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ORF44
Euk-VirFelis_catus_gammaherpesvirus_1
ORF44__YP_009173920__Felis_catus_gammaherpesvirus_1__1452540
Identity
- Accession:
- YP_009173920 ↗
- Protein ID:
- ORF44
- Kingdom:
- euk
Quality
83.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Percavirus›
Felid_gammaherpesvirus_1
TaxID: 1452540
Cluster
View cluster (90 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 292-355_701-759
Domain cluster:
rep: helicase-primase_ATPase_subunit__YP_010087484__Phascolarctid_gammaherpesvirus_1__2249313__D338-366_706-759
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 109.0 | 2.60e-31 | 54.5% | 8.2% |
| PF02689.21 | Herpes_Helicase | 92.3 | 3.00e-26 | 49.6% | 7.0% |
D2
medium
residues 54-238
Domain cluster:
rep: helicase_subunit__YP_009179342__Elephant_endotheliotropic_herpesvirus_4__548914__D47-64_102-182_199-230
Pfam (3)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 310.5 | 3.20e-92 | 100.0% | 23.5% |
| PF13401.13 | AAA_22 | 27.9 | 3.70e-06 | 95.1% | 76.1% |
| PF13604.13 | AAA_30 | 28.1 | 2.20e-06 | 82.7% | 46.6% |
D3
medium
residues 372-439
Domain cluster:
rep: helicase-primase_helicase_subunit__YP_009252281__Canid_alphaherpesvirus_1__170325__D443-504
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 76.9 | 1.40e-21 | 100.0% | 8.7% |
CATH (64)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3frhA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.75 | 45.0 | 3.27e-01 | 95.6% | 22.4% |
| 4redB01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.70 | 52.0 | 4.77e-01 | 92.6% | 61.9% |
| 3fzgA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.67 | 47.0 | 3.41e-01 | 95.6% | 25.5% |
| 3zh8C01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.66 | 50.0 | 4.14e-01 | 94.1% | 47.0% |
| 3nynA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.66 | 50.0 | 3.87e-01 | 97.1% | 37.4% |
| 2vd5B01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.66 | 52.0 | 3.68e-01 | 98.5% | 29.9% |
| 2acxA02 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.66 | 50.0 | 4.52e-01 | 97.1% | 60.4% |
| 1x19A02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.66 | 42.0 | 3.17e-01 | 95.6% | 27.5% |
| 2dt9A01 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.65 | 44.0 | 4.31e-01 | 95.6% | 64.9% |
| 4c0tA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.64 | 50.0 | 4.47e-01 | 97.1% | 60.9% |
| 3mtjA03 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.64 | 42.0 | 4.08e-01 | 97.1% | 60.5% |
| 5f9eA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.64 | 50.0 | 3.97e-01 | 98.5% | 42.5% |
| 3kgyA00 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.64 | 42.0 | 2.90e-01 | 95.6% | 21.1% |
| 4af3A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.63 | 47.0 | 4.32e-01 | 95.6% | 61.4% |
| 2vz6B01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.63 | 46.0 | 4.30e-01 | 94.1% | 62.7% |
| 5hl8C00 | 3.30.1360.100 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › General secretion pathway protein M, EpsM | 0.62 | 39.0 | 3.76e-01 | 98.5% | 54.4% |
| 1tigA00 | 3.30.110.10 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Translation initiation factor 3 (IF-3), C-terminal domain | 0.62 | 46.0 | 4.30e-01 | 98.5% | 62.5% |
| 3mahA02 | 3.30.70.260 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain | 0.62 | 42.0 | 4.26e-01 | 97.1% | 71.0% |
| 4clfA02 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.62 | 51.0 | 3.75e-01 | 100.0% | 33.7% |
| 2d3o100 | 3.30.70.1050 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Trigger factor ribosome-binding domain | 0.62 | 50.0 | 4.54e-01 | 95.6% | 96.0% |
| 1vi7A02 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 38.0 | 3.80e-01 | 98.5% | 59.2% |
| 3grzB00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.62 | 38.0 | 2.79e-01 | 95.6% | 21.8% |
| 4nfnA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.62 | 43.0 | 4.47e-01 | 97.1% | 78.1% |
| 2rkuA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.61 | 47.0 | 4.31e-01 | 98.5% | 62.9% |
| 3qwuA03 | 3.30.70.2160 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 45.0 | 3.55e-01 | 100.0% | 38.8% |
| 2r7rA04 | 3.30.70.2480 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 44.0 | 3.33e-01 | 98.5% | 33.8% |
| 5i2cB01 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.60 | 39.0 | 3.06e-01 | 100.0% | 30.8% |
| 2rioA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.60 | 40.0 | 3.76e-01 | 92.6% | 57.3% |
| 1vx4407 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 38.0 | 3.87e-01 | 98.5% | 65.2% |
| 2obdA01 | 3.15.20.10 | Alpha Beta › Super Roll › Bactericidal permeability-increasing protein; domain 2 › Bactericidal permeability-increasing protein; domain 2 | 0.59 | 49.0 | 3.38e-01 | 100.0% | 72.4% |
| 1b24A01 | 3.10.28.10 | Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases | 0.59 | 40.0 | 3.67e-01 | 97.1% | 51.6% |
| 2c47A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.59 | 41.0 | 4.05e-01 | 95.6% | 68.5% |
| 2khdA00 | 3.30.70.860 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.58 | 42.0 | 3.68e-01 | 97.1% | 49.1% |
| 5fqdC01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.58 | 41.0 | 4.23e-01 | 95.6% | 78.1% |
| 2xzsA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.58 | 44.0 | 4.01e-01 | 97.1% | 60.4% |
| 2bkkA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.58 | 41.0 | 3.74e-01 | 92.6% | 55.6% |
| 2imqX00 | 3.60.10.10 | Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase | 0.58 | 43.0 | 2.92e-01 | 98.5% | 19.6% |
| 6lbsB01 | 3.30.1370.230 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › Stn1, C-terminal wHTH domain | 0.58 | 45.0 | 4.37e-01 | 97.1% | 77.2% |
| 2xglA00 | 3.10.450.300 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › YebF/Colicin-M immunity protein | 0.58 | 44.0 | 4.05e-01 | 83.8% | 81.3% |
| 5mmjh01 | 3.30.1370.30 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › | 0.57 | 38.0 | 3.68e-01 | 100.0% | 61.3% |
| 3tviA02 | 3.30.2130.10 | Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like | 0.57 | 39.0 | 3.09e-01 | 97.1% | 30.8% |
| 2k3iA01 | 3.30.70.860 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.56 | 42.0 | 3.96e-01 | 100.0% | 65.9% |
| 4nzrM03 | 3.30.110.180 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › | 0.55 | 46.0 | 3.86e-01 | 95.6% | 78.0% |
| 1vbkA01 | 3.30.70.1510 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › THUMP domain-like | 0.55 | 40.0 | 3.84e-01 | 95.6% | 66.3% |
| 4oi3A00 | 3.30.70.3090 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ORF SCO4226, nickel-binding ferredoxin-like monomer | 0.55 | 39.0 | 3.80e-01 | 98.5% | 65.4% |
| 3bzmA00 | 3.60.120.10 | Alpha Beta › 4-Layer Sandwich › Anthranilate synthase › Anthranilate synthase | 0.55 | 47.0 | 2.94e-01 | 100.0% | 18.2% |
| 2cxiA01 | 3.30.56.10 | Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › | 0.54 | 39.0 | 3.75e-01 | 98.5% | 65.8% |
| 1tuwA00 | 3.30.70.1090 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. | 0.54 | 40.0 | 3.50e-01 | 98.5% | 50.9% |
| 4feuF01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.54 | 36.0 | 3.56e-01 | 92.6% | 64.4% |
| 3keyA02 | 3.30.1370.230 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › Stn1, C-terminal wHTH domain | 0.54 | 44.0 | 4.17e-01 | 100.0% | 75.0% |
| 2weiA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.54 | 39.0 | 3.65e-01 | 97.1% | 60.0% |
| 4a9cA00 | 3.60.10.10 | Alpha Beta › 4-Layer Sandwich › Deoxyribonuclease I; Chain A › Endonuclease/exonuclease/phosphatase | 0.53 | 46.0 | 3.08e-01 | 100.0% | 98.6% |
| 3ssmC02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.53 | 43.0 | 3.09e-01 | 97.1% | 29.4% |
| 3qkbA00 | 3.30.110.70 | Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Hypothetical protein apc22750. Chain B | 0.53 | 46.0 | 4.17e-01 | 98.5% | 77.7% |
| 2f5gA00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.53 | 39.0 | 3.28e-01 | 98.5% | 43.1% |
| 2qv6B02 | 3.30.70.270 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain | 0.53 | 39.0 | 3.38e-01 | 97.1% | 46.7% |
| 7xc2A02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 38.0 | 3.38e-01 | 95.6% | 51.9% |
| 7qh2C03 | 3.30.70.2740 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 36.0 | 3.51e-01 | 100.0% | 65.4% |
| 2di7A01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 40.0 | 3.48e-01 | 98.5% | 55.1% |
| 4er8A00 | 3.30.70.1290 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like | 0.51 | 38.0 | 3.01e-01 | 100.0% | 34.5% |
| 1jg5A00 | 3.30.1410.10 | Alpha Beta › 2-Layer Sandwich › Gtp Cyclohydrolase I Feedback Regulatory Protein; Chain: K › GTP cyclohydrolase I feedback regulatory protein GFRP | 0.51 | 44.0 | 4.14e-01 | 95.6% | 97.6% |
| 2phcB01 | 3.30.1360.40 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › | 0.51 | 35.0 | 3.35e-01 | 100.0% | 60.2% |
| 4esbA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 35.0 | 3.06e-01 | 80.9% | 47.6% |
| 3uebF00 | 3.30.300.100 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › MTH677-like | 0.51 | 41.0 | 3.72e-01 | 100.0% | 65.0% |
ECOD (44)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5014008 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.70 | 50.0 | 5.10e-01 | 98.5% | 76.9% |
| 4516880 | 304.8.1.74 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › PF26539 | 0.69 | 44.0 | 4.17e-01 | 97.1% | 55.0% |
| 4934956 | 310.3.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › General secretion pathway protein M (EpsM) periplasmic domain-related › General secretion pathway protein M (EpsM) periplasmic domain-related | 0.68 | 50.0 | 4.68e-01 | 98.5% | 63.5% |
| 4023676 | 3156.3.1.0 ↗ | beta sandwiches › Cupredoxin-like › Surface antigen 1 (SAG1)-related-sequence (SRS) family › Surface antigen 1 (SAG1)-related-sequence (SRS) family | 0.67 | 49.0 | 3.87e-01 | 100.0% | 37.9% |
| 3969035 | 304.24.1.2 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › DUF1949 | 0.66 | 41.0 | 4.12e-01 | 98.5% | 61.4% |
| 4951601 | 304.24.1.37 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › MCR_C | 0.65 | 40.0 | 4.11e-01 | 97.1% | 64.6% |
| 4978126 | 304.39.1.0 ↗ | a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain | 0.64 | 48.0 | 4.61e-01 | 100.0% | 70.5% |
| 4975452 | 873.1.1.0 ↗ | a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain | 0.64 | 49.0 | 4.15e-01 | 95.6% | 49.6% |
| 4514876 | 812.1.1.1 ↗ | a+b duplicates or obligate multimers › MinE-like › Cell division protein MinE topological specificity domain › Cell division protein MinE topological specificity domain › MinE | 0.64 | 48.0 | 4.80e-01 | 100.0% | 80.0% |
| 4939665 | 304.120.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI | 0.63 | 43.0 | 4.16e-01 | 95.6% | 62.7% |
| 3928382 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.63 | 48.0 | 4.43e-01 | 98.5% | 63.3% |
| 3413369 | 304.151.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase | 0.61 | 52.0 | 4.33e-01 | 100.0% | 60.0% |
| 5030922 | 304.24.1.37 ↗ | a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › MCR_C | 0.61 | 38.0 | 3.88e-01 | 97.1% | 64.6% |
| 3238562 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.61 | 46.0 | 4.16e-01 | 98.5% | 58.0% |
| 3236767 | 4955.1.1.0 ↗ | a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit | 0.60 | 53.0 | 4.77e-01 | 100.0% | 76.8% |
| 4561991 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.60 | 40.0 | 4.07e-01 | 95.6% | 72.3% |
| 3689188 | 206.1.1.70 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 | 0.59 | 53.0 | 3.39e-01 | 100.0% | 40.6% |
| 3605723 | 320.1.1.0 ↗ | a+b two layers › R3H domain-like › R3H domain › R3H domain | 0.59 | 44.0 | 4.28e-01 | 98.5% | 71.2% |
| 3519431 | 256.1.1.0 ↗ | a+b two layers › MTH1598-like › MTH1598-like › MTH1598-like | 0.59 | 50.0 | 5.13e-01 | 98.5% | 98.5% |
| 3763545 | 304.47.1.0 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain | 0.58 | 48.0 | 4.20e-01 | 100.0% | 66.1% |
| 4555558 | 304.120.1.6 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI › ThiI_fer | 0.57 | 42.0 | 4.17e-01 | 98.5% | 74.7% |
| 3900096 | 206.1.1.70 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 | 0.56 | 50.0 | 3.25e-01 | 100.0% | 36.3% |
| 3997847 | 304.151.1.0 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase › Ferredoxin-like domain of receptor-type protein tyrosine phosphatase | 0.55 | 40.0 | 3.57e-01 | 89.7% | 53.0% |
| 3220882 | 304.8.1.0 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like | 0.55 | 47.0 | 4.20e-01 | 100.0% | 71.0% |
| 4983717 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.55 | 39.0 | 3.09e-01 | 77.9% | 91.0% |
| 4998240 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.55 | 49.0 | 3.54e-01 | 98.5% | 37.0% |
| 3897519 | 304.47.1.1 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA | 0.54 | 46.0 | 4.04e-01 | 100.0% | 70.0% |
| 3176326 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.54 | 49.0 | 3.02e-01 | 100.0% | 32.8% |
| 3195155 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.54 | 38.0 | 3.79e-01 | 98.5% | 72.9% |
| 1145702 | 101.1.2.134 ↗ | alpha arrays › HTH › HTH › winged helix domain › Stn1_C | 0.54 | 44.0 | 4.16e-01 | 100.0% | 74.2% |
| 3496468 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.54 | 48.0 | 3.05e-01 | 100.0% | 31.5% |
| 5011183 | 101.1.2.101 ↗ | alpha arrays › HTH › HTH › winged helix domain › Cdc6_C | 0.54 | 41.0 | 3.61e-01 | 86.8% | 81.8% |
| 3485848 | 304.47.1.0 ↗ | a+b two layers › Alpha-beta plaits › SEA domain › SEA domain | 0.54 | 45.0 | 4.14e-01 | 100.0% | 82.1% |
| 3758554 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.53 | 48.0 | 3.11e-01 | 100.0% | 80.6% |
| 3545474 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.53 | 39.0 | 3.67e-01 | 100.0% | 62.2% |
| 5002487 | 304.55.2.1 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp | 0.53 | 40.0 | 3.27e-01 | 98.5% | 42.2% |
| 4974589 | 3501.1.1.1 ↗ | a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 | 0.53 | 38.0 | 3.54e-01 | 98.5% | 60.7% |
| 4976066 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.52 | 38.0 | 3.64e-01 | 79.4% | 73.8% |
| 3231541 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.52 | 47.0 | 3.06e-01 | 100.0% | 38.0% |
| 3236712 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.52 | 47.0 | 2.99e-01 | 100.0% | 33.2% |
| 3923678 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.51 | 45.0 | 2.87e-01 | 100.0% | 74.6% |
| 3792911 | 101.1.2.312 ↗ | alpha arrays › HTH › HTH › winged helix domain › MSC | 0.51 | 38.0 | 3.31e-01 | 83.8% | 54.8% |
| 5051424 | 304.4.1.3 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › YCII | 0.51 | 41.0 | 3.74e-01 | 97.1% | 65.3% |
| 3986660 | 304.55.2.0 ↗ | a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like | 0.50 | 37.0 | 3.38e-01 | 100.0% | 57.0% |
D4
medium
residues 440-455_598-699
Domain cluster:
rep: helicase-primase_helicase_subunit__YP_009137079__Human_alphaherpesvirus_1__10298__D496-518_696-779
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 115.9 | 2.20e-33 | 87.3% | 12.5% |
D5
medium
residues 456-476_506-538_568-597
D6
medium
residues 477-505_539-567
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 31.2 | 9.00e-08 | 58.6% | 3.8% |
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1dvkA00 | 1.20.940.10 | Mainly Alpha › Up-down Bundle › RNA Binding Protein, Prp18; Chain A › Functional domain of the splicing factor Prp18 | 0.69 | 58.0 | 4.45e-01 | 100.0% | 45.6% |
| 4lqqB00 | 1.20.140.30 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › MOB kinase activator | 0.69 | 59.0 | 4.48e-01 | 100.0% | 49.3% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.65 | 46.0 | 4.05e-01 | 75.9% | 51.7% |
| 3ledA01 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.57 | 49.0 | 3.34e-01 | 98.3% | 81.3% |
| 2dt5B01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 39.0 | 3.64e-01 | 74.1% | 69.9% |
| 3bg2A02 | 1.10.3550.10 | Mainly Alpha › Orthogonal Bundle › eoxyguanosinetriphosphate triphosphohydrolase fold › eoxyguanosinetriphosphate triphosphohydrolase domain-like | 0.54 | 46.0 | 3.80e-01 | 98.3% | 58.9% |
| 1b04A03 | 1.10.287.610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.54 | 39.0 | 3.84e-01 | 79.3% | 79.0% |
| 1ds8M02 | 1.20.85.10 | Mainly Alpha › Up-down Bundle › Photosynthetic Reaction Center, subunit M; domain 1 › Photosystem II protein D1-like | 0.53 | 45.0 | 3.35e-01 | 98.3% | 88.0% |
| 3natA01 | 3.40.50.11250 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Protein of unknown function DUF3013 | 0.53 | 41.0 | 3.11e-01 | 86.2% | 90.5% |
| 4ertA01 | 1.10.490.160 | Mainly Alpha › Orthogonal Bundle › Globin-like › | 0.52 | 44.0 | 3.29e-01 | 100.0% | 35.6% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3267097 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.63 | 52.0 | 4.01e-01 | 94.8% | 53.6% |
| 3481034 | 4009.1.1.0 ↗ | alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins | 0.59 | 51.0 | 4.62e-01 | 98.3% | 82.5% |
| 3636451 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.58 | 38.0 | 3.48e-01 | 98.3% | 48.8% |
| 3270180 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.54 | 44.0 | 3.86e-01 | 91.4% | 74.4% |