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ORF6

Euk-Vir

Human_gammaherpesvirus_8

ORF6__YP_001129352__Human_gammaherpesvirus_8__37296

Identity

Accession:: YP_001129352 ↗
Protein ID:: ORF6
Kingdom:: euk

Quality

73.9 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Rhadinovirus› Human_gammaherpesvirus_8

TaxID: 37296

Cluster

View cluster (33 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 996-1077

PDB

Domain cluster: rep: JM5__YP_238308__Macaca_fuscata_rhadinovirus__272551__D1010-1077

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	44.9	3.80e-12	100.0%	7.2%

D2 medium residues 13-252_683-721

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	243.0	5.70e-72	86.0%	22.8%

CATH (1)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
5is2A01	3.30.70.260	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain	0.53	20.0	3.33e-01	73.8%	100.0%

ECOD (3)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
7679	4174.1.1.1 ↗	a+b complex topology › N-terminal domain in viral ssDNA binding protein › N-terminal domain in viral ssDNA binding protein › N-terminal domain in viral ssDNA binding protein › Viral_DNA_bp	0.91	77.0	7.78e-01	86.0%	95.6%
3236680	304.9.1.0 ↗	a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD	0.52	26.0	3.29e-01	72.4%	77.1%
4087300	304.8.1.5 ↗	a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NIL	0.51	18.0	2.96e-01	82.1%	84.8%

D3 medium residues 253-415_605-682_722-740

PDB

Domain cluster: rep: major_DNA_binding_protein__NP_042934__Human_betaherpesvirus_6A__32603__D217-426_621-688

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	142.6	1.20e-41	63.5%	15.0%
PF00747.23	Viral_DNA_bp	96.4	1.10e-27	37.7%	7.5%

D4 medium residues 416-485_857-918_969-989

PDB

Domain cluster: rep: single-stranded_DNA-binding_protein__YP_001033958__Gallid_alphaherpesvirus_2__10390__D473-534_915-970

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	74.6	4.00e-21	45.8%	6.0%

D5 medium residues 486-511_587-604_841-856_919-947

PDB

D6 medium residues 527-586_757-840

PDB

Domain cluster: rep: single-stranded_DNA-binding_protein__YP_009176908__Testudinid_alphaherpesvirus_3__2560801__D537-651_841-913

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	80.9	5.30e-23	59.7%	7.5%
PF00747.23	Viral_DNA_bp	31.8	3.40e-08	41.7%	5.7%

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3efzB00	1.20.190.20	Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain	0.57	39.0	3.38e-01	86.8%	44.0%
3f0cA02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.53	38.0	3.86e-01	85.4%	73.6%
7b00A01	1.20.1740.10	Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I	0.51	40.0	2.86e-01	82.6%	75.5%
1a7eA00	1.20.120.50	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like	0.50	33.0	3.67e-01	95.1%	82.2%
1h6gA02	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.50	39.0	4.18e-01	100.0%	96.0%

ECOD (7)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3939419	601.1.2.96 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › MENTAL	0.59	35.0	3.72e-01	76.4%	64.6%
3927056	603.1.1.1 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin	0.59	49.0	4.34e-01	89.6%	85.7%
4992346	102.2.1.0 ↗	alpha arrays › HhH/H2TH › H2TH › H2TH	0.56	25.0	3.19e-01	74.3%	70.0%
4993658	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.54	35.0	3.89e-01	73.6%	82.3%
3724318	5069.1.1.7 ↗	alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561	0.53	36.0	3.22e-01	70.1%	49.0%
1764103	606.1.1.1 ↗	alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop	0.52	42.0	3.97e-01	88.2%	97.2%
4939412	4163.1.1.4 ↗	alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › PF27418	0.51	32.0	3.42e-01	74.3%	71.2%