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ORF66

Euk-Vir

Bovine_gammaherpesvirus_6

ORF66__YP_009042045__Bovine_gammaherpesvirus_6__1504288

Identity

Accession:
YP_009042045 ↗
Protein ID:
ORF66
Kingdom:
euk

Quality

76.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 7-151
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3axjB02 1.20.58.200 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 0.64 38.0 4.80e-01 80.0% 100.0%
1dk8A02 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.62 34.0 4.30e-01 86.9% 90.6%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.61 42.0 4.48e-01 89.7% 79.4%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.60 33.0 3.65e-01 99.3% 64.7%
2wviA00 1.25.40.430 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.59 36.0 3.55e-01 97.9% 55.6%
1y4cA03 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.59 39.0 4.34e-01 86.9% 85.8%
6wb9201 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 39.0 3.08e-01 100.0% 33.2%
3behB01 1.20.120.540 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels 0.58 40.0 4.35e-01 86.9% 85.5%
1u89A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 35.0 3.62e-01 77.2% 61.9%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.56 42.0 3.66e-01 87.6% 52.1%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.55 34.0 3.99e-01 77.9% 85.8%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.54 35.0 4.00e-01 75.9% 89.6%
3tp3A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 39.0 3.88e-01 73.1% 87.2%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 39.0 4.22e-01 89.7% 90.9%
1j1jA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.53 34.0 3.58e-01 94.5% 69.7%
8g52B01 1.25.40.920 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TRAP transporter T-component 0.53 45.0 3.62e-01 100.0% 47.8%
1dbhA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.53 43.0 3.81e-01 86.2% 96.2%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.53 39.0 3.99e-01 75.2% 80.4%
3ro3A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 35.0 3.45e-01 100.0% 61.0%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.52 38.0 4.18e-01 89.7% 94.0%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.52 34.0 3.33e-01 86.2% 61.0%
3nxcA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 37.0 3.50e-01 73.8% 70.6%
4flbA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 34.0 3.60e-01 100.0% 74.0%
1zymA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.51 31.0 3.33e-01 82.8% 69.0%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3603670 109.10.1.1 alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin 0.66 37.0 3.25e-01 77.9% 37.1%
3796225 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 44.0 4.71e-01 89.7% 77.6%
3730281 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.61 43.0 4.01e-01 86.9% 57.8%
5080053 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.61 44.0 4.60e-01 90.3% 80.7%
4441542 601.25.1.1 alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.57 46.0 4.50e-01 90.3% 76.9%
3498285 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.57 38.0 3.87e-01 86.9% 69.3%
3735128 601.1.1.90 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF3433 0.56 47.0 4.34e-01 89.7% 88.6%
3933439 601.25.1.1 alpha bundles › Four-helical up-and-down bundle › TrmE connector domain › TrmE connector domain › MnmE_helical 0.55 44.0 4.26e-01 89.7% 76.2%
3697809 109.4.1.1323 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_IMB1 0.54 40.0 2.82e-01 100.0% 25.2%
4946071 1076.1.1.0 alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related 0.54 46.0 4.02e-01 93.8% 82.2%
2671884 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.53 42.0 4.15e-01 87.6% 79.5%
3347110 3684.1.1.2 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 0.52 43.0 3.60e-01 86.9% 55.6%
4945270 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 38.0 3.92e-01 99.3% 78.6%
3222708 3343.1.1.2 alpha complex topology › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › gamma-tubulin complex protein 4 (GCP4) › GCP_C_terminal,GCP_N_terminal 0.52 46.0 3.10e-01 100.0% 49.3%
4972775 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.52 41.0 3.59e-01 86.2% 81.3%
4971764 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.51 37.0 3.31e-01 80.0% 52.2%
3671005 611.3.1.0 alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 0.51 42.0 4.36e-01 100.0% 94.8%
3756667 109.25.1.0 alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A 0.50 40.0 3.78e-01 100.0% 70.6%
4958843 3543.1.1.13 alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › DUF308 0.50 41.0 3.84e-01 86.9% 85.0%
D2 high residues 276-436
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03117.21 best Herpes_UL49_1 202.2 1.20e-59 99.4% 70.7%
D3 medium residues 224-275
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03117.21 best Herpes_UL49_1 41.2 1.90e-10 100.0% 21.4%
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1mzvA00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.71 60.0 3.94e-01 94.2% 32.9%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.69 46.0 3.83e-01 88.5% 41.9%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.62 42.0 3.97e-01 73.1% 60.0%
3i2fA02 1.10.3020.10 Mainly Alpha › Orthogonal Bundle › alpha-amino acid ester hydrolase ( Helical cap domain) › alpha-amino acid ester hydrolase ( Helical cap domain) 0.61 43.0 3.56e-01 88.5% 41.1%
4g2aA02 1.20.58.1690 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 41.0 3.54e-01 86.5% 42.5%
2aizP01 3.30.1330.60 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › OmpA-like domain 0.59 46.0 3.71e-01 86.5% 55.0%
1kyoF00 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.59 41.0 3.66e-01 73.1% 66.2%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.58 43.0 3.58e-01 78.8% 70.0%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.58 45.0 3.93e-01 82.7% 76.6%
3gnlB02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 41.0 3.79e-01 80.8% 57.4%
2v4iB01 3.30.2330.10 Alpha Beta › 2-Layer Sandwich › arginine biosynthesis bifunctional protein fold › arginine biosynthesis bifunctional protein suprefamily 0.58 46.0 4.12e-01 90.4% 79.2%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.58 47.0 3.96e-01 92.3% 87.1%
6lo8F01 1.10.287.810 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mitochondrial import inner membrane translocase subunit tim13 like domains 0.57 42.0 3.78e-01 76.9% 75.4%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 48.0 4.04e-01 96.2% 97.8%
4qxbB00 6.10.280.250 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 43.0 3.99e-01 88.5% 61.8%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.57 41.0 3.59e-01 84.6% 50.0%
2qupA00 1.20.120.490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain 0.57 47.0 3.65e-01 94.2% 77.3%
3lstA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 44.0 2.98e-01 100.0% 37.7%
3whjA00 6.10.140.1710 Special › Helix non-globular › Helix Hairpins › 0.54 40.0 3.21e-01 80.8% 59.5%
3hgtA00 3.40.50.12360 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 44.0 2.86e-01 100.0% 39.9%
1s5jA04 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.52 38.0 3.70e-01 86.5% 68.9%
3wgbC02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.52 45.0 3.87e-01 98.1% 97.6%
5dukB00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 41.0 3.86e-01 90.4% 82.1%
2qkdA04 2.60.120.1040 Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain 0.51 37.0 2.82e-01 78.8% 57.5%
4pxoA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.51 44.0 3.32e-01 100.0% 93.1%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3519973 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.67 45.0 2.85e-01 88.5% 14.7%
4000262 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.67 48.0 3.96e-01 88.5% 43.3%
4457834 7510.1.1.3 a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › FA_synthesis 0.64 47.0 3.31e-01 80.8% 30.6%
3408508 3712.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Med11 0.62 43.0 3.74e-01 88.5% 47.5%
3170491 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.62 44.0 2.91e-01 76.9% 22.3%
4132296 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.62 44.0 4.26e-01 76.9% 78.3%
4945538 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.60 42.0 3.90e-01 80.8% 57.1%
3719637 192.12.1.0 alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM 0.60 45.0 3.77e-01 82.7% 67.8%
3670246 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.59 42.0 3.74e-01 94.2% 52.0%
1286954 109.1.1.0 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C 0.59 47.0 3.42e-01 90.4% 82.0%
3710918 223.2.1.9 a+b three layers › Profilin-like › profilin-like › profilin-like › Sedlin_N 0.57 41.0 2.76e-01 75.0% 24.7%
3216820 2007.2.3.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.56 47.0 2.98e-01 96.2% 29.0%
3339474 5059.1.1.8 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Mg_trans_NIPA 0.56 46.0 3.64e-01 100.0% 78.4%
4353448 604.11.1.1 alpha bundles › Spectrin repeat-like › XseB-like › XseB-like › Exonuc_VII_S 0.56 38.0 3.57e-01 82.7% 56.9%
3731535 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.56 45.0 3.59e-01 86.5% 45.0%
5006331 4168.1.1.1 alpha duplicates or obligate multimers › HAMP domain › HAMP domain › HAMP domain › HAMP 0.54 44.0 4.19e-01 96.2% 76.9%
4400807 605.1.1.174 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HAMP 0.53 43.0 4.05e-01 92.3% 72.3%
3516873 159.1.1.3 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › Hypothetical protein AF_0060 › DUF1599 0.52 38.0 3.55e-01 90.4% 93.8%
3601375 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.52 44.0 2.92e-01 100.0% 59.6%
5081618 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.52 41.0 3.17e-01 88.5% 40.8%
3576883 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.51 44.0 3.64e-01 100.0% 95.0%
3464457 207.1.1.95 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_14 0.51 43.0 2.83e-01 100.0% 36.8%
4239789 7579.1.1.47 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › BD-FAE 0.50 40.0 2.64e-01 100.0% 51.4%