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ORF65
Euk-VirIctalurid_herpesvirus_1
ORF65__NP_041157__Ictalurid_herpesvirus_1__10401
Identity
- Accession:
- NP_041157 ↗
- Protein ID:
- ORF65
- Kingdom:
- euk
Quality
32.7
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Alloherpesviridae›
Ictavirus›
Ictalurid_herpesvirus_1
TaxID: 10401
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 537-591_617-660
D2
medium
residues 1255-1293_1364-1434
D3
medium
residues 1294-1363
Domain cluster:
representative
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2hroA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.75 | 56.0 | 4.58e-01 | 80.0% | 77.3% |
| 1mhyG02 | 1.20.1280.30 | Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 | 0.75 | 46.0 | 4.61e-01 | 77.1% | 60.3% |
| 3owaB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.71 | 52.0 | 4.00e-01 | 78.6% | 73.2% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.69 | 58.0 | 4.51e-01 | 92.9% | 91.4% |
| 2p6vA00 | 1.20.120.1110 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › TAFH/NHR1 domain | 0.69 | 49.0 | 4.44e-01 | 75.7% | 68.0% |
| 4kjmA02 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.69 | 48.0 | 5.36e-01 | 72.9% | 92.7% |
| 3oxfA05 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.68 | 44.0 | 4.29e-01 | 75.7% | 61.3% |
| 1fafA00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.68 | 44.0 | 4.25e-01 | 78.6% | 59.5% |
| 2ra1A01 | 1.20.58.790 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 51.0 | 4.49e-01 | 80.0% | 78.6% |
| 1j8yF01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.63 | 50.0 | 4.70e-01 | 85.7% | 77.9% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.61 | 46.0 | 4.59e-01 | 81.4% | 82.4% |
| 2zxqA06 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.60 | 48.0 | 4.93e-01 | 92.9% | 90.9% |
| 1ynjD04 | 2.40.40.20 | Mainly Beta › Beta Barrel › Barwin-like endoglucanases › | 0.59 | 42.0 | 3.41e-01 | 85.7% | 37.2% |
| 1n69B00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.58 | 46.0 | 4.42e-01 | 87.1% | 87.5% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 41.0 | 3.10e-01 | 75.7% | 31.2% |
| 1ga3A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.58 | 41.0 | 3.54e-01 | 75.7% | 95.6% |
| 3qbrX00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.58 | 41.0 | 3.19e-01 | 80.0% | 32.9% |
| 1xl3C00 | 1.20.1280.80 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.58 | 43.0 | 3.98e-01 | 80.0% | 62.6% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.57 | 39.0 | 3.67e-01 | 71.4% | 72.7% |
| 7yh2B01 | 3.30.1380.20 | Alpha Beta › 2-Layer Sandwich › Muramoyl-pentapeptide Carboxypeptidase; domain 2 › Trafficking protein particle complex subunit 3 | 0.57 | 42.0 | 3.35e-01 | 78.6% | 87.3% |
| 3unoE00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 44.0 | 3.35e-01 | 84.3% | 88.6% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.55 | 38.0 | 3.65e-01 | 71.4% | 74.1% |
| 2fu2A00 | 1.20.1440.50 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like | 0.55 | 45.0 | 4.43e-01 | 94.3% | 88.5% |
| 5idyA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.55 | 40.0 | 2.79e-01 | 80.0% | 44.3% |
| 2g8yA01 | 1.10.1530.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical Oxidoreductase Yiak; Chain: A, domain 1 › Malate/L-lactate/L-sulpholactate dehydrogenase, four-helix barrel | 0.55 | 44.0 | 3.76e-01 | 88.6% | 95.6% |
| 1u9pA00 | 1.10.1220.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant › Met repressor-like | 0.54 | 47.0 | 4.31e-01 | 100.0% | 93.8% |
| 3llkA02 | 1.20.120.310 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain | 0.54 | 42.0 | 3.40e-01 | 87.1% | 76.2% |
| 1yozA00 | 1.10.3200.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like | 0.54 | 39.0 | 3.43e-01 | 80.0% | 59.3% |
| 2dlaA01 | 1.20.930.50 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.53 | 42.0 | 3.21e-01 | 85.7% | 75.0% |
| 7jveC01 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.53 | 45.0 | 3.14e-01 | 95.7% | 66.5% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.53 | 39.0 | 3.68e-01 | 78.6% | 64.7% |
| 1vkeB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.53 | 38.0 | 3.41e-01 | 77.1% | 84.2% |
| 3hl6A02 | 1.20.58.700 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 42.0 | 3.57e-01 | 87.1% | 59.1% |
| 3qwlA03 | 1.10.472.80 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Ypt/Rab-GAP domain of gyp1p, domain 3 | 0.52 | 42.0 | 3.49e-01 | 92.9% | 94.1% |
| 4ur7A00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.52 | 39.0 | 2.62e-01 | 82.9% | 89.1% |
| 3bjdA01 | 1.10.1240.20 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain | 0.52 | 38.0 | 3.51e-01 | 77.1% | 68.2% |
| 8e9gE01 | 1.10.10.1590 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › NADH-quinone oxidoreductase subunit E | 0.51 | 33.0 | 3.50e-01 | 78.6% | 74.6% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3484228 | 4030.1.1.0 ↗ | alpha bundles › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz › alpha-helical domain in subunits of heterodimeric actin filament capping protein Capz | 0.82 | 43.0 | 4.82e-01 | 72.9% | 65.5% |
| 3384318 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.79 | 55.0 | 5.35e-01 | 71.4% | 70.7% |
| 4277294 | 607.1.1.1 ↗ | alpha arrays › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › PEP-utilisers_N | 0.76 | 57.0 | 4.75e-01 | 80.0% | 82.5% |
| 3475373 | 1128.1.1.2 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 | 0.76 | 57.0 | 5.62e-01 | 80.0% | 86.7% |
| 3621337 | 1128.1.1.2 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 | 0.75 | 58.0 | 4.82e-01 | 82.9% | 55.8% |
| None | — | 0.65 | 50.0 | 3.48e-01 | 84.3% | 89.4% | |
| 4104246 | 1128.1.1.2 ↗ | alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2 | 0.65 | 57.0 | 5.62e-01 | 97.1% | 92.0% |
| 4051951 | 605.2.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 | 0.63 | 40.0 | 3.73e-01 | 72.9% | 50.0% |
| 3775067 | 198.1.1.21 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapA, SapB_2 | 0.63 | 46.0 | 3.83e-01 | 84.3% | 45.0% |
| 3925617 | 192.5.1.14 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA | 0.63 | 47.0 | 4.38e-01 | 78.6% | 91.8% |
| 3497021 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.63 | 45.0 | 3.95e-01 | 81.4% | 50.5% |
| 5018042 | 3896.1.1.0 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase | 0.61 | 46.0 | 3.29e-01 | 81.4% | 62.4% |
| 4990861 | 2005.1.1.7 ↗ | a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1d | 0.60 | 46.0 | 2.67e-01 | 81.4% | 50.1% |
| 4652719 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.60 | 44.0 | 3.98e-01 | 78.6% | 75.8% |
| 3175217 | 622.1.1.27 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › Rer1 | 0.59 | 42.0 | 3.85e-01 | 75.7% | 69.5% |
| 4189854 | 2004.1.3.2 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › Pyruvate-ferredoxin oxidoreductase, PFOR, domain III › POR,EKR | 0.59 | 42.0 | 2.85e-01 | 75.7% | 72.2% |
| 4457135 | 1197.1.1.1 ↗ | alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf | 0.59 | 43.0 | 3.08e-01 | 80.0% | 73.5% |
| 4237962 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.59 | 44.0 | 2.68e-01 | 78.6% | 63.3% |
| 3513582 | 192.8.1.36 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › M_domain | 0.57 | 40.0 | 3.43e-01 | 81.4% | 46.4% |
| 3824340 | 2006.1.4.19 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › XPG_N | 0.56 | 41.0 | 3.08e-01 | 78.6% | 79.4% |
| 3994538 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 41.0 | 2.76e-01 | 81.4% | 19.7% |
| 4279091 | 276.1.1.1 ↗ | a+b three layers › L-sulfolactate dehydrogenase-like › L-sulfolactate dehydrogenase-like › L-sulfolactate dehydrogenase-like › Ldh_2 | 0.52 | 42.0 | 2.74e-01 | 90.0% | 99.1% |
| 3942848 | 2003.1.2.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain | 0.52 | 35.0 | 2.64e-01 | 74.3% | 24.3% |
| 5059333 | 2488.1.1.1 ↗ | a/b three-layered sandwiches › alpha/beta knot › alpha/beta knot › alpha/beta knot › SpoU_methylase | 0.51 | 45.0 | 3.21e-01 | 100.0% | 67.3% |