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ORF56

Euk-Vir

Ovine_gammaherpesvirus_2

ORF56__YP_438180__Ovine_gammaherpesvirus_2__10398

Identity

Accession:: YP_438180 ↗
Protein ID:: ORF56
Kingdom:: euk

Quality

87.8 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Macavirus› Ovine_gammaherpesvirus_2

TaxID: 10398

Cluster

View cluster (58 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-143

PDB

Domain cluster: rep: helicase-primase_primase_subunit__YP_010085930__Wood_mouse_herpesvirus__432370__D12-162

D2 high residues 339-419

PDB

Domain cluster: rep: ORF56__YP_001129409__Human_gammaherpesvirus_8__37296__D349-421

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1rxtC02	3.40.630.30	Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT)	0.50	40.0	3.16e-01	91.4%	77.7%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3803343	193.1.1.1 ↗	alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like › CH	0.65	47.0	4.15e-01	75.3%	79.1%
5078149	2006.1.4.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN	0.52	34.0	3.00e-01	100.0%	41.5%
4952353	2004.1.1.49 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › UvrD-helicase	0.51	42.0	2.51e-01	96.3%	65.5%

D3 high residues 710-836

PDB

Domain cluster: rep: helicase-primase_primase_subunit__NP_944382__Psittacid_alphaherpesvirus_1__50294__D1138-1286

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF03121.21 best	Herpes_UL52	96.6	8.70e-28	59.1%	98.7%

D4 medium residues 175-253

PDB

Domain cluster: representative

CATH (8)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5y27A00	1.10.20.10	Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A	0.66	48.0	4.45e-01	96.2%	61.2%
3sdeA03	6.10.250.1170	Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.64	43.0	4.48e-01	74.7%	73.3%
4aflA00	6.10.140.1740	Special › Helix non-globular › Helix Hairpins ›	0.60	48.0	4.40e-01	86.1%	68.6%
7po9A01	3.40.1800.20	Alpha Beta › 3-Layer(aba) Sandwich › His-Me finger endonuclease fold ›	0.60	44.0	4.34e-01	100.0%	72.1%
6jgwA01	1.10.1660.10	Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 ›	0.58	48.0	4.19e-01	93.7%	59.5%
1af8A00	1.10.1200.10	Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like	0.56	37.0	3.64e-01	70.9%	62.8%
3kzxA02	1.10.150.730	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 ›	0.53	38.0	4.17e-01	79.7%	95.2%
3ftdA02	1.10.8.100	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › rRNA adenine dimethylase, C-terminal domain	0.50	36.0	4.04e-01	74.7%	96.8%

ECOD (8)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3488651	7023.1.1.0 ↗	alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein	0.67	41.0	3.91e-01	94.9%	53.3%
4682191	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.61	55.0	3.85e-01	100.0%	89.1%
5039161	5058.1.1.0 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region	0.60	40.0	4.00e-01	84.8%	65.5%
2103762	148.1.3.19 ↗	alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_3	0.56	30.0	3.40e-01	77.2%	68.3%
55509	132.1.1.0 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP)	0.56	37.0	3.66e-01	70.9%	63.5%
3223612	101.1.17.0 ↗	alpha arrays › HTH › HTH › FF domain	0.55	31.0	3.26e-01	79.7%	61.4%
137564	2006.1.1.18 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › HAD_2	0.52	41.0	3.08e-01	86.1%	50.0%
3788457	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.51	42.0	2.85e-01	88.6%	31.9%

D5 medium residues 254-313

PDB

Domain cluster: representative

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3662839	172.2.1.1 ↗	alpha complex topology › Citrate synthase-like › Urease accessory protein ureF › Urease accessory protein ureF › UreF	0.60	50.0	3.43e-01	96.7%	79.1%
2172020	3317.1.1.1 ↗	alpha arrays › KorB C-terminal domain-like › KorB C-terminal domain › KorB C-terminal domain › ParB	0.56	43.0	4.01e-01	85.0%	66.7%
4335237	2007.1.19.4 ↗	a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › FabD/lysophospholipase-like › SAT	0.52	41.0	2.74e-01	96.7%	18.7%

D6 medium residues 433-488

PDB

Domain cluster: rep: ORF56__YP_001129409__Human_gammaherpesvirus_8__37296__D437-488

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4272481	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.57	34.0	3.10e-01	75.0%	41.2%
3944365	132.1.1.1 ↗	alpha bundles › ACP-like › Acyl-carrier protein (ACP) › Acyl-carrier protein (ACP) › PP-binding	0.56	36.0	3.18e-01	78.6%	42.2%
4208895	3681.1.1.0 ↗	a+b complex topology › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit › Helical hairpin insertion in E. coli DNA-directed RNA polymerase beta subunit	0.51	36.0	3.10e-01	78.6%	75.0%

D7 medium residues 489-548_564-704

PDB

Domain cluster: rep: primase__YP_009345453__Noumeavirus__1955558__D12-194