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P3_protein

Euk-Vir

Brugmansia_mosaic_virus

P3_protein__YP_007354890__Brugmansia_mosaic_virus__1239452

Identity

Accession:
YP_007354890 ↗
Protein ID:
P3_protein
Kingdom:
euk

Quality

76.7 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Stelpaviricetes› Patatavirales› Potyviridae› Potyvirus› Brugmansia_mosaic_virus

TaxID: 1239452

Cluster

View cluster (66 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 31-191
PDB
Domain cluster: rep: P3__YP_009509100__Daphne_virus_Y__282712__D3-191
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF13608.11 best Potyvirid-P3 130.0 1.90e-37 95.7% 33.9%
D2 medium residues 314-366
PDB
Domain cluster: rep: P3_protein__YP_001816828__Telosma_mosaic_virus__400394__D286-347
CATH (38)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2nr7A00 1.20.141.10 Mainly Alpha › Up-down Bundle › Chitosanase, subunit A; domain 1 › Chitosanase, subunit A, domain 1 0.83 65.0 4.30e-01 92.5% 22.7%
1txuA02 1.20.1050.80 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › VPS9 domain 0.77 65.0 4.55e-01 92.5% 46.3%
2eucA00 1.10.8.570 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Hypothetical protein YfmB 0.77 66.0 5.20e-01 96.2% 50.5%
1ku2A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.76 61.0 5.97e-01 96.2% 82.5%
2oxlA00 1.20.5.5260 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.72 62.0 5.93e-01 100.0% 100.0%
1bdp002 1.20.1060.10 Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 0.71 60.0 4.70e-01 92.5% 76.1%
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.71 61.0 5.11e-01 100.0% 64.9%
1l0oC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.70 54.0 5.34e-01 94.3% 80.7%
3ilkA02 1.10.8.590 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.70 48.0 4.40e-01 83.0% 55.9%
4bqqB02 3.90.1750.20 Alpha Beta › Alpha-Beta Complex › Hect, E3 ligase catalytic domain fold › Putative Large Serine Recombinase; Chain B, Domain 2 0.69 48.0 3.28e-01 73.6% 20.5%
2ma3A00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.69 56.0 4.77e-01 90.6% 56.8%
2mhhA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.69 58.0 4.89e-01 100.0% 55.2%
3v9rA00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.69 57.0 4.79e-01 98.1% 54.5%
5y27A00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.68 60.0 4.91e-01 100.0% 56.1%
1gvfB00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.67 52.0 3.26e-01 83.0% 22.9%
6muwK00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.67 58.0 3.97e-01 100.0% 40.0%
6muwB00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.67 58.0 3.82e-01 100.0% 34.9%
1wtyA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.66 55.0 4.30e-01 92.5% 47.4%
6e5bN00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.66 58.0 3.93e-01 100.0% 37.7%
4ye6A02 1.10.10.2420 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.66 50.0 4.95e-01 84.9% 84.5%
3a98B01 6.10.10.90 Special › Helix non-globular › Helicase, Ruva Protein; domain 3 › 0.65 47.0 4.16e-01 79.2% 58.0%
3u9rB02 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.65 49.0 3.17e-01 84.9% 27.0%
2m4eA00 1.20.120.1930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF16691 family 0.64 47.0 4.00e-01 79.2% 70.9%
4ixjA02 3.30.1690.20 Alpha Beta › 2-Layer Sandwich › TcpA-like pilin › 0.64 56.0 4.10e-01 100.0% 81.0%
2cr7A01 1.20.1160.11 Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix 0.63 50.0 4.74e-01 88.7% 95.2%
2i7uA00 6.10.250.1010 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.61 47.0 4.49e-01 84.9% 75.8%
2v8pA01 3.30.230.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › 0.61 48.0 3.53e-01 90.6% 86.5%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.61 50.0 5.17e-01 90.6% 92.2%
6tkvA01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 50.0 4.62e-01 92.5% 72.1%
2daxA01 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.59 41.0 3.17e-01 79.2% 29.1%
1ihuA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.58 42.0 2.78e-01 77.4% 31.0%
4jd9G00 1.10.238.20 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Pheromone/general odorant binding protein domain 0.58 47.0 3.68e-01 92.5% 44.2%
1f8uA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 47.0 2.79e-01 100.0% 27.7%
5deqB02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.57 40.0 3.56e-01 86.8% 48.2%
2hh7A00 1.20.58.1000 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Metal-sensitive repressor, helix protomer 0.55 49.0 4.18e-01 100.0% 94.1%
3n54B03 3.30.300.210 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › Nutrient germinant receptor protein C, domain 3 0.54 43.0 3.26e-01 90.6% 57.3%
2reoA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.53 41.0 2.81e-01 86.8% 71.5%
4z4qA04 1.10.268.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase; domain 3 › Topoisomerase, domain 3 0.51 41.0 3.62e-01 98.1% 57.3%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5063967 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.84 67.0 6.42e-01 96.2% 75.0%
4452303 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.83 64.0 6.00e-01 96.2% 67.7%
3664504 142.1.1.3 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.81 67.0 4.66e-01 96.2% 29.7%
3668668 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.81 68.0 4.97e-01 96.2% 37.6%
None — 0.81 67.0 4.71e-01 96.2% 31.3%
3459967 142.1.1.0 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.81 67.0 5.02e-01 96.2% 39.8%
3662896 101.1.1.411 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r2 0.80 66.0 4.90e-01 96.2% 37.6%
4452096 142.1.1.1 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r1_2,Sigma70_r2 0.80 70.0 4.66e-01 96.2% 46.7%
2807554 101.1.1.27 ↗ alpha arrays › HTH › HTH › Three-helical HTH › DsrC 0.79 68.0 5.39e-01 94.3% 52.4%
5067843 101.35.1.0 ↗ alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.79 62.0 6.43e-01 88.7% 90.0%
3831185 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.79 63.0 5.71e-01 86.8% 100.0%
4339699 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.78 63.0 6.25e-01 96.2% 85.5%
4148139 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.78 59.0 4.22e-01 96.2% 28.4%
3297365 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.78 62.0 4.35e-01 96.2% 27.8%
4056602 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.77 60.0 4.12e-01 96.2% 25.7%
4550123 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.77 61.0 5.94e-01 96.2% 78.3%
3881313 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.77 58.0 5.42e-01 92.5% 66.2%
3347305 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.77 61.0 4.33e-01 96.2% 28.5%
3280166 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.77 61.0 5.91e-01 96.2% 78.3%
3429968 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.76 61.0 5.61e-01 96.2% 67.1%
4253264 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.76 63.0 5.56e-01 94.3% 64.0%
2056486 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.76 61.0 6.05e-01 96.2% 85.5%
3826046 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.76 60.0 4.25e-01 94.3% 28.5%
3303765 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.75 57.0 4.08e-01 96.2% 27.5%
3978620 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.75 58.0 4.09e-01 96.2% 27.3%
4029754 605.1.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.75 64.0 5.45e-01 94.3% 84.7%
3644937 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.75 60.0 4.29e-01 96.2% 29.4%
3943035 639.2.1.0 ↗ alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) 0.75 65.0 6.11e-01 100.0% 93.8%
2435 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.75 60.0 5.34e-01 96.2% 61.0%
3948820 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.75 59.0 5.01e-01 94.3% 52.2%
4253265 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.75 57.0 4.03e-01 96.2% 27.3%
3980765 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.74 57.0 4.03e-01 96.2% 27.3%
3350525 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.74 59.0 5.58e-01 96.2% 72.3%
3599791 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.74 62.0 3.76e-01 98.1% 15.5%
4076621 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.74 60.0 6.21e-01 92.5% 94.0%
3329805 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.74 60.0 4.22e-01 96.2% 29.4%
3311634 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.74 56.0 5.55e-01 96.2% 80.0%
3626040 109.4.1.1429 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med12, Med12-LCEWAV 0.74 64.0 3.89e-01 98.1% 27.4%
3971933 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.74 63.0 5.84e-01 94.3% 75.4%
4086835 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.74 57.0 4.98e-01 96.2% 56.2%
3989035 4230.1.1.3 ↗ alpha arrays › DnaD domain › DnaD domain › DnaD domain › DnaB_2 0.74 53.0 4.34e-01 83.0% 42.1%
4131842 101.1.3.25 ↗ alpha arrays › HTH › HTH › tetra-helical, LuxR-like › Sigma70_r3 0.73 63.0 5.56e-01 94.3% 66.7%
4388780 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.73 58.0 4.25e-01 94.3% 32.4%
3690556 148.1.1.0 ↗ alpha arrays › Histone-like › Histone-related › Histone 0.72 52.0 5.05e-01 79.2% 68.3%
3512559 192.1.1.37 ↗ alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › DUF7753 0.71 53.0 4.97e-01 79.2% 73.8%
4876273 101.1.1.29 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3 0.71 55.0 5.15e-01 96.2% 68.7%
5054485 5055.1.1.0 ↗ extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel 0.70 59.0 5.12e-01 92.5% 96.2%
None — 0.69 59.0 3.50e-01 100.0% 58.6%
3480784 148.1.1.18 ↗ alpha arrays › Histone-like › Histone-related › Histone › CENP-S 0.68 57.0 5.87e-01 98.1% 98.0%
3288971 101.1.1.30 ↗ alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 0.67 52.0 3.87e-01 96.2% 31.3%
3807993 5076.1.1.1 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.67 59.0 3.74e-01 100.0% 38.5%
4886009 3435.1.1.1 ↗ a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC › RdgC 0.67 47.0 2.95e-01 81.1% 13.3%
3327321 3843.1.1.0 ↗ alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K 0.65 56.0 4.66e-01 94.3% 77.8%
3214018 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.65 52.0 4.19e-01 84.9% 51.6%
3531209 105.1.1.1 ↗ alpha duplicates or obligate multimers › HLH-like › HLH, helix-loop-helix DNA-binding domain › HLH, helix-loop-helix DNA-binding domain › HLH 0.64 52.0 4.83e-01 100.0% 71.4%
4562263 3435.1.1.1 ↗ a+b two layers › Recombination-associated protein rdgC › Recombination-associated protein rdgC › Recombination-associated protein rdgC › RdgC 0.64 46.0 2.90e-01 79.2% 13.5%
5083838 3896.1.1.0 ↗ alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase 0.64 48.0 3.19e-01 83.0% 19.7%
4663875 142.1.1.0 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.64 53.0 3.43e-01 94.3% 20.4%
3259657 605.8.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › BAS1536-like › BAS1536-like 0.64 52.0 4.75e-01 90.6% 77.1%
3284461 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.63 52.0 3.40e-01 96.2% 22.8%
5039745 2003.1.1.36 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 3HCDH_N 0.61 42.0 2.86e-01 84.9% 17.8%
3188736 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.59 45.0 3.06e-01 83.0% 24.0%
3926645 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.59 49.0 4.15e-01 90.6% 77.6%
3170253 632.3.1.11 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Phosphoprotein XD domain › Phosphoprotein XD domain › SUV3_C 0.58 49.0 4.36e-01 92.5% 66.7%
3462217 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.57 49.0 4.16e-01 98.1% 65.6%
4084484 6155.1.1.17 ↗ alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › LAB_N 0.53 43.0 3.91e-01 94.3% 85.3%