←Back to structures
ORF57
Euk-VirHuman_gammaherpesvirus_8
ORF57__YP_001129410__Human_gammaherpesvirus_8__37296
Identity
- Accession:
- YP_001129410 ↗
- Protein ID:
- ORF57
- Kingdom:
- euk
Quality
74.8
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Rhadinovirus›
Human_gammaherpesvirus_8
TaxID: 37296
Cluster
View cluster (20 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 221-304
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05459.19 best | Herpes_UL69 | 54.7 | 1.50e-14 | 82.1% | 30.4% |
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1iurA01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.60 | 42.0 | 4.74e-01 | 78.6% | 100.0% |
| 3tixA02 | 6.10.140.1690 | Special › Helix non-globular › Helix Hairpins › | 0.54 | 40.0 | 4.15e-01 | 77.4% | 97.5% |
| 1wz8A01 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.54 | 48.0 | 3.63e-01 | 100.0% | 73.3% |
| 1rrzA00 | 1.20.970.20 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Glycogen synthesis protein GlgS | 0.53 | 36.0 | 3.92e-01 | 76.2% | 87.9% |
D2
medium
residues 305-443
Domain cluster:
rep: transcriptional_control_protein__NP_065556__Alcelaphine_gammaherpesvirus_1__35252__D306-423
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05459.19 best | Herpes_UL69 | 104.1 | 1.20e-29 | 100.0% | 62.6% |
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3zsuA00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.63 | 38.0 | 4.14e-01 | 86.3% | 71.2% |
| 1yo7A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 42.0 | 4.53e-01 | 98.6% | 87.5% |
| 4f7aA00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.58 | 43.0 | 2.99e-01 | 77.7% | 42.4% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 42.0 | 3.78e-01 | 77.0% | 88.5% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.56 | 40.0 | 4.34e-01 | 98.6% | 87.9% |
| 7zcvA02 | 1.25.40.400 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 41.0 | 3.58e-01 | 75.5% | 62.4% |
| 4hkrA00 | 1.20.140.140 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai | 0.56 | 39.0 | 3.67e-01 | 89.2% | 59.4% |
| 4ezbA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.55 | 34.0 | 3.72e-01 | 78.4% | 73.5% |
| 3qsgA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.55 | 35.0 | 3.84e-01 | 78.4% | 77.4% |
| 8anqA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 44.0 | 3.74e-01 | 100.0% | 52.7% |
| 3ez0C00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 38.0 | 3.34e-01 | 75.5% | 95.2% |
| 3snxA00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 41.0 | 2.84e-01 | 82.7% | 73.2% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 45.0 | 4.16e-01 | 100.0% | 74.9% |
| 2uyyA02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.51 | 36.0 | 3.79e-01 | 81.3% | 81.3% |
| 1jwnA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.50 | 43.0 | 4.25e-01 | 92.1% | 93.1% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 40.0 | 3.93e-01 | 97.1% | 77.1% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2390527 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.99 | 97.0 | 7.33e-01 | 100.0% | 49.6% |
| 2418879 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.90 | 87.0 | 6.70e-01 | 100.0% | 51.6% |
| 3820110 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.56 | 44.0 | 4.48e-01 | 99.3% | 83.6% |
| 3668980 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.56 | 46.0 | 4.69e-01 | 98.6% | 90.4% |
| 3417891 | 633.21.1.18 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CASP_dom | 0.54 | 45.0 | 4.35e-01 | 100.0% | 80.5% |
| 3871867 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.54 | 36.0 | 3.63e-01 | 87.1% | 67.1% |
| 3630515 | 604.1.1.174 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TRC8_N | 0.53 | 39.0 | 3.32e-01 | 77.0% | 67.9% |
| 3345521 | 109.4.1.1403 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_TBCD, ARM_TBCD_2nd | 0.52 | 37.0 | 2.49e-01 | 72.7% | 34.4% |
| 3613499 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.52 | 40.0 | 3.81e-01 | 79.9% | 88.5% |
| 3351501 | 611.7.1.2 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain › MCAfunc | 0.52 | 41.0 | 4.05e-01 | 100.0% | 79.3% |
| 3783655 | 633.21.1.10 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › MARVEL | 0.51 | 43.0 | 4.24e-01 | 95.7% | 86.2% |
| 4027495 | 109.4.1.68 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Coatomer_E | 0.51 | 41.0 | 3.32e-01 | 85.6% | 68.5% |
| 4977275 | 604.1.1.268 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF5658 | 0.51 | 32.0 | 3.48e-01 | 81.3% | 76.4% |
| 4944583 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.51 | 39.0 | 3.61e-01 | 97.8% | 61.6% |
| 3994104 | 109.4.1.418 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Condensin2nSMC | 0.51 | 38.0 | 2.82e-01 | 78.4% | 42.9% |
| 3917561 | 109.4.1.395 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fanconi_C | 0.51 | 36.0 | 2.62e-01 | 73.4% | 73.4% |
| 4985462 | 192.2.1.89 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › DUF7121 | 0.51 | 34.0 | 2.85e-01 | 93.5% | 38.3% |