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ORF78

Euk-Vir

Ranid_herpesvirus_2

ORF78__YP_656586__Ranid_herpesvirus_2__389214

Identity

Accession:
YP_656586 ↗
Protein ID:
ORF78
Kingdom:
euk

Quality

62.8 mean pLDDT

Taxonomy

Heunggongvirae› Peploviricota› Herviviricetes› Herpesvirales› Alloherpesviridae› Batravirus› Ranid_herpesvirus_2

TaxID: 389214

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 76-109_169-195_277-352
PDB
Domain cluster: representative
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3612587 4357.1.1.0 ↗ beta barrels › WWE domain › WWE domain › WWE domain 0.76 23.0 3.56e-01 70.8% 63.3%
3479225 216.1.1.0 ↗ a+b two layers › UBC-like › UBC-like › UBC-like 0.58 25.0 2.87e-01 74.5% 52.0%
D2 medium residues 110-168
PDB
Domain cluster: representative
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3veaA02 1.10.1220.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant › Met repressor-like 0.68 45.0 4.76e-01 79.7% 78.8%
1z72A00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.67 48.0 3.23e-01 76.3% 48.1%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.63 49.0 4.20e-01 88.1% 62.6%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.62 51.0 4.13e-01 89.8% 55.5%
5tl8A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.60 48.0 2.86e-01 88.1% 32.0%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.59 42.0 4.31e-01 91.5% 79.3%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.57 47.0 3.65e-01 100.0% 66.2%
2b5dX01 3.20.110.10 Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain 0.57 46.0 2.90e-01 98.3% 24.0%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 44.0 3.75e-01 88.1% 70.6%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.56 42.0 3.92e-01 96.6% 63.3%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.55 38.0 3.66e-01 79.7% 60.8%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.54 41.0 3.81e-01 88.1% 66.7%
3cx5A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.54 46.0 3.13e-01 96.6% 48.0%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.54 47.0 4.54e-01 98.3% 87.7%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3660913 3826.1.1.0 ↗ alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.74 58.0 5.13e-01 88.1% 77.8%
3619662 192.12.1.3 ↗ alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM › DUF747 0.64 47.0 4.25e-01 78.0% 71.2%
5040824 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.58 48.0 3.69e-01 100.0% 40.3%
3366776 109.4.1.1690 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_17, TPR_16 0.57 45.0 3.19e-01 100.0% 25.6%
3709619 1008.1.1.0 ↗ alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain 0.54 40.0 3.65e-01 83.1% 83.5%
3516675 5059.1.1.5 ↗ alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › UAA 0.51 43.0 2.84e-01 100.0% 24.3%
D3 medium residues 196-276
PDB
Domain cluster: representative
CATH (26)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3zbhA00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.70 42.0 4.09e-01 100.0% 53.3%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.65 39.0 3.87e-01 100.0% 56.6%
3zh9B03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.65 51.0 4.45e-01 86.4% 88.9%
3rh3A01 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.65 41.0 3.47e-01 100.0% 39.1%
2el7A02 1.10.240.10 Mainly Alpha › Orthogonal Bundle › Tyrosyl-Transfer RNA Synthetase › Tyrosyl-Transfer RNA Synthetase 0.63 45.0 4.37e-01 91.4% 66.0%
2i2xB01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.63 38.0 3.55e-01 100.0% 49.0%
1r3dA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.63 53.0 3.77e-01 95.1% 39.3%
2np5D00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 44.0 3.61e-01 76.5% 90.5%
3f1bA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 42.0 3.37e-01 75.3% 89.1%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.60 40.0 2.66e-01 100.0% 17.8%
5z7cA01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.60 41.0 3.23e-01 71.6% 80.7%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.60 42.0 4.58e-01 100.0% 88.1%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.59 46.0 4.03e-01 85.2% 89.7%
2avuB00 1.10.4000.10 Mainly Alpha › Orthogonal Bundle › Flagellar transcriptional activator fold › Flagellar transcriptional activator FlhD 0.59 41.0 3.84e-01 72.8% 100.0%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.58 40.0 3.88e-01 100.0% 63.3%
4u04A02 1.10.3290.10 Mainly Alpha › Orthogonal Bundle › Fic-like fold › Fido-like domain 0.58 49.0 3.58e-01 93.8% 49.8%
2gl2B00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 38.0 3.45e-01 100.0% 50.5%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.56 44.0 4.03e-01 100.0% 63.6%
3hv0A02 1.10.240.10 Mainly Alpha › Orthogonal Bundle › Tyrosyl-Transfer RNA Synthetase › Tyrosyl-Transfer RNA Synthetase 0.56 46.0 4.21e-01 95.1% 67.9%
2jqqA00 1.20.58.1240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 38.0 3.14e-01 100.0% 37.7%
3r84B00 6.10.280.160 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 0.55 41.0 4.22e-01 98.8% 81.2%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.54 43.0 3.10e-01 100.0% 31.9%
3zhiA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.53 35.0 3.65e-01 84.0% 74.0%
3nuqA01 1.10.150.450 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.52 43.0 4.07e-01 92.6% 88.9%
3cucA00 1.10.3290.10 Mainly Alpha › Orthogonal Bundle › Fic-like fold › Fido-like domain 0.52 43.0 3.20e-01 100.0% 60.7%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.51 41.0 3.88e-01 100.0% 70.7%
ECOD (23)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4499545 604.9.1.20 ↗ alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › TMD_POM152 0.69 44.0 4.12e-01 100.0% 53.0%
4311347 604.24.1.0 ↗ alpha bundles › Spectrin repeat-like › Helical bundle domain in putative transcriptional regulator Jann_0659-related proteins › Helical bundle domain in putative transcriptional regulator Jann_0659-related proteins 0.68 40.0 4.11e-01 100.0% 60.0%
3588615 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 43.0 4.22e-01 100.0% 58.9%
3192128 604.12.1.71 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › TMD_POM152 0.67 43.0 3.98e-01 100.0% 50.5%
4011489 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.67 43.0 4.18e-01 100.0% 58.9%
3529707 4.1.1.453 ↗ beta barrels › SH3 › SH3 › SH3 › HR1_TOCA 0.64 40.0 3.82e-01 100.0% 54.7%
1180363 4995.1.1.1 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.63 39.0 4.09e-01 100.0% 70.4%
4934610 632.11.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.62 38.0 3.75e-01 100.0% 57.6%
3193004 604.13.1.0 ↗ alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like 0.61 40.0 3.63e-01 100.0% 49.1%
3602208 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.60 41.0 3.72e-01 98.8% 51.8%
5070669 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.60 42.0 3.18e-01 74.1% 73.0%
3807085 604.3.1.1 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.57 39.0 3.85e-01 98.8% 65.9%
3599480 5050.1.1.0 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.57 51.0 3.71e-01 100.0% 56.0%
4012148 604.13.1.0 ↗ alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like 0.57 37.0 3.37e-01 100.0% 47.0%
3924662 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 38.0 3.66e-01 98.8% 58.9%
1019364 604.5.1.2 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.56 44.0 3.98e-01 100.0% 61.3%
3974274 7579.1.1.6 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.55 45.0 3.20e-01 93.8% 35.1%
4936312 604.5.1.2 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.54 43.0 3.85e-01 100.0% 61.8%
5048093 192.7.1.2 ↗ alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.54 41.0 3.67e-01 100.0% 59.1%
3892500 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.53 41.0 3.73e-01 100.0% 60.9%
3968882 7579.1.1.6 ↗ a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 0.53 43.0 2.99e-01 93.8% 34.1%
5080181 601.28.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.50 40.0 3.73e-01 86.4% 88.6%
5008560 4995.1.1.1 ↗ alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.50 37.0 3.40e-01 79.0% 60.0%
D4 medium residues 564-651
PDB