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OY979411.1__CAK6605633.1__K1PH164C1_LOCUS55__00055
Bact-VirOY979411.1__CAK6605633.1__K1PH164C1_LOCUS55__00055
Identity
- Accession:
- OY979411 ↗
- Kingdom:
- phage
Quality
84.0
mean pLDDT
Taxonomy
Heunggongvirae›
Uroviricota›
Caudoviricetes›
Autographivirales›
Autoscriptoviridae›
Drulisvirus›
Klebsiella_phage_vB_Kpn_K1PH164C1
TaxID: 3071616
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 35-106
Domain cluster:
representative
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4fzlA01 | 1.10.150.790 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.59 | 40.0 | 3.74e-01 | 83.3% | 56.3% |
| 3u4qA02 | 1.10.274.50 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › | 0.56 | 47.0 | 3.79e-01 | 95.8% | 57.3% |
| 3qxlA00 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.53 | 40.0 | 2.87e-01 | 83.3% | 68.6% |
| 3zh9B03 | 1.20.272.10 | Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › | 0.51 | 43.0 | 3.67e-01 | 100.0% | 57.9% |
ECOD (6)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4198249 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.69 | 59.0 | 4.53e-01 | 100.0% | 54.4% |
| 3635261 | 5076.2.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ | 0.60 | 46.0 | 3.34e-01 | 84.7% | 57.7% |
| 3524353 | 7512.1.1.1 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT | 0.58 | 42.0 | 2.93e-01 | 79.2% | 49.8% |
| 3727244 | 633.7.1.0 ↗ | alpha bundles › Bromodomain-like › Bacillus cereus metalloprotein-like › Bacillus cereus metalloprotein-like | 0.56 | 45.0 | 3.45e-01 | 88.9% | 62.9% |
| 3421799 | 109.27.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain › NPH3 | 0.56 | 40.0 | 3.52e-01 | 81.9% | 47.8% |
| 4990792 | 247.1.1.0 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase | 0.53 | 44.0 | 3.21e-01 | 100.0% | 64.6% |
D2
medium
residues 107-182
Domain cluster:
rep: NC_030923.1__YP_009275020.1__BH776_gp02__00002__D91-188
CATH (62)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.86 | 77.0 | 6.81e-01 | 98.7% | 88.1% |
| 3fblA00 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.85 | 68.0 | 6.61e-01 | 98.7% | 78.0% |
| 5mlc900 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.83 | 76.0 | 6.70e-01 | 100.0% | 90.7% |
| 1txuA01 | 1.10.246.120 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.80 | 70.0 | 6.53e-01 | 100.0% | 77.7% |
| 1s2xA00 | 1.20.190.30 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ | 0.76 | 69.0 | 5.14e-01 | 98.7% | 67.2% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.76 | 53.0 | 5.10e-01 | 72.4% | 65.9% |
| 4zvaA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.75 | 68.0 | 5.39e-01 | 100.0% | 87.2% |
| 3q5dA02 | 1.20.58.420 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › AHSP | 0.75 | 66.0 | 6.15e-01 | 100.0% | 80.4% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.74 | 64.0 | 5.52e-01 | 98.7% | 61.2% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.73 | 64.0 | 5.33e-01 | 98.7% | 86.5% |
| 2w31A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.73 | 66.0 | 5.24e-01 | 100.0% | 83.6% |
| 4uiqB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.73 | 65.0 | 5.16e-01 | 100.0% | 86.3% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.71 | 50.0 | 5.20e-01 | 72.4% | 82.4% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.71 | 62.0 | 6.00e-01 | 100.0% | 93.1% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.70 | 48.0 | 4.74e-01 | 72.4% | 68.3% |
| 2c2uA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 58.0 | 4.43e-01 | 92.1% | 74.2% |
| 1urvA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.68 | 60.0 | 4.80e-01 | 100.0% | 89.6% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.68 | 60.0 | 4.78e-01 | 100.0% | 54.2% |
| 6o0aA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.67 | 59.0 | 4.79e-01 | 100.0% | 84.6% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 46.0 | 4.64e-01 | 75.0% | 70.1% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.67 | 58.0 | 5.24e-01 | 100.0% | 84.9% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.66 | 44.0 | 4.26e-01 | 71.1% | 59.8% |
| 2mx8A01 | 1.10.274.70 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain | 0.66 | 57.0 | 5.02e-01 | 96.1% | 64.6% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 45.0 | 4.10e-01 | 71.1% | 86.3% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.65 | 46.0 | 3.91e-01 | 73.7% | 73.8% |
| 3pmcA00 | 1.10.490.70 | Mainly Alpha › Orthogonal Bundle › Globin-like › Histidine kinase N-terminal domain | 0.65 | 55.0 | 4.72e-01 | 100.0% | 94.7% |
| 1a00B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.64 | 55.0 | 4.58e-01 | 100.0% | 91.1% |
| 1or4B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.64 | 56.0 | 4.49e-01 | 100.0% | 80.4% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.64 | 53.0 | 4.61e-01 | 93.4% | 68.3% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.64 | 55.0 | 4.17e-01 | 98.7% | 79.5% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.64 | 53.0 | 4.38e-01 | 96.1% | 90.6% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.64 | 53.0 | 4.51e-01 | 96.1% | 91.1% |
| 3ubcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.63 | 56.0 | 4.68e-01 | 100.0% | 91.6% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.63 | 43.0 | 4.13e-01 | 72.4% | 78.9% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 53.0 | 4.43e-01 | 96.1% | 91.3% |
| 1cg5B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.62 | 54.0 | 4.50e-01 | 100.0% | 92.9% |
| 1tu9A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.62 | 53.0 | 4.55e-01 | 100.0% | 93.1% |
| 2r9iA00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.62 | 43.0 | 4.40e-01 | 72.4% | 80.3% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.62 | 53.0 | 4.46e-01 | 98.7% | 71.5% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.62 | 45.0 | 4.09e-01 | 77.6% | 60.0% |
| 2iakA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 52.0 | 4.03e-01 | 100.0% | 76.0% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.61 | 51.0 | 4.30e-01 | 94.7% | 71.4% |
| 3u3iA02 | 1.20.58.1110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 50.0 | 4.58e-01 | 97.4% | 75.0% |
| 2rkkA01 | 1.25.40.270 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Vacuolar protein sorting-associated protein vta1 | 0.60 | 49.0 | 3.86e-01 | 88.2% | 72.4% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 41.0 | 3.81e-01 | 71.1% | 77.1% |
| 1bgfA00 | 1.10.532.10 | Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain | 0.60 | 49.0 | 4.29e-01 | 94.7% | 61.3% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 50.0 | 4.53e-01 | 96.1% | 92.5% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.59 | 40.0 | 3.18e-01 | 78.9% | 32.9% |
| 4q20A01 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.59 | 40.0 | 3.96e-01 | 71.1% | 68.3% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.58 | 47.0 | 4.69e-01 | 98.7% | 90.9% |
| 1yvwA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.57 | 40.0 | 3.78e-01 | 84.2% | 59.8% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.56 | 40.0 | 3.94e-01 | 88.2% | 70.4% |
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 46.0 | 4.27e-01 | 93.4% | 86.0% |
| 4fxdA04 | 3.90.1600.10 | Alpha Beta › Alpha-Beta Complex › Palm domain of DNA polymerase › B family DNA polymerase, palm domain | 0.55 | 47.0 | 3.87e-01 | 100.0% | 85.0% |
| 1kf6C00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.55 | 41.0 | 3.54e-01 | 81.6% | 71.5% |
| 4wzxA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.55 | 45.0 | 4.56e-01 | 96.1% | 96.0% |
| 2a6cA00 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.55 | 33.0 | 3.39e-01 | 93.4% | 60.5% |
| 3k17A02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.54 | 45.0 | 3.72e-01 | 92.1% | 58.6% |
| 3p42A02 | 6.10.250.2280 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.52 | 41.0 | 4.29e-01 | 84.2% | 100.0% |
| 2b5dX02 | 1.20.1430.10 | Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain | 0.52 | 46.0 | 4.04e-01 | 100.0% | 94.7% |
| 1gt0D00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.52 | 38.0 | 3.83e-01 | 78.9% | 88.6% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 45.0 | 3.20e-01 | 100.0% | 80.9% |
ECOD (55)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4030543 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.89 | 83.0 | 6.17e-01 | 100.0% | 97.1% |
| 3518051 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.84 | 78.0 | 5.71e-01 | 100.0% | 91.6% |
| 4080313 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.80 | 72.0 | 5.89e-01 | 100.0% | 88.6% |
| 3289364 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.80 | 73.0 | 5.78e-01 | 100.0% | 88.0% |
| 3955107 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.80 | 73.0 | 5.68e-01 | 100.0% | 87.1% |
| 3282048 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.78 | 71.0 | 5.71e-01 | 100.0% | 88.3% |
| 4965710 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.78 | 70.0 | 4.50e-01 | 100.0% | 28.0% |
| 4351705 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.77 | 68.0 | 6.72e-01 | 98.7% | 91.3% |
| 4565834 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.77 | 70.0 | 5.53e-01 | 98.7% | 88.0% |
| 4624818 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.77 | 69.0 | 6.52e-01 | 100.0% | 87.8% |
| 4563317 | 192.7.1.3 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N | 0.77 | 67.0 | 6.61e-01 | 96.1% | 91.3% |
| 3291430 | 106.1.1.11 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › RsbRD_N | 0.77 | 70.0 | 5.64e-01 | 100.0% | 92.1% |
| 4554328 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.75 | 67.0 | 6.39e-01 | 100.0% | 90.9% |
| 3600971 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.75 | 66.0 | 4.26e-01 | 100.0% | 22.3% |
| 3319812 | 3562.1.1.0 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 | 0.74 | 50.0 | 4.21e-01 | 71.1% | 42.4% |
| 4592728 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.73 | 66.0 | 6.25e-01 | 100.0% | 88.9% |
| 5045531 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.72 | 60.0 | 5.84e-01 | 92.1% | 82.4% |
| 3297600 | 621.1.1.7 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 | 0.72 | 63.0 | 5.80e-01 | 100.0% | 80.0% |
| 3962893 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.71 | 48.0 | 4.50e-01 | 71.1% | 57.9% |
| 3605712 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.70 | 57.0 | 5.63e-01 | 96.1% | 86.3% |
| 4445617 | 3281.1.1.1 ↗ | alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related › Proton_antipo_M | 0.70 | 61.0 | 3.76e-01 | 98.7% | 21.4% |
| 4032384 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.69 | 58.0 | 5.71e-01 | 98.7% | 90.0% |
| 3981661 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 57.0 | 5.45e-01 | 96.1% | 83.3% |
| 3903422 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.68 | 47.0 | 3.99e-01 | 71.1% | 49.2% |
| 4988301 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.67 | 58.0 | 4.76e-01 | 100.0% | 92.7% |
| 3600277 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.66 | 58.0 | 4.80e-01 | 100.0% | 90.0% |
| 3552989 | 604.8.1.1 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo › Smac_DIABLO | 0.66 | 58.0 | 4.40e-01 | 100.0% | 65.2% |
| 3607135 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.66 | 46.0 | 3.78e-01 | 72.4% | 40.7% |
| 3484742 | 3922.1.1.197 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › BBS2_hp | 0.65 | 47.0 | 4.52e-01 | 75.0% | 71.8% |
| 3170876 | 192.7.1.30 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › CUX1_N | 0.65 | 47.0 | 4.07e-01 | 75.0% | 49.6% |
| 4024626 | 545.1.2.2 ↗ | alpha bundles › Gametocyte protein Pfg27-related › Gametocyte protein Pfg27-related › Sporozoite protein UIS3 soluble domain › ETRAMP | 0.64 | 55.0 | 4.56e-01 | 100.0% | 53.8% |
| 3268032 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.64 | 54.0 | 4.74e-01 | 97.4% | 69.2% |
| 3804937 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.64 | 46.0 | 3.60e-01 | 75.0% | 40.6% |
| 3393794 | 3922.1.1.211 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DRC7_C | 0.64 | 47.0 | 3.96e-01 | 80.3% | 83.7% |
| 3548194 | 192.2.1.18 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING | 0.63 | 45.0 | 4.02e-01 | 75.0% | 55.5% |
| 4951835 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.63 | 45.0 | 3.80e-01 | 75.0% | 48.8% |
| 3519972 | 192.5.1.14 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA | 0.63 | 45.0 | 4.27e-01 | 75.0% | 83.3% |
| 3584048 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 53.0 | 5.09e-01 | 100.0% | 83.3% |
| 3608116 | 5086.1.1.177 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › KIF9 | 0.62 | 48.0 | 3.92e-01 | 84.2% | 95.2% |
| 4576287 | 3755.3.1.471 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Paralemmin | 0.62 | 44.0 | 3.50e-01 | 75.0% | 37.4% |
| 3908132 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.62 | 48.0 | 3.33e-01 | 84.2% | 92.1% |
| 5005480 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.61 | 53.0 | 4.15e-01 | 100.0% | 65.1% |
| 4982026 | 150.1.1.209 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF7121 | 0.61 | 53.0 | 4.36e-01 | 98.7% | 67.1% |
| 4142346 | 5086.1.1.87 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING | 0.60 | 43.0 | 3.82e-01 | 75.0% | 59.1% |
| 3779488 | 3755.4.1.69 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF28341 | 0.60 | 51.0 | 3.85e-01 | 98.7% | 80.5% |
| 3824276 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.60 | 42.0 | 3.22e-01 | 72.4% | 33.9% |
| 4936792 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.59 | 43.0 | 3.26e-01 | 78.9% | 31.9% |
| 5035274 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.58 | 44.0 | 3.80e-01 | 81.6% | 80.0% |
| 3239816 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.57 | 43.0 | 3.22e-01 | 80.3% | 87.5% |
| 3506727 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.56 | 39.0 | 3.40e-01 | 81.6% | 46.7% |
| 3631103 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.55 | 48.0 | 3.43e-01 | 100.0% | 35.4% |
| 4076485 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.54 | 43.0 | 4.18e-01 | 85.5% | 76.5% |
| 4383369 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.54 | 48.0 | 3.45e-01 | 100.0% | 38.2% |
| 2503462 | 601.33.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain › CHAD | 0.53 | 41.0 | 3.96e-01 | 96.1% | 73.4% |
| 3612509 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.52 | 47.0 | 3.28e-01 | 100.0% | 84.5% |
D3
medium
residues 183-260
Domain cluster:
representative
CATH (62)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3n71A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.82 | 59.0 | 4.20e-01 | 84.6% | 27.7% |
| 2pmrA00 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.79 | 53.0 | 5.42e-01 | 71.8% | 71.1% |
| 3hiuD00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.79 | 57.0 | 4.47e-01 | 76.9% | 38.2% |
| 4u1cA01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.78 | 51.0 | 6.11e-01 | 85.9% | 100.0% |
| 1rqgA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.78 | 67.0 | 5.26e-01 | 91.0% | 70.2% |
| 3pwfA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.78 | 57.0 | 4.74e-01 | 76.9% | 48.1% |
| 1j30A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.78 | 56.0 | 4.56e-01 | 76.9% | 41.8% |
| 2v0cA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.78 | 64.0 | 4.95e-01 | 87.2% | 57.9% |
| 2pihA00 | 1.20.1500.10 | Mainly Alpha › Up-down Bundle › YheA-like fold › YheA/YmcA-like | 0.77 | 53.0 | 4.48e-01 | 70.5% | 47.2% |
| 3c18A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.76 | 63.0 | 5.42e-01 | 88.5% | 84.7% |
| 4malA00 | 1.20.58.2200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 49.0 | 5.54e-01 | 83.3% | 86.4% |
| 3zc0D00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 69.0 | 5.16e-01 | 100.0% | 59.9% |
| 3nymA00 | 6.10.290.10 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.75 | 55.0 | 4.69e-01 | 76.9% | 76.6% |
| 1xnfA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.75 | 49.0 | 3.38e-01 | 82.1% | 20.5% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.75 | 67.0 | 6.16e-01 | 100.0% | 77.8% |
| 6tkvA01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.74 | 52.0 | 5.49e-01 | 73.1% | 91.2% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.74 | 52.0 | 3.97e-01 | 73.1% | 33.7% |
| 1x8zB00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.74 | 63.0 | 5.05e-01 | 92.3% | 54.4% |
| 1e2aA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.74 | 68.0 | 6.17e-01 | 100.0% | 97.1% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.74 | 69.0 | 6.21e-01 | 100.0% | 97.1% |
| 4g1tA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.74 | 52.0 | 4.46e-01 | 78.2% | 47.2% |
| 3ceqA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.73 | 51.0 | 3.49e-01 | 80.8% | 22.4% |
| 4fymF00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.73 | 61.0 | 4.46e-01 | 91.0% | 55.5% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.73 | 65.0 | 5.93e-01 | 97.4% | 94.2% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.73 | 65.0 | 5.73e-01 | 100.0% | 72.4% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.73 | 63.0 | 5.34e-01 | 92.3% | 65.3% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.72 | 56.0 | 5.69e-01 | 83.3% | 85.3% |
| 2ondA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.72 | 61.0 | 3.97e-01 | 89.7% | 35.7% |
| 1yw0A00 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.72 | 67.0 | 4.59e-01 | 100.0% | 51.0% |
| 2jbwA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.72 | 56.0 | 5.12e-01 | 83.3% | 66.0% |
| 1wolA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.71 | 54.0 | 4.59e-01 | 79.5% | 92.6% |
| 1nlxA00 | 1.20.120.320 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen | 0.71 | 57.0 | 5.19e-01 | 87.2% | 83.7% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.70 | 51.0 | 5.21e-01 | 75.6% | 85.1% |
| 1j1jA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.70 | 63.0 | 5.29e-01 | 100.0% | 72.7% |
| 2hsbA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.70 | 56.0 | 4.71e-01 | 84.6% | 91.3% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 63.0 | 4.77e-01 | 100.0% | 61.3% |
| 3iqcA00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.70 | 59.0 | 5.15e-01 | 92.3% | 75.6% |
| 3nkzA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.70 | 56.0 | 5.16e-01 | 84.6% | 80.4% |
| 6adqG01 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.70 | 61.0 | 4.69e-01 | 97.4% | 68.5% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.70 | 63.0 | 5.67e-01 | 100.0% | 78.3% |
| 3dzaA01 | 1.20.120.1940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain | 0.69 | 58.0 | 4.98e-01 | 89.7% | 83.8% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.68 | 54.0 | 4.71e-01 | 92.3% | 56.9% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 53.0 | 4.19e-01 | 83.3% | 56.3% |
| 2fbnA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.67 | 55.0 | 4.36e-01 | 87.2% | 64.7% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 48.0 | 5.34e-01 | 83.3% | 92.1% |
| 5o5jT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.67 | 60.0 | 5.88e-01 | 100.0% | 90.6% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.67 | 58.0 | 5.45e-01 | 97.4% | 97.9% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.67 | 54.0 | 5.28e-01 | 84.6% | 90.4% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.67 | 54.0 | 5.46e-01 | 85.9% | 89.6% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 53.0 | 4.84e-01 | 85.9% | 64.8% |
| 1q0gA00 | 1.20.120.400 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase | 0.66 | 56.0 | 4.89e-01 | 92.3% | 76.1% |
| 4ebjA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.66 | 51.0 | 4.30e-01 | 82.1% | 99.2% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.66 | 57.0 | 5.26e-01 | 92.3% | 76.3% |
| 3gw4A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.66 | 52.0 | 3.81e-01 | 83.3% | 48.4% |
| 4u7iA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.65 | 58.0 | 5.42e-01 | 96.2% | 100.0% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.64 | 47.0 | 4.45e-01 | 76.9% | 67.7% |
| 2rpaA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.63 | 51.0 | 5.13e-01 | 87.2% | 90.9% |
| 2hfsA02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.63 | 55.0 | 4.36e-01 | 93.6% | 79.5% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 54.0 | 5.06e-01 | 100.0% | 98.0% |
| 5mmjo00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.61 | 46.0 | 4.70e-01 | 80.8% | 92.0% |
| 1nafA02 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 48.0 | 4.74e-01 | 89.7% | 96.5% |
| 1e3mB04 | 1.10.1420.10 | Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › | 0.55 | 43.0 | 3.56e-01 | 87.2% | 80.9% |
ECOD (75)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4534445 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.93 | 66.0 | 6.25e-01 | 73.1% | 64.4% |
| 3287070 | 605.1.1.4 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 | 0.89 | 63.0 | 5.86e-01 | 73.1% | 61.1% |
| 4426045 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.88 | 62.0 | 4.93e-01 | 73.1% | 40.7% |
| 3600184 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.88 | 62.0 | 4.97e-01 | 73.1% | 42.1% |
| 3292425 | 3291.1.1.4 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 | 0.87 | 63.0 | 4.45e-01 | 76.9% | 28.3% |
| 4962838 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.86 | 64.0 | 4.50e-01 | 76.9% | 28.4% |
| 3560750 | 192.17.1.0 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like | 0.84 | 62.0 | 6.59e-01 | 76.9% | 88.6% |
| 4972186 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.84 | 60.0 | 4.96e-01 | 76.9% | 44.6% |
| 5051493 | 109.3.1.473 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › TPR_8 | 0.83 | 69.0 | 4.56e-01 | 93.6% | 24.3% |
| 3940514 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.83 | 59.0 | 4.63e-01 | 73.1% | 39.3% |
| 4809272 | 3291.1.1.4 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 | 0.82 | 59.0 | 4.99e-01 | 76.9% | 47.9% |
| 3576866 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.82 | 61.0 | 4.46e-01 | 76.9% | 38.9% |
| 4437441 | 109.4.1.1333 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35, PF27614 | 0.79 | 71.0 | 4.66e-01 | 97.4% | 25.0% |
| 3551692 | 109.4.1.44 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35 | 0.79 | 71.0 | 4.01e-01 | 97.4% | 9.5% |
| 3652677 | 601.18.1.13 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Vwaint | 0.79 | 68.0 | 5.85e-01 | 91.0% | 85.2% |
| 3586131 | 109.4.1.1333 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35, PF27614 | 0.79 | 73.0 | 4.09e-01 | 100.0% | 9.8% |
| 3229748 | 1134.1.1.9 ↗ | alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain › RSLD_CPSF6 | 0.78 | 71.0 | 6.89e-01 | 96.2% | 88.2% |
| 4026965 | 109.4.1.64 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › GET4 | 0.78 | 57.0 | 3.83e-01 | 87.2% | 21.9% |
| 5041256 | 601.4.1.91 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › PF30769 | 0.78 | 66.0 | 5.92e-01 | 89.7% | 85.7% |
| 3773905 | 604.3.1.33 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › RSLD_CPSF6 | 0.78 | 69.0 | 7.02e-01 | 93.6% | 97.3% |
| 3924801 | 109.4.1.1643 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RSLD_CPSF6 | 0.77 | 73.0 | 6.74e-01 | 100.0% | 82.1% |
| 3309583 | 604.12.1.65 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT_ATG1 | 0.77 | 60.0 | 6.02e-01 | 82.1% | 91.3% |
| 3504528 | 109.4.1.1333 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps35, PF27614 | 0.77 | 69.0 | 4.18e-01 | 97.4% | 16.4% |
| 4993041 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.77 | 57.0 | 5.69e-01 | 76.9% | 78.8% |
| 4019540 | 109.4.1.862 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ZW10_C2 | 0.77 | 71.0 | 4.12e-01 | 100.0% | 12.5% |
| 3249529 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.76 | 62.0 | 5.08e-01 | 85.9% | 80.0% |
| 3574981 | 604.12.1.91 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › RSLD_CPSF6 | 0.76 | 61.0 | 6.42e-01 | 84.6% | 94.3% |
| 3633107 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.76 | 66.0 | 6.11e-01 | 92.3% | 88.4% |
| 3528802 | 109.4.1.2773 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_8, TPR_10, TPR_12, TPR_16 | 0.76 | 70.0 | 4.20e-01 | 100.0% | 28.1% |
| 5050919 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.75 | 67.0 | 5.93e-01 | 97.4% | 97.3% |
| 3208696 | 109.4.1.2122 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Zw10_middle, ZW10_C2 | 0.75 | 70.0 | 4.06e-01 | 100.0% | 13.1% |
| 4202852 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.75 | 70.0 | 6.24e-01 | 100.0% | 75.2% |
| 3456188 | 109.7.1.10 ↗ | alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E › WAV3_C | 0.75 | 59.0 | 6.02e-01 | 91.0% | 85.3% |
| 1822946 | 109.4.1.292 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › eIF3a_PCI_TPR-like | 0.75 | 55.0 | 4.09e-01 | 91.0% | 31.6% |
| 4172303 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.75 | 70.0 | 5.86e-01 | 100.0% | 63.2% |
| 4996465 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.75 | 64.0 | 4.68e-01 | 93.6% | 78.5% |
| 3407072 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.74 | 59.0 | 5.93e-01 | 84.6% | 87.5% |
| 4927814 | 109.10.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Translin › Translin › Translin | 0.74 | 68.0 | 4.89e-01 | 100.0% | 54.8% |
| 3978919 | 604.10.1.1 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PTS_IIA | 0.74 | 69.0 | 6.06e-01 | 100.0% | 90.0% |
| 4968405 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.74 | 63.0 | 5.50e-01 | 94.9% | 63.6% |
| 5033222 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.74 | 66.0 | 5.92e-01 | 100.0% | 71.4% |
| 5005597 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.73 | 65.0 | 5.40e-01 | 98.7% | 87.4% |
| 3615671 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.73 | 65.0 | 4.57e-01 | 100.0% | 33.1% |
| 3175425 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.72 | 64.0 | 4.78e-01 | 97.4% | 58.4% |
| 4978586 | 604.9.1.0 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 | 0.72 | 62.0 | 5.53e-01 | 100.0% | 67.3% |
| 5038830 | 375.1.1.26 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 | 0.72 | 62.0 | 5.67e-01 | 100.0% | 72.0% |
| 3940649 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.71 | 54.0 | 5.38e-01 | 79.5% | 81.2% |
| 3988387 | 604.10.1.1 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PTS_IIA | 0.71 | 64.0 | 5.85e-01 | 96.2% | 96.0% |
| 4032446 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.71 | 51.0 | 5.22e-01 | 74.4% | 85.3% |
| 5024797 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.71 | 53.0 | 5.75e-01 | 79.5% | 98.5% |
| 5072045 | 604.10.1.0 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac | 0.71 | 63.0 | 5.65e-01 | 96.2% | 82.9% |
| 3262611 | 109.20.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Coatomer subunit alpha C-terminal domain › Coatomer subunit alpha C-terminal domain › COPI_C | 0.71 | 63.0 | 4.77e-01 | 98.7% | 64.9% |
| 3246163 | 109.4.1.1286 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_12 | 0.71 | 64.0 | 4.17e-01 | 100.0% | 33.4% |
| 3610794 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.70 | 61.0 | 4.38e-01 | 100.0% | 69.8% |
| 3995816 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.70 | 57.0 | 5.59e-01 | 88.5% | 80.0% |
| 5062478 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.70 | 65.0 | 6.17e-01 | 100.0% | 92.2% |
| 3354926 | 9001.1.1.1 ↗ | alpha bundles › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TMEM120/ELO/TLC › TRAM_LAG1_CLN8 | 0.70 | 56.0 | 4.87e-01 | 87.2% | 86.7% |
| 3737384 | 109.4.1.3501 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Nro1, Nro1_C | 0.70 | 57.0 | 3.72e-01 | 91.0% | 75.3% |
| 4996375 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.69 | 64.0 | 4.92e-01 | 100.0% | 90.9% |
| 4945785 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.69 | 65.0 | 4.86e-01 | 100.0% | 88.0% |
| 3425296 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.69 | 64.0 | 5.22e-01 | 100.0% | 91.1% |
| 3821843 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.69 | 64.0 | 5.00e-01 | 100.0% | 92.3% |
| 4099511 | 109.4.1.228 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Exo84_C | 0.68 | 59.0 | 4.04e-01 | 92.3% | 29.3% |
| 3660443 | 604.6.1.40 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › PF27980 | 0.68 | 58.0 | 5.56e-01 | 96.2% | 97.8% |
| 4027146 | 109.4.1.362 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1,TPR_8 | 0.68 | 56.0 | 4.20e-01 | 87.2% | 53.1% |
| 3708191 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.68 | 49.0 | 5.00e-01 | 75.6% | 80.0% |
| 59849 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 55.0 | 4.37e-01 | 87.2% | 63.3% |
| 3441821 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.67 | 59.0 | 4.75e-01 | 97.4% | 73.3% |
| 4427487 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.67 | 59.0 | 5.64e-01 | 100.0% | 86.7% |
| 3686432 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.66 | 59.0 | 4.36e-01 | 97.4% | 40.0% |
| 5075122 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.66 | 61.0 | 5.03e-01 | 98.7% | 96.2% |
| 5056592 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 59.0 | 3.76e-01 | 98.7% | 88.9% |
| 3192973 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 57.0 | 4.00e-01 | 100.0% | 72.3% |
| 3425962 | 603.1.1.116 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27980 | 0.64 | 53.0 | 5.25e-01 | 94.9% | 100.0% |
| 4969009 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 51.0 | 4.32e-01 | 85.9% | 73.6% |
D4
medium
residues 261-378
Domain cluster:
representative
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.80 | 55.0 | 5.81e-01 | 71.2% | 100.0% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.79 | 62.0 | 5.54e-01 | 82.2% | 96.3% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 43.0 | 4.58e-01 | 94.1% | 61.8% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 55.0 | 5.47e-01 | 73.7% | 100.0% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.76 | 54.0 | 5.80e-01 | 72.9% | 87.9% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.75 | 55.0 | 5.57e-01 | 76.3% | 97.4% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.73 | 51.0 | 5.21e-01 | 89.8% | 73.3% |
| 5mdtA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.73 | 49.0 | 4.47e-01 | 84.7% | 52.6% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 50.0 | 4.83e-01 | 71.2% | 83.1% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.70 | 49.0 | 4.67e-01 | 72.0% | 77.4% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.69 | 51.0 | 5.09e-01 | 76.3% | 96.6% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.69 | 45.0 | 5.35e-01 | 91.5% | 100.0% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 43.0 | 3.90e-01 | 96.6% | 46.6% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 40.0 | 4.29e-01 | 94.9% | 69.0% |
| 7e5aB02 | 1.20.1000.10 | Mainly Alpha › Up-down Bundle › Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1 › Guanylate-binding protein, C-terminal domain | 0.67 | 53.0 | 4.76e-01 | 84.7% | 82.3% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.65 | 54.0 | 4.86e-01 | 90.7% | 98.2% |
| 7dswA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.63 | 51.0 | 3.49e-01 | 85.6% | 24.9% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.63 | 51.0 | 4.25e-01 | 86.4% | 59.4% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.62 | 48.0 | 3.56e-01 | 80.5% | 70.0% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.62 | 37.0 | 4.22e-01 | 84.7% | 81.9% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 48.0 | 5.03e-01 | 88.1% | 100.0% |
| 4i4cB00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.58 | 46.0 | 3.18e-01 | 84.7% | 35.7% |
| 3rauA00 | 1.25.40.280 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › alix/aip1 like domains | 0.58 | 48.0 | 3.46e-01 | 91.5% | 87.7% |
| 2wzkA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.56 | 43.0 | 4.47e-01 | 83.1% | 90.0% |
| 3uumA00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 48.0 | 4.83e-01 | 94.9% | 98.4% |
| 1ldjA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.55 | 41.0 | 4.22e-01 | 83.9% | 82.6% |
| 4h3tA02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.54 | 39.0 | 3.75e-01 | 75.4% | 83.7% |
| 3fnbA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.52 | 42.0 | 4.31e-01 | 84.7% | 95.6% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3345061 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.82 | 56.0 | 5.10e-01 | 70.3% | 84.5% |
| 3616671 | 604.1.1.155 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF29142 | 0.80 | 59.0 | 6.49e-01 | 75.4% | 100.0% |
| 4227989 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.78 | 54.0 | 6.17e-01 | 71.2% | 95.5% |
| 3554294 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.77 | 61.0 | 5.03e-01 | 82.2% | 84.5% |
| 4290271 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.77 | 57.0 | 6.40e-01 | 83.9% | 100.0% |
| 3957298 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.77 | 54.0 | 6.11e-01 | 72.9% | 94.4% |
| 3900969 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.76 | 53.0 | 5.44e-01 | 72.0% | 99.1% |
| 4201754 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.76 | 55.0 | 6.01e-01 | 76.3% | 92.6% |
| 3387995 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.75 | 52.0 | 4.32e-01 | 71.2% | 82.0% |
| 4470760 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.75 | 56.0 | 4.27e-01 | 78.8% | 70.7% |
| 3782089 | 1065.1.1.0 ↗ | alpha bundles › SPX domain › SPX domain › SPX domain | 0.74 | 60.0 | 5.33e-01 | 85.6% | 89.7% |
| 3330505 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.74 | 51.0 | 5.57e-01 | 71.2% | 99.0% |
| 3463676 | 109.4.1.1186 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF6857 | 0.73 | 54.0 | 4.95e-01 | 77.1% | 62.6% |
| 4321884 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.73 | 54.0 | 5.96e-01 | 84.7% | 96.8% |
| 3499075 | 109.4.1.445 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps54_N | 0.73 | 66.0 | 4.35e-01 | 100.0% | 48.2% |
| 3378097 | 604.1.1.110 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › WIT1_2_N | 0.72 | 51.0 | 5.14e-01 | 72.9% | 100.0% |
| 5005480 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.71 | 54.0 | 4.74e-01 | 80.5% | 82.3% |
| 3897356 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.70 | 54.0 | 4.45e-01 | 81.4% | 72.4% |
| 3989466 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.70 | 57.0 | 3.61e-01 | 88.1% | 58.2% |
| 4526671 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.70 | 56.0 | 4.38e-01 | 85.6% | 92.0% |
| 3973330 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 50.0 | 4.27e-01 | 74.6% | 63.8% |
| 3596026 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.69 | 52.0 | 4.85e-01 | 79.7% | 99.3% |
| 5000552 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.69 | 43.0 | 4.62e-01 | 85.6% | 73.0% |
| 3246566 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.68 | 54.0 | 4.61e-01 | 83.9% | 70.0% |
| 3884665 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.68 | 54.0 | 5.15e-01 | 85.6% | 100.0% |
| 3733444 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.67 | 47.0 | 3.32e-01 | 72.9% | 94.3% |
| 3936985 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.64 | 50.0 | 4.52e-01 | 81.4% | 80.0% |
| 3815122 | 604.12.1.68 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DUF6857 | 0.64 | 52.0 | 4.56e-01 | 89.0% | 71.1% |
| 3377896 | 109.4.1.588 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › FPL | 0.61 | 50.0 | 3.61e-01 | 88.1% | 71.9% |
| 5012794 | 4333.1.1.0 ↗ | a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain | 0.59 | 39.0 | 2.77e-01 | 72.9% | 22.0% |
| 3609309 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 46.0 | 3.72e-01 | 83.1% | 84.4% |
| 4179150 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.58 | 47.0 | 3.04e-01 | 85.6% | 46.2% |
| 3630440 | 109.4.1.1328 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF26034 | 0.57 | 44.0 | 4.50e-01 | 82.2% | 88.7% |
| 3579748 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.54 | 45.0 | 3.98e-01 | 100.0% | 61.8% |
| 3252293 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.52 | 45.0 | 3.30e-01 | 96.6% | 45.5% |
D5
medium
residues 379-517
Domain cluster:
representative
CATH (15)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3tm8B00 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.66 | 56.0 | 4.34e-01 | 92.1% | 64.5% |
| 4c0eA02 | 1.25.40.800 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.65 | 48.0 | 4.07e-01 | 75.5% | 56.9% |
| 4by6A01 | 1.25.40.790 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.64 | 49.0 | 3.91e-01 | 79.9% | 68.2% |
| 5m9dA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.59 | 43.0 | 4.33e-01 | 74.8% | 85.5% |
| 1e7pC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.59 | 42.0 | 3.40e-01 | 71.9% | 82.7% |
| 5d1rB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 48.0 | 4.09e-01 | 89.9% | 96.9% |
| 3hl6A02 | 1.20.58.700 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 37.0 | 4.02e-01 | 79.9% | 81.7% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 38.0 | 4.30e-01 | 71.2% | 99.1% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.55 | 39.0 | 3.57e-01 | 72.7% | 56.5% |
| 4j8sA00 | 1.25.40.840 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › CCR4-NOT transcription complex subunit 1 TTP binding domain | 0.55 | 45.0 | 4.18e-01 | 88.5% | 81.1% |
| 1k8kG00 | 1.25.40.190 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Actin-related protein 2/3 complex subunit 5 | 0.55 | 41.0 | 4.19e-01 | 79.9% | 81.3% |
| 4ap2B01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.54 | 40.0 | 4.11e-01 | 77.0% | 95.5% |
| 3bniB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 44.0 | 4.13e-01 | 90.6% | 100.0% |
| 5xjnA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.51 | 36.0 | 2.66e-01 | 72.7% | 75.7% |
| 1n4kA02 | 1.25.10.30 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › IP3 receptor type 1 binding core, RIH domain | 0.51 | 45.0 | 4.41e-01 | 97.1% | 97.3% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3456183 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.71 | 47.0 | 5.39e-01 | 72.7% | 92.0% |
| 3226817 | 109.4.1.1428 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Edg1 | 0.63 | 47.0 | 3.66e-01 | 79.1% | 49.8% |
| 3931268 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 47.0 | 3.99e-01 | 84.2% | 65.8% |
| 3583269 | 109.4.1.266 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › XMAP215_CLASP_TOG | 0.58 | 48.0 | 3.16e-01 | 89.2% | 44.0% |
| 3055994 | 601.4.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 | 0.58 | 41.0 | 3.93e-01 | 73.4% | 67.1% |
| 3183367 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.57 | 45.0 | 3.65e-01 | 84.9% | 80.7% |
| 3788234 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.55 | 48.0 | 3.34e-01 | 95.7% | 62.6% |
| 3610403 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.54 | 38.0 | 3.66e-01 | 71.9% | 74.1% |
| 3226285 | 109.4.1.266 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › XMAP215_CLASP_TOG | 0.54 | 43.0 | 3.88e-01 | 85.6% | 71.3% |
| None | — | 0.53 | 46.0 | 3.60e-01 | 95.0% | 52.3% | |
| 3394762 | 188.1.1.0 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain | 0.51 | 38.0 | 3.52e-01 | 75.5% | 68.8% |
| 3847817 | 109.25.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › GAIN | 0.51 | 39.0 | 4.29e-01 | 82.7% | 99.1% |
| 4935725 | 3684.1.1.0 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like | 0.50 | 38.0 | 3.93e-01 | 91.4% | 82.2% |
| 5043160 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 38.0 | 3.25e-01 | 82.7% | 48.4% |
| 4978004 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.50 | 38.0 | 3.44e-01 | 79.9% | 59.5% |
D6
medium
residues 708-893
Domain cluster:
rep: OM362522.1__UPO38812.1__GHSM17_11__00011__D182-363