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ORF66
Euk-VirFelis_catus_gammaherpesvirus_1
ORF66__YP_009173946__Felis_catus_gammaherpesvirus_1__1452540
Identity
- Accession:
- YP_009173946 ↗
- Protein ID:
- ORF66
- Kingdom:
- euk
Quality
67.5
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Percavirus›
Felid_gammaherpesvirus_1
TaxID: 1452540
Cluster
View cluster (9 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 39-151
Domain cluster:
representative
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4gycA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 44.0 | 3.50e-01 | 82.3% | 58.2% |
| 1tqnA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.55 | 46.0 | 3.06e-01 | 92.0% | 64.7% |
| 2oyyA00 | 6.10.80.10 | Special › Helix non-globular › DNA polymerase; domain 1 › Hexameric tyrosine-coordinated heme protein (HTHP) | 0.54 | 31.0 | 3.84e-01 | 89.4% | 90.1% |
| 2e9fB01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.52 | 35.0 | 3.77e-01 | 75.2% | 82.3% |
| 2vm6A00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.51 | 36.0 | 3.35e-01 | 85.8% | 56.9% |
| 2bvlA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 30.0 | 3.41e-01 | 78.8% | 76.7% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 30.0 | 3.38e-01 | 78.8% | 77.6% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5015029 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.54 | 44.0 | 3.32e-01 | 89.4% | 76.4% |
| 5031190 | 4952.1.1.0 ↗ | alpha arrays › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like › L-aspartase N-terminal domain-like | 0.50 | 39.0 | 4.04e-01 | 94.7% | 86.7% |
D2
medium
residues 218-285
Domain cluster:
rep: ORF66__YP_009042045__Bovine_gammaherpesvirus_6__1504288__D224-275
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03117.21 best | Herpes_UL49_1 | 55.7 | 7.10e-15 | 100.0% | 29.3% |
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5ijiA01 | 1.10.8.500 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › HAMP domain in histidine kinase | 0.57 | 39.0 | 4.20e-01 | 70.6% | 91.2% |
| 3keyA01 | 1.10.10.1080 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Stn1, N-terminal wHTH domain | 0.55 | 40.0 | 3.73e-01 | 77.9% | 62.1% |
| 3d0cB00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.55 | 48.0 | 3.16e-01 | 98.5% | 93.7% |
| 2ipcA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.55 | 38.0 | 2.63e-01 | 72.1% | 74.8% |
| 2pg0A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.54 | 38.0 | 3.21e-01 | 73.5% | 70.9% |
| 3oioA00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.51 | 43.0 | 3.67e-01 | 94.1% | 86.6% |
| 1am4A00 | 1.10.555.10 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein | 0.51 | 43.0 | 3.20e-01 | 100.0% | 78.4% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4496758 | 5050.1.1.86 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › LysE | 0.62 | 43.0 | 3.07e-01 | 72.1% | 52.2% |
| 5009561 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.55 | 34.0 | 3.25e-01 | 95.6% | 50.6% |
| 5021443 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.55 | 39.0 | 3.49e-01 | 76.5% | 89.0% |
| 3693357 | 177.1.1.2 ↗ | alpha bundles › Phospholipase C/P1 nuclease › Phospholipase C/P1 nuclease › Phospholipase C/P1 nuclease › S1-P1_nuclease | 0.53 | 37.0 | 2.57e-01 | 73.5% | 34.8% |
| 3405450 | 2498.1.1.62 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M76 | 0.53 | 43.0 | 3.07e-01 | 89.7% | 60.0% |
| 3974456 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.52 | 36.0 | 3.51e-01 | 72.1% | 89.3% |
| 3470995 | 109.4.1.470 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS2 | 0.52 | 44.0 | 2.81e-01 | 100.0% | 35.7% |
| 3687745 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.51 | 37.0 | 3.04e-01 | 76.5% | 50.4% |
| 4186374 | 6102.1.1.1 ↗ | alpha arrays › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › N-terminal domain of segregation and condensation protein A, ScpA › SMC_ScpA | 0.51 | 37.0 | 2.81e-01 | 77.9% | 32.7% |
| 5032699 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.50 | 36.0 | 3.14e-01 | 97.1% | 47.3% |
D3
medium
residues 286-386
Domain cluster:
rep: hypothetical_protein__YP_009551880__Rhinolophus_gammaherpesvirus_1__2054179__D262-332
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03117.21 best | Herpes_UL49_1 | 131.8 | 4.00e-38 | 100.0% | 45.4% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5051531 | 375.1.1.0 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related | 0.80 | 33.0 | 5.17e-01 | 74.3% | 100.0% |
| 4836960 | 375.5.1.1 ↗ | few secondary structure elements › Rubredoxin-like › NOB1 zinc finger-like › NOB1 zinc finger-like › NOB1_Zn_bind | 0.58 | 30.0 | 3.57e-01 | 79.2% | 71.8% |
| 3586909 | 12.1.1.4 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain › Alpha-L-AF_C | 0.53 | 33.0 | 3.07e-01 | 100.0% | 47.7% |
| 5070342 | 4043.1.1.2 ↗ | a+b complex topology › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › C-terminal domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_7 | 0.52 | 37.0 | 3.89e-01 | 92.1% | 83.3% |
| 3609495 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.52 | 27.0 | 3.06e-01 | 76.2% | 65.0% |
D4
medium
residues 387-446
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03117.21 best | Herpes_UL49_1 | 52.6 | 6.20e-14 | 93.3% | 24.4% |
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2aw4Z00 | 4.10.830.30 | Few Secondary Structures › Irregular › 30s Ribosomal Protein S14; Chain N › Ribosomal protein L31 | 0.67 | 45.0 | 4.26e-01 | 75.0% | 58.6% |
| 3u04A00 | 3.90.45.10 | Alpha Beta › Alpha-Beta Complex › Peptide Deformylase › Peptide deformylase | 0.64 | 49.0 | 3.55e-01 | 83.3% | 58.7% |
| 2jxtA01 | 3.10.20.10 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › | 0.56 | 38.0 | 3.63e-01 | 73.3% | 59.2% |
| 2byvE05 | 3.10.20.90 | Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 | 0.56 | 42.0 | 3.90e-01 | 95.0% | 63.3% |
| 4m7xA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.56 | 34.0 | 3.04e-01 | 78.3% | 38.5% |
| 2e9xB01 | 3.40.5.50 | Alpha Beta › 3-Layer(aba) Sandwich › Ribosomal Protein L9; domain 1 › | 0.55 | 36.0 | 3.59e-01 | 70.0% | 80.3% |
| 2r6fA04 | 1.10.8.280 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › ABC transporter ATPase domain-like | 0.53 | 37.0 | 3.07e-01 | 75.0% | 49.2% |
| 1cbfA02 | 3.30.950.10 | Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain | 0.50 | 37.0 | 3.08e-01 | 83.3% | 83.5% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3901896 | 209.1.1.1 ↗ | a+b complex topology › C-type lectin-like › C-type lectin-like › C-type lectin-like › Lectin_C | 0.57 | 42.0 | 2.92e-01 | 85.0% | 21.8% |
| 3453549 | 221.1.1.0 ↗ | a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like | 0.57 | 40.0 | 3.38e-01 | 78.3% | 76.5% |
| 3487873 | 377.1.1.0 ↗ | few secondary structure elements › Glucocorticoid receptor-like › LIM domain-like › LIM domain-like | 0.51 | 34.0 | 3.50e-01 | 71.7% | 78.3% |