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ORF63

Euk-Vir

Retroperitoneal_fibromatosis-associated_herpesvirus

ORF63__YP_010084430__Retroperitoneal_fibromatosis-associated_herpesvirus__111469

Identity

Accession:
YP_010084430 ↗
Protein ID:
ORF63
Kingdom:
euk

Quality

78.7 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Rhadinovirus› Retroperitoneal_fibromatosis-associated_herpesvirus

TaxID: 111469

Cluster

View cluster (39 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 11-180
PDB
Domain cluster: rep: tegument_protein__YP_010087505__Phascolarctid_gammaherpesvirus_1__2249313__D1-176
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04523.19 best Herpes_U30 97.1 1.10e-27 99.4% 18.4%
D2 high residues 509-639
PDB
Domain cluster: rep: JM123__YP_238426__Macaca_fuscata_rhadinovirus__272551__D499-654
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04523.19 best Herpes_U30 142.9 1.50e-41 100.0% 14.2%
D3 medium residues 187-209_304-357_383-454
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF04523.19 best Herpes_U30 48.3 6.10e-13 49.0% 8.9%
PF04523.19 Herpes_U30 37.2 1.40e-09 45.0% 6.8%
CATH (10)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7w9wA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.60 46.0 3.87e-01 81.9% 67.2%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 41.0 4.78e-01 75.8% 98.2%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.58 40.0 4.70e-01 75.8% 97.2%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 41.0 4.74e-01 80.5% 100.0%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 28.0 2.78e-01 71.1% 42.2%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 38.0 4.53e-01 79.9% 100.0%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 39.0 4.59e-01 82.6% 99.1%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 38.0 4.37e-01 82.6% 99.1%
1jr8A00 1.20.120.310 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain 0.52 34.0 3.99e-01 72.5% 93.3%
5j1hA01 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 40.0 3.81e-01 83.9% 91.2%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3373206 3684.1.1.0 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.62 44.0 3.42e-01 72.5% 66.9%
3901313 601.1.2.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.58 44.0 4.38e-01 79.2% 98.1%
4027056 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.58 41.0 4.29e-01 72.5% 92.9%
3574755 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.58 42.0 4.86e-01 83.2% 100.0%
4974646 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 38.0 4.40e-01 70.5% 96.2%
3796046 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.57 39.0 4.49e-01 81.2% 91.3%
3521044 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 41.0 4.72e-01 82.6% 99.1%
3894911 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.57 40.0 4.66e-01 83.2% 98.2%
3758972 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.57 40.0 4.67e-01 82.6% 98.2%
3541655 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.57 40.0 4.47e-01 81.9% 90.0%
4013499 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.57 40.0 3.91e-01 71.8% 84.4%
3559937 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.56 38.0 4.54e-01 80.5% 100.0%
3900921 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.55 38.0 4.18e-01 81.2% 86.7%
3240501 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.55 39.0 4.06e-01 83.2% 77.9%
3887313 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.55 40.0 4.54e-01 83.9% 98.3%
3894879 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.54 37.0 4.40e-01 81.9% 100.0%
3894917 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.53 39.0 4.26e-01 82.6% 92.5%
3400732 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.53 37.0 4.14e-01 82.6% 90.0%
4091932 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 40.0 4.24e-01 79.9% 100.0%
3750020 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.52 36.0 4.18e-01 79.9% 100.0%
3801230 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 36.0 3.22e-01 70.5% 70.2%
3484910 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.51 40.0 4.47e-01 80.5% 100.0%
3566007 604.1.1.1 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.50 37.0 4.23e-01 96.0% 100.0%
3600424 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 44.0 3.03e-01 95.3% 44.3%
D4 medium residues 640-805
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04523.19 best Herpes_U30 83.9 1.10e-23 100.0% 18.2%
CATH (54)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.82 49.0 6.21e-01 93.4% 98.0%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 57.0 6.61e-01 97.0% 97.5%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.77 55.0 4.97e-01 72.3% 68.4%
1hciA03 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 54.0 6.20e-01 97.0% 100.0%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.75 58.0 5.87e-01 96.4% 81.6%
2kbbA00 1.20.1420.10 Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain 0.75 44.0 4.34e-01 93.4% 54.6%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 53.0 6.08e-01 94.0% 100.0%
2nrjA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.74 69.0 5.41e-01 100.0% 72.7%
1hciA04 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 49.0 5.80e-01 97.0% 98.2%
7nmqA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.73 69.0 5.28e-01 100.0% 81.4%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.73 49.0 4.54e-01 70.5% 54.1%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.73 43.0 5.17e-01 91.0% 88.1%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.73 42.0 5.40e-01 93.4% 100.0%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.72 40.0 4.75e-01 87.3% 78.1%
2zdiC00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.72 51.0 5.42e-01 72.3% 95.3%
6h2dS01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.72 66.0 5.90e-01 97.0% 85.2%
3ajwA00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 46.0 5.08e-01 71.1% 79.9%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 46.0 5.53e-01 84.9% 100.0%
6gy8A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.70 61.0 4.85e-01 94.0% 74.4%
6w08A01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.70 65.0 5.03e-01 100.0% 76.0%
2rp4A00 6.10.280.60 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain 0.70 26.0 3.97e-01 84.9% 80.3%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.70 63.0 5.01e-01 97.6% 84.3%
4dlqA02 1.25.40.610 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.70 36.0 4.58e-01 88.6% 85.3%
4abxA02 6.10.140.1090 Special › Helix non-globular › Helix Hairpins › 0.69 33.0 4.43e-01 71.1% 85.1%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.69 52.0 5.79e-01 95.2% 98.5%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.69 40.0 4.20e-01 93.4% 62.4%
3ok8A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.68 45.0 4.11e-01 70.5% 50.2%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 47.0 4.02e-01 75.3% 45.4%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.67 36.0 4.30e-01 89.8% 77.3%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.66 36.0 4.03e-01 89.8% 66.4%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.66 37.0 4.40e-01 91.0% 82.4%
1qoyA00 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.65 59.0 4.86e-01 99.4% 68.0%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 56.0 5.39e-01 92.8% 80.5%
3k1hA00 3.30.1120.180 Alpha Beta › 2-Layer Sandwich › Arylsulfatase, C-terminal domain › Flagellar FLiS export co-chaperone, HP1076 0.64 35.0 4.10e-01 89.2% 74.8%
1dn1B00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 57.0 5.20e-01 97.0% 79.7%
2oerA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 38.0 3.73e-01 81.9% 53.6%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 44.0 3.94e-01 71.1% 65.9%
1a7eA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.63 31.0 3.62e-01 87.3% 64.4%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.63 44.0 3.75e-01 71.1% 48.5%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.60 33.0 3.64e-01 88.0% 64.7%
6a95A01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.59 37.0 4.25e-01 88.6% 83.3%
1by1A00 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.57 38.0 3.51e-01 84.3% 51.7%
1nfvA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 47.0 4.72e-01 96.4% 86.4%
4nn1A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 34.0 3.24e-01 83.7% 48.8%
7qx4A01 1.20.190.10 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain 0.55 46.0 4.06e-01 88.0% 68.8%
2qqyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 42.0 4.62e-01 92.2% 100.0%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 44.0 4.49e-01 96.4% 91.4%
2vxxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 47.0 4.68e-01 97.6% 93.6%
7xxiA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.52 44.0 3.67e-01 91.6% 73.1%
1flcB00 3.90.20.10 Alpha Beta › Alpha-Beta Complex › Hemagglutinin Ectodomain; Chain B › 0.52 35.0 3.59e-01 72.9% 70.4%
2yw6B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.52 42.0 4.47e-01 90.4% 95.3%
1tj7A02 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.51 46.0 3.86e-01 98.2% 61.6%
3iq1B00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.51 44.0 4.55e-01 93.4% 98.1%
6wlvB01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.50 35.0 3.09e-01 80.7% 47.6%
ECOD (73)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1877523 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.82 55.0 6.55e-01 89.8% 100.0%
3702176 603.1.1.100 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.80 61.0 6.66e-01 95.8% 93.6%
3978919 604.10.1.1 ↗ alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PTS_IIA 0.80 47.0 5.72e-01 91.0% 88.2%
3484909 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.80 57.0 6.54e-01 90.4% 100.0%
3718312 604.1.1.118 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › GOSR1_N 0.80 61.0 6.50e-01 95.8% 90.3%
3778551 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.79 53.0 6.32e-01 91.0% 98.3%
3896730 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.79 62.0 6.76e-01 91.6% 100.0%
3524431 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.79 56.0 6.37e-01 100.0% 96.0%
3236222 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.78 54.0 5.44e-01 72.3% 70.3%
4142346 5086.1.1.87 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.78 50.0 6.06e-01 72.3% 96.4%
4153446 604.12.1.4 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › ATG1-like_MIT1 0.78 51.0 6.16e-01 91.6% 99.1%
3813013 604.1.1.110 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › WIT1_2_N 0.78 68.0 6.99e-01 100.0% 96.2%
3432339 604.1.1.134 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF28715 0.77 62.0 6.04e-01 98.2% 76.7%
3418792 3755.3.1.400 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › NET2A_C 0.77 67.0 6.87e-01 95.2% 95.6%
4944680 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.77 51.0 3.33e-01 71.7% 16.1%
3649075 604.1.1.100 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › NET2A_C 0.77 72.0 7.05e-01 98.8% 93.7%
3847307 3939.1.1.319 ↗ alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › Rad50_zn_hook 0.77 55.0 3.83e-01 72.9% 46.4%
3712648 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.76 56.0 5.30e-01 75.9% 65.3%
3719591 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.76 70.0 6.37e-01 97.6% 82.3%
3544537 604.1.1.63 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_SESTD1 0.76 52.0 6.08e-01 89.2% 100.0%
3512594 3922.1.1.0 ↗ alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.76 54.0 4.16e-01 72.3% 42.4%
5064040 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.75 49.0 4.53e-01 71.7% 52.7%
3647975 3684.1.1.33 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF7795 0.75 62.0 6.16e-01 91.0% 84.1%
4024356 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.74 66.0 6.78e-01 99.4% 98.1%
3999040 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.74 62.0 6.17e-01 100.0% 86.5%
3729699 4121.1.1.0 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like 0.74 69.0 5.71e-01 100.0% 65.7%
4975983 150.1.1.0 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.73 59.0 6.32e-01 97.6% 97.2%
3616483 3755.3.1.280 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Spindly 0.73 52.0 4.21e-01 72.3% 95.9%
3594516 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.73 51.0 4.91e-01 96.4% 63.2%
4929363 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.73 50.0 5.92e-01 90.4% 100.0%
3184140 5086.1.1.87 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.73 47.0 5.59e-01 72.3% 93.9%
3188900 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.73 55.0 6.18e-01 89.2% 100.0%
5001019 4177.1.1.0 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.72 50.0 4.97e-01 71.7% 68.2%
3590504 3758.1.1.4 ↗ alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins › TelA 0.72 66.0 5.74e-01 98.2% 85.7%
3615123 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.72 47.0 4.62e-01 72.3% 61.1%
4028572 632.22.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.71 49.0 4.50e-01 71.7% 55.2%
4025349 3567.1.1.0 ↗ a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.71 46.0 5.15e-01 72.3% 83.1%
3592587 3567.1.1.0 ↗ a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.71 49.0 5.53e-01 78.9% 92.8%
3768053 3684.1.1.0 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.70 49.0 5.08e-01 92.2% 75.5%
3935064 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.70 50.0 4.07e-01 72.9% 92.9%
5083711 3755.3.1.0 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.70 49.0 4.27e-01 71.1% 61.7%
4993051 2004.1.1.87 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.70 50.0 3.37e-01 72.9% 27.9%
3637098 192.2.1.1 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.69 49.0 5.41e-01 81.9% 90.2%
3498783 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.69 53.0 4.92e-01 100.0% 64.9%
4978893 3755.3.1.632 ↗ alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Prefoldin 0.68 48.0 5.21e-01 72.3% 95.7%
3397986 3755.4.1.1 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 0.68 49.0 4.85e-01 74.7% 92.2%
3726818 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 46.0 4.77e-01 92.8% 73.5%
4370184 3758.2.1.1 ↗ alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB 0.67 62.0 6.03e-01 100.0% 97.3%
3611289 3291.1.1.0 ↗ alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.67 53.0 5.69e-01 81.9% 97.2%
4999186 3834.1.1.0 ↗ alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain 0.67 48.0 3.39e-01 72.9% 92.5%
3413217 192.2.1.1 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin_2 0.67 46.0 5.32e-01 77.7% 100.0%
3722421 604.8.1.0 ↗ alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.66 48.0 5.13e-01 88.6% 87.9%
3688677 4121.1.1.7 ↗ a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › PF26616 0.66 61.0 4.60e-01 100.0% 44.9%
3881581 310.2.1.11 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › DUF4456 0.65 57.0 5.76e-01 98.2% 95.2%
4507521 304.107.1.3 ↗ a+b two layers › Alpha-beta plaits › Aminomethyltransferase folate-binding domain › Aminomethyltransferase folate-binding domain › TrmE_N 0.63 42.0 3.58e-01 96.4% 40.0%
3777887 604.8.1.0 ↗ alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.63 53.0 5.22e-01 91.6% 84.6%
3276221 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.62 44.0 4.92e-01 72.3% 100.0%
3712573 5086.1.1.0 ↗ alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.62 44.0 4.73e-01 72.3% 90.7%
3928095 109.4.1.373 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG4_m 0.61 56.0 3.95e-01 100.0% 46.8%
4944765 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.61 44.0 3.12e-01 73.5% 48.5%
4567535 1203.1.2.0 ↗ alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 0.60 46.0 3.86e-01 80.1% 79.6%
3211688 5001.1.1.44 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srv 0.60 51.0 4.13e-01 92.2% 69.5%
4978506 3714.1.1.0 ↗ a+b two layers › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain 0.60 39.0 3.79e-01 71.7% 57.9%
4952130 3714.1.1.1 ↗ a+b two layers › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › LonC_helical 0.59 39.0 3.49e-01 71.7% 47.8%
3391391 4177.1.1.16 ↗ alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FAP206 0.58 51.0 4.04e-01 93.4% 49.4%
3878887 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.57 44.0 3.64e-01 97.0% 44.7%
3770213 1075.4.1.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.57 48.0 3.74e-01 88.6% 78.8%
4022885 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 39.0 3.26e-01 91.6% 39.3%
3614715 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.55 49.0 4.62e-01 98.8% 79.0%
3903882 5001.1.1.1 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.54 44.0 3.58e-01 94.0% 45.8%
3590372 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.52 43.0 4.19e-01 86.7% 85.6%
4031920 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.52 42.0 4.12e-01 86.7% 80.0%
3205634 630.1.1.0 ↗ a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain 0.51 42.0 4.10e-01 87.3% 95.7%