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OY725315.1__CAJ1224355.1__AUSP0087_00007__00007

Bact-Vir

OY725315.1__CAJ1224355.1__AUSP0087_00007__00007

Identity

Accession:
OY725315 ↗
Kingdom:
phage

Quality

64.5 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 1135-1274
PDB
Domain cluster: representative
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3onjA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.77 47.0 5.56e-01 100.0% 87.6%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.77 43.0 4.70e-01 100.0% 64.7%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.77 42.0 4.49e-01 100.0% 61.2%
3agtA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.76 41.0 4.26e-01 98.6% 55.6%
3iqcA00 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.75 39.0 4.21e-01 97.1% 58.8%
4aifA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.75 38.0 3.77e-01 100.0% 47.9%
1sziA02 1.20.120.340 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS 0.73 43.0 4.38e-01 100.0% 59.9%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 43.0 3.54e-01 90.7% 35.3%
2xq9A02 1.20.58.390 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain 0.72 33.0 3.59e-01 90.0% 49.6%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.72 43.0 4.52e-01 100.0% 65.3%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 43.0 5.13e-01 100.0% 92.4%
1wcrA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.70 43.0 4.92e-01 100.0% 83.5%
1elrA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 28.0 2.93e-01 100.0% 38.3%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.69 42.0 4.96e-01 100.0% 86.7%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 43.0 4.81e-01 100.0% 83.0%
4xpwA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.67 40.0 4.15e-01 100.0% 63.4%
1i5nB00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.65 27.0 2.93e-01 87.1% 41.1%
3kbtA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 41.0 3.25e-01 100.0% 31.3%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 40.0 4.41e-01 98.6% 80.0%
4u04B01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.62 26.0 3.19e-01 100.0% 56.8%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 38.0 4.40e-01 100.0% 84.3%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.62 40.0 4.46e-01 97.9% 82.7%
2kmfA01 1.20.58.810 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 0.62 31.0 3.62e-01 96.4% 65.7%
5nl6A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 38.0 4.27e-01 100.0% 79.6%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.61 41.0 3.86e-01 100.0% 56.2%
1e2aA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.61 38.0 4.36e-01 100.0% 84.3%
4q5nA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 34.0 3.73e-01 95.7% 67.0%
3nvoB02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.59 39.0 4.25e-01 100.0% 80.2%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.59 48.0 4.38e-01 87.9% 87.4%
2oexA02 1.20.140.50 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains 0.58 39.0 3.47e-01 90.7% 48.7%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.57 36.0 3.88e-01 94.3% 73.6%
2juaA00 1.20.1480.30 Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Designed four-helix bundle protein 0.57 40.0 4.61e-01 77.1% 100.0%
3k53A02 1.10.287.1770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.56 34.0 3.91e-01 75.0% 84.7%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 51.0 4.61e-01 100.0% 82.1%
3qhbA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 45.0 4.16e-01 85.7% 71.5%
7zxkC01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 42.0 4.17e-01 80.0% 76.7%
2i2xB01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.55 33.0 3.84e-01 100.0% 83.0%
1jogA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.55 41.0 4.25e-01 96.4% 82.2%
1qmgA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.52 41.0 3.22e-01 83.6% 62.5%
8ex5A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.51 43.0 3.89e-01 89.3% 95.8%
1fntc01 1.20.120.180 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain 0.51 41.0 3.69e-01 100.0% 62.8%
3owaA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 42.0 3.97e-01 89.3% 94.7%
4xvxA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.51 41.0 4.13e-01 87.9% 95.2%
2nwbA02 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.50 41.0 3.45e-01 87.1% 80.6%
1yq3C02 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.50 33.0 3.68e-01 93.6% 85.2%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3995355 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.79 45.0 4.68e-01 100.0% 60.0%
3239453 601.1.2.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin 0.79 44.0 4.52e-01 99.3% 57.0%
3272619 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.79 46.0 5.00e-01 100.0% 68.3%
3252760 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.75 47.0 5.14e-01 100.0% 76.3%
4012021 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.75 31.0 3.41e-01 97.9% 45.8%
3253929 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.74 42.0 4.52e-01 100.0% 64.2%
3253937 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.74 43.0 4.62e-01 100.0% 66.7%
3249525 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.72 46.0 4.61e-01 100.0% 62.1%
5012487 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.72 40.0 4.04e-01 100.0% 53.1%
3253930 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.71 43.0 4.57e-01 100.0% 68.3%
4338603 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.71 41.0 4.30e-01 100.0% 62.4%
3599723 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.71 46.0 4.69e-01 100.0% 66.7%
3253932 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.70 42.0 4.44e-01 100.0% 65.6%
4004414 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.68 41.0 4.53e-01 99.3% 74.5%
5014407 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.66 44.0 4.13e-01 100.0% 55.3%
3583810 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.66 42.0 4.48e-01 100.0% 72.0%
3624840 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.66 38.0 3.01e-01 95.7% 28.4%
4988621 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.65 38.0 3.03e-01 90.0% 29.3%
3789281 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.65 46.0 3.90e-01 100.0% 44.8%
4020948 611.9.1.0 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain 0.64 31.0 3.37e-01 85.7% 53.0%
3467355 109.4.1.359 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo70_C 0.64 41.0 3.45e-01 100.0% 38.7%
3923983 174.1.1.44 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF30976 0.64 42.0 3.78e-01 100.0% 47.7%
5057941 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.63 41.0 3.84e-01 98.6% 52.9%
4024992 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.63 44.0 4.43e-01 100.0% 70.3%
3975613 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.62 36.0 3.19e-01 95.7% 39.0%
4099744 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.61 32.0 3.74e-01 95.7% 69.0%
3303755 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.59 36.0 3.72e-01 99.3% 63.1%
3654966 603.1.1.6 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 0.59 36.0 3.69e-01 87.9% 62.1%
3473142 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.58 41.0 4.19e-01 100.0% 73.6%
3185438 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.58 53.0 4.69e-01 100.0% 85.0%
3969040 4121.1.1.1 a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA 0.58 42.0 3.44e-01 100.0% 41.6%
3644738 192.29.1.48 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Chloroplast_duf 0.58 35.0 3.05e-01 90.7% 39.0%
3610367 5054.1.1.0 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.57 47.0 3.53e-01 87.9% 52.5%
3495474 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.57 46.0 4.08e-01 84.3% 98.5%
4944902 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.57 46.0 4.12e-01 85.7% 97.9%
3222435 606.1.1.1 alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop 0.56 51.0 4.88e-01 100.0% 95.8%
5064484 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 46.0 4.10e-01 87.9% 97.5%
3600606 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.54 42.0 3.95e-01 100.0% 66.3%
5045448 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 42.0 3.72e-01 82.9% 90.7%
3972092 603.6.1.9 alpha bundles › STAT-like › MukF C-terminal domain-like › MukF C-terminal domain-like › PF28010 0.53 40.0 3.61e-01 100.0% 57.9%
3331616 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 43.0 3.65e-01 88.6% 91.7%
4978799 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 42.0 3.74e-01 85.7% 94.1%
3592036 3291.1.1.16 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Flagellar_rod 0.52 47.0 4.09e-01 100.0% 65.7%
4307928 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 42.0 3.66e-01 88.6% 86.8%
D2 medium residues 58-128
PDB
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2n3eA01 1.10.274.70 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain 0.74 48.0 4.08e-01 71.8% 40.9%
4qicC01 1.20.140.160 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › PhyR, sigma-like (SL) domain 0.74 58.0 4.73e-01 83.1% 53.6%
2i5uA00 1.10.10.630 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DnaD domain-like 0.72 57.0 5.56e-01 85.9% 80.5%
4nqwA01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.72 57.0 5.35e-01 84.5% 77.4%
1dcnA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.67 50.0 5.05e-01 80.3% 80.6%
3fvvA02 1.20.1440.100 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › SG protein - dephosphorylation function 0.65 47.0 4.65e-01 77.5% 73.3%
1lp1A00 1.20.5.420 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C 0.64 45.0 4.93e-01 78.9% 96.4%
3t0yA01 1.10.1740.10 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif 0.63 54.0 5.66e-01 97.2% 100.0%
3o3mB01 1.20.1270.370 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.62 53.0 4.69e-01 94.4% 67.0%
3if8B02 1.20.58.730 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 53.0 4.77e-01 100.0% 81.0%
4i5lB01 1.10.238.230 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › 0.58 44.0 3.95e-01 81.7% 67.0%
3rmiA00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.58 41.0 3.58e-01 73.2% 61.9%
2g8lB01 1.10.8.380 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein PF01937, DUF89, domain 1 0.58 48.0 4.89e-01 93.0% 100.0%
7tvyA01 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.58 43.0 3.73e-01 81.7% 50.9%
3nbiA01 1.10.8.1020 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › RecQ-mediated genome instability protein 1, N-terminal domain 0.55 41.0 4.47e-01 83.1% 100.0%
2nsaA00 1.10.3120.10 Mainly Alpha › Orthogonal Bundle › Trigger factor, domain 2 › Trigger factor, C-terminal domain 0.54 46.0 3.48e-01 93.0% 53.9%
4j8sA00 1.25.40.840 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › CCR4-NOT transcription complex subunit 1 TTP binding domain 0.51 44.0 3.22e-01 94.4% 36.7%
3ez2A01 1.10.1660.30 Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › 0.50 35.0 3.59e-01 74.6% 84.3%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3813017 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.79 61.0 5.45e-01 80.3% 82.1%
3029394 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.77 55.0 6.16e-01 76.1% 98.1%
3114 4230.1.1.3 alpha arrays › DnaD domain › DnaD domain › DnaD domain › DnaB_2 0.72 57.0 5.64e-01 85.9% 83.8%
5046657 4953.1.1.2 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ADSL_C 0.72 51.0 5.21e-01 76.1% 75.7%
3995291 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.72 56.0 5.82e-01 87.3% 92.3%
3967936 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.71 56.0 5.57e-01 84.5% 86.7%
3967283 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.71 57.0 5.16e-01 85.9% 69.5%
3974456 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.71 56.0 5.55e-01 84.5% 89.3%
3288147 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.71 57.0 5.03e-01 85.9% 61.0%
4196260 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.69 54.0 4.85e-01 84.5% 67.0%
5080578 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.69 46.0 5.04e-01 73.2% 89.1%
3960310 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.69 56.0 5.64e-01 85.9% 88.6%
4185350 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.68 54.0 5.22e-01 85.9% 81.2%
5001478 4953.1.1.2 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ADSL_C 0.67 58.0 5.60e-01 94.4% 82.5%
1194681 4953.1.1.2 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ADSL_C 0.65 55.0 4.88e-01 94.4% 64.7%
4952935 4009.1.1.0 alpha bundles › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins › alpha-helical domain in AF1104-like proteins 0.63 47.0 4.82e-01 80.3% 96.9%
3786780 3431.1.1.1 alpha bundles › Helical domain in autophagy protein 5 › Helical domain in autophagy protein 5 › Helical domain in autophagy protein 5 › ATG5_HBR 0.63 47.0 5.03e-01 78.9% 100.0%
3783718 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.62 47.0 4.79e-01 81.7% 82.9%
4498700 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.60 54.0 4.78e-01 98.6% 83.0%
5019279 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.58 44.0 3.04e-01 84.5% 79.6%
3968817 3831.1.1.1 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.57 43.0 4.16e-01 85.9% 95.3%
D3 medium residues 350-448
PDB
D4 medium residues 569-649
PDB
Domain cluster: representative
CATH (55)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.87 60.0 4.06e-01 74.1% 22.3%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.84 60.0 5.08e-01 72.8% 48.4%
3lnnB03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.83 56.0 6.21e-01 72.8% 85.1%
4iggA01 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.82 58.0 6.40e-01 72.8% 88.1%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.82 58.0 5.61e-01 72.8% 79.5%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.80 57.0 3.99e-01 74.1% 26.4%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 54.0 6.22e-01 71.6% 94.9%
6grjB01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.80 57.0 3.73e-01 74.1% 19.9%
4mycA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.79 55.0 3.56e-01 71.6% 24.4%
1kmiZ02 1.10.287.500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.78 55.0 4.59e-01 72.8% 44.8%
1rq0A01 6.10.140.160 Special › Helix non-globular › Helix Hairpins › 0.77 50.0 5.03e-01 74.1% 65.1%
4jvsA01 1.20.120.1700 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.77 53.0 4.52e-01 71.6% 50.0%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.76 61.0 6.29e-01 85.2% 90.8%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 53.0 3.86e-01 72.8% 28.1%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 53.0 3.70e-01 74.1% 34.4%
1tjlA00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.75 60.0 4.95e-01 87.7% 64.1%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.75 57.0 3.95e-01 82.7% 44.4%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.74 53.0 3.78e-01 75.3% 51.1%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.74 52.0 4.76e-01 74.1% 60.7%
4q4hA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.74 51.0 3.41e-01 72.8% 18.9%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.73 51.0 3.80e-01 74.1% 52.1%
6v9zA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.73 50.0 3.31e-01 71.6% 18.2%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.73 52.0 5.65e-01 74.1% 93.9%
1st6A04 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.73 55.0 4.89e-01 81.5% 58.1%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.72 55.0 4.89e-01 82.7% 59.8%
4mtxD00 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.70 50.0 4.74e-01 74.1% 65.3%
1i6zA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.70 56.0 4.73e-01 86.4% 61.5%
4fzsA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 49.0 3.66e-01 74.1% 29.2%
1h6gA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.69 55.0 4.83e-01 85.2% 58.8%
3qa8A04 1.20.1270.250 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.69 48.0 3.45e-01 72.8% 41.2%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.69 58.0 5.37e-01 90.1% 74.3%
3i9wA00 1.20.58.920 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 48.0 3.39e-01 74.1% 22.6%
3vkgA12 1.10.287.2610 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 48.0 3.57e-01 74.1% 74.4%
4qgpB00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.68 55.0 5.00e-01 92.6% 65.4%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 56.0 5.36e-01 90.1% 83.3%
2xubA05 6.10.140.1450 Special › Helix non-globular › Helix Hairpins › 0.68 48.0 4.60e-01 74.1% 78.1%
4hwdD00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.68 52.0 5.10e-01 90.1% 74.4%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 51.0 4.48e-01 84.0% 53.7%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.66 51.0 5.03e-01 90.1% 76.1%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 46.0 4.29e-01 72.8% 57.3%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 54.0 5.20e-01 90.1% 87.0%
2b7mA00 1.20.1280.170 Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 0.66 49.0 2.99e-01 90.1% 12.5%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.66 47.0 4.70e-01 84.0% 72.9%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 50.0 4.49e-01 81.5% 77.5%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 51.0 4.18e-01 86.4% 82.7%
4hkaA01 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.65 58.0 3.92e-01 98.8% 46.6%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.64 45.0 4.45e-01 75.3% 81.1%
4uvmA00 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.64 53.0 3.30e-01 93.8% 15.2%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.64 50.0 4.57e-01 85.2% 66.1%
3r6nA02 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 51.0 4.08e-01 85.2% 45.8%
3gnlB02 1.10.287.1890 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 49.0 5.26e-01 93.8% 100.0%
1cxzB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.62 50.0 4.97e-01 90.1% 100.0%
2p7vA00 1.20.120.1370 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 0.62 50.0 4.13e-01 90.1% 66.9%
3wfwA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.57 48.0 4.14e-01 100.0% 57.2%
8ipqB01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.55 48.0 3.33e-01 98.8% 93.4%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3862609 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.92 65.0 5.37e-01 72.8% 45.4%
3612941 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.86 61.0 4.94e-01 72.8% 67.1%
4189855 1203.1.2.11 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › PPPI_inhib 0.86 64.0 4.74e-01 76.5% 48.3%
4033697 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.86 60.0 5.46e-01 72.8% 56.2%
3258488 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.86 57.0 5.24e-01 72.8% 55.0%
5041482 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.85 61.0 5.76e-01 74.1% 63.2%
4397490 164.1.1.15 alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › PPPI_inhib 0.85 63.0 4.77e-01 76.5% 51.2%
4470384 1203.1.2.11 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › PPPI_inhib 0.85 62.0 4.67e-01 76.5% 48.3%
3763261 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.83 59.0 4.20e-01 74.1% 88.2%
3235287 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.82 59.0 3.92e-01 74.1% 21.8%
3416429 2004.1.1.442 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21 0.82 57.0 3.58e-01 72.8% 21.8%
3662731 1075.4.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold 0.82 52.0 3.66e-01 72.8% 22.6%
3671258 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.81 58.0 4.87e-01 74.1% 46.9%
3932987 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.81 61.0 4.15e-01 79.0% 41.9%
3775580 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.80 57.0 5.90e-01 72.8% 78.7%
4031582 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.80 57.0 4.19e-01 74.1% 34.0%
3657504 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.80 57.0 4.75e-01 74.1% 75.6%
3859640 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.80 57.0 4.26e-01 74.1% 31.6%
4942654 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.80 57.0 4.46e-01 74.1% 38.1%
3849547 4992.1.1.25 extended segments › RelB-like › RelB-like › RelB-like › SHCBP_N 0.80 56.0 5.31e-01 74.1% 62.1%
3282558 375.1.9.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase 0.79 56.0 4.13e-01 72.8% 30.3%
3229095 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.79 57.0 5.25e-01 74.1% 61.0%
3205388 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.79 56.0 3.93e-01 72.8% 37.0%
3539308 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.79 56.0 3.91e-01 74.1% 26.8%
3538954 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.79 56.0 3.77e-01 74.1% 21.8%
4136919 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.79 56.0 4.23e-01 74.1% 33.0%
3880637 3755.3.1.465 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF21A 0.78 55.0 4.57e-01 74.1% 51.4%
3583471 601.2.1.1 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › 7tm_1 0.78 55.0 4.28e-01 74.1% 35.3%
3695102 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.78 63.0 3.89e-01 86.4% 22.1%
3634896 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.77 54.0 4.82e-01 74.1% 55.7%
3220862 174.1.1.55 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF26941 0.77 65.0 5.53e-01 90.1% 93.6%
3505878 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.77 55.0 3.66e-01 74.1% 20.7%
3906366 5057.1.1.1 alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neur_chan_memb 0.76 54.0 4.26e-01 74.1% 38.1%
4451131 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.76 54.0 4.42e-01 74.1% 84.8%
3699463 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.76 54.0 3.88e-01 74.1% 28.4%
4257134 192.5.1.35 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › Hobbit 0.76 54.0 4.99e-01 74.1% 61.0%
3702706 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.75 54.0 5.43e-01 74.1% 76.2%
3226751 604.3.1.13 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF19 0.75 54.0 4.38e-01 85.2% 40.7%
3607008 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.75 54.0 5.09e-01 74.1% 64.2%
4489485 11.1.1.2 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › fn3 0.75 53.0 3.96e-01 72.8% 35.9%
4286404 3755.1.1.14 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › T3SSipB 0.75 52.0 4.03e-01 72.8% 33.3%
3968965 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.74 53.0 5.18e-01 88.9% 67.8%
5082774 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.73 52.0 4.20e-01 74.1% 40.7%
4962781 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.73 51.0 5.28e-01 72.8% 77.3%
3903553 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.73 53.0 4.73e-01 79.0% 53.9%
5077926 101.1.2.14 alpha arrays › HTH › HTH › winged helix domain › HTH_5 0.73 57.0 4.75e-01 82.7% 49.6%
5072280 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.73 51.0 3.77e-01 74.1% 28.8%
4646268 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.73 51.0 5.39e-01 72.8% 94.3%
3813837 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.73 51.0 5.30e-01 74.1% 90.7%
3783036 4177.1.1.2 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR 0.73 56.0 3.86e-01 81.5% 75.3%
4673482 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.72 54.0 4.07e-01 79.0% 68.9%
3488340 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.72 57.0 5.08e-01 85.2% 60.9%
4446057 192.8.1.345 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › PF30463 0.72 50.0 3.70e-01 72.8% 31.0%
4249486 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.72 51.0 3.63e-01 74.1% 25.4%
3908483 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.71 61.0 4.98e-01 92.6% 86.2%
3886230 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.71 56.0 4.23e-01 86.4% 65.8%
3933806 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.70 49.0 4.25e-01 74.1% 46.2%
3180975 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.70 50.0 3.77e-01 74.1% 32.1%
4298288 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.70 51.0 4.25e-01 80.2% 45.9%
3781013 3291.1.1.170 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › WWC1 0.69 49.0 4.16e-01 74.1% 46.7%
3743077 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 58.0 4.99e-01 90.1% 60.0%
2555592 5069.1.1.3 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_I 0.69 48.0 4.80e-01 74.1% 71.8%
3596042 4163.1.1.0 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like 0.68 55.0 4.62e-01 86.4% 60.0%
3421052 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.68 48.0 3.48e-01 74.1% 28.1%
4986986 3633.1.1.0 alpha duplicates or obligate multimers › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor › Haptoglobin-hemoglobin receptor 0.68 48.0 3.62e-01 74.1% 29.8%
3277563 603.2.1.2 alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil 0.68 56.0 4.78e-01 90.1% 63.1%
3177410 109.4.1.335 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SEN1_N 0.68 58.0 3.33e-01 100.0% 13.7%
3503849 4177.1.1.10 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › GMIP-like_FCH 0.68 56.0 3.82e-01 91.4% 42.0%
4305317 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.68 47.0 2.78e-01 74.1% 11.5%
3980428 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.68 48.0 4.94e-01 74.1% 100.0%
None 0.67 47.0 3.48e-01 74.1% 30.0%
3703064 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.67 56.0 4.64e-01 90.1% 57.1%
3282638 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.65 56.0 4.73e-01 93.8% 91.1%
3713898 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.65 50.0 3.86e-01 86.4% 52.0%
3709562 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 52.0 4.27e-01 90.1% 90.7%
5014085 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.63 54.0 3.65e-01 95.1% 75.3%
4000502 192.8.1.305 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › VPS18_RING_C 0.63 43.0 3.96e-01 71.6% 59.1%
3564754 604.1.1.96 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Bap31 0.62 51.0 4.30e-01 90.1% 81.5%
4888150 1075.4.1.9 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran+ABC_membrane 0.62 52.0 3.46e-01 93.8% 66.4%
4085341 622.1.1.1 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C 0.62 52.0 4.96e-01 95.1% 78.9%
3746208 601.18.1.6 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Got1 0.60 51.0 4.21e-01 97.5% 93.5%
D5 medium residues 1275-1373
PDB
Domain cluster: representative
CATH (13)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.73 47.0 4.91e-01 99.0% 71.4%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.72 50.0 5.54e-01 71.7% 100.0%
4fwvA02 1.20.120.1680 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.69 51.0 4.67e-01 78.8% 88.1%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.68 47.0 5.29e-01 72.7% 94.6%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 48.0 4.90e-01 100.0% 75.0%
1wp1B01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.67 48.0 3.23e-01 73.7% 48.8%
4ys0A02 1.10.3060.10 Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA 0.66 47.0 3.87e-01 73.7% 42.4%
3tbiB02 6.10.140.1670 Special › Helix non-globular › Helix Hairpins › 0.66 48.0 4.87e-01 77.8% 99.0%
2oznB01 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.64 39.0 4.31e-01 97.0% 76.2%
2h7oA02 1.20.58.1230 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Rac1-binding domain, C-terminal subdomain 0.63 45.0 3.92e-01 73.7% 62.6%
4dhxB00 1.10.246.140 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › ENY2/SUS1 0.62 46.0 4.76e-01 76.8% 84.6%
3ckdA02 1.20.58.360 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Shigella T3SS effector IpaH defines 0.55 49.0 4.54e-01 99.0% 79.8%
6lumG01 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.51 42.0 4.04e-01 97.0% 77.7%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4983021 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.72 55.0 4.80e-01 80.8% 78.0%
3412019 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.70 48.0 5.07e-01 70.7% 82.2%
3209632 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.69 47.0 4.59e-01 72.7% 63.6%
4287749 150.5.1.110 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PRESAN 0.68 48.0 5.01e-01 77.8% 80.0%
3409567 3755.3.1.324 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 0.68 51.0 4.32e-01 79.8% 86.7%
3592341 3877.1.1.0 alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC 0.68 53.0 3.98e-01 83.8% 85.0%
3524385 3881.1.1.2 alpha bundles › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › Codanin-1_C 0.64 48.0 4.10e-01 78.8% 68.8%
3590829 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.64 47.0 4.36e-01 77.8% 60.8%
3593009 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.64 46.0 5.08e-01 100.0% 93.8%
2777335 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.64 44.0 4.14e-01 72.7% 61.6%
3772061 109.4.1.809 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Codanin-1_C 0.62 47.0 3.21e-01 79.8% 30.8%
3516870 5094.1.1.0 a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like 0.62 46.0 4.55e-01 77.8% 73.3%
5030079 2002.1.1.60 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › AP_endonuc_2 0.61 52.0 3.36e-01 94.9% 35.2%
3965811 3711.1.1.0 alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.61 44.0 4.32e-01 75.8% 86.2%
3402327 3755.3.1.324 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 0.60 47.0 3.95e-01 84.8% 87.6%
3584730 3567.1.1.81 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › 7TM_GPCR_Srw 0.59 52.0 4.50e-01 98.0% 72.9%
4283243 2004.1.1.149 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SecA_DEAD 0.57 49.0 3.35e-01 92.9% 49.7%
4224436 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.56 50.0 3.71e-01 99.0% 40.4%
5026085 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.52 45.0 4.43e-01 100.0% 87.0%