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ORF9

Euk-Vir

Macaca_nemestrina_rhadinovirus_2

ORF9__YP_010084549__Macaca_nemestrina_rhadinovirus_2__123630

Identity

Accession:
YP_010084549 ↗
Protein ID:
ORF9
Kingdom:
euk

Quality

86.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 292-533
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03104.26 best DNA_pol_B_exo1 169.6 1.10e-49 70.7% 74.4%
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3iayA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.91 79.0 8.45e-01 91.3% 100.0%
1d5aA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.91 78.0 8.28e-01 100.0% 98.2%
1q8iA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.91 68.0 7.86e-01 90.5% 100.0%
2gv9A03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.91 81.0 8.49e-01 90.5% 100.0%
1s5jA02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.84 66.0 7.43e-01 88.8% 100.0%
4qclA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.82 79.0 7.61e-01 100.0% 89.3%
4fvmA03 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.81 72.0 7.35e-01 91.3% 99.6%
1noyB02 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.80 71.0 7.40e-01 91.3% 100.0%
2p1jA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.76 43.0 5.84e-01 72.7% 100.0%
1x9mA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.64 55.0 5.70e-01 98.8% 94.2%
1wcwA01 3.40.50.10090 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 32.0 4.32e-01 95.9% 100.0%
2hqbA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.54 29.0 3.78e-01 99.6% 93.9%
3l6uA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.51 28.0 3.62e-01 100.0% 96.0%
1ofuX00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 26.0 3.49e-01 98.3% 94.1%
1gsoA01 3.40.50.20 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.50 23.0 3.29e-01 99.2% 100.0%
ECOD (99)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4972474 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.95 87.0 5.99e-01 100.0% 33.6%
5017082 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.94 80.0 6.79e-01 100.0% 58.9%
5081878 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.94 76.0 6.41e-01 100.0% 55.0%
5025208 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.94 77.0 7.92e-01 100.0% 87.8%
4981192 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.93 77.0 7.58e-01 100.0% 80.0%
4504110 2484.1.1.197 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 0.93 81.0 6.50e-01 100.0% 51.8%
5069333 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.93 76.0 6.35e-01 100.0% 53.9%
3558197 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.92 87.0 8.73e-01 98.3% 95.9%
4282509 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.92 79.0 5.77e-01 100.0% 37.7%
5056578 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.92 81.0 7.46e-01 100.0% 73.9%
4452101 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.92 79.0 8.33e-01 100.0% 96.8%
4953654 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.92 81.0 7.06e-01 100.0% 64.4%
2801086 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.92 79.0 6.71e-01 100.0% 59.2%
1822623 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.92 90.0 8.54e-01 100.0% 89.1%
3368695 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.91 89.0 7.28e-01 100.0% 61.5%
4492006 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.91 74.0 7.06e-01 100.0% 73.7%
3628202 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.91 89.0 6.15e-01 100.0% 36.2%
None 0.91 88.0 6.20e-01 100.0% 37.8%
4939488 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.91 77.0 7.14e-01 100.0% 72.1%
5019480 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.91 85.0 5.74e-01 100.0% 31.7%
None 0.91 88.0 6.17e-01 100.0% 37.5%
None 0.91 89.0 7.48e-01 100.0% 66.3%
5005285 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.91 85.0 8.65e-01 100.0% 98.3%
4022366 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.91 87.0 6.15e-01 100.0% 37.6%
3710418 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.91 88.0 7.38e-01 100.0% 64.5%
4932479 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.91 79.0 7.21e-01 100.0% 71.1%
4502019 2484.1.1.197 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 0.91 80.0 6.42e-01 100.0% 52.5%
5067181 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.90 81.0 6.53e-01 100.0% 53.7%
4942685 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.90 81.0 6.17e-01 100.0% 45.8%
4891100 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.90 83.0 7.97e-01 97.9% 84.7%
5029084 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.90 80.0 8.29e-01 100.0% 97.3%
5036329 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.90 74.0 7.51e-01 100.0% 86.0%
5023018 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.90 76.0 8.14e-01 90.1% 99.0%
5035328 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.90 78.0 7.91e-01 100.0% 91.1%
5076410 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.90 75.0 6.29e-01 100.0% 55.7%
5043498 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.90 76.0 6.25e-01 100.0% 53.6%
5068716 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.89 77.0 6.82e-01 100.0% 66.6%
4990754 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.89 74.0 7.74e-01 100.0% 92.0%
4805117 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.89 59.0 6.26e-01 74.8% 74.1%
4982659 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.88 73.0 6.26e-01 100.0% 58.0%
3206356 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.88 85.0 6.96e-01 100.0% 63.7%
5054032 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.88 77.0 6.48e-01 99.6% 58.9%
3684974 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.88 84.0 5.92e-01 100.0% 38.5%
4023334 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.87 84.0 7.93e-01 100.0% 91.1%
4500300 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.87 72.0 6.03e-01 100.0% 53.5%
3683989 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.87 73.0 7.91e-01 100.0% 99.5%
3802227 2484.1.1.197 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 0.87 80.0 5.21e-01 100.0% 26.7%
None 0.87 79.0 5.21e-01 100.0% 27.2%
None 0.87 79.0 5.23e-01 99.6% 28.2%
4649118 2484.1.1.197 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 0.87 79.0 6.50e-01 100.0% 57.5%
3798596 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.86 78.0 8.15e-01 99.2% 99.6%
3619240 304.48.1.59 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_exo1, DNA_pol_B_exo2 0.86 79.0 5.31e-01 100.0% 29.9%
3784398 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.86 83.0 8.19e-01 100.0% 98.4%
3584771 2484.1.1.197 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, DNA_pol_B_exo2 0.86 79.0 7.28e-01 100.0% 76.9%
3825992 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.86 83.0 8.28e-01 100.0% 98.0%
3266685 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.86 78.0 4.82e-01 100.0% 19.6%
3168836 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.86 83.0 8.11e-01 100.0% 98.8%
4888481 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.85 73.0 7.03e-01 88.0% 79.7%
3404726 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.85 82.0 7.58e-01 100.0% 84.7%
3683241 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.85 82.0 7.34e-01 100.0% 82.8%
3466667 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.85 82.0 5.78e-01 100.0% 40.8%
3797773 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.85 82.0 7.56e-01 100.0% 84.4%
3794217 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.84 81.0 6.07e-01 100.0% 47.0%
3214818 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.84 79.0 6.64e-01 100.0% 62.7%
4029124 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.84 77.0 7.42e-01 98.3% 86.4%
3192875 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.84 80.0 6.16e-01 100.0% 49.5%
4988803 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.84 82.0 6.69e-01 100.0% 84.3%
3932596 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.84 79.0 8.01e-01 99.2% 100.0%
3705562 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.83 80.0 5.59e-01 100.0% 36.6%
3471270 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.83 76.0 6.91e-01 96.7% 73.9%
4944521 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.83 70.0 7.52e-01 90.5% 99.0%
4932453 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.83 80.0 7.17e-01 100.0% 80.9%
1790898 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.83 79.0 7.55e-01 100.0% 88.2%
3167764 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.83 80.0 7.26e-01 100.0% 83.9%
4323378 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.83 80.0 7.43e-01 100.0% 87.2%
3692564 2.1.1.25 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 0.82 79.0 6.47e-01 100.0% 61.7%
4874454 2.1.1.25 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DNA_pol_B_exo1 0.82 79.0 7.60e-01 100.0% 90.2%
3256261 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.82 78.0 7.62e-01 99.6% 92.5%
3193111 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.82 79.0 6.62e-01 100.0% 67.4%
5044376 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.82 54.0 4.78e-01 100.0% 48.9%
3496492 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.82 79.0 7.36e-01 100.0% 85.9%
3492151 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.82 79.0 6.97e-01 100.0% 84.5%
3702504 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.82 79.0 7.26e-01 100.0% 86.8%
3606428 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.82 77.0 7.82e-01 98.8% 100.0%
4218318 2484.1.1.295 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1, RNase_H_2 0.82 74.0 6.58e-01 100.0% 70.3%
11143 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.81 78.0 6.57e-01 100.0% 67.7%
3605750 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.81 79.0 5.08e-01 100.0% 41.9%
4958553 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.81 72.0 7.55e-01 91.7% 100.0%
2958185 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.80 77.0 7.30e-01 100.0% 90.4%
5070158 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.80 51.0 4.47e-01 100.0% 45.0%
4024811 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.80 77.0 7.25e-01 100.0% 91.8%
5035011 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.79 52.0 5.29e-01 100.0% 67.2%
5028571 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.79 73.0 7.02e-01 100.0% 85.9%
4966854 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.78 76.0 6.47e-01 100.0% 87.8%
4972218 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.77 75.0 5.66e-01 100.0% 71.0%
5076614 2484.1.1.328 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B 0.77 75.0 5.28e-01 100.0% 55.7%
3614440 2484.1.1.177 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF2779 0.74 58.0 6.17e-01 91.3% 89.0%
3719024 2484.1.1.177 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF2779 0.69 60.0 6.09e-01 91.3% 91.2%
5073666 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.56 53.0 4.71e-01 100.0% 81.2%
D2 high residues 831-1003
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 115.4 4.30e-33 91.9% 31.8%
D3 medium residues 94-153_235-291
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03104.26 best DNA_pol_B_exo1 39.7 5.30e-10 53.8% 24.4%
D4 medium residues 154-234
PDB
CATH (75)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3k59A02 3.30.70.2250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › B family DNA polymerase, N domain, alpha/beta motif 0.80 62.0 6.78e-01 100.0% 100.0%
3ce8A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.72 60.0 5.88e-01 100.0% 83.1%
1nh8A03 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 54.0 5.93e-01 100.0% 97.0%
6gdxA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 62.0 5.68e-01 100.0% 72.9%
1j2vA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 62.0 5.78e-01 100.0% 77.2%
4bbyA05 3.30.300.330 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.71 64.0 5.78e-01 98.8% 86.1%
4y6iA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 61.0 5.66e-01 100.0% 76.7%
4qclA02 3.30.70.2820 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 62.0 5.59e-01 100.0% 86.5%
3tupA02 3.30.70.380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ferrodoxin-fold anticodon-binding domain 0.69 61.0 5.80e-01 98.8% 91.7%
4e98C00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 60.0 5.52e-01 100.0% 75.2%
3ahpA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.69 60.0 5.58e-01 100.0% 76.4%
4fvmA02 3.30.70.2820 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 60.0 5.58e-01 100.0% 85.4%
2vfrA04 3.30.70.2520 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 60.0 5.78e-01 100.0% 95.7%
3luyA03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.67 58.0 5.64e-01 100.0% 86.5%
1m5hA02 3.30.70.520 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 61.0 4.95e-01 100.0% 93.2%
2yweA03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.66 55.0 5.52e-01 100.0% 90.2%
4mt1A03 3.30.70.1320 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain like 0.66 59.0 5.59e-01 100.0% 94.9%
2rrnA01 3.30.70.2040 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 56.0 5.60e-01 100.0% 91.6%
2mq8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.66 59.0 5.30e-01 100.0% 81.2%
2ek0A00 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.66 47.0 4.60e-01 75.3% 95.6%
1khmA00 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.66 53.0 5.15e-01 92.6% 78.7%
3ramA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 59.0 5.21e-01 100.0% 90.7%
1bdfA01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.65 53.0 4.94e-01 91.4% 77.4%
7o4xA01 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 56.0 5.30e-01 100.0% 79.8%
3mgjA00 3.30.70.2690 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › LOR/SDH bifunctional enzyme, conserved domain 0.65 58.0 5.53e-01 100.0% 84.4%
4rx6D00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 56.0 5.17e-01 100.0% 78.5%
5b08A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 57.0 5.33e-01 100.0% 91.0%
4c98A02 3.30.70.1900 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 56.0 4.71e-01 97.5% 94.9%
3qjlA01 3.30.70.1890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 57.0 5.01e-01 100.0% 95.0%
2uvaG03 3.30.70.3320 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 57.0 5.21e-01 100.0% 79.6%
8c46A01 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 56.0 5.05e-01 100.0% 93.0%
2qndA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.63 53.0 5.37e-01 93.8% 93.8%
2gx8A02 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 54.0 5.16e-01 100.0% 84.8%
7oocE01 3.30.70.60 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S6/Translation elongation factor EF1B 0.63 55.0 5.46e-01 98.8% 97.6%
6urtA02 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 53.0 5.17e-01 93.8% 94.3%
2ql8A00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.63 51.0 4.26e-01 88.9% 60.0%
4mt1A06 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.63 55.0 5.13e-01 100.0% 94.1%
4noiA01 3.30.1360.10 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › RNA polymerase, RBP11-like subunit 0.62 52.0 4.80e-01 91.4% 75.7%
2ftrA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 55.0 5.09e-01 100.0% 90.3%
3icaB00 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.62 51.0 3.79e-01 90.1% 85.0%
3ue2A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 55.0 5.39e-01 100.0% 98.9%
4l3tA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.62 54.0 3.82e-01 100.0% 77.0%
5xzqF00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 54.0 5.06e-01 100.0% 91.3%
1o51A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 53.0 5.23e-01 100.0% 89.9%
1nbwA02 3.90.470.30 Alpha Beta › Alpha-Beta Complex › Ribosomal Protein L22; Chain A › Coenzyme B12-Dependent Enzyme linker domain 0.61 44.0 3.68e-01 75.3% 90.2%
2yq1C00 3.30.70.390 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Epstein Barr virus nuclear antigen-1, DNA-binding domain 0.61 55.0 4.68e-01 100.0% 62.6%
1rtzA00 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.61 53.0 4.39e-01 100.0% 57.9%
1dfaA03 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.61 44.0 4.22e-01 81.5% 65.3%
2ldyA01 3.30.70.1820 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › L1 transposable element, RRM domain 0.61 54.0 5.13e-01 100.0% 100.0%
4ewtA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 53.0 4.79e-01 100.0% 97.4%
3bdeB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 54.0 5.06e-01 100.0% 90.9%
6tmfM00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.61 54.0 5.06e-01 100.0% 95.1%
2ypyA00 3.30.70.390 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Epstein Barr virus nuclear antigen-1, DNA-binding domain 0.61 54.0 4.58e-01 100.0% 61.2%
2cz4A00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 53.0 4.99e-01 100.0% 82.8%
3k17A02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.60 55.0 4.55e-01 100.0% 97.9%
4mamB03 3.30.470.20 Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain 0.60 46.0 3.51e-01 97.5% 35.1%
3bb5A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 53.0 4.94e-01 100.0% 96.1%
3io1A02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 52.0 4.70e-01 100.0% 91.4%
4cyuA00 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.60 52.0 4.29e-01 100.0% 60.4%
3iabB01 3.30.110.20 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › Alba-like domain 0.59 41.0 3.91e-01 74.1% 59.6%
3bguA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 51.0 4.91e-01 100.0% 92.7%
2rilA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 51.0 4.91e-01 100.0% 89.5%
5xyiU00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.58 51.0 4.85e-01 100.0% 95.9%
2mdaA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.58 48.0 4.67e-01 100.0% 82.1%
1rjjA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 50.0 4.54e-01 100.0% 81.1%
1gupB01 3.30.428.10 Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like 0.57 47.0 3.70e-01 90.1% 66.5%
6qdwt00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.57 41.0 4.00e-01 77.8% 76.3%
2wyhA05 2.60.40.2210 Mainly Beta › Sandwich › Immunoglobulin-like › 0.56 50.0 4.25e-01 100.0% 76.1%
2xzmJ00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.56 49.0 4.55e-01 100.0% 92.4%
2gh9A01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.55 47.0 3.65e-01 95.1% 83.9%
3thiA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.53 44.0 3.59e-01 97.5% 92.0%
3bzwF00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.52 36.0 2.64e-01 71.6% 74.1%
2nrqA00 3.30.1440.10 Alpha Beta › 2-Layer Sandwich › 50s Ribosomal Protein L5; Chain: A, › Ribosomal protein L5 0.52 44.0 3.82e-01 100.0% 82.5%
1j0wB00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 30.0 2.84e-01 100.0% 46.6%
5ib9A01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.51 42.0 2.93e-01 92.6% 56.8%
ECOD (91)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3837425 3922.1.1.336 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › POL3_N 0.86 79.0 7.22e-01 100.0% 97.1%
3484070 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.85 79.0 7.30e-01 100.0% 98.0%
3784400 304.114.1.2 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.82 76.0 6.21e-01 100.0% 96.4%
3606423 304.114.1.2 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.81 75.0 6.70e-01 100.0% 95.5%
3731090 304.114.1.2 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.80 75.0 6.90e-01 100.0% 98.0%
3932594 304.114.1.2 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.80 73.0 6.79e-01 100.0% 99.0%
3661686 304.114.1.2 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.80 72.0 6.57e-01 98.8% 95.2%
3800859 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.78 72.0 5.31e-01 100.0% 48.5%
5041306 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.78 71.0 7.17e-01 100.0% 97.5%
3579169 304.114.1.2 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.78 71.0 6.63e-01 98.8% 96.0%
3450246 304.114.1.2 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › POL3_N 0.78 55.0 5.68e-01 72.8% 96.0%
3788812 304.114.1.6 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain › DNA_pol_B_exo1 0.75 70.0 4.86e-01 100.0% 35.0%
4928840 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.72 63.0 5.87e-01 100.0% 78.0%
4929491 304.5.1.13 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › DUF3574 0.72 65.0 5.85e-01 100.0% 84.4%
4629521 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.71 62.0 5.73e-01 100.0% 75.0%
5040667 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.71 62.0 5.74e-01 100.0% 75.7%
3956965 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.71 63.0 4.96e-01 100.0% 48.0%
5015958 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.71 62.0 5.69e-01 100.0% 75.0%
5038160 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.71 62.0 5.77e-01 100.0% 78.0%
4957224 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.71 61.0 5.76e-01 100.0% 78.0%
402134 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.71 62.0 5.47e-01 100.0% 66.9%
4944847 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.71 61.0 5.71e-01 100.0% 76.9%
4140821 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.71 61.0 5.63e-01 100.0% 74.3%
5000967 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.70 62.0 5.70e-01 100.0% 75.2%
4937786 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.70 61.0 5.69e-01 100.0% 78.0%
3702503 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.70 62.0 6.05e-01 100.0% 92.2%
5052024 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.69 62.0 6.16e-01 100.0% 97.6%
4959038 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.69 60.0 5.90e-01 93.8% 92.9%
4993856 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.69 53.0 4.80e-01 80.2% 62.9%
4630093 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.69 59.0 5.17e-01 95.1% 80.0%
3963977 304.162.1.0 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.69 60.0 5.96e-01 95.1% 95.3%
3729608 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.68 60.0 5.23e-01 100.0% 84.0%
4995222 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.68 55.0 5.65e-01 100.0% 94.7%
4940122 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.68 59.0 5.61e-01 100.0% 81.8%
3214238 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.68 59.0 5.49e-01 100.0% 77.1%
3784198 304.114.1.0 a+b two layers › Alpha-beta plaits › Family B DNA polymerase insertion domain › Family B DNA polymerase insertion domain 0.68 60.0 5.51e-01 100.0% 94.3%
5037829 304.5.1.3 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › CutA1 0.67 59.0 5.55e-01 100.0% 79.0%
3958843 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.67 60.0 5.54e-01 100.0% 89.5%
3915011 389.1.1.7 few secondary structure elements › EGF-like › EGF-related › EGF/Laminin › EGF_CA 0.67 59.0 4.78e-01 100.0% 50.6%
4150055 304.5.1.5 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › HisG_C 0.67 54.0 5.50e-01 100.0% 88.6%
3706885 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.67 62.0 5.69e-01 100.0% 80.0%
3271185 304.12.1.5 a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › MBTP1_N 0.67 60.0 5.71e-01 100.0% 97.9%
4337362 304.44.1.0 a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 0.66 60.0 5.57e-01 100.0% 95.0%
3702886 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.66 59.0 4.20e-01 100.0% 35.2%
3724748 304.4.1.11 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › EthD 0.66 59.0 5.17e-01 100.0% 89.2%
4201083 304.12.1.1 a+b two layers › Alpha-beta plaits › Ribosomal protein S6 › Ribosomal protein S6 › Ribosomal_S6 0.66 58.0 5.44e-01 100.0% 86.0%
3171153 304.9.1.163 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PF30026 0.65 58.0 5.57e-01 100.0% 92.6%
3269273 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.65 60.0 5.80e-01 100.0% 95.6%
3167609 4323.1.1.1 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.65 58.0 5.90e-01 100.0% 97.5%
3703942 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.65 60.0 5.44e-01 100.0% 77.1%
3350776 304.5.1.23 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › V_ATPase_I 0.65 57.0 5.81e-01 97.5% 97.5%
3522520 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.64 58.0 5.85e-01 98.8% 98.8%
3569962 4323.1.1.1 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.64 58.0 5.53e-01 100.0% 84.2%
3890375 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.64 59.0 5.94e-01 100.0% 100.0%
4928686 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.64 59.0 5.71e-01 100.0% 91.1%
3184391 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.64 58.0 5.23e-01 100.0% 72.7%
4515208 304.24.1.7 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › V_ATPase_I 0.64 58.0 5.13e-01 100.0% 69.6%
3555669 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.64 58.0 5.06e-01 100.0% 66.7%
3417210 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.64 59.0 5.70e-01 100.0% 92.2%
4451470 304.126.1.1 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.64 58.0 4.89e-01 100.0% 61.5%
3579336 304.5.1.23 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › V_ATPase_I 0.64 58.0 5.18e-01 100.0% 72.7%
5039865 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.64 56.0 5.24e-01 98.8% 87.0%
3178013 304.9.1.103 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › PF26763 0.63 56.0 5.28e-01 100.0% 100.0%
4945381 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.63 53.0 5.31e-01 100.0% 91.8%
3964728 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.63 55.0 5.26e-01 98.8% 90.5%
4105404 305.1.1.1 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L 0.62 51.0 4.58e-01 91.4% 69.6%
3483966 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.62 55.0 5.08e-01 100.0% 88.6%
3548897 327.11.2.24 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_12 0.62 53.0 4.61e-01 93.8% 66.7%
5188 304.4.1.17 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › MmlI 0.61 54.0 4.98e-01 100.0% 90.5%
4542034 304.45.1.1 a+b two layers › Alpha-beta plaits › 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK › 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK › HPPK 0.61 53.0 4.50e-01 100.0% 68.6%
3956950 304.51.1.7 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR_Cas6 0.61 54.0 4.54e-01 100.0% 90.0%
4028387 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.61 53.0 5.08e-01 100.0% 86.3%
3178082 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.60 55.0 4.73e-01 100.0% 81.6%
3694783 327.16.1.0 a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system 0.60 52.0 4.19e-01 100.0% 80.0%
3177336 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.60 53.0 4.93e-01 100.0% 78.1%
4541115 305.1.1.1 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L 0.60 51.0 4.45e-01 95.1% 77.6%
4134590 304.4.1.11 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › EthD 0.60 53.0 4.96e-01 100.0% 91.0%
4223323 304.44.1.2 a+b two layers › Alpha-beta plaits › Ribosomal protein S10 › Ribosomal protein S10 › PriA_C 0.60 51.0 4.99e-01 98.8% 97.8%
3664706 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.59 52.0 5.12e-01 100.0% 90.6%
3685983 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.59 50.0 3.64e-01 100.0% 32.0%
4997569 304.4.1.10 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › DUF1330 0.59 52.0 4.94e-01 100.0% 94.7%
3912477 5001.1.1.5 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.58 45.0 3.06e-01 84.0% 78.1%
5058931 304.25.1.0 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.58 51.0 4.80e-01 100.0% 91.0%
4463387 304.5.1.18 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › PrmA 0.58 51.0 4.75e-01 100.0% 84.8%
3280665 304.4.1.10 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › DUF1330 0.58 51.0 4.66e-01 100.0% 81.8%
5002717 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.57 48.0 4.52e-01 95.1% 86.0%
4884496 304.116.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in release factor › Ferredoxin-like domain in release factor 0.56 48.0 4.54e-01 100.0% 96.1%
4309280 304.51.1.7 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR_Cas6 0.54 46.0 3.98e-01 97.5% 93.3%
4972140 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.54 45.0 3.70e-01 100.0% 50.0%
4945568 242.1.1.0 a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases 0.50 42.0 3.50e-01 100.0% 52.4%
3762934 882.1.1.1 a+b two layers › Ribosomal protein L5 › Ribosomal protein L5 › Ribosomal protein L5 › Ribosomal_L5 0.50 43.0 3.56e-01 100.0% 67.5%
D5 medium residues 541-568_593-708
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 148.1 5.20e-43 80.6% 25.2%
CATH (36)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2a26B01 4.10.860.10 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain 0.92 28.0 5.73e-01 82.6% 100.0%
2gv9B04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.88 34.0 3.01e-01 80.6% 27.9%
4fxdA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.86 67.0 6.58e-01 100.0% 75.8%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.85 30.0 5.52e-01 89.6% 100.0%
3fxdB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.84 34.0 5.66e-01 83.3% 100.0%
2rpaA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.82 35.0 4.80e-01 95.8% 76.6%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 37.0 5.37e-01 74.3% 90.4%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.80 34.0 4.77e-01 97.9% 78.7%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.78 37.0 4.50e-01 97.2% 68.0%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.78 36.0 4.72e-01 76.4% 76.5%
2cazC00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.75 32.0 4.89e-01 87.5% 93.8%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 39.0 4.68e-01 99.3% 74.5%
3vkgB03 1.20.58.1120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dynein motor heavy chain, linker domain, subdomain 4 0.73 42.0 4.08e-01 95.8% 52.6%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.73 38.0 5.18e-01 97.2% 96.1%
3a8pA02 6.10.140.680 Special › Helix non-globular › Helix Hairpins › 0.72 39.0 4.40e-01 89.6% 68.4%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 35.0 4.56e-01 98.6% 81.2%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.70 33.0 4.19e-01 89.6% 73.3%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.70 35.0 4.32e-01 99.3% 75.3%
1y6xA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.69 30.0 3.74e-01 90.3% 63.2%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.68 37.0 4.59e-01 95.8% 83.5%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 34.0 4.56e-01 75.0% 95.8%
3rm5B02 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.64 36.0 3.12e-01 97.2% 34.8%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 31.0 4.40e-01 70.8% 100.0%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.62 30.0 4.21e-01 70.8% 100.0%
1fxkB00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.61 37.0 4.29e-01 88.9% 80.7%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 38.0 3.29e-01 97.9% 42.8%
2o8pA00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.57 44.0 3.80e-01 97.2% 53.4%
5mmjn01 1.10.287.1480 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 27.0 3.35e-01 83.3% 74.2%
2wzkA01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.53 35.0 3.70e-01 100.0% 73.2%
6lw5A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 40.0 3.22e-01 80.6% 46.7%
1xioA00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 42.0 3.60e-01 82.6% 87.1%
3bh1A02 1.20.1570.10 Mainly Alpha › Up-down Bundle › dip2346 fold › dip2346 domain like 0.52 32.0 3.84e-01 88.2% 89.1%
3caxA01 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.52 41.0 3.54e-01 82.6% 67.7%
2a07J00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 25.0 3.09e-01 97.9% 74.7%
2phcB01 3.30.1360.40 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.50 23.0 3.01e-01 77.1% 74.7%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.50 29.0 3.71e-01 79.2% 96.5%
ECOD (55)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3503933 192.14.1.1 alpha bundles › Long alpha-hairpin › Siah interacting protein N terminal domain-like › Siah interacting protein N terminal domain-like › Siah-Interact_N 0.94 30.0 5.93e-01 86.8% 100.0%
None 0.93 91.0 5.64e-01 100.0% 25.9%
3558196 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.93 91.0 6.93e-01 100.0% 57.5%
3628202 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.92 90.0 5.54e-01 100.0% 24.7%
3480546 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.92 78.0 6.09e-01 86.8% 58.9%
None 0.92 89.0 5.53e-01 100.0% 26.1%
3705562 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.91 88.0 5.44e-01 100.0% 30.4%
3684974 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.90 87.0 5.41e-01 100.0% 28.2%
3484036 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.90 74.0 5.75e-01 84.0% 59.6%
3615419 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.90 87.0 6.38e-01 100.0% 64.5%
3249106 192.6.1.0 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain 0.90 32.0 5.79e-01 81.9% 100.0%
3784383 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.90 86.0 6.13e-01 100.0% 51.4%
4022366 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.89 85.0 5.33e-01 100.0% 26.1%
5005286 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.87 84.0 6.31e-01 100.0% 54.1%
4972474 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.87 84.0 5.17e-01 100.0% 24.1%
3801150 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.86 74.0 5.63e-01 88.2% 50.5%
4029141 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.86 72.0 5.73e-01 86.1% 55.0%
5019480 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.86 83.0 5.07e-01 100.0% 22.8%
3089539 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.85 71.0 5.46e-01 86.1% 56.4%
4981193 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.84 81.0 6.46e-01 100.0% 60.0%
3414767 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.82 37.0 5.06e-01 96.5% 80.0%
3217585 1008.1.1.0 alpha bundles › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain › BRCC36 C-terminal helical domain 0.81 38.0 4.81e-01 89.6% 73.3%
3290879 3922.1.1.155 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF4349 0.80 36.0 5.38e-01 72.9% 92.9%
3770100 604.12.1.8 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › KATNA1_MIT 0.80 37.0 4.74e-01 98.6% 73.3%
3264401 6132.1.1.0 alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain 0.79 35.0 4.85e-01 71.5% 81.3%
3480097 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.79 37.0 5.40e-01 97.9% 94.3%
3358885 604.12.1.8 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › KATNA1_MIT 0.79 37.0 5.02e-01 98.6% 82.5%
5025209 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.79 68.0 5.58e-01 88.9% 57.9%
3597965 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.78 63.0 5.13e-01 83.3% 57.6%
4276636 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.78 75.0 5.51e-01 100.0% 62.1%
3629711 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.73 45.0 4.89e-01 99.3% 73.3%
3965569 150.1.1.183 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Transposase_20 0.73 38.0 3.50e-01 92.4% 41.1%
3684015 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.70 42.0 5.00e-01 88.2% 86.0%
4419515 150.1.1.59 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F 0.68 35.0 4.76e-01 79.2% 92.5%
3570403 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.66 40.0 4.27e-01 84.0% 69.6%
3504474 192.5.1.1 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 0.65 41.0 4.93e-01 100.0% 92.0%
3809724 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.65 41.0 4.15e-01 97.9% 65.0%
3922888 109.4.1.889 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_M 0.64 42.0 3.71e-01 97.9% 46.8%
3467886 192.6.1.5 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › RWP-RK 0.63 42.0 4.88e-01 82.6% 92.4%
3710098 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.62 41.0 4.45e-01 99.3% 77.6%
4165448 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.61 42.0 4.91e-01 79.9% 96.2%
3766400 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.61 43.0 4.92e-01 99.3% 94.5%
4272021 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.61 41.0 4.95e-01 78.5% 99.0%
4979981 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.58 37.0 4.24e-01 72.9% 83.6%
5048590 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.58 37.0 4.29e-01 72.2% 84.5%
3627942 3755.4.1.1 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PI3K_P85_iSH2 0.58 37.0 3.48e-01 74.3% 53.7%
5081365 601.33.1.0 alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain 0.58 41.0 4.12e-01 81.2% 71.7%
4041347 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.58 36.0 4.16e-01 72.2% 82.7%
4991162 2484.1.1.302 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Cas12f1-like_TNB 0.56 43.0 3.72e-01 79.9% 60.9%
3256857 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 42.0 3.20e-01 99.3% 35.9%
3195080 109.4.1.368 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SHNi-TPR 0.55 42.0 3.21e-01 96.5% 35.6%
3877415 604.1.1.118 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › GOSR1_N 0.54 41.0 4.00e-01 99.3% 70.6%
3881211 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 44.0 3.32e-01 93.1% 43.8%
4170989 150.1.1.59 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Coat_F 0.51 39.0 3.91e-01 80.6% 86.0%
3638713 2003.1.2.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.51 45.0 3.06e-01 94.4% 75.8%
D6 medium residues 569-592_709-830
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00136.27 best DNA_pol_B 129.4 2.40e-37 83.6% 27.6%
PF00136.27 DNA_pol_B 26.9 3.00e-06 16.4% 5.3%
CATH (56)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2gv9B04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.94 87.0 7.66e-01 94.5% 100.0%
4fxdA05 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.84 63.0 7.03e-01 93.8% 95.7%
1q8iA04 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.79 75.0 6.48e-01 97.9% 74.2%
1d5aA03 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.74 57.0 5.50e-01 79.5% 89.0%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.71 48.0 5.05e-01 72.6% 76.2%
5wm1A02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.71 47.0 5.37e-01 87.0% 89.9%
3onqA02 3.30.70.2730 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 40.0 5.19e-01 72.6% 100.0%
1zpvA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.68 40.0 5.08e-01 84.2% 100.0%
2od4B01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 41.0 5.03e-01 71.2% 98.9%
2lqjA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.67 43.0 5.20e-01 84.9% 100.0%
5wpjA02 3.30.70.420 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain 0.66 47.0 5.36e-01 73.3% 100.0%
6eibD00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.66 55.0 5.45e-01 89.0% 98.7%
2py5A02 3.90.1600.10 Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain 0.66 60.0 5.55e-01 95.2% 78.2%
6hbzA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.66 55.0 5.38e-01 88.4% 85.5%
5xgbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.65 55.0 5.17e-01 91.1% 91.6%
3c19A01 3.30.70.1380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transcriptional regulatory protein pf0864 domain like 0.64 39.0 4.57e-01 80.8% 87.9%
4b6uA00 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.64 50.0 4.48e-01 93.8% 58.9%
1f3vA00 3.30.70.680 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TRADD, N-terminal domain 0.63 49.0 4.80e-01 84.2% 74.7%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.63 47.0 5.20e-01 80.1% 96.6%
3hvaA00 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.62 54.0 5.24e-01 92.5% 87.0%
1q8kA03 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.62 45.0 4.95e-01 87.0% 94.0%
1q8bA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 39.0 4.71e-01 72.6% 98.9%
1x7vA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 39.0 4.67e-01 72.6% 95.9%
2d1cA02 3.30.70.1570 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 43.0 4.92e-01 87.7% 95.5%
1q2lA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.61 53.0 4.54e-01 93.2% 95.2%
2ftrA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 41.0 4.77e-01 73.3% 98.1%
5yjlB01 3.30.460.30 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Glutamyl-tRNA reductase, N-terminal domain 0.60 46.0 4.44e-01 87.7% 70.8%
3eoqB02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.60 47.0 4.34e-01 81.5% 92.9%
5k8mA02 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 47.0 4.94e-01 81.5% 97.7%
5abxA00 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.60 48.0 4.52e-01 89.7% 71.1%
4xeaA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.60 47.0 4.25e-01 81.5% 90.6%
8c46A01 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 44.0 4.94e-01 81.5% 100.0%
4dn9B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 38.0 4.48e-01 74.0% 96.9%
5eufA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.59 46.0 4.22e-01 82.2% 90.5%
1q2lA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.59 50.0 4.29e-01 91.8% 82.3%
2g47A04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.59 49.0 4.13e-01 89.0% 87.5%
3amiA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.59 46.0 4.11e-01 81.5% 91.0%
2cg8B02 3.30.70.560 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK 0.58 49.0 5.19e-01 89.7% 99.2%
1lq9A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 42.0 4.72e-01 78.8% 98.2%
3mcsA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 50.0 4.35e-01 92.5% 86.1%
4hl9A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 37.0 4.41e-01 79.5% 98.9%
4nnzA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.57 47.0 4.27e-01 87.7% 99.0%
6ofsA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.57 46.0 4.00e-01 84.2% 94.5%
3e8oB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 38.0 4.37e-01 73.3% 98.0%
1jmtA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.57 38.0 4.44e-01 74.0% 100.0%
4uw2B03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.56 43.0 4.38e-01 88.4% 82.1%
2g47A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.56 48.0 4.14e-01 92.5% 94.8%
3go9A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.56 44.0 3.89e-01 84.2% 90.3%
3dpuB03 3.30.310.200 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › 0.56 39.0 4.43e-01 83.6% 97.2%
2ypyA00 3.30.70.390 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Epstein Barr virus nuclear antigen-1, DNA-binding domain 0.54 42.0 4.38e-01 80.1% 97.0%
2g47A03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.54 44.0 3.81e-01 87.0% 85.0%
2jpiA00 3.30.310.50 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Alpha-D-phosphohexomutase, C-terminal domain 0.53 35.0 4.09e-01 80.8% 100.0%
3popA02 3.40.462.20 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › 0.53 40.0 3.35e-01 90.4% 45.2%
4z9mB02 3.30.590.10 Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › Glutamine synthetase/guanido kinase, catalytic domain 0.53 42.0 3.82e-01 83.6% 94.4%
3aawA02 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.52 44.0 4.25e-01 91.8% 89.1%
1wvqA00 3.40.1520.10 Alpha Beta › 3-Layer(aba) Sandwich › hypothetical protein tt1634 › Ta1353-like 0.51 42.0 4.06e-01 89.0% 83.4%
ECOD (96)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4891101 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.92 65.0 6.06e-01 71.9% 95.3%
3484036 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.88 80.0 6.22e-01 93.8% 98.2%
3628202 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.87 80.0 4.99e-01 95.2% 37.1%
5019480 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.86 80.0 4.94e-01 96.6% 36.4%
5005286 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.86 78.0 5.91e-01 93.8% 87.5%
3089539 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.86 74.0 5.74e-01 89.7% 97.3%
None 0.85 80.0 4.98e-01 95.9% 38.9%
3480546 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.85 79.0 6.23e-01 95.2% 97.4%
3558196 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.85 79.0 6.12e-01 95.9% 86.7%
None 0.85 78.0 4.86e-01 93.8% 38.0%
4022366 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.85 78.0 4.89e-01 94.5% 38.6%
4231530 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.85 80.0 6.94e-01 97.3% 99.0%
3684974 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.84 77.0 4.78e-01 94.5% 38.9%
3705562 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.84 78.0 4.82e-01 95.2% 41.4%
3615419 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.84 79.0 5.80e-01 97.3% 87.3%
3784383 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.84 77.0 5.46e-01 94.5% 70.3%
3801150 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.83 78.0 5.94e-01 96.6% 82.4%
3597965 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.81 74.0 6.03e-01 94.5% 98.4%
4029141 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.81 77.0 6.14e-01 98.6% 93.1%
3993981 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.80 73.0 6.12e-01 93.8% 98.2%
3349591 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.79 72.0 5.56e-01 94.5% 78.6%
3466667 2484.1.1.161 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.79 74.0 4.64e-01 97.3% 34.3%
4972474 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.79 73.0 4.53e-01 95.9% 34.1%
4276636 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.78 74.0 5.43e-01 97.3% 77.0%
5017083 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.78 71.0 5.58e-01 93.8% 85.6%
4958554 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.76 72.0 5.93e-01 97.3% 97.0%
4282509 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.75 71.0 4.56e-01 97.9% 31.5%
4942685 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.75 69.0 4.57e-01 94.5% 45.2%
3705695 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.74 65.0 5.39e-01 93.2% 85.7%
4629010 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.74 63.0 5.32e-01 89.0% 83.6%
4956224 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.73 68.0 5.57e-01 95.2% 91.5%
4144335 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.73 63.0 5.06e-01 89.7% 84.2%
4100823 4970.1.1.1 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › DNA_pol_B 0.73 66.0 5.41e-01 95.2% 84.0%
3797416 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.72 63.0 5.05e-01 91.8% 84.1%
3206807 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.72 63.0 5.00e-01 91.1% 80.7%
3464384 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.72 62.0 5.06e-01 90.4% 80.8%
3189629 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.72 63.0 4.29e-01 92.5% 49.7%
4022145 2484.1.1.153 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF1744 0.72 62.0 3.98e-01 90.4% 33.2%
3578106 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.72 65.0 5.15e-01 95.2% 83.3%
3877126 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.72 60.0 3.80e-01 88.4% 32.1%
4182409 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.72 61.0 5.97e-01 90.4% 88.1%
3508610 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.71 59.0 4.83e-01 87.0% 82.0%
3831499 304.48.1.63 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B, DUF1744 0.71 62.0 3.89e-01 92.5% 29.9%
3266689 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.71 60.0 4.83e-01 87.7% 83.5%
3741560 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.71 65.0 5.19e-01 96.6% 83.3%
3591115 304.163.1.0 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain 0.71 48.0 5.65e-01 79.5% 99.0%
4419306 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.71 65.0 5.62e-01 95.2% 93.3%
3924217 304.48.1.24 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DUF1744 0.71 58.0 4.72e-01 86.3% 80.4%
3588477 304.31.1.1 a+b two layers › Alpha-beta plaits › HMG-CoA reductase › NAD-binding domain of HMG-CoA reductase › HMG-CoA_red 0.70 50.0 5.64e-01 73.3% 100.0%
5040510 304.48.1.3 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B 0.69 64.0 5.19e-01 95.9% 94.3%
5018772 304.55.2.0 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.68 42.0 4.99e-01 82.2% 92.6%
5027042 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.67 40.0 4.86e-01 81.5% 96.6%
4033498 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.67 47.0 4.41e-01 71.9% 93.1%
4264107 304.48.1.17 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › DNA_pol_B_2 0.66 63.0 4.80e-01 99.3% 79.3%
4022835 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.66 49.0 2.92e-01 76.7% 36.0%
3615648 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.66 45.0 5.28e-01 73.3% 98.1%
4336502 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.64 47.0 4.36e-01 74.7% 93.0%
4956622 304.25.1.0 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain 0.64 48.0 5.33e-01 82.2% 97.4%
3765409 304.47.1.1 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA 0.64 45.0 4.97e-01 74.0% 91.3%
3972699 304.28.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran 0.63 46.0 5.21e-01 84.2% 100.0%
4219210 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.63 46.0 5.19e-01 86.3% 100.0%
1146572 304.152.1.1 a+b two layers › Alpha-beta plaits › E4-ORF3 › E4-ORF3 › Adeno_E4_ORF3 0.63 45.0 4.94e-01 72.6% 94.8%
1524343 304.48.1.31 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.62 51.0 4.79e-01 88.4% 79.8%
3713509 304.48.1.10 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › IMS 0.61 52.0 4.47e-01 91.1% 88.3%
3955398 304.51.1.0 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related 0.61 43.0 4.87e-01 72.6% 96.4%
3413435 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.60 48.0 4.14e-01 84.9% 85.1%
3498405 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.60 48.0 4.07e-01 84.2% 83.7%
3445307 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.60 48.0 4.11e-01 85.6% 81.7%
1183435 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.60 47.0 4.30e-01 81.5% 91.0%
4939612 304.51.1.0 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related 0.60 44.0 4.86e-01 76.0% 99.1%
3787184 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.60 49.0 4.11e-01 86.3% 81.6%
3601349 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.60 51.0 3.09e-01 89.7% 40.4%
3971024 309.1.1.9 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PQQ_syn_pqqF_N_2 0.60 51.0 4.68e-01 91.8% 85.8%
3301512 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.60 49.0 4.12e-01 86.3% 82.9%
3987564 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.60 46.0 4.29e-01 80.8% 89.7%
1513114 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.60 47.0 4.28e-01 81.5% 92.1%
4990439 304.116.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in release factor › Ferredoxin-like domain in release factor 0.60 40.0 4.68e-01 84.2% 98.0%
3685056 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.60 48.0 4.01e-01 84.9% 80.8%
4033409 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.60 46.0 4.29e-01 81.5% 94.1%
1716092 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.60 46.0 4.15e-01 80.8% 85.6%
2388574 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.59 47.0 4.06e-01 84.9% 88.3%
5511 309.1.1.6 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C,Peptidase_M16_M 0.59 50.0 4.24e-01 91.8% 79.2%
3727958 304.28.1.16 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › AtuA 0.59 42.0 4.53e-01 73.3% 93.3%
3718659 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.58 49.0 3.23e-01 89.7% 54.8%
3497745 309.1.1.11 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PqqF-like_C_4 0.58 48.0 3.93e-01 89.7% 92.5%
1841235 309.1.1.9 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › PQQ_syn_pqqF_N_2 0.58 49.0 4.30e-01 91.8% 76.7%
3741142 309.1.1.17 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16, Peptidase_M16_C, Peptidase_M16_M, PqqF-like_C_4 0.57 50.0 3.07e-01 96.6% 37.3%
3371431 304.116.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in release factor › Ferredoxin-like domain in release factor › PCRF 0.57 40.0 4.49e-01 71.9% 96.4%
5063875 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.57 45.0 4.13e-01 84.2% 93.3%
3164823 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.57 45.0 3.89e-01 84.2% 88.3%
3652924 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.56 45.0 3.82e-01 84.2% 81.7%
3609636 309.1.1.0 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase 0.56 49.0 3.97e-01 97.3% 89.0%
4089557 309.1.1.16 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16, Peptidase_M16_C, M16C_assoc, PreP_C 0.56 47.0 2.91e-01 93.8% 40.4%
5063044 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.55 43.0 4.12e-01 82.9% 94.9%
3952827 309.1.1.4 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_C 0.55 46.0 4.12e-01 91.1% 94.7%
3659455 331.4.1.2 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › NAF 0.51 36.0 3.78e-01 71.2% 93.1%