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ORF6

Euk-Vir

Macaca_nemestrina_rhadinovirus_2

ORF6__YP_010084546__Macaca_nemestrina_rhadinovirus_2__123630

Identity

Accession:: YP_010084546 ↗
Protein ID:: ORF6
Kingdom:: euk

Quality

72.3 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Orthoherpesviridae› Rhadinovirus› Macaca_nemestrina_rhadinovirus_2

TaxID: 123630

Cluster

View cluster (33 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 12-43_174-199_681-720

PDB

Domain cluster: representative

D2 medium residues 44-109_128-173_200-215

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	58.6	2.90e-16	53.1%	5.7%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
7679	4174.1.1.1 ↗	a+b complex topology › N-terminal domain in viral ssDNA binding protein › N-terminal domain in viral ssDNA binding protein › N-terminal domain in viral ssDNA binding protein › Viral_DNA_bp	0.88	84.0	6.31e-01	100.0%	72.3%

D3 medium residues 110-127_216-260_289-306

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	40.1	1.10e-10	71.6%	3.9%

ECOD (1)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4034078	5054.1.1.6 ↗	alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › TrkH	0.53	38.0	3.60e-01	76.5%	73.0%

D4 medium residues 261-288_307-429_612-646

PDB

Domain cluster: rep: major_DNA_binding_protein__NP_042934__Human_betaherpesvirus_6A__32603__D217-426_621-688

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	122.9	1.10e-35	67.2%	11.3%
PF00747.23	Viral_DNA_bp	31.4	4.40e-08	19.4%	3.1%

D5 medium residues 430-483

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	52.3	2.30e-14	100.0%	4.6%

CATH (4)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3ljcA02	1.20.58.1480	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.57	42.0	3.29e-01	83.3%	57.1%
1wx1A01	1.10.1610.10	Mainly Alpha › Orthogonal Bundle › 5,6-Dimethylbenzimidazole Phosphoribosyltransferase; Chain: A; domain 1 › Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (CobT), small domain	0.56	38.0	3.66e-01	85.2%	61.3%
3tp3A02	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.56	45.0	3.46e-01	100.0%	77.7%
1burS00	3.30.190.10	Alpha Beta › 2-Layer Sandwich › Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase › Ribulose bisphosphate carboxylase, small subunit	0.50	36.0	2.94e-01	83.3%	65.0%

ECOD (10)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4010088	162.1.1.0 ↗	alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD	0.60	48.0	4.20e-01	100.0%	56.7%
3319950	603.1.1.197 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF28744	0.59	45.0	3.39e-01	87.0%	33.5%
4153653	101.1.1.19 ↗	alpha arrays › HTH › HTH › Three-helical HTH › SRP_SPB	0.57	43.0	3.27e-01	85.2%	60.7%
4033128	3909.1.1.1 ↗	alpha bundles › NisB C-terminal helical domain › NisB C-terminal helical domain › NisB C-terminal helical domain › Lant_dehydr_C	0.55	40.0	2.92e-01	83.3%	68.8%
4020842	3209.1.1.0 ↗	a+b two layers › RPL28 › RPL28 › RPL28	0.53	39.0	2.94e-01	79.6%	30.7%
3928473	5001.1.1.66 ↗	alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg	0.51	40.0	2.60e-01	94.4%	31.0%
3697356	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.51	38.0	3.39e-01	83.3%	61.2%
4932399	2004.1.1.43 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54	0.50	36.0	2.30e-01	83.3%	28.3%
4937476	101.1.1.19 ↗	alpha arrays › HTH › HTH › Three-helical HTH › SRP_SPB	0.50	36.0	3.01e-01	83.3%	91.3%
5024364	2004.1.1.43 ↗	a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SRP54	0.50	36.0	2.31e-01	83.3%	29.7%

D6 medium residues 484-501_647-680_721-736_906-949_970-996

PDB

D7 medium residues 502-513_527-611_737-749_829-861

PDB

D8 medium residues 750-828

PDB

Domain cluster: representative

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	71.6	3.40e-20	100.0%	6.7%

CATH (5)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3hjeA03	1.10.150.200	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Maltooligosyl trehalose synthase; domain 3	0.68	51.0	4.90e-01	81.0%	100.0%
5jazA03	1.10.1740.10	Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif	0.65	40.0	3.79e-01	96.2%	52.7%
5cbgA00	1.10.287.70	Mainly Alpha › Orthogonal Bundle › Helix Hairpins ›	0.56	43.0	3.99e-01	89.9%	65.7%
2osaA00	1.10.555.10	Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein	0.51	39.0	3.03e-01	86.1%	58.7%
4boqA00	3.90.70.80	Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A ›	0.50	37.0	2.91e-01	79.7%	90.9%

ECOD (8)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3267527	1128.1.1.1 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR	0.60	45.0	4.62e-01	91.1%	82.7%
1346255	6140.1.1.1 ↗	alpha superhelices › Cdc45-Binding Domain in Sld3/Treslin › Cdc45-Binding Domain in Sld3/Treslin › Cdc45-Binding Domain in Sld3/Treslin › Sld3_STD	0.57	33.0	2.72e-01	83.5%	30.5%
4104246	1128.1.1.2 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR_2	0.55	40.0	4.09e-01	88.6%	80.0%
4015879	630.1.1.1 ↗	a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › Rubis-subs-bind	0.53	39.0	3.10e-01	83.5%	38.7%
3267852	1128.1.1.1 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR	0.52	41.0	4.16e-01	93.7%	86.3%
3262871	1128.1.1.1 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR	0.52	42.0	4.34e-01	87.3%	90.7%
4143378	524.1.1.4 ↗	alpha arrays › Ypt/Rab-GAP domain of gyp1p-like › Ypt/Rab-GAP domain of gyp1p › Ypt/Rab-GAP domain of gyp1p › SBE2_C	0.52	38.0	3.23e-01	78.5%	94.8%
3533312	1128.1.1.1 ↗	alpha bundles › LYR protein › LYR protein › LYR protein › Complex1_LYR	0.51	45.0	4.52e-01	94.9%	96.2%

D9 medium residues 997-1065

PDB

Domain cluster: rep: JM5__YP_238308__Macaca_fuscata_rhadinovirus__272551__D1010-1077

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00747.23 best	Viral_DNA_bp	33.7	9.40e-09	100.0%	5.9%