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P4a_precursor

Euk-Vir

Raccoonpox_virus

P4a_precursor__YP_009143437__Raccoonpox_virus__10256

Identity

Accession:
YP_009143437 ↗
Protein ID:
P4a_precursor
Kingdom:
euk

Quality

75.9 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Raccoonpox_virus

TaxID: 10256

Cluster

View cluster (29 members)

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 11-34_436-461_630-701
PDB
D2 medium residues 35-180_364-377
PDB
Domain cluster: rep: 101L_protein__NP_073486__Yaba-like_disease_virus__132475__D42-179
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03395.20 best Pox_P4A 182.5 1.30e-53 97.5% 16.5%
D3 medium residues 181-245
PDB
Domain cluster: rep: core_wall_protein__YP_005296306__Cotia_virus_SPAn232__930275__D180-247
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03395.20 best Pox_P4A 47.7 7.40e-13 100.0% 6.9%
D4 medium residues 246-363
PDB
Domain cluster: rep: P4a_precursor__YP_010085236__Western_grey_kangaroopox_virus__1566307__D246-346
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03395.20 best Pox_P4A 100.0 1.20e-28 100.0% 13.3%
D5 medium residues 378-435
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03395.20 best Pox_P4A 107.1 8.00e-31 100.0% 6.6%
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5ee2A00 2.40.160.90 Mainly Beta › Beta Barrel › Porin › 0.66 46.0 3.64e-01 74.1% 86.1%
4zohB02 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.66 52.0 4.30e-01 89.7% 87.2%
2eixA01 2.40.30.10 Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › Translation factors 0.62 50.0 4.16e-01 91.4% 87.7%
4pytA02 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.61 49.0 3.91e-01 93.1% 73.4%
5escA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.61 47.0 3.79e-01 86.2% 58.8%
3v10A02 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.60 49.0 3.72e-01 93.1% 69.9%
2vfrA02 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.60 47.0 3.76e-01 91.4% 72.3%
2mc2A00 2.80.10.50 Mainly Beta › Trefoil › Trefoil (Acidic Fibroblast Growth Factor, subunit A) › 0.60 40.0 2.80e-01 70.7% 98.1%
2htdB00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.59 47.0 3.82e-01 93.1% 60.5%
3tg9A00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.59 41.0 2.65e-01 75.9% 94.1%
4ybnB00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.58 47.0 3.36e-01 96.6% 97.6%
6iikB00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.58 47.0 3.04e-01 96.6% 53.9%
3loiA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.58 46.0 3.46e-01 91.4% 65.0%
2q9kA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.58 46.0 3.59e-01 94.8% 84.4%
1w1oA02 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.58 45.0 3.60e-01 89.7% 75.6%
1zr6A02 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.57 46.0 3.58e-01 93.1% 82.3%
1n6uA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 45.0 3.84e-01 93.1% 73.6%
1e0yA02 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.57 44.0 3.72e-01 91.4% 84.7%
6l4cA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.57 44.0 3.18e-01 87.9% 52.2%
1vhvA02 3.30.950.10 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain 0.57 44.0 3.50e-01 91.4% 68.3%
2jxtA01 3.10.20.10 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.56 39.0 3.66e-01 75.9% 78.9%
2e0nB02 3.30.950.10 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain 0.56 45.0 3.75e-01 94.8% 71.4%
2ol5A00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.55 43.0 3.14e-01 89.7% 94.0%
4yarA02 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.55 43.0 3.51e-01 89.7% 68.3%
1wfjA01 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.55 42.0 3.36e-01 84.5% 50.8%
1zq1A01 2.30.30.520 Mainly Beta › Roll › SH3 type barrels. › 0.55 43.0 4.05e-01 91.4% 90.9%
3hsuA01 3.30.465.10 Alpha Beta › 2-Layer Sandwich › Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase; domain 3 › 0.55 43.0 2.97e-01 93.1% 27.6%
4d0qA00 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.54 45.0 3.37e-01 96.6% 87.6%
5exvC00 3.40.1570.10 Alpha Beta › 3-Layer(aba) Sandwich › Heme iron utilization protein-like fold › HemS/ChuS/ChuX like domains 0.54 43.0 3.21e-01 91.4% 64.2%
1dq3A01 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.54 41.0 2.96e-01 84.5% 96.6%
4d8mA02 2.60.120.260 Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like 0.54 44.0 3.31e-01 100.0% 95.3%
2yrbA01 2.60.40.150 Mainly Beta › Sandwich › Immunoglobulin-like › C2 domain 0.53 41.0 3.28e-01 89.7% 55.6%
6kbyA00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.53 38.0 2.43e-01 79.3% 89.5%
2oviA00 3.40.1570.10 Alpha Beta › 3-Layer(aba) Sandwich › Heme iron utilization protein-like fold › HemS/ChuS/ChuX like domains 0.53 41.0 3.18e-01 91.4% 67.7%
5o9iA00 2.170.16.10 Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain 0.53 39.0 2.89e-01 82.8% 98.8%
1m4jA00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.53 35.0 2.79e-01 98.3% 30.1%
1ff9A02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.52 38.0 2.86e-01 86.2% 40.4%
1zcdA00 1.20.1530.10 Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › Na+/H+ antiporter like domain 0.51 37.0 2.35e-01 82.8% 91.0%
2htiA00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.51 38.0 3.17e-01 89.7% 54.8%
4r7rA00 3.30.1490.410 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Uncharacterised protein PF16224, DUF4883 0.51 37.0 3.07e-01 84.5% 55.7%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4544363 7513.1.1.1 ↗ a/b three-layered sandwiches › CofD-like › CofD-like › CofD-like › CofD 0.71 54.0 3.39e-01 82.8% 56.1%
4928815 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.70 57.0 5.50e-01 87.9% 89.2%
3572941 1.1.7.7 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 0.61 51.0 4.30e-01 96.6% 90.5%
4880118 2.4.1.1 ↗ beta barrels › OB-fold › MOP-like › MOP-like › TOBE 0.61 37.0 3.46e-01 79.3% 50.0%
4989335 1137.1.1.1 ↗ a+b two layers › Tetrapyrrole methylase C-terminal domain-like › Tetrapyrrole methylase C-terminal domain › Tetrapyrrole methylase C-terminal domain › TP_methylase 0.61 48.0 4.09e-01 89.7% 79.0%
3534443 221.1.1.12 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › RBD 0.60 50.0 4.42e-01 93.1% 89.4%
4944194 217.1.1.1 ↗ a+b complex topology › FAD-binding domain-like › FAD-binding domain › FAD-binding domain › FAD_binding_5 0.59 48.0 3.51e-01 94.8% 34.4%
3748643 221.1.1.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.59 49.0 4.42e-01 93.1% 95.0%
3597730 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.59 48.0 3.41e-01 94.8% 56.5%
3744808 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.59 46.0 3.35e-01 91.4% 53.5%
None — 0.59 45.0 3.29e-01 84.5% 93.3%
3288278 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.59 46.0 3.63e-01 89.7% 51.1%
4156798 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.58 41.0 3.15e-01 77.6% 97.2%
3776602 7590.1.1.7 ↗ a/b three-layered sandwiches › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › Middle domain in Argonaute homologs › MID_MedPIWI 0.57 41.0 2.64e-01 75.9% 95.8%
3787756 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.57 45.0 3.41e-01 91.4% 48.1%
4944685 1.1.5.18 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › FMN_bind_2 0.57 42.0 3.26e-01 84.5% 46.0%
4000496 6171.1.1.0 ↗ alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases 0.57 43.0 3.06e-01 86.2% 84.0%
3609901 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.56 44.0 3.26e-01 87.9% 48.8%
4947401 1.1.5.0 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel 0.56 43.0 3.27e-01 87.9% 73.5%
4997723 1.1.5.31 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Pyridox_ox_2 0.55 41.0 3.15e-01 86.2% 45.2%
4642857 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.55 42.0 3.89e-01 87.9% 98.8%
4514555 1.1.5.18 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › FMN_bind_2 0.54 42.0 3.06e-01 91.4% 92.8%
4019128 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.54 44.0 3.19e-01 96.6% 44.7%
2496895 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.54 42.0 3.66e-01 89.7% 71.1%
3415385 11.2.1.31 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › DUF4788 0.54 41.0 3.24e-01 86.2% 51.1%
4335507 221.1.5.1 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Chemotaxis inhibitory protein CHIPS › CHIPS 0.53 43.0 3.67e-01 94.8% 59.0%
3848399 4.8.1.24 ↗ beta barrels › SH3 › Chromo domain-like › Chromo domain-like › Chromo_MORC2_6th 0.53 38.0 3.68e-01 79.3% 97.1%
3519254 6171.1.1.0 ↗ alpha bundles › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases › C-terminal helical domain in Jumonji domain-containing histone demethylases 0.53 40.0 2.93e-01 84.5% 87.8%
4400460 1.1.5.8 ↗ beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Putative_PNPOx 0.52 43.0 3.37e-01 96.6% 50.7%
3594316 245.1.1.1 ↗ a+b two layers › Ribonuclease PH domain 2-like › Ribonuclease PH domain 2 › Ribonuclease PH domain 2 › RNase_PH_C 0.52 35.0 3.23e-01 70.7% 95.3%
3222807 10.32.1.0 ↗ beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.52 42.0 3.46e-01 93.1% 85.2%
4000080 11.2.1.1 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › C2 0.51 40.0 3.10e-01 89.7% 44.1%
4025560 245.1.1.0 ↗ a+b two layers › Ribonuclease PH domain 2-like › Ribonuclease PH domain 2 › Ribonuclease PH domain 2 0.51 37.0 3.20e-01 77.6% 83.2%
3965555 10.12.1.40 ↗ beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › JmjC_2 0.51 39.0 2.61e-01 89.7% 53.7%
3870120 1181.1.1.0 ↗ 0.51 37.0 3.47e-01 81.0% 82.7%
5065071 210.1.3.5 ↗ a+b four layers › Ntn/PP2C › Ntn › Class II glutamine amidotransferases › GATase_7 0.50 41.0 2.88e-01 94.8% 30.5%
3273590 11.2.1.0 ↗ beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain 0.50 37.0 2.88e-01 89.7% 43.5%
3799904 4.1.1.315 ↗ beta barrels › SH3 › SH3 › SH3 › SH3_12, XRN1_D1 0.50 38.0 2.39e-01 89.7% 40.0%
D6 medium residues 462-537
PDB
Domain cluster: rep: P4a_precursor__YP_010085400__Eastern_grey_kangaroopox_virus__2042482__D462-532_561-583
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03395.20 best Pox_P4A 135.6 1.90e-39 100.0% 8.4%