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ORF49
Euk-VirRetroperitoneal_fibromatosis-associated_herpesvirus
ORF49__YP_010084412__Retroperitoneal_fibromatosis-associated_herpesvirus__111469
Identity
- Accession:
- YP_010084412 ↗
- Protein ID:
- ORF49
- Kingdom:
- euk
Quality
89.9
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Rhadinovirus›
Retroperitoneal_fibromatosis-associated_herpesvirus
TaxID: 111469
Cluster
View cluster (19 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 38-68_230-299
Domain cluster:
rep: protein_G49__YP_009388550__Common_bottlenose_dolphin_gammaherpesvirus_1_strain_Sarasota__2022783__D19-71_232-304
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04793.18 best | Herpes_BBRF1 | 57.0 | 2.20e-15 | 70.3% | 26.6% |
| PF04793.18 | Herpes_BBRF1 | 26.5 | 4.70e-06 | 38.6% | 11.2% |
D2
medium
residues 72-138
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04793.18 best | Herpes_BBRF1 | 52.5 | 5.50e-14 | 100.0% | 22.0% |
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.81 | 65.0 | 5.63e-01 | 88.1% | 74.5% |
| 4n06A02 | 1.20.120.920 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain | 0.76 | 66.0 | 4.45e-01 | 100.0% | 38.3% |
| 3m7gA02 | 1.10.8.1010 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.74 | 59.0 | 5.29e-01 | 88.1% | 88.4% |
| 1jalA03 | 1.10.150.300 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain | 0.74 | 56.0 | 5.28e-01 | 82.1% | 80.2% |
| 1lq7A00 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.71 | 53.0 | 5.39e-01 | 83.6% | 98.5% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.68 | 54.0 | 5.32e-01 | 91.0% | 98.6% |
| 3q8dA02 | 1.20.1440.120 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Recombination protein O, C-terminal domain | 0.68 | 57.0 | 4.45e-01 | 97.0% | 79.9% |
| 4m0mA03 | 1.20.1270.430 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.67 | 53.0 | 5.08e-01 | 88.1% | 87.3% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 58.0 | 4.50e-01 | 100.0% | 83.1% |
| 2k19A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.66 | 56.0 | 5.00e-01 | 97.0% | 87.8% |
| 3t46A00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.63 | 51.0 | 4.93e-01 | 88.1% | 92.0% |
| 2ee7A01 | 1.10.418.10 | Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Calponin-like domain | 0.59 | 47.0 | 4.04e-01 | 95.5% | 53.0% |
| 6mh4A03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.57 | 42.0 | 4.02e-01 | 80.6% | 73.4% |
| 2b5dX01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.54 | 43.0 | 2.72e-01 | 92.5% | 56.7% |
| 2g8lA02 | 1.10.285.20 | Mainly Alpha › Orthogonal Bundle › Glutamate Dehydrogenase; Chain A, domain 3 › Uncharacterised protein PF01937, DUF89, domain 2 | 0.51 | 38.0 | 3.90e-01 | 83.6% | 83.1% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1923803 | 1120.1.1.1 ↗ | alpha bundles › KSHV ORF49 protein › KSHV ORF49 protein › KSHV ORF49 protein › Herpes_BBRF1 | 0.89 | 84.0 | 5.34e-01 | 100.0% | 23.8% |
| 3992687 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.78 | 65.0 | 4.57e-01 | 91.0% | 65.0% |
| 3618461 | 632.22.1.29 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › 7tm_1 | 0.76 | 59.0 | 5.15e-01 | 85.1% | 85.6% |
| 3192608 | 5001.1.1.6 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Bac_rhodopsin | 0.75 | 61.0 | 4.02e-01 | 89.6% | 76.1% |
| 3830161 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.73 | 56.0 | 4.40e-01 | 85.1% | 69.0% |
| 4951259 | 601.14.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin | 0.72 | 58.0 | 4.60e-01 | 91.0% | 60.7% |
| 4956241 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.72 | 56.0 | 5.50e-01 | 88.1% | 98.7% |
| 3681387 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.71 | 57.0 | 4.76e-01 | 89.6% | 73.3% |
| 3388736 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.70 | 57.0 | 4.39e-01 | 86.6% | 87.1% |
| 3999152 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.68 | 52.0 | 4.34e-01 | 85.1% | 68.8% |
| 3389454 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.62 | 52.0 | 4.45e-01 | 100.0% | 80.8% |
| 3731708 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.62 | 47.0 | 4.20e-01 | 86.6% | 91.4% |
| 3614667 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.59 | 51.0 | 3.28e-01 | 100.0% | 73.0% |
D3
medium
residues 139-229
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04793.18 best | Herpes_BBRF1 | 79.8 | 2.70e-22 | 100.0% | 29.7% |
CATH (58)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.71 | 53.0 | 5.15e-01 | 80.2% | 71.7% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.70 | 55.0 | 5.20e-01 | 84.6% | 96.3% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.68 | 54.0 | 5.07e-01 | 85.7% | 95.5% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.68 | 60.0 | 5.73e-01 | 98.9% | 100.0% |
| 3f0cA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.68 | 53.0 | 4.55e-01 | 83.5% | 63.9% |
| 6wh0A01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.67 | 50.0 | 4.25e-01 | 84.6% | 48.0% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.66 | 48.0 | 4.49e-01 | 75.8% | 66.4% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.66 | 52.0 | 4.76e-01 | 84.6% | 88.1% |
| 5cwhA01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.65 | 42.0 | 3.56e-01 | 80.2% | 38.5% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.65 | 51.0 | 5.46e-01 | 85.7% | 98.7% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 50.0 | 4.52e-01 | 82.4% | 82.0% |
| 4uyeA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.64 | 52.0 | 4.97e-01 | 91.2% | 90.8% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 49.0 | 4.69e-01 | 83.5% | 91.5% |
| 1s35A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 48.0 | 4.68e-01 | 82.4% | 96.0% |
| 3f7cA00 | 1.20.1590.10 | Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like | 0.63 | 53.0 | 4.14e-01 | 94.5% | 51.8% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.62 | 48.0 | 4.83e-01 | 83.5% | 89.0% |
| 4hwhE00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.62 | 48.0 | 4.88e-01 | 83.5% | 93.2% |
| 6tkyA03 | 1.20.58.740 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › DOCK DHR2 domain, lobe C | 0.62 | 48.0 | 4.35e-01 | 83.5% | 74.6% |
| 4mhlA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.61 | 55.0 | 4.54e-01 | 98.9% | 67.1% |
| 3lbxB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 47.0 | 4.53e-01 | 83.5% | 91.6% |
| 2vixA03 | 1.20.1280.240 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.61 | 46.0 | 4.28e-01 | 83.5% | 63.7% |
| 5c8gB00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.61 | 49.0 | 4.55e-01 | 87.9% | 83.8% |
| 1xl3C00 | 1.20.1280.80 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.61 | 44.0 | 4.50e-01 | 91.2% | 78.0% |
| 4hwdD00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.61 | 47.0 | 4.74e-01 | 83.5% | 94.4% |
| 2vj4A01 | 1.10.10.2060 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.61 | 43.0 | 4.34e-01 | 96.7% | 74.4% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.60 | 45.0 | 4.75e-01 | 80.2% | 94.8% |
| 3msyA01 | 3.30.390.10 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain | 0.60 | 50.0 | 4.72e-01 | 91.2% | 91.9% |
| 4lixA03 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.60 | 53.0 | 3.96e-01 | 98.9% | 72.0% |
| 1bgcA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.60 | 54.0 | 4.52e-01 | 100.0% | 71.5% |
| 3ztaA00 | 1.10.490.130 | Mainly Alpha › Orthogonal Bundle › Globin-like › | 0.60 | 52.0 | 4.48e-01 | 93.4% | 66.2% |
| 3whjA00 | 6.10.140.1710 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 46.0 | 4.36e-01 | 83.5% | 82.0% |
| 4egwA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.60 | 47.0 | 4.30e-01 | 84.6% | 90.8% |
| 5ko4A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.60 | 47.0 | 4.57e-01 | 86.8% | 93.1% |
| 1s0pA01 | 1.25.40.330 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Adenylate cyclase-associated CAP, N-terminal domain | 0.60 | 51.0 | 4.25e-01 | 98.9% | 94.2% |
| 2ys8A00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.59 | 44.0 | 4.51e-01 | 83.5% | 80.0% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 45.0 | 4.39e-01 | 83.5% | 90.1% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 48.0 | 4.05e-01 | 90.1% | 64.3% |
| 4i4cB00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.58 | 48.0 | 3.24e-01 | 94.5% | 67.6% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.58 | 45.0 | 4.26e-01 | 83.5% | 94.5% |
| 2dfkC01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.57 | 49.0 | 3.85e-01 | 98.9% | 77.4% |
| 1v4aA01 | 1.10.4050.10 | Mainly Alpha › Orthogonal Bundle › Nucleotidyltransferase substrate binding subunit/domain fold › Glutamine synthase adenylyltransferase GlnE | 0.57 | 52.0 | 4.87e-01 | 100.0% | 82.6% |
| 2qwoB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.57 | 46.0 | 4.58e-01 | 97.8% | 87.0% |
| 3anwB00 | 1.20.58.2050 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 43.0 | 3.61e-01 | 82.4% | 51.2% |
| 1ie9A00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.56 | 50.0 | 3.66e-01 | 100.0% | 54.5% |
| 1ll1A01 | 1.20.1370.10 | Mainly Alpha › Up-down Bundle › Hemocyanin, N-terminal domain › Hemocyanin, N-terminal domain | 0.56 | 36.0 | 3.54e-01 | 84.6% | 58.6% |
| 4nbqB02 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.56 | 43.0 | 4.49e-01 | 86.8% | 93.9% |
| 1nigA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.56 | 49.0 | 4.23e-01 | 98.9% | 71.2% |
| 5c9eB01 | 1.20.1280.80 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.56 | 40.0 | 4.11e-01 | 92.3% | 79.3% |
| 1g2nA00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.55 | 48.0 | 3.60e-01 | 100.0% | 49.6% |
| 3kavA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.55 | 48.0 | 4.66e-01 | 98.9% | 94.1% |
| 3u5nA02 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.54 | 47.0 | 4.38e-01 | 98.9% | 89.2% |
| 4nx8B00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.54 | 47.0 | 3.41e-01 | 97.8% | 39.0% |
| 1e6bA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.53 | 38.0 | 3.57e-01 | 76.9% | 62.2% |
| 4ivfA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 37.0 | 3.49e-01 | 76.9% | 74.1% |
| 2ijeS00 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.51 | 39.0 | 2.96e-01 | 83.5% | 33.3% |
| 4f0cA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 38.0 | 3.36e-01 | 80.2% | 62.3% |
| 3qthB00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.51 | 45.0 | 3.76e-01 | 100.0% | 61.0% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.51 | 39.0 | 4.07e-01 | 81.3% | 96.3% |
ECOD (50)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1923803 | 1120.1.1.1 ↗ | alpha bundles › KSHV ORF49 protein › KSHV ORF49 protein › KSHV ORF49 protein › Herpes_BBRF1 | 0.89 | 84.0 | 5.66e-01 | 98.9% | 36.5% |
| 4034213 | 632.2.1.5 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › DUF1542 | 0.75 | 41.0 | 4.43e-01 | 97.8% | 62.5% |
| 3371343 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.74 | 58.0 | 4.58e-01 | 83.5% | 81.7% |
| 3494149 | 601.1.2.6 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B | 0.71 | 64.0 | 5.21e-01 | 98.9% | 75.8% |
| 3659915 | 192.7.1.45 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Na_sulph_symp | 0.69 | 54.0 | 5.82e-01 | 86.8% | 100.0% |
| 3497021 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.69 | 47.0 | 4.53e-01 | 85.7% | 61.0% |
| 3405750 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.66 | 57.0 | 5.12e-01 | 95.6% | 82.4% |
| 3744146 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.65 | 51.0 | 5.14e-01 | 82.4% | 93.3% |
| 3261803 | 633.24.1.0 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain | 0.65 | 47.0 | 4.86e-01 | 75.8% | 91.8% |
| 3570983 | 6103.1.1.1 ↗ | alpha bundles › Death domain-associated protein 6 histone binding domain › Death domain-associated protein 6 histone binding domain › Death domain-associated protein 6 histone binding domain › DAXX_hist_bd | 0.65 | 54.0 | 4.10e-01 | 95.6% | 39.0% |
| 3527888 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.65 | 56.0 | 4.49e-01 | 96.7% | 56.2% |
| 3282593 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.65 | 50.0 | 3.71e-01 | 83.5% | 50.0% |
| 3952930 | 604.6.1.28 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › PF30641 | 0.64 | 50.0 | 4.88e-01 | 83.5% | 85.0% |
| 3581261 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 50.0 | 4.96e-01 | 83.5% | 94.7% |
| 3645751 | 633.26.1.0 ↗ | alpha bundles › Bromodomain-like › SidC lipid-binding domain › SidC lipid-binding domain | 0.64 | 57.0 | 4.91e-01 | 100.0% | 75.2% |
| 3431182 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.64 | 57.0 | 4.91e-01 | 100.0% | 76.6% |
| 3373083 | 206.1.1.83 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1, PK_Tyr_Ser-Thr | 0.64 | 57.0 | 3.59e-01 | 100.0% | 20.8% |
| 3214191 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 50.0 | 4.61e-01 | 83.5% | 92.2% |
| 3368195 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.64 | 57.0 | 4.77e-01 | 100.0% | 78.1% |
| 3954514 | 604.5.1.61 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PF30641 | 0.63 | 49.0 | 4.79e-01 | 83.5% | 86.7% |
| 3918790 | 626.1.1.1 ↗ | alpha complex topology › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain) › FH2 | 0.62 | 48.0 | 3.44e-01 | 83.5% | 66.7% |
| 3259409 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.62 | 55.0 | 4.78e-01 | 98.9% | 71.4% |
| 3683769 | 206.1.1.70 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, ABC1 | 0.62 | 53.0 | 3.39e-01 | 95.6% | 24.5% |
| 3246610 | 109.26.1.6 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › TPR_NUP160_120_M | 0.62 | 48.0 | 3.10e-01 | 83.5% | 20.0% |
| 4018774 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.62 | 53.0 | 4.50e-01 | 95.6% | 84.0% |
| 3831168 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 54.0 | 4.73e-01 | 100.0% | 78.6% |
| 5028850 | 633.12.1.1 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › UPF0147 | 0.61 | 49.0 | 5.14e-01 | 94.5% | 96.4% |
| 3220017 | 174.1.1.13 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2700 | 0.61 | 53.0 | 4.60e-01 | 98.9% | 100.0% |
| 3268298 | 633.24.1.2 ↗ | alpha bundles › Bromodomain-like › RABEX-5 helical domain › RABEX-5 helical domain › DUF5601 | 0.61 | 48.0 | 4.75e-01 | 85.7% | 85.3% |
| 4662540 | 633.31.1.0 ↗ | alpha bundles › Bromodomain-like › Four-helical bundle insertion domain in pyruvate-ferredoxin oxidoreductase › Four-helical bundle insertion domain in pyruvate-ferredoxin oxidoreductase | 0.61 | 47.0 | 5.06e-01 | 89.0% | 100.0% |
| 3541263 | 604.1.1.227 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27002 | 0.61 | 47.0 | 4.05e-01 | 82.4% | 77.2% |
| 3895658 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.61 | 47.0 | 4.47e-01 | 83.5% | 91.8% |
| 4973584 | 604.3.1.51 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › 8xMP | 0.61 | 45.0 | 4.57e-01 | 79.1% | 92.0% |
| 3329547 | 604.6.1.22 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 | 0.60 | 48.0 | 4.51e-01 | 85.7% | 80.9% |
| 3872651 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 43.0 | 3.09e-01 | 74.7% | 26.5% |
| 4011740 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.59 | 44.0 | 4.29e-01 | 79.1% | 82.0% |
| 3504301 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 45.0 | 4.30e-01 | 82.4% | 91.8% |
| 3736843 | 109.4.1.681 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 | 0.58 | 50.0 | 3.40e-01 | 97.8% | 54.8% |
| 3439128 | 650.1.1.1 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ | 0.57 | 43.0 | 4.36e-01 | 98.9% | 82.2% |
| 4999401 | 4995.1.1.0 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like | 0.57 | 46.0 | 4.74e-01 | 87.9% | 94.1% |
| 3805617 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.56 | 47.0 | 4.07e-01 | 97.8% | 72.9% |
| 3839303 | 650.1.1.1 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ | 0.56 | 38.0 | 4.20e-01 | 86.8% | 92.9% |
| 3606082 | 650.1.1.1 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › DnaJ | 0.55 | 40.0 | 4.03e-01 | 79.1% | 76.7% |
| 3734009 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 47.0 | 3.06e-01 | 98.9% | 89.7% |
| 3793451 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.54 | 46.0 | 3.84e-01 | 100.0% | 73.1% |
| 5063374 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.54 | 46.0 | 4.10e-01 | 98.9% | 77.0% |
| 3829400 | 6155.1.1.4 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MPC | 0.53 | 40.0 | 3.91e-01 | 83.5% | 77.7% |
| 3251303 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.52 | 39.0 | 4.12e-01 | 80.2% | 96.2% |
| 3682548 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 43.0 | 2.74e-01 | 95.6% | 34.7% |
| 5034944 | 1079.1.1.0 ↗ | alpha complex topology › Transmembrane reductase CcdA › Transmembrane reductase CcdA › Transmembrane reductase CcdA | 0.51 | 40.0 | 3.04e-01 | 90.1% | 88.6% |