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ORF63
Euk-VirFelis_catus_gammaherpesvirus_1
ORF63__YP_009173943__Felis_catus_gammaherpesvirus_1__1452540
Identity
- Accession:
- YP_009173943 ↗
- Protein ID:
- ORF63
- Kingdom:
- euk
Quality
80.3
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Percavirus›
Felid_gammaherpesvirus_1
TaxID: 1452540
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-172
Domain cluster:
rep: tegument_protein__YP_010087505__Phascolarctid_gammaherpesvirus_1__2249313__D1-176
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 107.4 | 8.50e-31 | 98.3% | 18.7% |
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5cwhA01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.65 | 44.0 | 4.61e-01 | 76.7% | 75.0% |
| 6whbA01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.61 | 47.0 | 4.05e-01 | 94.2% | 50.5% |
| 5cwkA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 42.0 | 4.31e-01 | 75.6% | 75.6% |
| 3q5wA00 | 1.20.58.1590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tethering factor for nuclear proteasome Cut8/Sts1 | 0.58 | 43.0 | 4.08e-01 | 76.2% | 71.7% |
| 3onkA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.56 | 42.0 | 4.65e-01 | 93.0% | 99.3% |
| 3p1uA00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 47.0 | 3.44e-01 | 96.5% | 86.4% |
| 7ldgA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.51 | 41.0 | 3.78e-01 | 85.5% | 70.5% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2098130 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.79 | 74.0 | 6.21e-01 | 100.0% | 77.8% |
| 3443502 | 109.4.1.541 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4220 | 0.61 | 52.0 | 4.52e-01 | 94.8% | 89.6% |
| 3927275 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 42.0 | 4.31e-01 | 76.2% | 75.3% |
| 3727071 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 41.0 | 3.09e-01 | 72.7% | 39.1% |
| 3628587 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 46.0 | 3.85e-01 | 85.5% | 56.6% |
| 3917650 | 3965.1.1.1 ↗ | alpha arrays › Origin recognition complex subunit 3 helical insert domain › Origin recognition complex subunit 3 helical insert domain › Origin recognition complex subunit 3 helical insert domain › ORC3_ins | 0.57 | 36.0 | 3.46e-01 | 89.0% | 53.2% |
| 4027953 | 109.4.1.85 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nop52 | 0.56 | 46.0 | 3.91e-01 | 85.5% | 63.6% |
| 4020513 | 109.4.1.447 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PI4K_N | 0.56 | 45.0 | 3.60e-01 | 85.5% | 57.4% |
| 3201888 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 45.0 | 4.01e-01 | 85.5% | 66.7% |
| 3286283 | 4266.2.1.1 ↗ | alpha bundles › Hyaluronidase domain-like › TTHA0068-like › TTHA0068-like › DUF309 | 0.55 | 33.0 | 4.07e-01 | 72.1% | 95.2% |
| 3506420 | 109.4.1.1550 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TFCD_C, ARM_TBCD, ARM_TBCD_2nd | 0.54 | 48.0 | 3.12e-01 | 97.7% | 22.7% |
| 3637886 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 40.0 | 4.00e-01 | 79.7% | 81.7% |
| 3964363 | 1051.1.1.0 ↗ | alpha superhelices › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain › Putative 3-oxoacyl-(acyl-carrier-protein) synthase N-terminal domain | 0.53 | 28.0 | 3.59e-01 | 86.6% | 90.5% |
D2
medium
residues 173-308
Domain cluster:
rep: orf63__YP_009044446__Alcelaphine_gammaherpesvirus_2__138184__D216-316
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 99.2 | 2.50e-28 | 97.8% | 14.3% |
D3
medium
residues 309-453
Domain cluster:
rep: JM123__YP_238426__Macaca_fuscata_rhadinovirus__272551__D339-466
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 69.4 | 2.50e-19 | 99.3% | 16.9% |
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3e7qA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 45.0 | 4.01e-01 | 70.3% | 91.3% |
| 2hytA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 46.0 | 4.20e-01 | 75.9% | 96.4% |
| 1o5hA00 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.62 | 46.0 | 4.15e-01 | 77.9% | 69.0% |
| 5mi7A03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.61 | 54.0 | 4.44e-01 | 96.6% | 61.0% |
| 5tqbB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 43.0 | 3.31e-01 | 74.5% | 42.8% |
| 3ug9A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 43.0 | 3.77e-01 | 82.1% | 58.7% |
| 4nq0A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 40.0 | 3.38e-01 | 89.7% | 43.7% |
| 4flbA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 35.0 | 3.73e-01 | 91.0% | 74.8% |
| 1sz9C00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 35.0 | 3.62e-01 | 93.1% | 72.1% |
| 3bqyA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 39.0 | 3.89e-01 | 78.6% | 98.7% |
| 2a2fX02 | 1.20.58.670 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain D | 0.51 | 42.0 | 4.43e-01 | 95.2% | 99.2% |
| 2onkC00 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.51 | 40.0 | 3.29e-01 | 80.7% | 71.4% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.51 | 42.0 | 3.25e-01 | 88.3% | 88.3% |
| 2gnxA01 | 1.10.3450.30 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › | 0.50 | 43.0 | 4.05e-01 | 93.8% | 78.2% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1283715 | 3852.1.1.1 ↗ | alpha superhelices › UL37 N-terminal half › UL37 N-terminal half › UL37 N-terminal half › Herpes_UL37_1 | 0.82 | 68.0 | 4.62e-01 | 100.0% | 26.3% |
| 3227322 | 5001.1.1.63 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab | 0.66 | 50.0 | 3.91e-01 | 79.3% | 78.8% |
| 3239549 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.65 | 50.0 | 4.05e-01 | 82.1% | 80.4% |
| 3681785 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.63 | 47.0 | 4.38e-01 | 77.2% | 81.1% |
| 3600233 | 3914.1.1.0 ↗ | alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain | 0.63 | 47.0 | 3.18e-01 | 77.9% | 87.0% |
| 3244449 | 3755.3.1.408 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Zw10_N | 0.59 | 53.0 | 4.96e-01 | 100.0% | 88.9% |
| 3521246 | 109.4.1.1286 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12 | 0.59 | 40.0 | 4.08e-01 | 85.5% | 71.4% |
| 5024802 | 3543.1.1.14 ↗ | alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › DUF981 | 0.58 | 51.0 | 4.71e-01 | 96.6% | 77.8% |
| 3174418 | 133.1.1.7 ↗ | alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › PF28625 | 0.58 | 41.0 | 3.93e-01 | 71.7% | 67.1% |
| 3237210 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.57 | 40.0 | 3.56e-01 | 71.7% | 80.9% |
| 3786622 | 109.4.1.682 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RasGEF_N | 0.57 | 40.0 | 3.41e-01 | 72.4% | 62.5% |
| 5041759 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.57 | 45.0 | 3.92e-01 | 83.4% | 88.1% |
| 3172226 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.56 | 40.0 | 3.36e-01 | 73.8% | 91.2% |
| 3898385 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 40.0 | 4.00e-01 | 100.0% | 71.3% |
| 3232473 | 603.1.1.97 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE | 0.54 | 41.0 | 3.54e-01 | 80.0% | 79.6% |
| 3694455 | 5001.1.1.28 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Per1 | 0.54 | 40.0 | 3.11e-01 | 81.4% | 36.4% |
| None | — | 0.53 | 43.0 | 3.79e-01 | 84.8% | 78.5% | |
| 3257704 | 5001.1.1.265 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_2, PF29575 | 0.52 | 40.0 | 3.07e-01 | 80.0% | 46.3% |
| 3442551 | 109.4.1.63 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TAP42 | 0.52 | 47.0 | 3.79e-01 | 100.0% | 78.6% |
| 3453708 | 109.4.1.541 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4220 | 0.51 | 46.0 | 3.89e-01 | 100.0% | 67.3% |
D4
medium
residues 488-633
Domain cluster:
rep: JM123__YP_238426__Macaca_fuscata_rhadinovirus__272551__D499-654
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 137.8 | 5.40e-40 | 100.0% | 15.6% |
D5
medium
residues 634-808_840-860
Domain cluster:
rep: ORF63__YP_010084430__Retroperitoneal_fibromatosis-associated_herpesvirus__111469__D640-805
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04523.19 best | Herpes_U30 | 135.7 | 2.30e-39 | 96.9% | 19.6% |