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PH2015_18_scaffold_2_prodigal-single.1__X__X__00488
Bact-VirPH2015_18_scaffold_2_prodigal-single.1__X__X__00488
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 23-159
Domain cluster:
rep: IMGVR_UViG_3300013099_000017-3300013099-Ga0164315_10000001137__D1-116
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3pvuA02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.60 | 29.0 | 3.66e-01 | 75.9% | 76.2% |
| 1c9bA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.57 | 28.0 | 3.22e-01 | 73.0% | 62.9% |
| 4jbeB01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.53 | 40.0 | 3.26e-01 | 79.6% | 95.2% |
| 1f5qB01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.51 | 28.0 | 3.12e-01 | 72.3% | 66.1% |
D2
high
residues 170-289
Domain cluster:
rep: KF301602.1__AGS80890.1__X__00005__D135-234
CATH (30)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3d36B02 | 1.10.287.130 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain | 0.69 | 36.0 | 4.82e-01 | 96.7% | 98.4% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.67 | 42.0 | 4.85e-01 | 86.7% | 87.1% |
| 4mndA02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.67 | 39.0 | 3.33e-01 | 75.8% | 35.6% |
| 1j1jA02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.66 | 41.0 | 4.71e-01 | 86.7% | 85.9% |
| 4m0mA03 | 1.20.1270.430 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.65 | 28.0 | 3.47e-01 | 90.8% | 60.8% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.65 | 42.0 | 4.88e-01 | 81.7% | 94.0% |
| 2yevA03 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.61 | 46.0 | 3.99e-01 | 79.2% | 95.1% |
| 4k84A00 | 1.10.3520.10 | Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein | 0.61 | 51.0 | 4.26e-01 | 90.0% | 88.8% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.61 | 47.0 | 4.96e-01 | 87.5% | 89.1% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.61 | 36.0 | 4.29e-01 | 96.7% | 89.6% |
| 1t72A02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.60 | 43.0 | 4.74e-01 | 87.5% | 90.8% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 35.0 | 4.24e-01 | 85.8% | 94.5% |
| 1q6aA00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.58 | 44.0 | 4.62e-01 | 100.0% | 90.7% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 44.0 | 4.38e-01 | 83.3% | 76.2% |
| 1aluA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.55 | 45.0 | 4.07e-01 | 85.0% | 78.3% |
| 2wy4A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 43.0 | 4.15e-01 | 98.3% | 72.7% |
| 1kplA00 | 1.10.3080.10 | Mainly Alpha › Orthogonal Bundle › Clc chloride channel › Clc chloride channel | 0.55 | 38.0 | 2.70e-01 | 72.5% | 90.0% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.54 | 35.0 | 4.08e-01 | 82.5% | 97.5% |
| 4c0eA01 | 1.25.40.790 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 43.0 | 3.32e-01 | 99.2% | 36.7% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.54 | 47.0 | 4.28e-01 | 96.7% | 93.9% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 41.0 | 3.98e-01 | 86.7% | 72.1% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.53 | 43.0 | 4.45e-01 | 85.8% | 91.2% |
| 2o57A01 | 1.10.287.840 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mycolic acid cyclopropane synthase domain like | 0.52 | 39.0 | 4.19e-01 | 77.5% | 89.5% |
| 4f0cA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 35.0 | 3.37e-01 | 80.8% | 58.7% |
| 2x6hA03 | 1.10.1070.11 | Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain | 0.52 | 45.0 | 3.84e-01 | 96.7% | 81.0% |
| 4dloB02 | 1.25.40.610 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 40.0 | 4.07e-01 | 93.3% | 85.5% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.52 | 40.0 | 4.10e-01 | 81.7% | 93.8% |
| 3lsjA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 44.0 | 4.13e-01 | 99.2% | 76.5% |
| 1abvA00 | 1.10.520.20 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.51 | 38.0 | 4.01e-01 | 78.3% | 98.1% |
| 4pdyA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.50 | 45.0 | 3.66e-01 | 100.0% | 57.9% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4929003 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.67 | 43.0 | 4.93e-01 | 81.7% | 86.7% |
| 4316383 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.66 | 40.0 | 4.43e-01 | 96.7% | 75.8% |
| 3477822 | 1147.1.1.1 ↗ | alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL | 0.64 | 49.0 | 4.87e-01 | 79.2% | 93.6% |
| 3270860 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.63 | 40.0 | 3.64e-01 | 99.2% | 49.0% |
| 3887481 | 192.13.1.0 ↗ | alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like | 0.63 | 50.0 | 5.30e-01 | 98.3% | 94.3% |
| 3256571 | 6155.1.1.1 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv | 0.63 | 42.0 | 4.64e-01 | 81.7% | 85.3% |
| 3236773 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.60 | 50.0 | 4.84e-01 | 88.3% | 90.4% |
| 3434384 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 46.0 | 3.99e-01 | 100.0% | 52.4% |
| 3669425 | 109.4.1.541 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF4220 | 0.60 | 47.0 | 3.67e-01 | 82.5% | 97.6% |
| 4007380 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.60 | 48.0 | 3.97e-01 | 84.2% | 73.7% |
| 3958339 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.60 | 36.0 | 3.60e-01 | 70.0% | 56.8% |
| 4015560 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.58 | 51.0 | 3.95e-01 | 95.8% | 84.5% |
| 4476660 | 192.8.1.478 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › BAG6 | 0.58 | 41.0 | 4.12e-01 | 91.7% | 70.4% |
| 3577574 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.58 | 47.0 | 4.19e-01 | 90.0% | 87.8% |
| 3496002 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.57 | 47.0 | 4.42e-01 | 87.5% | 83.2% |
| 3417726 | 604.1.1.116 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SCAMP | 0.57 | 47.0 | 4.13e-01 | 89.2% | 86.9% |
| 3865100 | 109.4.1.368 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SHNi-TPR | 0.56 | 43.0 | 3.18e-01 | 95.0% | 32.2% |
| 3660496 | 604.3.1.19 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › DUF3475 | 0.56 | 42.0 | 3.48e-01 | 80.0% | 60.9% |
| 3908126 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.56 | 47.0 | 4.48e-01 | 90.0% | 87.9% |
| 4150398 | 633.23.1.32 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › CASP_dom | 0.56 | 46.0 | 4.17e-01 | 88.3% | 85.6% |
| 3321236 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.55 | 47.0 | 3.98e-01 | 90.8% | 93.7% |
| 3517330 | 603.2.1.1 ↗ | alpha bundles › STAT-like › STAT › STAT › STAT_alpha | 0.55 | 48.0 | 3.96e-01 | 94.2% | 92.9% |
| 2722116 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.55 | 46.0 | 3.90e-01 | 90.0% | 81.9% |
| 3814336 | 603.2.1.13 ↗ | alpha bundles › STAT-like › STAT › STAT › NET2A_C | 0.54 | 43.0 | 3.99e-01 | 85.0% | 83.2% |
| 3673003 | 3922.1.1.254 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › NET2A_C | 0.54 | 44.0 | 4.41e-01 | 87.5% | 84.0% |
| 3277002 | 3252.1.1.0 ↗ | alpha arrays › SHQ1 C-terminal domain-like › SHQ1 C-terminal domain › SHQ1 C-terminal domain | 0.53 | 49.0 | 3.85e-01 | 100.0% | 88.2% |
| 3282251 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.53 | 40.0 | 3.97e-01 | 80.0% | 84.5% |
| 3983403 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.53 | 42.0 | 3.63e-01 | 84.2% | 80.0% |
| 3504301 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 40.0 | 4.18e-01 | 85.0% | 87.3% |
| 3804522 | 1147.1.1.1 ↗ | alpha bundles › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › RNA polymerase II elongation factor ELL2 C-terminal domain › Occludin_ELL | 0.52 | 41.0 | 4.18e-01 | 85.0% | 93.3% |
| 5072346 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.52 | 45.0 | 3.83e-01 | 94.2% | 73.5% |
| 3505434 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.52 | 41.0 | 4.10e-01 | 84.2% | 83.2% |
| 3237916 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.52 | 42.0 | 3.73e-01 | 88.3% | 78.2% |
| 3676390 | 3559.1.1.0 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 | 0.52 | 43.0 | 4.35e-01 | 87.5% | 87.5% |
| 4943005 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.52 | 43.0 | 3.58e-01 | 88.3% | 66.0% |
D3
high
residues 302-418
Domain cluster:
representative
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4c92G00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.71 | 42.0 | 5.07e-01 | 97.4% | 92.0% |
| 4f7uG00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.69 | 40.0 | 4.94e-01 | 99.1% | 97.1% |
| 4f7uF00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.69 | 41.0 | 4.97e-01 | 83.8% | 94.5% |
| 1d3bC00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.69 | 41.0 | 5.03e-01 | 98.3% | 97.2% |
| 1ljoA00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.68 | 40.0 | 4.82e-01 | 82.9% | 92.0% |
| 4c92F00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.65 | 41.0 | 4.88e-01 | 100.0% | 96.1% |
| 1b34B00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.65 | 38.0 | 4.65e-01 | 98.3% | 91.9% |
| 4c92C00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.63 | 41.0 | 4.79e-01 | 98.3% | 96.2% |
| 4c92B00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.61 | 38.0 | 4.02e-01 | 100.0% | 69.5% |
| 4bbwA02 | 2.120.10.10 | Mainly Beta › 6 Propeller › Neuraminidase › | 0.52 | 43.0 | 3.07e-01 | 90.6% | 86.1% |
| 6nobA01 | 2.115.10.20 | Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 | 0.51 | 39.0 | 2.75e-01 | 80.3% | 60.7% |
| 5fl4A00 | 3.10.200.10 | Alpha Beta › Roll › Carbonic Anhydrase II › Alpha carbonic anhydrase | 0.50 | 42.0 | 3.36e-01 | 93.2% | 93.6% |
| 1ri6A00 | 2.130.10.10 | Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase | 0.50 | 39.0 | 2.82e-01 | 82.9% | 48.0% |
ECOD (11)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 478 | 4.1.1.19 ↗ | beta barrels › SH3 › SH3 › SH3 › LSM | 0.68 | 40.0 | 4.82e-01 | 82.9% | 92.0% |
| 3277139 | 4.1.1.19 ↗ | beta barrels › SH3 › SH3 › SH3 › LSM | 0.66 | 43.0 | 4.38e-01 | 100.0% | 67.0% |
| 1489664 | 3933.1.1.1 ↗ | a+b two layers › Uncharacterized protein YPO2434 › Uncharacterized protein YPO2434 › Uncharacterized protein YPO2434 › KTSC | 0.66 | 40.0 | 4.90e-01 | 84.6% | 100.0% |
| 3626383 | 4.1.1.81 ↗ | beta barrels › SH3 › SH3 › SH3 › LSM14 | 0.64 | 40.0 | 4.36e-01 | 80.3% | 76.8% |
| 3786143 | 4.1.1.19 ↗ | beta barrels › SH3 › SH3 › SH3 › LSM | 0.63 | 40.0 | 4.26e-01 | 100.0% | 72.4% |
| 5060199 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.62 | 50.0 | 5.31e-01 | 100.0% | 96.2% |
| 3820621 | 4.1.1.81 ↗ | beta barrels › SH3 › SH3 › SH3 › LSM14 | 0.62 | 39.0 | 4.60e-01 | 80.3% | 92.5% |
| 3610074 | 4.1.1.81 ↗ | beta barrels › SH3 › SH3 › SH3 › LSM14 | 0.61 | 41.0 | 4.25e-01 | 100.0% | 71.8% |
| 4936711 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.53 | 37.0 | 3.99e-01 | 99.1% | 86.0% |
| 3790115 | 5.1.4.341 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_IFT140_2nd | 0.51 | 40.0 | 2.79e-01 | 83.8% | 50.3% |
| 3581100 | 5.1.3.170 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Beta-prop_IFT140_2nd | 0.51 | 40.0 | 3.19e-01 | 83.8% | 83.5% |