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ORF49
Euk-VirOvine_gammaherpesvirus_2
ORF49__YP_438172__Ovine_gammaherpesvirus_2__10398
Identity
- Accession:
- YP_438172 ↗
- Protein ID:
- ORF49
- Kingdom:
- euk
Quality
87.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Macavirus›
Ovine_gammaherpesvirus_2
TaxID: 10398
Cluster
View cluster (19 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 90-246
Domain cluster:
rep: BRRF1__YP_010087490__Phascolarctid_gammaherpesvirus_1__2249313__D80-237
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04793.18 best | Herpes_BBRF1 | 56.7 | 2.80e-15 | 100.0% | 52.4% |
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.76 | 50.0 | 5.28e-01 | 100.0% | 73.8% |
| 1wvtA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.67 | 45.0 | 4.61e-01 | 100.0% | 70.9% |
| 6nmnA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.60 | 34.0 | 3.68e-01 | 84.1% | 64.8% |
| 4uiqB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 41.0 | 4.22e-01 | 70.1% | 97.4% |
| 4ivnA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 28.0 | 3.82e-01 | 91.7% | 97.4% |
| 1orsC00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.55 | 31.0 | 3.41e-01 | 86.6% | 65.2% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.55 | 47.0 | 4.81e-01 | 98.1% | 96.6% |
| 6me6B02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 44.0 | 3.68e-01 | 86.6% | 92.9% |
| 2qffA00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.54 | 26.0 | 3.51e-01 | 85.4% | 93.2% |
| 3iq1B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 35.0 | 3.51e-01 | 74.5% | 64.2% |
| 7xv3R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 44.0 | 3.69e-01 | 87.9% | 98.9% |
| 1urvA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 37.0 | 3.74e-01 | 70.1% | 98.7% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.53 | 45.0 | 4.66e-01 | 100.0% | 96.0% |
| 3hyuA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 37.0 | 3.93e-01 | 72.6% | 100.0% |
| 6tblB01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.52 | 33.0 | 3.78e-01 | 80.3% | 88.3% |
| 2kbwA01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.51 | 36.0 | 3.66e-01 | 93.0% | 72.5% |
| 4p9fA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.51 | 36.0 | 3.79e-01 | 85.4% | 79.9% |
| 6dlzA01 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.50 | 47.0 | 4.52e-01 | 100.0% | 98.9% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.50 | 34.0 | 3.97e-01 | 98.1% | 100.0% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1923803 | 1120.1.1.1 ↗ | alpha bundles › KSHV ORF49 protein › KSHV ORF49 protein › KSHV ORF49 protein › Herpes_BBRF1 | 0.93 | 86.0 | 6.77e-01 | 100.0% | 52.5% |
| 2426517 | 1120.1.1.1 ↗ | alpha bundles › KSHV ORF49 protein › KSHV ORF49 protein › KSHV ORF49 protein › Herpes_BBRF1 | 0.88 | 80.0 | 6.45e-01 | 100.0% | 54.6% |
| 4976005 | 601.7.1.34 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › DUF4129 | 0.64 | 35.0 | 4.11e-01 | 84.1% | 76.7% |
| 5010969 | 5069.1.1.105 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF973 | 0.60 | 42.0 | 4.43e-01 | 84.1% | 78.6% |
| 2320846 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.56 | 39.0 | 3.64e-01 | 72.0% | 98.5% |
| 3439705 | 3758.1.1.7 ↗ | alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › BPS1 | 0.55 | 44.0 | 3.95e-01 | 85.4% | 85.5% |
| 4012325 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.55 | 49.0 | 4.23e-01 | 100.0% | 81.2% |
| 3480068 | 174.1.1.32 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Transmemb_17 | 0.54 | 43.0 | 4.36e-01 | 100.0% | 82.4% |
| 5053364 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.54 | 33.0 | 3.65e-01 | 86.6% | 73.8% |
| 3975940 | 601.4.1.6 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain | 0.53 | 47.0 | 4.89e-01 | 100.0% | 98.0% |
| 3829773 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.53 | 43.0 | 3.85e-01 | 87.3% | 72.0% |
| 4311809 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.53 | 43.0 | 3.43e-01 | 87.9% | 88.2% |
| 5078878 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.51 | 41.0 | 4.10e-01 | 96.2% | 80.6% |
| 3920828 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.51 | 36.0 | 2.77e-01 | 70.7% | 87.4% |
| 3637398 | 5001.1.1.85 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Fung_rhodopsin | 0.51 | 41.0 | 3.38e-01 | 86.0% | 59.3% |
| 3233310 | 5057.1.1.1 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb | 0.51 | 33.0 | 3.15e-01 | 89.2% | 53.7% |
| 3588178 | 5067.1.1.22 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › 7TMR-HDED | 0.51 | 34.0 | 3.47e-01 | 84.7% | 67.1% |
D2
medium
residues 22-89
D3
medium
residues 252-324
Domain cluster:
representative
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1k04A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.82 | 70.0 | 6.19e-01 | 93.2% | 88.5% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.77 | 67.0 | 5.51e-01 | 95.9% | 70.0% |
| 1lm3B00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.76 | 63.0 | 5.63e-01 | 93.2% | 77.4% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 65.0 | 5.59e-01 | 97.3% | 79.5% |
| 4xpwA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.74 | 66.0 | 5.41e-01 | 98.6% | 62.6% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.74 | 65.0 | 4.71e-01 | 98.6% | 44.9% |
| 3u9jA00 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.74 | 64.0 | 5.00e-01 | 97.3% | 59.2% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.73 | 62.0 | 5.33e-01 | 94.5% | 76.7% |
| 2j0wA02 | 1.20.120.1320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartokinase, catalytic domain | 0.72 | 61.0 | 5.61e-01 | 91.8% | 86.0% |
| 1cpyA02 | 1.10.287.410 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.70 | 55.0 | 5.59e-01 | 84.9% | 98.6% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.70 | 58.0 | 5.03e-01 | 97.3% | 76.2% |
| 3dyjA02 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.70 | 59.0 | 4.78e-01 | 98.6% | 62.9% |
| 3t46A00 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.69 | 58.0 | 5.77e-01 | 95.9% | 94.7% |
| 2f2gA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.69 | 58.0 | 4.26e-01 | 97.3% | 68.4% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.69 | 57.0 | 4.95e-01 | 95.9% | 85.6% |
| 4i1mB01 | 1.20.120.1700 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.68 | 58.0 | 4.91e-01 | 98.6% | 73.6% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 57.0 | 4.70e-01 | 97.3% | 63.8% |
| 1avoB00 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.66 | 56.0 | 4.61e-01 | 97.3% | 87.9% |
| 7tj9A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.66 | 56.0 | 5.01e-01 | 97.3% | 73.6% |
| 4kjmB01 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.65 | 51.0 | 5.45e-01 | 90.4% | 100.0% |
| 1sf8G00 | 1.20.120.790 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Heat shock protein 90, C-terminal domain | 0.63 | 46.0 | 3.98e-01 | 79.5% | 76.0% |
| 4btfA01 | 1.20.930.20 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain | 0.63 | 53.0 | 4.82e-01 | 95.9% | 81.0% |
| 1siqA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.63 | 53.0 | 4.25e-01 | 97.3% | 64.5% |
| 1v9vA01 | 1.20.1480.20 | Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › MAST3 pre-PK domain-like | 0.61 | 51.0 | 4.77e-01 | 98.6% | 84.2% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.60 | 49.0 | 3.98e-01 | 97.3% | 83.4% |
| 3if8B02 | 1.20.58.730 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 50.0 | 4.61e-01 | 100.0% | 93.0% |
| 3o39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.58 | 44.0 | 3.98e-01 | 78.1% | 82.3% |
| 1pjqA03 | 1.10.8.210 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Sirohaem synthase, dimerisation domain | 0.50 | 39.0 | 4.08e-01 | 90.4% | 93.8% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4483437 | 601.13.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FliS | 0.83 | 72.0 | 5.91e-01 | 95.9% | 56.2% |
| 3254873 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.81 | 71.0 | 6.78e-01 | 95.9% | 89.4% |
| 3495283 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.79 | 69.0 | 5.65e-01 | 97.3% | 72.6% |
| 3222373 | 605.4.1.18 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › PF29357 | 0.78 | 67.0 | 6.44e-01 | 97.3% | 98.8% |
| 3172454 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.78 | 68.0 | 5.48e-01 | 97.3% | 56.4% |
| 4942019 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.78 | 65.0 | 6.37e-01 | 93.2% | 98.8% |
| 3497251 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.78 | 61.0 | 5.95e-01 | 86.3% | 76.2% |
| 3485664 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.78 | 68.0 | 5.60e-01 | 97.3% | 74.6% |
| 3334512 | 601.1.2.103 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PUB2_N | 0.76 | 66.0 | 5.24e-01 | 97.3% | 58.0% |
| 4949658 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.76 | 66.0 | 6.44e-01 | 97.3% | 97.5% |
| 5036629 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.75 | 64.0 | 6.27e-01 | 95.9% | 100.0% |
| 3571743 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.75 | 58.0 | 4.81e-01 | 84.9% | 65.9% |
| 3172902 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.75 | 62.0 | 5.73e-01 | 91.8% | 73.7% |
| 3909550 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.75 | 66.0 | 5.22e-01 | 97.3% | 62.8% |
| 3441901 | 632.1.1.13 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Rx_N | 0.74 | 62.0 | 6.03e-01 | 93.2% | 100.0% |
| 3852296 | 3755.3.1.123 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tektin | 0.74 | 62.0 | 4.73e-01 | 94.5% | 80.0% |
| 3789285 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.74 | 65.0 | 5.18e-01 | 98.6% | 57.9% |
| 5012658 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.73 | 63.0 | 5.92e-01 | 97.3% | 90.0% |
| 5031855 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.73 | 62.0 | 6.09e-01 | 95.9% | 96.2% |
| 3913281 | 3755.3.1.123 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Tektin | 0.73 | 62.0 | 4.91e-01 | 97.3% | 83.7% |
| 5082076 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.72 | 63.0 | 5.51e-01 | 97.3% | 75.5% |
| 4990109 | 633.22.1.1 ↗ | alpha bundles › Bromodomain-like › Vitamin K epoxide reductase (VKOR) › Vitamin K epoxide reductase (VKOR) › VKOR | 0.71 | 60.0 | 5.32e-01 | 94.5% | 100.0% |
| 3646879 | 304.48.1.0 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like | 0.71 | 50.0 | 3.87e-01 | 74.0% | 50.0% |
| 4034431 | 632.15.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › CompInhib_SCIN | 0.70 | 60.0 | 5.81e-01 | 97.3% | 88.1% |
| 2075013 | 601.2.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › 7tm_1,Cytochrom_B562 | 0.70 | 58.0 | 5.59e-01 | 94.5% | 100.0% |
| 3536246 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.70 | 59.0 | 4.81e-01 | 97.3% | 62.8% |
| 4012697 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.70 | 59.0 | 5.80e-01 | 97.3% | 92.5% |
| 3286065 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.69 | 59.0 | 5.99e-01 | 95.9% | 100.0% |
| 3781156 | 109.4.1.70 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CID | 0.69 | 58.0 | 4.23e-01 | 97.3% | 34.9% |
| 4982050 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.68 | 55.0 | 5.63e-01 | 97.3% | 98.6% |
| 3488482 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.67 | 54.0 | 4.21e-01 | 89.0% | 70.9% |
| 4937380 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.67 | 52.0 | 5.19e-01 | 86.3% | 100.0% |
| 4020288 | 109.4.1.108 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CTNNBL | 0.64 | 48.0 | 2.87e-01 | 80.8% | 21.6% |
| 59853 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 48.0 | 3.32e-01 | 80.8% | 29.4% |
| 4569 | 109.4.1.290 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PrgX_C_TPR | 0.63 | 48.0 | 3.32e-01 | 80.8% | 29.9% |
| 4971141 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 47.0 | 3.39e-01 | 82.2% | 45.9% |
| 3271624 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.58 | 47.0 | 2.95e-01 | 90.4% | 82.8% |