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P1192R
Euk-VirAfrican_swine_fever_virus
P1192R__YP_009703168__African_swine_fever_virus__10497
Identity
- Accession:
- YP_009703168 ↗
- Protein ID:
- P1192R
- Kingdom:
- euk
Quality
77.4
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Asfuvirales›
Asfarviridae›
Asfivirus›
African_swine_fever_virus
TaxID: 10497
Cluster
View cluster (39 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 418-575_614-655
D2
high
residues 708-846
Domain cluster:
rep: DNA_topoisomerase_2__YP_009162467__Salmon_gill_poxvirus__1680908__D669-796
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 96.5 | 2.40e-27 | 100.0% | 30.6% |
D3
high
residues 899-1009
Domain cluster:
rep: IMGVR_UViG_3300007985_000017-3300007985-Ga0100381_100027569__D212-299
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00521.27 best | DNA_topoisoIV | 36.3 | 4.30e-09 | 97.3% | 24.1% |
D4
high
residues 1035-1160
D5
medium
residues 31-98_197-249
Domain cluster:
rep: topoisomerase_II__YP_009702678__African_swine_fever_virus__10497__D58-99_191-247
D6
medium
residues 99-196
Domain cluster:
rep: GyrB-like_ATPase_domain_protein__YP_784274__Nile_crocodilepox_virus__1285600__D74-178
CATH (10)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1pvgA01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.91 | 86.0 | 6.15e-01 | 100.0% | 39.3% |
| 1s14B00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.84 | 59.0 | 4.72e-01 | 100.0% | 39.9% |
| 1aj6A00 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.79 | 61.0 | 4.79e-01 | 100.0% | 41.2% |
| 1b63A01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.76 | 62.0 | 4.70e-01 | 100.0% | 39.4% |
| 1h7sA01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.70 | 51.0 | 4.04e-01 | 100.0% | 38.9% |
| 3cwvA01 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.65 | 54.0 | 4.26e-01 | 100.0% | 43.9% |
| 2cuhA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 33.0 | 3.43e-01 | 93.9% | 70.5% |
| 2dleA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 31.0 | 3.33e-01 | 94.9% | 68.6% |
| 2lgnA00 | 2.60.40.2850 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.51 | 30.0 | 3.52e-01 | 100.0% | 86.4% |
| 7sf2A02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.51 | 35.0 | 3.60e-01 | 94.9% | 74.2% |
ECOD (38)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4875911 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.99 | 96.0 | 6.70e-01 | 100.0% | 37.5% |
| 4617838 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.92 | 86.0 | 6.14e-01 | 100.0% | 38.8% |
| 3594649 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.92 | 85.0 | 6.10e-01 | 100.0% | 38.8% |
| 3998214 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.91 | 85.0 | 6.03e-01 | 100.0% | 37.3% |
| 3789605 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.90 | 86.0 | 6.15e-01 | 100.0% | 39.6% |
| 3198261 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.88 | 85.0 | 6.56e-01 | 100.0% | 55.8% |
| 1223478 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.87 | 76.0 | 5.37e-01 | 100.0% | 34.2% |
| 1223480 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.86 | 76.0 | 5.76e-01 | 100.0% | 44.1% |
| 3959843 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.85 | 76.0 | 5.49e-01 | 100.0% | 38.3% |
| 4038381 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.84 | 76.0 | 5.67e-01 | 100.0% | 41.8% |
| 4945731 | 225.1.1.38 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › DNA_gyraseB | 0.84 | 76.0 | 5.58e-01 | 100.0% | 40.9% |
| 4421199 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.83 | 78.0 | 5.64e-01 | 100.0% | 46.5% |
| 4027049 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.82 | 77.0 | 5.46e-01 | 100.0% | 37.5% |
| 4943430 | 225.1.1.39 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › DNA_mis_repair | 0.81 | 66.0 | 5.24e-01 | 100.0% | 45.4% |
| 4107504 | 225.1.1.3 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c | 0.80 | 64.0 | 4.85e-01 | 100.0% | 38.1% |
| 4284803 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.78 | 54.0 | 4.96e-01 | 72.4% | 56.0% |
| 3698469 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.78 | 65.0 | 4.84e-01 | 100.0% | 37.8% |
| 3321967 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.78 | 65.0 | 4.90e-01 | 100.0% | 39.5% |
| 3461648 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.78 | 74.0 | 5.36e-01 | 100.0% | 41.2% |
| 3530518 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.77 | 65.0 | 5.02e-01 | 100.0% | 44.0% |
| None | — | 0.72 | 61.0 | 4.74e-01 | 100.0% | 43.3% | |
| 3487863 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.69 | 64.0 | 4.52e-01 | 100.0% | 48.0% |
| None | — | 0.69 | 63.0 | 4.50e-01 | 100.0% | 46.9% | |
| 5027973 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.68 | 63.0 | 4.86e-01 | 100.0% | 48.3% |
| 4000208 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.68 | 62.0 | 4.59e-01 | 100.0% | 40.0% |
| 3521361 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.67 | 61.0 | 4.37e-01 | 100.0% | 46.2% |
| None | — | 0.66 | 61.0 | 4.63e-01 | 100.0% | 45.5% | |
| 5002020 | 884.1.1.0 ↗ | a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain | 0.66 | 49.0 | 4.65e-01 | 100.0% | 66.1% |
| 5019992 | 884.1.1.0 ↗ | a+b two layers › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain › Hypothetical protein YjiA, C-terminal domain | 0.65 | 48.0 | 4.57e-01 | 100.0% | 66.1% |
| 3671182 | 225.1.1.7 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 | 0.64 | 58.0 | 4.10e-01 | 100.0% | 43.3% |
| 5014685 | 243.3.1.0 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin | 0.58 | 32.0 | 3.90e-01 | 90.8% | 83.1% |
| 3996256 | 12.6.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycoside hydrolase family 127 middle domain-related › Glycoside hydrolase family 127 middle domain-related | 0.58 | 32.0 | 3.65e-01 | 91.8% | 72.9% |
| 4028905 | 225.1.1.0 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 0.57 | 53.0 | 4.02e-01 | 100.0% | 55.3% |
| 3984980 | 2484.1.1.88 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › ParM_N | 0.56 | 42.0 | 3.48e-01 | 78.6% | 92.1% |
| 3942280 | 2484.1.1.88 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › ParM_N | 0.56 | 41.0 | 3.35e-01 | 76.5% | 89.4% |
| 4122018 | 4099.1.1.10 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Med1 | 0.51 | 32.0 | 3.25e-01 | 84.7% | 61.0% |
| 184770 | 3370.1.1.1 ↗ | beta sandwiches › Lactococcin 972 › Lactococcin 972 › Lactococcin 972 › Lactococcin_972 | 0.51 | 30.0 | 3.52e-01 | 100.0% | 86.4% |
| 4095799 | 2484.1.1.0 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like | 0.51 | 45.0 | 3.28e-01 | 98.0% | 89.8% |
D7
medium
residues 250-414
Domain cluster:
rep: topoisomerase_IIA__YP_009001040__Pithovirus_sibericum__1450746__D250-321_335-390
D8
medium
residues 656-707
Domain cluster:
rep: pP1192R__YP_009703385__African_swine_fever_virus__10497__D657-707