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ORF8_protein
Euk-VirSimian_hemorrhagic_encephalitis_virus
ORF8_protein__YP_009505579__Simian_hemorrhagic_encephalitis_virus__1965068
Identity
- Accession:
- YP_009505579 ↗
- Protein ID:
- ORF8_protein
- Kingdom:
- euk
Quality
63.0
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Pisoniviricetes›
Nidovirales›
Arteriviridae›
Epsilonarterivirus›
Simian_hemorrhagic_encephalitis_virus
TaxID: 1965068
Cluster
View cluster (13 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 9-87
Domain cluster:
representative
CATH (77)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.90 | 63.0 | 4.30e-01 | 73.4% | 24.2% |
| 4abmD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.89 | 63.0 | 6.46e-01 | 73.4% | 76.6% |
| 4wpeA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.87 | 60.0 | 3.97e-01 | 73.4% | 20.4% |
| 3bt5A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.87 | 60.0 | 4.70e-01 | 73.4% | 37.1% |
| 1ij5A01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.86 | 57.0 | 5.89e-01 | 72.2% | 71.1% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.86 | 61.0 | 5.92e-01 | 73.4% | 94.3% |
| 3na7A00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.86 | 60.0 | 4.13e-01 | 73.4% | 24.1% |
| 1wp7A00 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.85 | 57.0 | 6.29e-01 | 70.9% | 84.4% |
| 6vq6G02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.85 | 67.0 | 4.95e-01 | 82.3% | 60.9% |
| 1urfA00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.85 | 60.0 | 6.02e-01 | 73.4% | 76.5% |
| 2ch7A00 | 1.10.287.950 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein | 0.84 | 60.0 | 3.87e-01 | 73.4% | 96.4% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.84 | 60.0 | 4.41e-01 | 73.4% | 95.6% |
| 1ykhA00 | 6.10.140.200 | Special › Helix non-globular › Helix Hairpins › | 0.83 | 59.0 | 5.53e-01 | 73.4% | 61.1% |
| 4g80T00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.83 | 60.0 | 4.87e-01 | 74.7% | 42.4% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.83 | 58.0 | 6.36e-01 | 73.4% | 89.1% |
| 3qkyA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.82 | 71.0 | 4.88e-01 | 97.5% | 29.5% |
| 3mq1A01 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.81 | 65.0 | 6.15e-01 | 84.8% | 96.7% |
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.81 | 57.0 | 6.40e-01 | 73.4% | 95.1% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.80 | 57.0 | 5.67e-01 | 73.4% | 98.8% |
| 1aj3A00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 66.0 | 6.18e-01 | 89.9% | 99.0% |
| 3fnbA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.80 | 61.0 | 5.39e-01 | 81.0% | 61.4% |
| 2b5uA02 | 1.10.287.620 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins | 0.80 | 56.0 | 4.41e-01 | 73.4% | 75.2% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.80 | 56.0 | 4.47e-01 | 72.2% | 50.3% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 72.0 | 5.74e-01 | 98.7% | 53.9% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.80 | 56.0 | 4.88e-01 | 73.4% | 52.5% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.80 | 71.0 | 6.57e-01 | 96.2% | 80.4% |
| 2efkA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.78 | 55.0 | 3.79e-01 | 73.4% | 22.1% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.78 | 55.0 | 4.67e-01 | 73.4% | 53.6% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.78 | 68.0 | 7.03e-01 | 93.7% | 100.0% |
| 7smtA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.78 | 70.0 | 5.38e-01 | 100.0% | 51.1% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.77 | 67.0 | 6.31e-01 | 92.4% | 79.6% |
| 1s5jA04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.77 | 52.0 | 5.85e-01 | 70.9% | 90.2% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.77 | 65.0 | 6.20e-01 | 89.9% | 92.3% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 67.0 | 6.09e-01 | 96.2% | 100.0% |
| 2b5dX01 | 3.20.110.10 | Alpha Beta › Alpha-Beta Barrel › 7-stranded beta/alpha barrel › Glycoside hydrolase 38, N terminal domain | 0.76 | 55.0 | 3.45e-01 | 75.9% | 23.5% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 63.0 | 5.83e-01 | 92.4% | 99.0% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.75 | 67.0 | 5.36e-01 | 96.2% | 63.9% |
| 1ugoA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.75 | 66.0 | 6.11e-01 | 96.2% | 85.9% |
| 1kt1A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.75 | 66.0 | 5.22e-01 | 96.2% | 65.8% |
| 4it4A02 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.75 | 67.0 | 6.42e-01 | 98.7% | 92.3% |
| 1xg2B00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.75 | 66.0 | 5.29e-01 | 96.2% | 60.9% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.75 | 65.0 | 6.28e-01 | 94.9% | 93.1% |
| 1ug7A00 | 1.20.120.360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain | 0.75 | 63.0 | 5.43e-01 | 94.9% | 62.5% |
| 2wdqD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.74 | 53.0 | 4.81e-01 | 74.7% | 69.5% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.74 | 51.0 | 5.19e-01 | 72.2% | 78.2% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.74 | 52.0 | 4.88e-01 | 73.4% | 92.7% |
| 3g80A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.74 | 50.0 | 5.24e-01 | 70.9% | 78.1% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 66.0 | 5.93e-01 | 100.0% | 98.1% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 60.0 | 6.17e-01 | 89.9% | 100.0% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.73 | 63.0 | 6.16e-01 | 94.9% | 95.3% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.73 | 64.0 | 5.64e-01 | 100.0% | 83.1% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.72 | 61.0 | 4.95e-01 | 92.4% | 51.4% |
| 4akgA04 | 1.20.58.1120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 | 0.72 | 63.0 | 4.96e-01 | 94.9% | 53.2% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.71 | 61.0 | 5.87e-01 | 97.5% | 97.8% |
| 6wv5A01 | 1.20.1440.130 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain | 0.71 | 60.0 | 5.07e-01 | 94.9% | 73.5% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.71 | 62.0 | 5.59e-01 | 98.7% | 100.0% |
| 2js5A00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.71 | 50.0 | 5.24e-01 | 74.7% | 83.1% |
| 5k3hB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.70 | 49.0 | 4.14e-01 | 73.4% | 46.6% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.70 | 60.0 | 5.62e-01 | 100.0% | 99.0% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.70 | 62.0 | 5.42e-01 | 98.7% | 99.1% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.69 | 55.0 | 4.91e-01 | 86.1% | 94.5% |
| 5dn6J00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.68 | 47.0 | 4.90e-01 | 72.2% | 83.8% |
| 2jbwA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.68 | 56.0 | 5.20e-01 | 92.4% | 70.9% |
| 3l9fA02 | 6.10.140.1570 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 51.0 | 5.10e-01 | 81.0% | 100.0% |
| 2b1eA04 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.68 | 57.0 | 5.00e-01 | 97.5% | 75.6% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.67 | 56.0 | 5.25e-01 | 93.7% | 77.8% |
| 5o5jT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.66 | 50.0 | 4.97e-01 | 87.3% | 78.8% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.64 | 46.0 | 4.71e-01 | 77.2% | 84.6% |
| 1blwC00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.64 | 53.0 | 4.43e-01 | 93.7% | 78.0% |
| 3mekA04 | 1.25.40.970 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.63 | 46.0 | 4.67e-01 | 84.8% | 78.8% |
| 2nrlA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.63 | 52.0 | 4.32e-01 | 92.4% | 95.9% |
| 2gsvA00 | 6.10.140.40 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 47.0 | 4.98e-01 | 81.0% | 98.5% |
| 3o39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.61 | 43.0 | 4.06e-01 | 73.4% | 67.7% |
| 1z9hA03 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 48.0 | 3.95e-01 | 88.6% | 82.1% |
| 5k29A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.60 | 50.0 | 4.71e-01 | 94.9% | 79.4% |
| 2mabA00 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.55 | 44.0 | 4.02e-01 | 89.9% | 84.4% |
| 1o3uA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.54 | 47.0 | 4.07e-01 | 93.7% | 84.2% |
ECOD (78)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3520468 | 4207.1.1.0 ↗ | alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) | 0.93 | 66.0 | 5.91e-01 | 73.4% | 55.2% |
| 3819961 | 3291.1.1.225 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › AAA_lid_At3g28540 | 0.92 | 68.0 | 5.54e-01 | 75.9% | 70.0% |
| 3184698 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.89 | 64.0 | 6.06e-01 | 73.4% | 65.6% |
| 4246573 | 3755.1.1.8 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › FliJ | 0.89 | 63.0 | 4.98e-01 | 73.4% | 77.3% |
| 3287947 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.88 | 62.0 | 5.89e-01 | 72.2% | 64.4% |
| 3386554 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.87 | 61.0 | 6.27e-01 | 72.2% | 77.3% |
| 3291377 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.87 | 60.0 | 5.65e-01 | 72.2% | 62.1% |
| 3661792 | 109.4.1.37 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 | 0.86 | 78.0 | 4.95e-01 | 97.5% | 86.8% |
| 3508180 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.85 | 63.0 | 4.04e-01 | 77.2% | 44.2% |
| 3574334 | 3755.3.1.72 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Myosin_tail_1 | 0.85 | 60.0 | 3.67e-01 | 73.4% | 13.2% |
| 3225714 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.85 | 78.0 | 6.17e-01 | 100.0% | 56.8% |
| 3663533 | 109.4.1.202 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_16 | 0.85 | 67.0 | 4.97e-01 | 83.5% | 36.8% |
| 3491689 | 604.1.1.159 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TMEM120A-B | 0.85 | 76.0 | 6.57e-01 | 97.5% | 98.3% |
| 3831168 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.85 | 73.0 | 5.94e-01 | 93.7% | 52.1% |
| 3229891 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.85 | 78.0 | 6.42e-01 | 100.0% | 64.4% |
| 4028957 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.85 | 79.0 | 6.05e-01 | 100.0% | 82.4% |
| 3233698 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.85 | 78.0 | 6.59e-01 | 100.0% | 69.6% |
| 3713565 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.84 | 75.0 | 5.62e-01 | 93.7% | 74.1% |
| 4836886 | 5057.1.1.1 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb | 0.84 | 75.0 | 7.29e-01 | 97.5% | 100.0% |
| 3665728 | 109.4.1.37 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 | 0.84 | 76.0 | 4.79e-01 | 97.5% | 87.8% |
| 3585081 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.83 | 76.0 | 6.38e-01 | 100.0% | 67.7% |
| 3501998 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.83 | 70.0 | 6.88e-01 | 89.9% | 90.6% |
| 3815122 | 604.12.1.68 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF6857 | 0.83 | 75.0 | 5.68e-01 | 98.7% | 76.7% |
| 3361591 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.83 | 68.0 | 5.74e-01 | 87.3% | 85.6% |
| 3508664 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.82 | 77.0 | 6.69e-01 | 100.0% | 76.5% |
| 3411108 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.82 | 76.0 | 6.27e-01 | 100.0% | 66.7% |
| 3432830 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.82 | 73.0 | 4.41e-01 | 94.9% | 20.5% |
| 3253634 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.82 | 76.0 | 6.84e-01 | 100.0% | 81.0% |
| 3637430 | 109.4.1.37 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 | 0.82 | 74.0 | 4.69e-01 | 97.5% | 84.9% |
| 3374084 | 604.1.1.61 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF6857 | 0.82 | 76.0 | 5.55e-01 | 100.0% | 53.8% |
| 3425354 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.82 | 67.0 | 4.78e-01 | 87.3% | 91.6% |
| 3430567 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.81 | 57.0 | 6.39e-01 | 72.2% | 100.0% |
| 3782297 | 109.4.1.37 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BRO1 | 0.81 | 73.0 | 4.60e-01 | 97.5% | 87.3% |
| 3927597 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.81 | 71.0 | 6.11e-01 | 94.9% | 89.2% |
| 3245544 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.81 | 73.0 | 6.42e-01 | 98.7% | 87.0% |
| 3412019 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.81 | 56.0 | 5.33e-01 | 72.2% | 62.2% |
| 3366463 | 622.4.1.36 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › DUF6857 | 0.81 | 74.0 | 5.48e-01 | 100.0% | 45.0% |
| 3715891 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.81 | 57.0 | 4.42e-01 | 73.4% | 86.1% |
| 4362562 | 148.1.3.337 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › PF27734 | 0.80 | 56.0 | 4.09e-01 | 72.2% | 41.0% |
| 3792037 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.80 | 73.0 | 5.78e-01 | 100.0% | 58.7% |
| 3824114 | 604.6.1.24 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › DUF6857 | 0.80 | 70.0 | 5.87e-01 | 94.9% | 98.5% |
| 3573589 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.79 | 55.0 | 5.08e-01 | 72.2% | 64.0% |
| 3500905 | 604.13.1.1 ↗ | alpha bundles › Spectrin repeat-like › USP8 N-terminal domain-like › USP8 N-terminal domain-like › USP8_dimer | 0.79 | 72.0 | 6.09e-01 | 98.7% | 70.4% |
| 3803172 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.79 | 72.0 | 5.59e-01 | 97.5% | 60.6% |
| 3592177 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.79 | 63.0 | 6.69e-01 | 84.8% | 100.0% |
| 3388493 | 633.10.1.15 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 | 0.78 | 71.0 | 5.91e-01 | 97.5% | 78.5% |
| 3724935 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.78 | 70.0 | 5.72e-01 | 100.0% | 90.3% |
| 3607681 | 633.10.1.15 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 | 0.78 | 71.0 | 5.91e-01 | 100.0% | 77.0% |
| 3924801 | 109.4.1.1643 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RSLD_CPSF6 | 0.78 | 69.0 | 6.53e-01 | 100.0% | 85.3% |
| 3993029 | 604.12.1.8 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › KATNA1_MIT | 0.78 | 70.0 | 6.58e-01 | 97.5% | 88.4% |
| 3773905 | 604.3.1.33 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › RSLD_CPSF6 | 0.77 | 67.0 | 6.93e-01 | 93.7% | 100.0% |
| 4649114 | 3559.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 | 0.77 | 54.0 | 5.00e-01 | 73.4% | 61.0% |
| 3502219 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.77 | 65.0 | 5.97e-01 | 94.9% | 75.2% |
| 3740949 | 604.12.1.47 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › V-SNARE_C | 0.76 | 67.0 | 5.46e-01 | 97.5% | 55.2% |
| 5024482 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.76 | 66.0 | 5.16e-01 | 96.2% | 45.3% |
| 3629501 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.76 | 70.0 | 4.35e-01 | 100.0% | 19.4% |
| 3424090 | 109.4.1.362 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_8 | 0.76 | 69.0 | 5.13e-01 | 98.7% | 88.9% |
| 3229748 | 1134.1.1.9 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › RSLD_CPSF6 | 0.76 | 67.0 | 6.60e-01 | 100.0% | 91.8% |
| 4342803 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.76 | 68.0 | 6.09e-01 | 100.0% | 86.4% |
| 3935140 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.75 | 53.0 | 4.02e-01 | 73.4% | 45.0% |
| 3629701 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.75 | 66.0 | 6.45e-01 | 97.5% | 95.3% |
| 4978412 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.75 | 70.0 | 5.25e-01 | 100.0% | 86.3% |
| 3827313 | 633.4.1.0 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor | 0.75 | 63.0 | 5.62e-01 | 91.1% | 77.3% |
| 3935633 | 1203.1.2.1 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ASD2 | 0.74 | 52.0 | 3.95e-01 | 73.4% | 35.1% |
| 3520922 | 109.4.1.1366 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DOCK_C-D_N, PF28208 | 0.73 | 60.0 | 3.43e-01 | 89.9% | 9.8% |
| 3737161 | 3559.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 | 0.72 | 51.0 | 4.56e-01 | 73.4% | 68.2% |
| 4030302 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.72 | 62.0 | 5.19e-01 | 94.9% | 87.4% |
| 3286501 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 55.0 | 4.51e-01 | 91.1% | 45.5% |
| 4324180 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.71 | 48.0 | 4.50e-01 | 70.9% | 63.0% |
| 4647835 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.70 | 60.0 | 4.29e-01 | 94.9% | 87.0% |
| 3177985 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.70 | 57.0 | 3.95e-01 | 88.6% | 72.5% |
| 4994917 | 3834.1.1.25 ↗ | alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain › DUF7121 | 0.68 | 46.0 | 3.29e-01 | 70.9% | 100.0% |
| 3923557 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.67 | 47.0 | 3.55e-01 | 73.4% | 34.0% |
| 4068116 | 5060.1.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C › vATP-synt_AC39 | 0.67 | 57.0 | 5.09e-01 | 97.5% | 93.0% |
| 4106453 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.62 | 44.0 | 3.98e-01 | 73.4% | 60.0% |
| 3369128 | 2004.1.1.615 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23, AAA_29 | 0.62 | 48.0 | 2.87e-01 | 88.6% | 11.9% |
| 3265113 | 593.1.1.0 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like | 0.61 | 49.0 | 3.42e-01 | 91.1% | 43.0% |
| None | — | 0.61 | 52.0 | 3.89e-01 | 97.5% | 72.9% |
D2
high
residues 97-146