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ORF57
Euk-VirFelis_catus_gammaherpesvirus_1
ORF57__YP_009173936__Felis_catus_gammaherpesvirus_1__1452540
Identity
- Accession:
- YP_009173936 ↗
- Protein ID:
- ORF57
- Kingdom:
- euk
Quality
65.9
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Percavirus›
Felid_gammaherpesvirus_1
TaxID: 1452540
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 224-359
Domain cluster:
rep: ORF57__YP_010084605__Macaca_nemestrina_rhadinovirus_2__123630__D216-320_435-447
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05459.19 best | Herpes_UL69 | 77.9 | 1.20e-21 | 67.7% | 42.1% |
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4b89A00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 50.0 | 4.24e-01 | 89.0% | 87.4% |
| 8sorA01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.59 | 54.0 | 3.99e-01 | 100.0% | 56.8% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 49.0 | 4.41e-01 | 92.6% | 84.9% |
| 4qndA00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.56 | 38.0 | 4.36e-01 | 96.3% | 96.9% |
| 5dikA00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.53 | 37.0 | 4.01e-01 | 79.4% | 87.5% |
| 5nohA00 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.53 | 26.0 | 2.99e-01 | 87.5% | 61.2% |
| 1lk3A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.51 | 31.0 | 3.13e-01 | 81.6% | 57.4% |
| 4jgwA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.51 | 43.0 | 4.18e-01 | 95.6% | 87.8% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.50 | 41.0 | 3.64e-01 | 89.0% | 75.4% |
ECOD (21)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2390527 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.94 | 80.0 | 6.05e-01 | 87.5% | 42.9% |
| 2418879 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.93 | 79.0 | 6.02e-01 | 87.5% | 44.3% |
| 1562404 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.85 | 73.0 | 5.67e-01 | 89.7% | 45.1% |
| 3339492 | 109.4.1.1191 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ARM_LIN_C | 0.65 | 59.0 | 4.08e-01 | 99.3% | 52.3% |
| 3397045 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 45.0 | 4.44e-01 | 70.6% | 83.4% |
| 3582621 | 109.4.1.299 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Ltn1_1st | 0.63 | 54.0 | 4.30e-01 | 93.4% | 80.0% |
| 3513983 | 109.25.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN | 0.63 | 47.0 | 4.94e-01 | 79.4% | 100.0% |
| 3594783 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 55.0 | 3.51e-01 | 97.8% | 25.5% |
| 3350101 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.61 | 49.0 | 4.81e-01 | 83.8% | 89.0% |
| 3905477 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 54.0 | 3.46e-01 | 98.5% | 24.1% |
| 3629112 | 109.4.1.1446 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RRP12_HEAT, HEAT_RRP12_N | 0.60 | 55.0 | 3.26e-01 | 100.0% | 21.8% |
| 3204527 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.60 | 54.0 | 3.75e-01 | 100.0% | 91.1% |
| 3644609 | 109.4.1.2210 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30701 | 0.59 | 53.0 | 3.76e-01 | 100.0% | 37.6% |
| 4596370 | 109.4.1.115 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Peptidase_M9_N | 0.58 | 51.0 | 4.05e-01 | 98.5% | 62.8% |
| 3601961 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 47.0 | 4.98e-01 | 98.5% | 100.0% |
| 3771203 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 50.0 | 3.82e-01 | 99.3% | 61.6% |
| 3685269 | 109.4.1.681 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 | 0.55 | 48.0 | 4.45e-01 | 95.6% | 94.9% |
| 4029195 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.55 | 50.0 | 4.09e-01 | 100.0% | 66.4% |
| 2067093 | 186.2.1.1 ↗ | alpha arrays › lambda integrase-N-like › VEFS domain › VEFS domain › VEFS-Box | 0.54 | 40.0 | 4.07e-01 | 80.1% | 77.4% |
| 5075376 | 109.4.1.158 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ERAP1_C | 0.53 | 45.0 | 3.47e-01 | 91.9% | 75.1% |
| 3236861 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.50 | 35.0 | 3.34e-01 | 70.6% | 83.7% |
D2
medium
residues 360-471
Domain cluster:
rep: transcriptional_control_protein__NP_065556__Alcelaphine_gammaherpesvirus_1__35252__D306-423
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF05459.19 best | Herpes_UL69 | 56.2 | 5.40e-15 | 100.0% | 50.5% |
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7mqzA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.68 | 45.0 | 3.63e-01 | 75.0% | 35.9% |
| 1dlcA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.68 | 53.0 | 4.19e-01 | 83.0% | 77.7% |
| 4gywA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.67 | 43.0 | 4.47e-01 | 73.2% | 68.6% |
| 4xi0F00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.67 | 44.0 | 3.78e-01 | 71.4% | 42.1% |
| 2r5sA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 42.0 | 4.62e-01 | 71.4% | 86.4% |
| 4ga0A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 44.0 | 4.08e-01 | 73.2% | 67.8% |
| 4rg9B01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 47.0 | 4.11e-01 | 80.4% | 63.5% |
| 4gpkF02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 45.0 | 3.57e-01 | 79.5% | 61.7% |
| 4nq0A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 44.0 | 3.43e-01 | 76.8% | 72.4% |
| 4b0zA00 | 1.25.40.990 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 44.0 | 3.52e-01 | 77.7% | 54.6% |
| 1rv2D04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.59 | 26.0 | 3.24e-01 | 86.6% | 64.3% |
| 2dbaA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.58 | 42.0 | 4.14e-01 | 75.9% | 86.4% |
| 3as5A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 43.0 | 3.66e-01 | 79.5% | 52.2% |
| 5an3A01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 47.0 | 4.51e-01 | 92.0% | 90.7% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.55 | 39.0 | 3.82e-01 | 73.2% | 76.0% |
| 3bqoA00 | 1.25.40.210 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Telomere repeat-binding factor, dimerisation domain | 0.54 | 43.0 | 3.58e-01 | 93.8% | 48.0% |
| 2b1eA04 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.53 | 37.0 | 3.58e-01 | 71.4% | 76.4% |
| 3vadA01 | 1.20.140.20 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain | 0.53 | 39.0 | 3.48e-01 | 100.0% | 54.5% |
| 3zbhA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.51 | 29.0 | 3.23e-01 | 87.5% | 70.0% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2390527 | 3977.1.1.1 ↗ | alpha duplicates or obligate multimers › ICP27 homology domain › ICP27 homology domain › ICP27 homology domain › Herpes_UL69 | 0.89 | 85.0 | 6.08e-01 | 100.0% | 39.6% |
| 3174383 | 109.24.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in dedicator of cytokinesis protein 9 › Helical domain in dedicator of cytokinesis protein 9 › DHR-2_Lobe_C | 0.66 | 48.0 | 4.35e-01 | 75.0% | 86.7% |
| 4008559 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.66 | 47.0 | 3.37e-01 | 74.1% | 32.4% |
| 3886845 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.63 | 46.0 | 3.74e-01 | 76.8% | 60.0% |
| 3305420 | 109.4.1.202 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_16 | 0.61 | 44.0 | 4.01e-01 | 74.1% | 72.0% |
| 3316271 | 109.4.1.189 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_2 | 0.61 | 44.0 | 3.70e-01 | 75.9% | 75.9% |
| 3680491 | 109.25.1.11 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › DUF4220 | 0.60 | 52.0 | 3.91e-01 | 94.6% | 73.1% |
| 3302280 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.59 | 43.0 | 2.96e-01 | 75.9% | 33.8% |
| 3599624 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 47.0 | 2.94e-01 | 83.9% | 52.2% |
| 3526587 | 109.4.1.839 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Maestro_HEAT | 0.57 | 49.0 | 3.43e-01 | 93.8% | 53.4% |
| 3671587 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.55 | 41.0 | 3.56e-01 | 77.7% | 56.5% |
| 5009902 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.55 | 39.0 | 3.61e-01 | 72.3% | 92.1% |
| 3197498 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 40.0 | 3.62e-01 | 78.6% | 78.8% |
| 3595031 | 109.4.1.1312 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF30475 | 0.54 | 49.0 | 3.54e-01 | 99.1% | 42.2% |
| 3842806 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 38.0 | 3.58e-01 | 74.1% | 64.4% |
| 3833310 | 109.4.1.883 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR+PPR_2 | 0.53 | 39.0 | 4.11e-01 | 77.7% | 95.0% |
| 4027843 | 109.46.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Helical domain in TOPLESS related protein 2 (TPR2) › Helical domain in TOPLESS related protein 2 (TPR2) | 0.51 | 37.0 | 3.66e-01 | 76.8% | 100.0% |
| 3659459 | 109.4.1.109 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 | 0.51 | 46.0 | 3.21e-01 | 99.1% | 80.8% |
| 3785103 | 1065.1.1.1 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain › SPX | 0.50 | 43.0 | 3.57e-01 | 97.3% | 91.6% |