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P4a_precursor
Euk-VirWestern_grey_kangaroopox_virus
P4a_precursor__YP_010085236__Western_grey_kangaroopox_virus__1566307
Identity
- Accession:
- YP_010085236 ↗
- Protein ID:
- P4a_precursor
- Kingdom:
- euk
Quality
70.3
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Macropopoxvirus›
Western_grey_kangaroopox_virus
TaxID: 1566307
Cluster
View cluster (29 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 441-455_633-705
D2
medium
residues 37-168_363-435
Domain cluster:
representative
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03395.20 best | Pox_P4A | 131.4 | 3.60e-38 | 65.8% | 14.7% |
| PF03395.20 | Pox_P4A | 123.0 | 1.30e-35 | 35.6% | 8.0% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2a07J00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 23.0 | 3.36e-01 | 93.2% | 97.6% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3257775 | 4988.1.1.0 ↗ | a+b two layers › Ribosomal protein S8, C-terminal domain › Ribosomal protein S8, C-terminal domain › Ribosomal protein S8, C-terminal domain | 0.60 | 21.0 | 3.70e-01 | 95.1% | 100.0% |
| 3718390 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.58 | 22.0 | 3.63e-01 | 96.1% | 94.7% |
D3
medium
residues 246-346
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03395.20 best | Pox_P4A | 84.5 | 5.60e-24 | 100.0% | 11.5% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3ossC00 | 2.30.30.830 | Mainly Beta › Roll › SH3 type barrels. › | 0.57 | 28.0 | 3.42e-01 | 84.2% | 72.3% |
| 3p8aA02 | 2.60.40.4320 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.52 | 28.0 | 2.96e-01 | 79.2% | 55.6% |
| 2ci8A01 | 3.30.505.10 | Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain | 0.51 | 27.0 | 3.36e-01 | 76.2% | 89.3% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3244960 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.61 | 27.0 | 3.06e-01 | 71.3% | 53.3% |
| 3976834 | 4.1.1.156 ↗ | beta barrels › SH3 › SH3 › SH3 › DUF2158 | 0.56 | 24.0 | 3.31e-01 | 86.1% | 78.0% |
| 3335386 | 2003.1.2.15 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 | 0.52 | 36.0 | 2.47e-01 | 70.3% | 96.4% |
| 3684646 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.52 | 29.0 | 3.19e-01 | 81.2% | 66.3% |
D4
medium
residues 457-509
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03395.20 best | Pox_P4A | 80.2 | 1.10e-22 | 100.0% | 6.0% |
CATH (19)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.81 | 58.0 | 4.58e-01 | 75.5% | 68.6% |
| 2hxiB02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.67 | 53.0 | 3.98e-01 | 86.8% | 98.5% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 46.0 | 3.74e-01 | 75.5% | 57.8% |
| 4m70B00 | 1.10.246.200 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain | 0.64 | 49.0 | 4.20e-01 | 88.7% | 84.6% |
| 7og5F01 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.62 | 44.0 | 3.28e-01 | 77.4% | 26.8% |
| 3s6jE02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.62 | 48.0 | 4.39e-01 | 83.0% | 100.0% |
| 6qv3A05 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.61 | 42.0 | 3.49e-01 | 71.7% | 83.9% |
| 5lnkA00 | 1.20.58.1610 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 | 0.61 | 44.0 | 3.46e-01 | 75.5% | 40.0% |
| 7jv7B01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.60 | 45.0 | 3.42e-01 | 84.9% | 34.9% |
| 1ffyA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.58 | 47.0 | 2.82e-01 | 90.6% | 13.8% |
| 7b9cA02 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.58 | 39.0 | 2.43e-01 | 73.6% | 10.6% |
| 2yi9A02 | 1.10.287.540 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.57 | 39.0 | 3.98e-01 | 71.7% | 80.8% |
| 3g36B00 | 1.20.890.10 | Mainly Alpha › Up-down Bundle › cAMP-dependent Protein Kinase, Chain A › cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain | 0.57 | 44.0 | 4.51e-01 | 92.5% | 90.2% |
| 1b72A00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.57 | 40.0 | 3.77e-01 | 92.5% | 60.3% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.54 | 43.0 | 3.11e-01 | 86.8% | 40.1% |
| 1nt2B02 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.53 | 37.0 | 3.48e-01 | 73.6% | 58.2% |
| 8b6jF01 | 1.10.287.20 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain | 0.51 | 41.0 | 3.84e-01 | 90.6% | 76.1% |
| 1vwxQ00 | 3.100.10.10 | Alpha Beta › Ribosomal Protein L15; Chain: K; domain 2 › Ribosomal Protein L15; Chain: K; domain 2 › | 0.51 | 40.0 | 2.88e-01 | 94.3% | 27.8% |
| 1vg5A00 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.50 | 33.0 | 3.03e-01 | 81.1% | 49.3% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3361803 | 632.3.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Phosphoprotein XD domain › Phosphoprotein XD domain | 0.83 | 60.0 | 6.19e-01 | 77.4% | 88.0% |
| 4092193 | 3755.4.1.53 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › CemA | 0.78 | 57.0 | 4.06e-01 | 79.2% | 40.6% |
| 4012233 | 4957.1.1.0 ↗ | a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit | 0.76 | 59.0 | 3.88e-01 | 84.9% | 40.5% |
| 3700717 | 70.3.1.1 ↗ | beta barrels › beta-clip › SET domain-like › SET domain-like › SET | 0.71 | 50.0 | 3.24e-01 | 73.6% | 65.8% |
| 3716257 | 1189.1.1.0 ↗ | alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor | 0.67 | 51.0 | 3.82e-01 | 83.0% | 82.2% |
| 4028664 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.65 | 46.0 | 3.83e-01 | 75.5% | 53.7% |
| 4569675 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.65 | 50.0 | 4.01e-01 | 83.0% | 43.8% |
| 3516645 | 301.6.1.1 ↗ | a+b three layers › Bacillus chorismate mutase-like › Tubulin C-terminal domain-like › Tubulin C-terminal domain-like › Tubulin_C | 0.65 | 44.0 | 2.96e-01 | 71.7% | 34.0% |
| 3492889 | 11.2.1.19 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › DUF3657 | 0.65 | 51.0 | 3.24e-01 | 90.6% | 56.1% |
| 5007660 | 101.1.1.187 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_33 | 0.64 | 47.0 | 4.50e-01 | 92.5% | 67.7% |
| 4937380 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.63 | 49.0 | 4.39e-01 | 84.9% | 89.3% |
| 3583210 | 5.1.2.2 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › WD40 | 0.63 | 54.0 | 3.81e-01 | 100.0% | 99.4% |
| 3732977 | 2486.1.1.3 ↗ | a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › Carboxyl_trans | 0.63 | 49.0 | 2.83e-01 | 86.8% | 36.1% |
| 3416533 | 614.1.1.0 ↗ | alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain | 0.62 | 44.0 | 4.31e-01 | 77.4% | 75.0% |
| 3232180 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 42.0 | 2.76e-01 | 71.7% | 35.1% |
| 3619616 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.61 | 44.0 | 3.83e-01 | 77.4% | 72.9% |
| 3484360 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.60 | 46.0 | 4.28e-01 | 84.9% | 71.4% |
| 3480389 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.60 | 42.0 | 3.76e-01 | 75.5% | 52.5% |
| 3246596 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.60 | 40.0 | 3.70e-01 | 83.0% | 50.7% |
| 3244955 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.60 | 40.0 | 3.83e-01 | 73.6% | 56.9% |
| 3874841 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.59 | 40.0 | 3.84e-01 | 83.0% | 58.5% |
| 3967936 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.59 | 46.0 | 4.18e-01 | 86.8% | 77.3% |
| 3783785 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.59 | 40.0 | 3.71e-01 | 81.1% | 54.3% |
| 3933062 | 622.1.1.14 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › Proton_antipo_M | 0.59 | 42.0 | 3.79e-01 | 75.5% | 54.7% |
| 3278143 | 1075.3.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold | 0.58 | 48.0 | 3.04e-01 | 98.1% | 95.5% |
| 3686904 | 2486.1.1.3 ↗ | a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › Carboxyl_trans | 0.58 | 42.0 | 2.91e-01 | 79.2% | 22.1% |
| 3228638 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.58 | 46.0 | 2.85e-01 | 94.3% | 32.5% |
| 4024078 | 3981.1.1.4 ↗ | alpha bundles › Mitochondrial distribution and morphology protein 35 › Mitochondrial distribution and morphology protein 35 › Mitochondrial distribution and morphology protein 35 › COX6B | 0.56 | 42.0 | 3.99e-01 | 88.7% | 72.9% |
| 3478184 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.56 | 38.0 | 3.22e-01 | 83.0% | 39.0% |
| 3751844 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.55 | 39.0 | 3.38e-01 | 88.7% | 44.2% |
| 3933833 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.55 | 39.0 | 3.61e-01 | 83.0% | 55.7% |
| 3484058 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.53 | 37.0 | 3.29e-01 | 84.9% | 47.1% |
| 4282585 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.53 | 40.0 | 3.57e-01 | 90.6% | 57.6% |
| 3886591 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.51 | 39.0 | 3.56e-01 | 90.6% | 67.5% |
| 3894143 | 101.1.1.1 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain | 0.51 | 39.0 | 3.53e-01 | 90.6% | 66.3% |
D5
medium
residues 510-601_619-630
Domain cluster:
rep: P4a_precursor__YP_009480637__Sea_otter_poxvirus__1416741__D521-601_638-649
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03395.20 best | Pox_P4A | 141.6 | 3.10e-41 | 97.1% | 10.1% |
D6
medium
residues 718-881