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ORF44
Euk-VirOvine_gammaherpesvirus_2
ORF44__YP_438166__Ovine_gammaherpesvirus_2__10398
Identity
- Accession:
- YP_438166 ↗
- Protein ID:
- ORF44
- Kingdom:
- euk
Quality
82.4
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Macavirus›
Ovine_gammaherpesvirus_2
TaxID: 10398
Cluster
View cluster (90 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 153-263
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 147.9 | 4.50e-43 | 100.0% | 13.7% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3lkdB01 | 1.20.1260.30 | Mainly Alpha › Up-down Bundle › Ferritin › N6 adenine-specific DNA methyltransferase, N-terminal domain | 0.57 | 40.0 | 3.44e-01 | 73.0% | 83.2% |
D2
medium
residues 279-333
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 86.6 | 1.50e-24 | 100.0% | 6.8% |
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3wqbA02 | 2.60.120.260 | Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like | 0.60 | 37.0 | 2.68e-01 | 78.2% | 19.3% |
| 2ebnA00 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.55 | 45.0 | 2.94e-01 | 98.2% | 91.9% |
| 3i3lA02 | 3.30.390.160 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › | 0.55 | 37.0 | 2.90e-01 | 70.9% | 40.8% |
| 2qrdE01 | 3.10.580.10 | Alpha Beta › Roll › CBS-domain › CBS-domain | 0.54 | 40.0 | 2.89e-01 | 87.3% | 25.6% |
| 4hadB02 | 3.30.360.10 | Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 | 0.52 | 37.0 | 2.59e-01 | 74.5% | 21.0% |
| 6fezA02 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.52 | 36.0 | 3.04e-01 | 89.1% | 42.6% |
| 1zoyA04 | 4.10.80.40 | Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › succinate dehydrogenase protein domain | 0.52 | 42.0 | 4.06e-01 | 94.5% | 92.3% |
| 1k8kA04 | 3.90.640.10 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 | 0.51 | 36.0 | 3.08e-01 | 72.7% | 43.5% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3212521 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.67 | 43.0 | 2.66e-01 | 78.2% | 11.2% |
| 5018200 | 2004.1.1.220 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SWI2_SNF2 | 0.59 | 38.0 | 2.21e-01 | 76.4% | 7.0% |
| 4242930 | 4232.1.1.1 ↗ | few secondary structure elements › Ribosomal protein bL28-related › Ribosomal protein bL28-related › Ribosomal protein L28 › Ribosomal_L28 | 0.58 | 44.0 | 3.87e-01 | 87.3% | 100.0% |
| 3171046 | 320.4.1.0 ↗ | a+b two layers › R3H domain-like › PUB domain › PUB domain | 0.58 | 38.0 | 2.76e-01 | 78.2% | 21.1% |
| 3480627 | 59.1.3.0 ↗ | beta complex topology › triple barrel › triple barrel › RNA polymerase I subunits A49/A34.5 dimerization domains | 0.55 | 34.0 | 3.11e-01 | 78.2% | 41.2% |
| 3995122 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 41.0 | 2.83e-01 | 89.1% | 28.4% |
| 3649913 | 5050.1.1.58 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › NFD4_C | 0.54 | 37.0 | 2.68e-01 | 78.2% | 23.5% |
| 3354637 | 3357.1.1.2 ↗ | extended segments › DCP1-binding motif › DCP1-binding motif › DCP1-binding motif › PH_TRF2_HOY1 | 0.54 | 33.0 | 3.68e-01 | 90.9% | 85.0% |
| 1765248 | 604.2.1.0 ↗ | alpha bundles › Spectrin repeat-like › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 0.53 | 42.0 | 3.13e-01 | 85.5% | 33.8% |
| 5040519 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.52 | 35.0 | 2.31e-01 | 92.7% | 14.6% |
| 3199254 | 604.6.1.41 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF846 | 0.50 | 37.0 | 2.88e-01 | 100.0% | 33.3% |
D3
medium
residues 365-407_757-812
Domain cluster:
rep: helicase-primase_ATPase_subunit__YP_010087484__Phascolarctid_gammaherpesvirus_1__2249313__D338-366_706-759
Pfam (3)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01443.25 best | Viral_helicase1 | 23.3 | 7.20e-05 | 77.8% | 21.1% |
| PF02689.21 | Herpes_Helicase | 78.0 | 6.10e-22 | 58.6% | 6.4% |
| PF02689.21 | Herpes_Helicase | 58.2 | 6.10e-16 | 44.4% | 5.1% |
D4
medium
residues 408-486_725-756
Domain cluster:
rep: helicase-primase_helicase_subunit__NP_045354__Bovine_alphaherpesvirus_1__10320__D392-469_736-760
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 96.5 | 1.60e-27 | 74.8% | 10.2% |
| PF02689.21 | Herpes_Helicase | 34.0 | 1.20e-08 | 28.8% | 3.8% |
D5
medium
residues 487-509_638-689_701-724
Domain cluster:
rep: helicase-primase_helicase_subunit__YP_009137079__Human_alphaherpesvirus_1__10298__D496-518_696-779
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 74.6 | 6.60e-21 | 79.8% | 11.1% |
D6
medium
residues 510-573_589-637
Domain cluster:
rep: helicase-primase_helicase_subunit__YP_004940266__Saimiriine_betaherpesvirus_4__1535247__D509-572_638-677
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02689.21 best | Herpes_Helicase | 57.7 | 8.70e-16 | 58.4% | 7.4% |
| PF02689.21 | Herpes_Helicase | 31.6 | 6.70e-08 | 49.6% | 6.2% |