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P4a_precursor

Euk-Vir

Western_grey_kangaroopox_virus

P4a_precursor__YP_010085236__Western_grey_kangaroopox_virus__1566307

Identity

Accession:
YP_010085236 ↗
Protein ID:
P4a_precursor
Kingdom:
euk

Quality

70.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 441-455_633-705
PDB
D2 medium residues 37-168_363-435
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF03395.20 best Pox_P4A 131.4 3.60e-38 65.8% 14.7%
PF03395.20 Pox_P4A 123.0 1.30e-35 35.6% 8.0%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2a07J00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.51 23.0 3.36e-01 93.2% 97.6%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3257775 4988.1.1.0 a+b two layers › Ribosomal protein S8, C-terminal domain › Ribosomal protein S8, C-terminal domain › Ribosomal protein S8, C-terminal domain 0.60 21.0 3.70e-01 95.1% 100.0%
3718390 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.58 22.0 3.63e-01 96.1% 94.7%
D3 medium residues 246-346
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03395.20 best Pox_P4A 84.5 5.60e-24 100.0% 11.5%
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ossC00 2.30.30.830 Mainly Beta › Roll › SH3 type barrels. › 0.57 28.0 3.42e-01 84.2% 72.3%
3p8aA02 2.60.40.4320 Mainly Beta › Sandwich › Immunoglobulin-like › 0.52 28.0 2.96e-01 79.2% 55.6%
2ci8A01 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.51 27.0 3.36e-01 76.2% 89.3%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3244960 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.61 27.0 3.06e-01 71.3% 53.3%
3976834 4.1.1.156 beta barrels › SH3 › SH3 › SH3 › DUF2158 0.56 24.0 3.31e-01 86.1% 78.0%
3335386 2003.1.2.15 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FAD_binding_3 0.52 36.0 2.47e-01 70.3% 96.4%
3684646 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.52 29.0 3.19e-01 81.2% 66.3%
D4 medium residues 457-509
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03395.20 best Pox_P4A 80.2 1.10e-22 100.0% 6.0%
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.81 58.0 4.58e-01 75.5% 68.6%
2hxiB02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.67 53.0 3.98e-01 86.8% 98.5%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.65 46.0 3.74e-01 75.5% 57.8%
4m70B00 1.10.246.200 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain 0.64 49.0 4.20e-01 88.7% 84.6%
7og5F01 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.62 44.0 3.28e-01 77.4% 26.8%
3s6jE02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.62 48.0 4.39e-01 83.0% 100.0%
6qv3A05 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 42.0 3.49e-01 71.7% 83.9%
5lnkA00 1.20.58.1610 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 0.61 44.0 3.46e-01 75.5% 40.0%
7jv7B01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.60 45.0 3.42e-01 84.9% 34.9%
1ffyA01 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.58 47.0 2.82e-01 90.6% 13.8%
7b9cA02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.58 39.0 2.43e-01 73.6% 10.6%
2yi9A02 1.10.287.540 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.57 39.0 3.98e-01 71.7% 80.8%
3g36B00 1.20.890.10 Mainly Alpha › Up-down Bundle › cAMP-dependent Protein Kinase, Chain A › cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain 0.57 44.0 4.51e-01 92.5% 90.2%
1b72A00 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.57 40.0 3.77e-01 92.5% 60.3%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.54 43.0 3.11e-01 86.8% 40.1%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.53 37.0 3.48e-01 73.6% 58.2%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.51 41.0 3.84e-01 90.6% 76.1%
1vwxQ00 3.100.10.10 Alpha Beta › Ribosomal Protein L15; Chain: K; domain 2 › Ribosomal Protein L15; Chain: K; domain 2 › 0.51 40.0 2.88e-01 94.3% 27.8%
1vg5A00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.50 33.0 3.03e-01 81.1% 49.3%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3361803 632.3.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Phosphoprotein XD domain › Phosphoprotein XD domain 0.83 60.0 6.19e-01 77.4% 88.0%
4092193 3755.4.1.53 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › CemA 0.78 57.0 4.06e-01 79.2% 40.6%
4012233 4957.1.1.0 a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit 0.76 59.0 3.88e-01 84.9% 40.5%
3700717 70.3.1.1 beta barrels › beta-clip › SET domain-like › SET domain-like › SET 0.71 50.0 3.24e-01 73.6% 65.8%
3716257 1189.1.1.0 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.67 51.0 3.82e-01 83.0% 82.2%
4028664 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.65 46.0 3.83e-01 75.5% 53.7%
4569675 101.11.1.1 alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.65 50.0 4.01e-01 83.0% 43.8%
3516645 301.6.1.1 a+b three layers › Bacillus chorismate mutase-like › Tubulin C-terminal domain-like › Tubulin C-terminal domain-like › Tubulin_C 0.65 44.0 2.96e-01 71.7% 34.0%
3492889 11.2.1.19 beta sandwiches › Immunoglobulin-like beta-sandwich › C2 domain › C2 domain › DUF3657 0.65 51.0 3.24e-01 90.6% 56.1%
5007660 101.1.1.187 alpha arrays › HTH › HTH › Three-helical HTH › HTH_33 0.64 47.0 4.50e-01 92.5% 67.7%
4937380 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.63 49.0 4.39e-01 84.9% 89.3%
3583210 5.1.2.2 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › WD40 0.63 54.0 3.81e-01 100.0% 99.4%
3732977 2486.1.1.3 a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › Carboxyl_trans 0.63 49.0 2.83e-01 86.8% 36.1%
3416533 614.1.1.0 alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain 0.62 44.0 4.31e-01 77.4% 75.0%
3232180 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 42.0 2.76e-01 71.7% 35.1%
3619616 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.61 44.0 3.83e-01 77.4% 72.9%
3484360 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.60 46.0 4.28e-01 84.9% 71.4%
3480389 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.60 42.0 3.76e-01 75.5% 52.5%
3246596 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.60 40.0 3.70e-01 83.0% 50.7%
3244955 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.60 40.0 3.83e-01 73.6% 56.9%
3874841 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.59 40.0 3.84e-01 83.0% 58.5%
3967936 142.1.1.3 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 0.59 46.0 4.18e-01 86.8% 77.3%
3783785 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.59 40.0 3.71e-01 81.1% 54.3%
3933062 622.1.1.14 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › Proton_antipo_M 0.59 42.0 3.79e-01 75.5% 54.7%
3278143 1075.3.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold 0.58 48.0 3.04e-01 98.1% 95.5%
3686904 2486.1.1.3 a/b three-layered sandwiches › ClpP/crotonase › ClpP/crotonase › ClpP/crotonase › Carboxyl_trans 0.58 42.0 2.91e-01 79.2% 22.1%
3228638 5001.1.1.41 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw 0.58 46.0 2.85e-01 94.3% 32.5%
4024078 3981.1.1.4 alpha bundles › Mitochondrial distribution and morphology protein 35 › Mitochondrial distribution and morphology protein 35 › Mitochondrial distribution and morphology protein 35 › COX6B 0.56 42.0 3.99e-01 88.7% 72.9%
3478184 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.56 38.0 3.22e-01 83.0% 39.0%
3751844 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.55 39.0 3.38e-01 88.7% 44.2%
3933833 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.55 39.0 3.61e-01 83.0% 55.7%
3484058 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.53 37.0 3.29e-01 84.9% 47.1%
4282585 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.53 40.0 3.57e-01 90.6% 57.6%
3886591 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.51 39.0 3.56e-01 90.6% 67.5%
3894143 101.1.1.1 alpha arrays › HTH › HTH › Three-helical HTH › Homeodomain 0.51 39.0 3.53e-01 90.6% 66.3%
D5 medium residues 510-601_619-630
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF03395.20 best Pox_P4A 141.6 3.10e-41 97.1% 10.1%
D6 medium residues 718-881
PDB