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OTU-like_cysteine_protease

Euk-Vir

Emiliania_huxleyi_virus_86

OTU-like_cysteine_protease__YP_002296183__Emiliania_huxleyi_virus_86__181082

Identity

Accession:
YP_002296183 ↗
Protein ID:
OTU-like_cysteine_protease
Kingdom:
euk

Quality

83.2 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Algavirales› Phycodnaviridae› Coccolithovirus› Emiliania_huxleyi_virus_86

TaxID: 181082

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-45_103-149
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4bouA00 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.72 67.0 5.69e-01 100.0% 99.3%
3by4A00 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.71 63.0 5.01e-01 93.5% 78.5%
5jzeA00 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.66 63.0 5.09e-01 100.0% 87.4%
1js3A03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.60 34.0 3.43e-01 93.5% 51.5%
4kc5B01 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.59 52.0 3.32e-01 100.0% 85.7%
7x0fA01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.56 42.0 3.66e-01 81.5% 78.4%
4hvmB01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.56 42.0 3.41e-01 82.6% 61.2%
5by7A02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.54 40.0 3.47e-01 79.3% 100.0%
2w1jA00 2.40.260.10 Mainly Beta › Beta Barrel › Sortase; Chain: A; › Sortase 0.52 47.0 3.69e-01 100.0% 96.4%
6n8eA02 3.30.559.30 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Nonribosomal peptide synthetase, condensation domain 0.52 39.0 2.95e-01 82.6% 71.2%
3akjA01 3.30.200.120 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › 0.52 37.0 3.98e-01 95.7% 93.2%
5k9aA00 2.40.260.10 Mainly Beta › Beta Barrel › Sortase; Chain: A; › Sortase 0.52 46.0 3.53e-01 100.0% 59.1%
7c1hB01 3.30.559.10 Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain 0.51 39.0 3.26e-01 82.6% 66.3%
3uc4A01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 39.0 4.09e-01 100.0% 91.8%
1s9iB01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.51 40.0 4.00e-01 98.9% 84.9%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3741412 219.1.1.15 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › OTU 0.79 71.0 5.84e-01 94.6% 94.8%
3732360 219.1.1.15 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › OTU 0.77 68.0 5.30e-01 93.5% 93.9%
3935022 219.1.1.15 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › OTU 0.71 66.0 5.43e-01 100.0% 91.0%
5027191 3012.1.1.0 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.57 33.0 3.70e-01 90.2% 72.9%
4934415 3012.1.1.0 ↗ a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain 0.55 32.0 3.61e-01 90.2% 80.0%
4942376 305.2.1.1 ↗ a+b two layers › DCoH-like › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH) › Pterin_4a 0.54 37.0 3.56e-01 91.3% 60.9%
3371305 323.1.1.7 ↗ a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Transferase 0.53 40.0 3.26e-01 80.4% 86.1%
3244878 864.1.1.5 ↗ a+b two layers › DLC › DLC › DLC › DUF684 0.52 40.0 4.17e-01 98.9% 90.6%
3585186 391.1.1.0 ↗ few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module 0.52 24.0 3.08e-01 98.9% 100.0%
5014115 3111.1.1.0 ↗ beta barrels › STT3/PglB/AglB beta-barrel domain › STT3/PglB/AglB beta-barrel domain › STT3/PglB/AglB beta-barrel domain 0.52 37.0 4.03e-01 77.2% 97.3%
3519410 391.1.1.0 ↗ few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module 0.51 24.0 3.07e-01 96.7% 89.7%
3290745 3016.1.1.0 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.51 34.0 3.37e-01 91.3% 65.3%
None — 0.51 40.0 3.00e-01 85.9% 44.1%
D2 medium residues 46-102
PDB
Domain cluster: representative
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7pl7A01 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.87 81.0 5.74e-01 100.0% 42.1%
4bopB00 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.84 78.0 5.61e-01 100.0% 40.0%
3tmpA01 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.84 78.0 5.58e-01 100.0% 40.7%
3by4A00 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.75 67.0 4.73e-01 100.0% 35.5%
1q1vA00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.64 40.0 3.78e-01 98.2% 51.4%
3pvlA03 1.20.80.10 Mainly Alpha › Up-down Bundle › Acyl-CoA Binding Protein › 0.63 49.0 3.93e-01 87.7% 91.5%
1irxA04 1.10.10.770 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.61 42.0 3.37e-01 71.9% 83.3%
2xzmV01 1.10.60.20 Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 0.60 35.0 3.49e-01 91.2% 54.1%
4ol8B03 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.56 44.0 3.93e-01 93.0% 100.0%
1u6mA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.55 47.0 3.31e-01 98.2% 59.8%
3f2eA00 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 38.0 3.49e-01 75.4% 88.0%
1hwyA03 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 2.91e-01 96.5% 86.8%
3bz6A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 39.0 3.42e-01 86.0% 50.0%
4didB01 1.20.58.450 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Cell division control protein 42 homolog 0.54 45.0 3.62e-01 94.7% 53.5%
2mh3A00 4.10.280.10 Few Secondary Structures › Irregular › MYOD Basic-Helix-Loop-Helix Domain, subunit B › Helix-loop-helix DNA-binding domain 0.52 38.0 3.64e-01 91.2% 67.1%
3mg2B01 1.10.2090.10 Mainly Alpha › Orthogonal Bundle › orange carotenoid protein, domain 2 › Orange carotenoid-binding protein, N-terminal domain 0.51 43.0 3.23e-01 96.5% 89.8%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4028903 219.1.1.15 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › OTU 0.82 76.0 5.35e-01 100.0% 38.7%
3582922 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.76 55.0 4.81e-01 100.0% 53.8%
3828000 145.1.1.0 ↗ alpha arrays › F-box domain › F-box domain › F-box domain 0.65 35.0 3.88e-01 98.2% 64.4%
4050022 101.35.1.4 ↗ alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH3 0.62 39.0 3.98e-01 93.0% 65.5%
4371976 2004.1.1.226 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ADDB_N 0.62 54.0 3.03e-01 100.0% 12.5%
3937078 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.62 38.0 3.38e-01 100.0% 42.4%
3604422 101.1.4.0 ↗ alpha arrays › HTH › HTH › tetra-helical, lambda repressor-like 0.61 50.0 4.81e-01 100.0% 90.0%
3272426 314.1.1.9 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › tRNA-synt_His 0.61 50.0 3.10e-01 93.0% 15.2%
4142393 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.59 41.0 2.93e-01 73.7% 99.5%
None — 0.56 45.0 2.88e-01 93.0% 16.8%
3239257 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.55 37.0 3.67e-01 89.5% 66.7%
4516913 2485.1.1.10 ↗ a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › DSBA 0.51 40.0 2.90e-01 93.0% 32.6%
144750 150.3.1.3 ↗ alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IL6 0.50 43.0 3.03e-01 96.5% 58.2%