8%

D4 medium residues 469-574

PDB

Domain cluster: rep: major_capsid_protein__YP_009046515__Falconid_herpesvirus_1__1510155__D483-586

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03122.21 best	Herpes_MCP	51.8	4.50e-14	100.0%	6.2%

D5 medium residues 605-617_685-732_749-777

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03122.21 best	Herpes_MCP	32.5	2.90e-08	63.3%	3.5%

ECOD (2)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3315406	110.1.1.32 ↗	alpha arrays › DEATH domain › DEATH domain › DEATH domain › SecA_SW	0.59	41.0	3.82e-01	72.2%	63.5%
2518030	5077.1.1.1 ↗	extended segments › Chlorophyll a-b binding protein › Chlorophyll a-b binding protein › Chlorophyll a-b binding protein › Chloroa_b-bind	0.51	35.0	2.84e-01	73.3%	98.9%

D6 medium residues 618-684_875-905

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03122.21 best	Herpes_MCP	102.2	2.70e-29	70.4%	4.9%

CATH (8)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2ip6A00	1.20.1440.140	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) ›	0.58	39.0	4.14e-01	91.8%	78.2%
1y7yA00	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.56	34.0	3.92e-01	91.8%	85.5%
1j77A00	1.20.910.10	Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like	0.55	45.0	3.65e-01	90.8%	91.5%
4pu7A00	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.55	32.0	3.59e-01	89.8%	77.5%
2bl7A00	1.20.1440.50	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like	0.54	36.0	3.96e-01	91.8%	86.1%
3a06B03	1.10.1740.10	Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif	0.51	31.0	3.27e-01	92.9%	65.9%
1lb3A00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.51	38.0	3.28e-01	81.6%	74.3%
1t33A02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.50	39.0	3.45e-01	86.7%	89.9%

ECOD (14)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
7655	4066.1.1.1 ↗	a+b complex topology › Major capsid protein VP5 › Major capsid protein VP5 › Major capsid protein VP5 › Herpes_MCP	0.97	94.0	5.61e-01	100.0%	53.0%
2116543	4066.1.1.1 ↗	a+b complex topology › Major capsid protein VP5 › Major capsid protein VP5 › Major capsid protein VP5 › Herpes_MCP	0.88	83.0	5.15e-01	100.0%	56.5%
2738095	4066.1.1.1 ↗	a+b complex topology › Major capsid protein VP5 › Major capsid protein VP5 › Major capsid protein VP5 › Herpes_MCP	0.80	73.0	4.59e-01	100.0%	63.3%
3631001	180.1.1.6 ↗	alpha bundles › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › Acid phosphatase/Vanadium-dependent haloperoxidase › FIT	0.55	42.0	3.23e-01	81.6%	72.9%
3725560	150.1.2.19 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › COQ7	0.54	47.0	3.79e-01	99.0%	82.0%
3436831	601.4.1.52 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › Auxin_canalis	0.54	41.0	3.75e-01	80.6%	82.3%
5003109	1079.1.1.1 ↗	alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA › DsbD	0.54	39.0	3.02e-01	76.5%	95.1%
3775900	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.52	43.0	3.45e-01	92.9%	94.2%
3694686	5050.1.1.9 ↗	alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1	0.52	39.0	3.09e-01	82.7%	85.2%
4003778	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.52	43.0	3.22e-01	93.9%	91.5%
3983196	2498.1.1.57 ↗	mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › LPD1	0.51	44.0	3.44e-01	99.0%	77.9%
3940859	150.1.1.4 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › COQ7	0.51	44.0	3.67e-01	99.0%	82.7%
3717149	109.4.1.420 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR	0.51	39.0	3.07e-01	82.7%	48.2%
4194775	150.1.1.4 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › COQ7	0.51	40.0	3.29e-01	87.8%	74.9%

D7 medium residues 1215-1321

PDB