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ORF50

Euk-Vir

Callitrichine_gammaherpesvirus_3

ORF50__NP_733904__Callitrichine_gammaherpesvirus_3__106331

Identity

Accession:: NP_733904 ↗
Protein ID:: ORF50
Kingdom:: euk

Quality

88.2 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Lymphocryptovirus› callitrichine_gammaherpesvirus_3

TaxID: 106331

Cluster

View cluster (58 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 503-697

PDB

Domain cluster: rep: primase__YP_009345453__Noumeavirus__1955558__D12-194

D2 high residues 714-837

PDB

Domain cluster: rep: helicase-primase_primase_subunit__NP_944382__Psittacid_alphaherpesvirus_1__50294__D1138-1286

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03121.21 best	Herpes_UL52	81.1	5.80e-23	59.7%	98.7%

D3 medium residues 1-152

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_010085930__Wood_mouse_herpesvirus__432370__D12-162

D4 medium residues 153-234

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_401662__Human_gammaherpesvirus_4__10376__D153-223

D5 medium residues 235-330

PDB

Domain cluster: rep: ORF56__YP_001129409__Human_gammaherpesvirus_8__37296__D254-341

CATH (13)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3f4sA02	1.10.40.80	Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 ›	0.63	37.0	4.37e-01	81.2%	87.5%
1xrhD01	1.10.1530.10	Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel	0.58	37.0	3.69e-01	93.8%	59.2%
2ex3B02	1.20.1270.230	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › DNA terminal protein Gp3, priming domain	0.57	39.0	4.20e-01	99.0%	84.0%
2rd3D00	1.20.910.10	Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like	0.56	47.0	3.68e-01	94.8%	100.0%
3ejnA03	1.20.120.840	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SusD-like, tetratrico peptide repeats domain	0.55	41.0	3.95e-01	87.5%	67.6%
3nynA03	1.10.167.10	Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2	0.55	33.0	3.52e-01	85.4%	67.9%
3ddhA02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.54	36.0	3.85e-01	84.4%	81.5%
3ay5A01	1.20.1420.10	Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain	0.54	45.0	4.11e-01	94.8%	69.2%
1ywfA00	3.90.190.10	Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily	0.52	43.0	3.22e-01	90.6%	76.8%
4lqxA00	1.20.910.10	Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like	0.51	43.0	3.17e-01	97.9%	57.4%
2yfaA02	1.20.1440.210	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) ›	0.51	42.0	3.96e-01	89.6%	75.9%
3ezhA00	1.20.120.960	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain	0.51	40.0	3.87e-01	95.8%	73.7%
3hl6A02	1.20.58.700	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.50	35.0	3.31e-01	93.8%	59.1%

ECOD (9)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4031490	632.2.1.5 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › DUF1542	0.65	45.0	4.92e-01	76.0%	92.0%
3166682	101.1.10.0 ↗	alpha arrays › HTH › HTH › Cyclin-like	0.64	40.0	3.96e-01	86.5%	59.0%
4259224	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.58	41.0	3.50e-01	71.9%	87.7%
4932992	604.39.1.0 ↗	alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters	0.58	43.0	3.34e-01	79.2%	63.6%
3644932	5069.1.3.62 ↗	alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Mito_carr	0.54	44.0	4.08e-01	89.6%	75.2%
3641365	309.1.1.11 ↗	a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PqqF-like_C_4	0.53	44.0	3.29e-01	90.6%	66.5%
3435097	4177.1.1.11 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › DUF632	0.53	43.0	3.23e-01	91.7%	77.7%
3880538	632.1.1.28 ↗	alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › DUF2678	0.52	42.0	4.38e-01	90.6%	100.0%
3416059	148.1.1.25 ↗	alpha arrays › Histone-like › Histone-related › Histone › Tim17	0.51	38.0	3.34e-01	80.2%	69.7%

D6 medium residues 390-502

PDB

Domain cluster: representative

CATH (3)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3tm8B00	1.10.3210.10	Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432	0.52	39.0	2.88e-01	78.8%	58.3%
4kx7A03	2.60.40.1910	Mainly Beta › Sandwich › Immunoglobulin-like ›	0.51	24.0	2.74e-01	74.3%	58.3%
2jxtA01	3.10.20.10	Alpha Beta › Roll › Ubiquitin-like (UB roll) ›	0.50	26.0	3.16e-01	71.7%	75.0%

ECOD (5)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3363778	390.1.1.0 ↗	few secondary structure elements › Hairpin loop containing domain-like › Hairpin loop containing domain-like › Hairpin loop containing domain-like	0.65	29.0	3.93e-01	96.5%	83.6%
3388590	379.1.1.0 ↗	few secondary structure elements › Kazal-type serine protease inhibitors-like › Kazal-type serine protease inhibitors › Kazal-type serine protease inhibitors	0.64	28.0	3.77e-01	70.8%	76.7%
3414064	379.1.1.0 ↗	few secondary structure elements › Kazal-type serine protease inhibitors-like › Kazal-type serine protease inhibitors › Kazal-type serine protease inhibitors	0.56	26.0	3.44e-01	72.6%	85.5%
4939739	3115.1.1.1 ↗	a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A	0.53	27.0	3.70e-01	71.7%	96.6%
5000510	3115.1.1.1 ↗	a+b two layers › GP2-like › RplX-like › RplX-like › Ribosomal_L18A	0.51	27.0	3.24e-01	71.7%	76.0%