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ORF49

Euk-Vir

Macaca_nemestrina_rhadinovirus_2

ORF49__YP_010084595__Macaca_nemestrina_rhadinovirus_2__123630

Identity

Accession:
YP_010084595 ↗
Protein ID:
ORF49
Kingdom:
euk

Quality

89.1 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-67_230-300
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF04793.18 best Herpes_BBRF1 48.7 7.80e-13 52.7% 26.2%
PF04793.18 Herpes_BBRF1 43.0 4.30e-11 43.5% 18.9%
D2 high residues 70-226
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04793.18 best Herpes_BBRF1 139.8 1.40e-40 100.0% 52.8%
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2ip6A00 1.20.1440.140 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.74 41.0 5.51e-01 91.7% 100.0%
5figA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.66 42.0 5.12e-01 99.4% 99.0%
3kavA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.65 41.0 5.01e-01 97.5% 98.0%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.65 30.0 3.35e-01 81.5% 53.1%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.65 45.0 5.18e-01 100.0% 95.7%
4nwpD00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.63 44.0 4.51e-01 100.0% 73.8%
2g2dA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.63 45.0 4.52e-01 100.0% 72.5%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.62 35.0 3.85e-01 84.1% 66.4%
3lmfA00 1.20.1270.360 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.62 42.0 4.97e-01 96.2% 100.0%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.60 41.0 4.78e-01 99.4% 100.0%
3x3bA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.60 48.0 4.04e-01 86.0% 88.6%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.58 38.0 4.11e-01 99.4% 76.3%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.58 35.0 4.25e-01 87.9% 91.2%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 43.0 4.88e-01 96.8% 100.0%
1rtwB00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.56 39.0 3.54e-01 70.1% 80.3%
3c18A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.56 31.0 3.52e-01 86.6% 70.3%
7q37A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 45.0 4.08e-01 86.6% 95.3%
5b2nA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.54 43.0 3.67e-01 85.4% 88.6%
3v5uA02 1.20.1420.30 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › NCX, central ion-binding region 0.54 44.0 3.96e-01 99.4% 62.4%
3d19B00 1.20.1260.120 Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 0.54 47.0 3.99e-01 96.2% 95.4%
1or4B00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.52 37.0 3.70e-01 72.0% 92.4%
4fb2A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.52 47.0 3.53e-01 100.0% 79.6%
1aepA00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.52 39.0 4.00e-01 96.2% 80.4%
6c1qB02 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.52 41.0 3.50e-01 86.6% 92.8%
3emlA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.51 41.0 3.41e-01 85.4% 90.6%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.51 33.0 3.16e-01 100.0% 56.0%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.51 36.0 4.09e-01 89.2% 96.6%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1923803 1120.1.1.1 alpha bundles › KSHV ORF49 protein › KSHV ORF49 protein › KSHV ORF49 protein › Herpes_BBRF1 0.97 90.0 7.08e-01 100.0% 52.5%
2426517 1120.1.1.1 alpha bundles › KSHV ORF49 protein › KSHV ORF49 protein › KSHV ORF49 protein › Herpes_BBRF1 0.88 80.0 6.46e-01 100.0% 54.6%
4020132 633.1.1.0 alpha bundles › Bromodomain-like › Bromodomain › Bromodomain 0.63 38.0 4.12e-01 100.0% 68.9%
4999011 633.18.1.0 alpha bundles › Bromodomain-like › ExoU toxin C-terminal domain › ExoU toxin C-terminal domain 0.62 35.0 4.51e-01 93.6% 98.8%
3389679 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.59 46.0 4.90e-01 100.0% 91.4%
4020994 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.57 33.0 3.50e-01 86.6% 62.1%
3734644 5001.1.1.85 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin 0.57 46.0 3.76e-01 86.6% 87.5%
3402598 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.56 45.0 3.88e-01 86.6% 97.6%
3495555 5079.1.1.0 alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain 0.55 39.0 3.59e-01 73.9% 69.5%
4674738 133.1.1.0 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) 0.55 52.0 4.56e-01 100.0% 76.4%
3830361 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.55 47.0 4.80e-01 98.7% 93.5%
3240670 5001.1.1.35 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srsx 0.53 42.0 3.54e-01 85.4% 89.1%
4024773 633.10.1.0 alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.53 44.0 4.32e-01 88.5% 93.5%
3314513 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.52 48.0 4.76e-01 99.4% 96.9%
3976405 5059.1.1.7 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › DMT_YdcZ 0.51 38.0 3.04e-01 75.2% 96.5%
3171105 174.1.1.60 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF30036 0.51 49.0 4.84e-01 100.0% 98.2%
3612308 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.51 35.0 3.99e-01 95.5% 95.6%
3743961 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.51 42.0 3.94e-01 88.5% 73.3%
5041194 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.51 34.0 3.49e-01 87.3% 69.7%
4610490 1197.1.1.1 alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf 0.50 43.0 3.99e-01 91.7% 91.0%
4675621 140.1.1.11 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 0.50 43.0 3.91e-01 99.4% 69.2%