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ORF74
Euk-VirFelis_catus_gammaherpesvirus_1
ORF74__YP_009173955__Felis_catus_gammaherpesvirus_1__1452540
Identity
- Accession:
- YP_009173955 ↗
- Protein ID:
- ORF74
- Kingdom:
- euk
Quality
75.6
mean pLDDT
Taxonomy
Heunggongvirae›
Peploviricota›
Herviviricetes›
Herpesvirales›
Orthoherpesviridae›
Percavirus›
Felid_gammaherpesvirus_1
TaxID: 1452540
Cluster
View cluster (110 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 76-124_194-216
Domain cluster:
representative
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.70 | 40.0 | 3.63e-01 | 79.2% | 45.1% |
| 6a3kA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.63 | 48.0 | 3.96e-01 | 81.9% | 76.7% |
| 3wd6A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 48.0 | 4.10e-01 | 91.7% | 79.7% |
| 2i06A01 | 3.50.14.10 | Alpha Beta › 3-Layer(bba) Sandwich › Replication Terminator Protein (Tus); Chain A, domain 1 › Replication terminator Tus, domain 1 superfamily/Replication terminator Tus | 0.56 | 48.0 | 3.38e-01 | 93.1% | 34.6% |
| 3q18A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.53 | 39.0 | 3.43e-01 | 80.6% | 75.0% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3415313 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.72 | 58.0 | 3.69e-01 | 86.1% | 94.4% |
| 3269863 | 246.2.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos | 0.69 | 48.0 | 2.95e-01 | 72.2% | 31.6% |
| 3181226 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 46.0 | 3.87e-01 | 75.0% | 62.5% |
| 3200052 | 1174.1.1.0 ↗ | alpha complex topology › Potassium channel TMEM175 › Potassium channel TMEM175 › Potassium channel TMEM175 | 0.61 | 51.0 | 3.62e-01 | 90.3% | 83.3% |
| 3182733 | 5069.1.1.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct | 0.61 | 49.0 | 3.40e-01 | 90.3% | 65.4% |
| 3253260 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.60 | 45.0 | 3.95e-01 | 80.6% | 92.7% |
| 3380124 | 109.4.1.1266 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm, ARM_PUB | 0.60 | 50.0 | 3.16e-01 | 90.3% | 28.2% |
| 3821967 | 509.1.1.1 ↗ | alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › PAH | 0.56 | 39.0 | 3.86e-01 | 72.2% | 73.3% |
| 4963455 | 5065.1.1.3 ↗ | alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › BPD_transp_2 | 0.54 | 49.0 | 3.23e-01 | 100.0% | 67.2% |
| 4955754 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.53 | 44.0 | 3.50e-01 | 90.3% | 93.8% |
| 3661190 | 9.23.1.4 ↗ | beta barrels › Lipocalins/Streptavidin › Hypothetical protein BT_0869 › Hypothetical protein BT_0869 › PAP_fibrillin | 0.51 | 38.0 | 2.86e-01 | 79.2% | 94.3% |
| 4030463 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.51 | 45.0 | 2.69e-01 | 98.6% | 23.6% |
D2
medium
residues 125-193
Domain cluster:
representative
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1m6nA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.68 | 53.0 | 4.31e-01 | 85.5% | 48.9% |
| 2optA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.66 | 50.0 | 3.98e-01 | 81.2% | 61.8% |
| 5svlA01 | 1.10.287.940 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel | 0.65 | 49.0 | 5.00e-01 | 84.1% | 85.3% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.64 | 49.0 | 3.79e-01 | 81.2% | 77.6% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 46.0 | 4.72e-01 | 87.0% | 89.2% |
| 3ezhA00 | 1.20.120.960 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase NarX, sensor domain | 0.60 | 47.0 | 4.06e-01 | 87.0% | 93.9% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.59 | 41.0 | 4.42e-01 | 72.5% | 98.3% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.59 | 42.0 | 3.67e-01 | 87.0% | 49.1% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.56 | 43.0 | 3.98e-01 | 81.2% | 66.7% |
| 4akgA14 | 1.20.1280.160 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.55 | 43.0 | 3.70e-01 | 84.1% | 76.1% |
| 4gczA03 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.55 | 44.0 | 4.51e-01 | 85.5% | 93.8% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.55 | 41.0 | 4.38e-01 | 88.4% | 91.8% |
| 3uo2B02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.55 | 42.0 | 3.94e-01 | 82.6% | 75.0% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.54 | 36.0 | 3.66e-01 | 73.9% | 69.0% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 41.0 | 3.95e-01 | 82.6% | 88.9% |
| 3lnnB03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.54 | 43.0 | 4.42e-01 | 85.5% | 91.0% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.54 | 42.0 | 4.33e-01 | 82.6% | 89.1% |
| 1zhcA00 | 6.10.280.50 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 43.0 | 4.21e-01 | 89.9% | 86.8% |
| 1yg2A02 | 6.10.140.190 | Special › Helix non-globular › Helix Hairpins › | 0.53 | 41.0 | 3.73e-01 | 82.6% | 61.1% |
| 1vfiA00 | 1.10.246.100 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › Vanadium-binding protein 2 | 0.52 | 41.0 | 3.72e-01 | 87.0% | 84.2% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.51 | 41.0 | 3.55e-01 | 87.0% | 64.1% |
ECOD (22)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3475121 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.88 | 79.0 | 5.73e-01 | 97.1% | 39.4% |
| 3581946 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.88 | 76.0 | 5.64e-01 | 92.8% | 40.0% |
| 3944446 | 5069.1.3.1 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt | 0.77 | 56.0 | 5.20e-01 | 85.5% | 62.4% |
| 3234940 | 5001.1.1.69 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srd | 0.71 | 61.0 | 3.97e-01 | 95.7% | 23.3% |
| 3410128 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.67 | 46.0 | 4.78e-01 | 71.0% | 75.4% |
| 4000037 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.66 | 43.0 | 4.56e-01 | 71.0% | 76.7% |
| 3687276 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.64 | 49.0 | 4.62e-01 | 85.5% | 68.2% |
| 5041130 | 601.14.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin | 0.61 | 45.0 | 3.72e-01 | 85.5% | 44.0% |
| 3349382 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.60 | 48.0 | 3.90e-01 | 91.3% | 60.0% |
| 3495293 | 1203.1.2.0 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 | 0.60 | 45.0 | 3.63e-01 | 81.2% | 97.9% |
| 3687294 | 325.1.1.2 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › CO dehydrogenase molybdoprotein N-domain-like › Biotin_carb_C | 0.57 | 45.0 | 3.53e-01 | 87.0% | 74.2% |
| 2055367 | 650.1.1.3 ↗ | alpha bundles › Chaperone J-domain › Chaperone J-domain › Chaperone J-domain › HsbA | 0.56 | 41.0 | 4.15e-01 | 85.5% | 78.6% |
| 4147453 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.56 | 48.0 | 4.08e-01 | 94.2% | 93.6% |
| 4359654 | 605.2.1.3 ↗ | alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Seryl_tRNA_N | 0.55 | 47.0 | 4.05e-01 | 94.2% | 93.6% |
| 3684566 | 192.15.1.85 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › DUF3755 | 0.55 | 41.0 | 3.96e-01 | 79.7% | 70.0% |
| 4370630 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.55 | 44.0 | 4.04e-01 | 91.3% | 66.7% |
| 4497069 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.55 | 46.0 | 3.98e-01 | 91.3% | 93.3% |
| 3376917 | 192.24.1.8 ↗ | alpha bundles › Long alpha-hairpin › RPC62 helical hairpin domain › RPC62 helical hairpin domain › CDK5RAP3 | 0.54 | 43.0 | 4.16e-01 | 88.4% | 78.8% |
| 5021382 | 109.4.1.210 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 | 0.53 | 45.0 | 3.02e-01 | 98.6% | 33.0% |
| 4120406 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.53 | 40.0 | 3.47e-01 | 81.2% | 56.4% |
| 4507542 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.53 | 44.0 | 4.06e-01 | 92.8% | 96.7% |
| 4043484 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.51 | 40.0 | 3.52e-01 | 87.0% | 95.5% |
D3
medium
residues 217-332
Domain cluster:
rep: envelope_glycoprotein_UL33__NP_783781__Human_herpesvirus_5__10359__D194-311
CATH (46)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4xt1A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.91 | 86.0 | 6.20e-01 | 99.1% | 39.5% |
| 7sk7A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.90 | 72.0 | 5.39e-01 | 93.1% | 37.9% |
| 8h8jC01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.86 | 82.0 | 6.00e-01 | 99.1% | 42.8% |
| 6lw5A01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.84 | 78.0 | 5.58e-01 | 99.1% | 37.7% |
| 3oduB01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.84 | 74.0 | 5.42e-01 | 93.1% | 39.0% |
| 7xxiA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.81 | 76.0 | 5.51e-01 | 99.1% | 41.4% |
| 7xv3R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.80 | 67.0 | 4.99e-01 | 87.9% | 39.1% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.74 | 68.0 | 5.28e-01 | 100.0% | 76.0% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 50.0 | 3.98e-01 | 71.6% | 66.7% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 61.0 | 4.63e-01 | 92.2% | 87.0% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.71 | 65.0 | 5.18e-01 | 100.0% | 87.0% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.71 | 64.0 | 5.44e-01 | 100.0% | 93.6% |
| 8a1gC01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.70 | 62.0 | 5.40e-01 | 98.3% | 90.1% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.70 | 46.0 | 4.69e-01 | 75.9% | 67.2% |
| 4nswB01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 60.0 | 4.71e-01 | 100.0% | 73.0% |
| 1x04A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.68 | 61.0 | 5.12e-01 | 100.0% | 87.5% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.68 | 49.0 | 4.51e-01 | 100.0% | 57.5% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.68 | 45.0 | 4.64e-01 | 92.2% | 72.2% |
| 4q5rA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.67 | 42.0 | 4.29e-01 | 74.1% | 64.3% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.66 | 40.0 | 4.59e-01 | 73.3% | 82.4% |
| 3zciA00 | 1.20.58.1660 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 58.0 | 4.93e-01 | 96.6% | 72.3% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.66 | 46.0 | 4.75e-01 | 75.0% | 75.5% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.66 | 59.0 | 4.38e-01 | 100.0% | 45.2% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.65 | 51.0 | 5.08e-01 | 98.3% | 80.6% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.64 | 44.0 | 4.25e-01 | 71.6% | 63.9% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 57.0 | 4.33e-01 | 100.0% | 81.8% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.62 | 48.0 | 5.03e-01 | 81.0% | 95.1% |
| 2wdqD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.62 | 51.0 | 5.32e-01 | 93.1% | 99.0% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.62 | 56.0 | 4.76e-01 | 100.0% | 67.0% |
| 2yf4F00 | 1.10.3420.10 | Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain | 0.62 | 43.0 | 4.00e-01 | 71.6% | 78.3% |
| 2gscC00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.61 | 41.0 | 4.24e-01 | 96.6% | 72.7% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 49.0 | 4.57e-01 | 87.9% | 72.3% |
| 2fcwA00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.61 | 45.0 | 4.74e-01 | 79.3% | 99.1% |
| 1gqeA01 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.59 | 47.0 | 4.78e-01 | 85.3% | 92.9% |
| 2ihr101 | 1.20.58.410 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor | 0.58 | 47.0 | 4.88e-01 | 87.1% | 98.1% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.58 | 50.0 | 4.25e-01 | 91.4% | 73.8% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.58 | 52.0 | 4.74e-01 | 100.0% | 89.8% |
| 2okuA00 | 1.20.120.470 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Acyl-CoA dehydrogenase, C-terminal domain | 0.58 | 47.0 | 4.64e-01 | 96.6% | 82.0% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.58 | 45.0 | 3.36e-01 | 85.3% | 41.2% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.58 | 50.0 | 4.88e-01 | 100.0% | 97.7% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.58 | 50.0 | 4.59e-01 | 100.0% | 88.2% |
| 2yn7A00 | 1.10.3160.10 | Mainly Alpha › Orthogonal Bundle › Bbcrasp-1 › Bbcrasp-1 | 0.57 | 50.0 | 4.16e-01 | 97.4% | 79.4% |
| 1sj7C00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.57 | 50.0 | 4.46e-01 | 97.4% | 99.4% |
| 3qa8A04 | 1.20.1270.250 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.55 | 47.0 | 3.91e-01 | 100.0% | 79.0% |
| 1vfpB02 | 1.20.1110.10 | Mainly Alpha › Up-down Bundle › Calcium-transporting ATPase, transmembrane domain › Calcium-transporting ATPase, transmembrane domain | 0.52 | 45.0 | 3.11e-01 | 95.7% | 75.9% |
| 2q00B00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.51 | 40.0 | 3.95e-01 | 87.1% | 79.5% |
ECOD (56)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3867833 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.93 | 84.0 | 6.00e-01 | 94.0% | 38.6% |
| 3882204 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.92 | 87.0 | 6.02e-01 | 99.1% | 34.8% |
| 1503525 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.91 | 86.0 | 6.20e-01 | 99.1% | 39.5% |
| 3775772 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.91 | 87.0 | 6.09e-01 | 99.1% | 37.1% |
| 3899139 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.90 | 84.0 | 5.95e-01 | 99.1% | 37.0% |
| 3902178 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.90 | 86.0 | 6.02e-01 | 100.0% | 38.7% |
| None | — | 0.90 | 85.0 | 5.99e-01 | 99.1% | 37.1% | |
| 3571482 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.90 | 85.0 | 5.92e-01 | 99.1% | 35.9% |
| 3535009 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.89 | 85.0 | 5.93e-01 | 100.0% | 45.2% |
| 3904125 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.89 | 84.0 | 5.84e-01 | 99.1% | 35.8% |
| 3920784 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.88 | 81.0 | 5.53e-01 | 99.1% | 31.2% |
| 3855618 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.87 | 82.0 | 5.78e-01 | 99.1% | 36.9% |
| None | — | 0.87 | 82.0 | 5.88e-01 | 100.0% | 43.0% | |
| 3848908 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.86 | 81.0 | 5.65e-01 | 99.1% | 35.5% |
| 3748911 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.86 | 81.0 | 5.53e-01 | 100.0% | 32.5% |
| 3912215 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.86 | 81.0 | 5.70e-01 | 100.0% | 36.3% |
| 3217875 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.83 | 78.0 | 5.36e-01 | 99.1% | 33.1% |
| 4857560 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.83 | 76.0 | 5.66e-01 | 99.1% | 41.5% |
| 4855949 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.83 | 77.0 | 6.67e-01 | 99.1% | 67.3% |
| 4877165 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.81 | 75.0 | 6.42e-01 | 99.1% | 65.0% |
| 5022893 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.79 | 65.0 | 5.38e-01 | 100.0% | 51.0% |
| 3994884 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.76 | 66.0 | 4.76e-01 | 99.1% | 34.8% |
| 3475961 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.75 | 69.0 | 4.75e-01 | 100.0% | 51.2% |
| 4216626 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.73 | 66.0 | 4.64e-01 | 99.1% | 45.2% |
| 3995294 | 1065.1.1.0 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain | 0.73 | 50.0 | 4.94e-01 | 70.7% | 67.2% |
| 4596937 | 605.1.1.247 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PCRF | 0.73 | 57.0 | 6.15e-01 | 83.6% | 100.0% |
| 3611632 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.72 | 48.0 | 5.15e-01 | 70.7% | 79.0% |
| 3752758 | 3755.3.1.467 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C | 0.71 | 49.0 | 4.54e-01 | 71.6% | 56.4% |
| 4054880 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.70 | 57.0 | 5.98e-01 | 86.2% | 100.0% |
| 4579811 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.70 | 55.0 | 5.79e-01 | 83.6% | 95.2% |
| 4303085 | 3755.3.1.467 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DRC7_C | 0.70 | 48.0 | 4.84e-01 | 71.6% | 70.0% |
| 3924838 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.70 | 64.0 | 4.99e-01 | 99.1% | 49.6% |
| 3185197 | 192.5.1.17 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › DUF202 | 0.69 | 56.0 | 5.39e-01 | 100.0% | 76.3% |
| 3906631 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.68 | 56.0 | 5.74e-01 | 87.1% | 95.5% |
| 3962352 | 192.29.1.146 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF2231 | 0.68 | 60.0 | 5.47e-01 | 100.0% | 73.2% |
| 3659035 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.68 | 60.0 | 5.24e-01 | 98.3% | 67.0% |
| 5025122 | 3932.1.1.0 ↗ | alpha bundles › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain | 0.68 | 41.0 | 4.43e-01 | 94.8% | 71.6% |
| 3231243 | 4177.1.1.10 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH | 0.67 | 61.0 | 4.55e-01 | 100.0% | 80.0% |
| 3240858 | 5001.1.1.35 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srsx | 0.67 | 60.0 | 4.44e-01 | 98.3% | 70.0% |
| 3207663 | 605.4.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › DUF202 | 0.66 | 52.0 | 5.42e-01 | 100.0% | 93.5% |
| 3477269 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.65 | 45.0 | 4.12e-01 | 70.7% | 84.5% |
| 3591771 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.64 | 56.0 | 5.22e-01 | 100.0% | 78.0% |
| 3894262 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.63 | 57.0 | 4.21e-01 | 100.0% | 73.1% |
| 3912641 | 1203.1.2.1 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 | 0.63 | 56.0 | 4.47e-01 | 100.0% | 72.2% |
| 3449357 | 150.1.1.110 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF7358 | 0.62 | 53.0 | 4.75e-01 | 96.6% | 71.8% |
| 3750261 | 192.8.1.421 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › DUF4745 | 0.62 | 56.0 | 5.34e-01 | 100.0% | 94.1% |
| 4602773 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.61 | 52.0 | 4.94e-01 | 100.0% | 78.5% |
| 3732232 | 109.3.1.293 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ran-binding | 0.60 | 53.0 | 4.85e-01 | 97.4% | 83.2% |
| 4977923 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.59 | 46.0 | 4.19e-01 | 85.3% | 89.4% |
| 4848262 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.58 | 41.0 | 4.27e-01 | 72.4% | 86.0% |
| 4426096 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.57 | 49.0 | 4.79e-01 | 100.0% | 95.4% |
| 4982292 | 5045.1.1.0 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A | 0.57 | 47.0 | 3.87e-01 | 92.2% | 82.7% |
| 3829240 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.56 | 48.0 | 4.83e-01 | 100.0% | 96.7% |
| 3839810 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.56 | 48.0 | 4.58e-01 | 100.0% | 81.4% |
| 3678718 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.54 | 45.0 | 4.66e-01 | 96.6% | 100.0% |
| 3484694 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.53 | 46.0 | 3.40e-01 | 99.1% | 84.8% |