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PH2015_20_scaffold_1_prodigal-single.1__X__X__00139
Bact-VirPH2015_20_scaffold_1_prodigal-single.1__X__X__00139
Identity
- Kingdom:
- phage
Quality
57.7
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 107-183
D2
high
residues 193-282
Domain cluster:
representative
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3e99A00 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.64 | 38.0 | 3.25e-01 | 77.8% | 36.5% |
| 2obdA02 | 3.15.10.10 | Alpha Beta › Super Roll › Bactericidal permeability-increasing protein; domain 1 › Bactericidal permeability-increasing protein; domain 1 | 0.57 | 48.0 | 3.81e-01 | 93.3% | 56.6% |
| 3wlvA00 | 3.10.270.10 | Alpha Beta › Roll › Urate Oxidase › Urate Oxidase; | 0.55 | 42.0 | 2.95e-01 | 81.1% | 69.0% |
| 2qkdA01 | 2.20.25.420 | Mainly Beta › Single Sheet › N-terminal domain of TfIIb › ZPR1, zinc finger domain | 0.54 | 31.0 | 3.65e-01 | 84.4% | 97.9% |
| 2qrdA00 | 3.30.310.80 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 | 0.54 | 39.0 | 3.64e-01 | 85.6% | 60.5% |
| 7ly5B01 | 3.40.109.10 | Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase | 0.53 | 40.0 | 3.43e-01 | 82.2% | 69.9% |
| 1gkuB07 | 2.60.510.20 | Mainly Beta › Sandwich › EV matrix protein fold › | 0.53 | 32.0 | 3.11e-01 | 70.0% | 52.9% |
| 2je2A00 | 3.50.70.20 | Alpha Beta › 3-Layer(bba) Sandwich › Chalcone isomerase › Cytochrome P460 | 0.52 | 45.0 | 3.82e-01 | 98.9% | 98.7% |
| 5jenA01 | 3.30.565.40 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Fervidobacterium nodosum Rt17-B1 like | 0.52 | 27.0 | 2.53e-01 | 76.7% | 42.3% |
| 2gtlN02 | 2.40.128.620 | Mainly Beta › Beta Barrel › Lipocalin › | 0.51 | 43.0 | 3.52e-01 | 95.6% | 56.5% |
| 3cjeA00 | 3.30.300.20 | Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain | 0.50 | 38.0 | 3.24e-01 | 80.0% | 84.0% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3970009 | 243.1.1.0 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like | 0.63 | 40.0 | 3.26e-01 | 73.3% | 34.3% |
| 4283272 | 243.1.1.1 ↗ | a+b two layers › Cystatin-like › NTF2-like › NTF2-like › Ring_hydroxyl_B | 0.62 | 40.0 | 3.24e-01 | 73.3% | 34.1% |
| 5013525 | 5.1.2.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed | 0.57 | 38.0 | 3.46e-01 | 74.4% | 49.6% |
| 4464656 | 883.1.1.2 ↗ | a+b complex topology › Aha1/BPI domain-like › Aha1/BPI domain-like › Aha1/BPI domain-like › LBP_BPI_CETP_C | 0.55 | 48.0 | 3.50e-01 | 100.0% | 54.4% |
| 4592301 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.54 | 37.0 | 3.47e-01 | 97.8% | 56.5% |
| 3332026 | 331.3.1.28 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › DUF220 | 0.53 | 40.0 | 3.22e-01 | 82.2% | 68.4% |
| 3807674 | 331.3.1.28 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like › DUF220 | 0.53 | 41.0 | 3.07e-01 | 84.4% | 71.5% |
| 4632710 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.51 | 25.0 | 3.25e-01 | 92.2% | 88.9% |
D3
high
residues 670-809
Domain cluster:
representative
CATH (50)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 38.0 | 3.55e-01 | 100.0% | 40.5% |
| 1dn1B00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.71 | 45.0 | 3.84e-01 | 100.0% | 40.1% |
| 3rkgA02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.68 | 40.0 | 3.78e-01 | 100.0% | 50.0% |
| 3lmfA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.65 | 49.0 | 5.41e-01 | 84.3% | 100.0% |
| 1lkoA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 46.0 | 4.63e-01 | 100.0% | 74.5% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 57.0 | 4.59e-01 | 100.0% | 61.1% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 38.0 | 3.03e-01 | 100.0% | 32.5% |
| 3f7cA00 | 1.20.1590.10 | Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like | 0.60 | 41.0 | 3.71e-01 | 86.4% | 49.2% |
| 1qoyA00 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.60 | 52.0 | 4.11e-01 | 97.1% | 87.1% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 40.0 | 4.54e-01 | 72.9% | 90.7% |
| 1ylmA00 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.59 | 42.0 | 4.20e-01 | 72.1% | 79.6% |
| 7ae2A01 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.59 | 41.0 | 4.17e-01 | 70.7% | 78.8% |
| 2rgnB01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.58 | 52.0 | 4.62e-01 | 99.3% | 80.4% |
| 5h5mA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 40.0 | 4.13e-01 | 75.0% | 74.6% |
| 4gouA03 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.58 | 52.0 | 4.69e-01 | 100.0% | 86.8% |
| 7p3rA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.58 | 47.0 | 3.64e-01 | 88.6% | 94.8% |
| 5kdiA00 | 1.10.3520.10 | Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein | 0.58 | 49.0 | 4.31e-01 | 92.9% | 89.1% |
| 2xhsA00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.58 | 43.0 | 3.65e-01 | 79.3% | 94.2% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.57 | 47.0 | 4.56e-01 | 87.9% | 79.7% |
| 2b0hA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 39.0 | 4.10e-01 | 75.0% | 75.8% |
| 2l6hA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.57 | 38.0 | 3.77e-01 | 70.7% | 61.7% |
| 2qqyA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 44.0 | 4.47e-01 | 92.1% | 82.6% |
| 2aniA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.56 | 50.0 | 3.88e-01 | 98.6% | 74.1% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.56 | 43.0 | 4.29e-01 | 80.7% | 94.6% |
| 1bgcA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.56 | 44.0 | 4.31e-01 | 91.4% | 75.3% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 39.0 | 3.87e-01 | 83.6% | 65.6% |
| 3rvyA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.55 | 38.0 | 4.16e-01 | 86.4% | 90.7% |
| 2zopA00 | 1.10.520.30 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain | 0.55 | 33.0 | 3.60e-01 | 71.4% | 71.4% |
| 1urvA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.55 | 43.0 | 4.18e-01 | 83.6% | 95.5% |
| 2x0cA01 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.55 | 39.0 | 3.63e-01 | 73.6% | 98.3% |
| 2clbA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 43.0 | 4.12e-01 | 89.3% | 73.0% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.54 | 37.0 | 3.58e-01 | 74.3% | 60.8% |
| 1wwmA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.54 | 42.0 | 3.86e-01 | 86.4% | 62.2% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.54 | 35.0 | 3.80e-01 | 71.4% | 77.8% |
| 1x3kA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 41.0 | 4.12e-01 | 81.4% | 100.0% |
| 6k41R00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 38.0 | 3.23e-01 | 73.6% | 99.6% |
| 2lquA01 | 1.20.1420.40 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein | 0.53 | 38.0 | 3.71e-01 | 73.6% | 99.4% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.53 | 38.0 | 3.34e-01 | 75.7% | 51.2% |
| 6ko5A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 47.0 | 3.73e-01 | 99.3% | 66.4% |
| 2cfqA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 47.0 | 4.13e-01 | 100.0% | 91.0% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 45.0 | 4.25e-01 | 93.6% | 76.2% |
| 2nnwA02 | 1.10.287.4070 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 43.0 | 4.47e-01 | 100.0% | 98.4% |
| 2yw6B00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 43.0 | 4.24e-01 | 95.0% | 83.3% |
| 3ggyA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.52 | 45.0 | 4.11e-01 | 100.0% | 71.0% |
| 2v0pA00 | 1.25.40.540 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › TAP42-like family | 0.51 | 45.0 | 3.90e-01 | 95.0% | 61.5% |
| 6o0aA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 41.0 | 4.05e-01 | 86.4% | 98.7% |
| 1cpqA00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.51 | 35.0 | 3.65e-01 | 70.0% | 79.1% |
| 3cwzB01 | 1.20.58.900 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain | 0.51 | 37.0 | 3.66e-01 | 92.1% | 71.9% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 37.0 | 3.93e-01 | 77.1% | 88.9% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.50 | 35.0 | 2.92e-01 | 70.7% | 83.5% |
ECOD (54)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3970257 | 5069.1.1.5 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_II | 0.85 | 40.0 | 3.65e-01 | 100.0% | 36.1% |
| 3317539 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.71 | 32.0 | 3.52e-01 | 100.0% | 50.4% |
| 3398185 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 37.0 | 3.56e-01 | 100.0% | 46.9% |
| 3405706 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.64 | 56.0 | 5.78e-01 | 99.3% | 100.0% |
| 3613860 | 601.1.2.105 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Transmemb_17 | 0.64 | 56.0 | 5.65e-01 | 94.3% | 95.7% |
| 4024597 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.64 | 56.0 | 5.53e-01 | 95.0% | 88.7% |
| 3607681 | 633.10.1.15 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like › Transmemb_17 | 0.64 | 56.0 | 5.75e-01 | 95.7% | 99.3% |
| 3248267 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.63 | 56.0 | 5.54e-01 | 95.0% | 93.8% |
| 3895743 | 3615.1.1.7 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › CD20 | 0.63 | 57.0 | 5.16e-01 | 99.3% | 95.3% |
| 3917126 | 174.1.1.33 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Erg28 | 0.63 | 57.0 | 5.57e-01 | 99.3% | 100.0% |
| 3556701 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.62 | 56.0 | 5.46e-01 | 100.0% | 96.8% |
| 4546061 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.61 | 53.0 | 5.46e-01 | 96.4% | 100.0% |
| 3825046 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.60 | 55.0 | 5.44e-01 | 100.0% | 96.6% |
| 3226858 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.60 | 53.0 | 5.38e-01 | 96.4% | 100.0% |
| 5031295 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.59 | 41.0 | 4.17e-01 | 70.7% | 76.4% |
| 5079046 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.59 | 41.0 | 4.19e-01 | 70.7% | 79.9% |
| 3625558 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.59 | 51.0 | 5.24e-01 | 98.6% | 99.3% |
| 3913234 | 633.21.1.23 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › CD20 | 0.59 | 51.0 | 5.25e-01 | 99.3% | 100.0% |
| 5066783 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.59 | 52.0 | 5.00e-01 | 99.3% | 87.3% |
| 3209446 | 632.22.1.131 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › SOG2 | 0.59 | 49.0 | 5.01e-01 | 90.7% | 99.3% |
| 3690563 | 150.1.1.81 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › SOG2 | 0.58 | 49.0 | 5.05e-01 | 92.1% | 100.0% |
| 4957532 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.58 | 48.0 | 4.99e-01 | 100.0% | 95.4% |
| 3503768 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.58 | 51.0 | 4.99e-01 | 96.4% | 94.0% |
| 3544151 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.57 | 36.0 | 3.32e-01 | 100.0% | 48.9% |
| 3841584 | 633.21.1.44 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › SCAMP | 0.57 | 51.0 | 5.04e-01 | 97.1% | 98.6% |
| 3407718 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.57 | 35.0 | 3.72e-01 | 70.7% | 67.2% |
| 3550685 | 4177.1.1.38 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Tektin | 0.57 | 42.0 | 3.97e-01 | 77.9% | 95.4% |
| 3189717 | 632.22.1.196 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › ALIX_LYPXL_bnd | 0.56 | 40.0 | 3.90e-01 | 74.3% | 90.6% |
| 3476581 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 50.0 | 4.43e-01 | 98.6% | 93.7% |
| 3719886 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.55 | 48.0 | 4.90e-01 | 99.3% | 98.6% |
| 3245184 | 601.14.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › PF31009 | 0.55 | 47.0 | 4.72e-01 | 94.3% | 97.2% |
| 3971969 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.55 | 42.0 | 4.28e-01 | 98.6% | 83.0% |
| 3490726 | 5050.1.1.6 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › OATP | 0.55 | 48.0 | 4.13e-01 | 96.4% | 94.7% |
| 3626951 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.54 | 49.0 | 4.79e-01 | 100.0% | 100.0% |
| 3972145 | 5069.1.1.29 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF2214 | 0.54 | 38.0 | 3.84e-01 | 72.9% | 75.9% |
| 3610599 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 48.0 | 4.12e-01 | 98.6% | 88.9% |
| 3512307 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.54 | 47.0 | 4.52e-01 | 97.1% | 96.2% |
| 3402026 | 2004.1.1.199 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23,SbcC_Walker_B | 0.54 | 41.0 | 2.74e-01 | 78.6% | 25.8% |
| 5001143 | 601.7.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like | 0.53 | 38.0 | 3.83e-01 | 73.6% | 78.6% |
| 3578008 | 601.1.2.100 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PF31009 | 0.53 | 44.0 | 4.29e-01 | 91.4% | 90.3% |
| 3618565 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 46.0 | 4.76e-01 | 98.6% | 100.0% |
| 3689578 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.53 | 39.0 | 3.61e-01 | 77.1% | 72.8% |
| 5032686 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 46.0 | 4.20e-01 | 98.6% | 97.9% |
| 3894393 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.52 | 42.0 | 4.12e-01 | 92.1% | 79.3% |
| 3546316 | 3922.1.1.186 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › WWC1 | 0.52 | 38.0 | 3.49e-01 | 75.7% | 94.6% |
| 3697355 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.52 | 33.0 | 3.23e-01 | 100.0% | 56.8% |
| 4012748 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.52 | 39.0 | 3.07e-01 | 77.9% | 85.8% |
| 3286952 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.52 | 46.0 | 3.67e-01 | 100.0% | 100.0% |
| 3586523 | 604.12.1.45 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › PPP1R21_helical | 0.51 | 46.0 | 4.26e-01 | 97.9% | 88.0% |
| 3213281 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.51 | 32.0 | 2.63e-01 | 99.3% | 32.2% |
| 3974430 | 601.4.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 | 0.51 | 35.0 | 3.60e-01 | 75.0% | 70.0% |
| 4987042 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.51 | 36.0 | 3.72e-01 | 72.1% | 77.0% |
| 3240132 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.51 | 40.0 | 3.31e-01 | 100.0% | 48.5% |
| 3692753 | 5086.1.1.12 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Uds1 | 0.50 | 35.0 | 3.44e-01 | 100.0% | 66.0% |
D4
medium
residues 322-404
Domain cluster:
representative
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4dwnA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.64 | 55.0 | 5.31e-01 | 100.0% | 95.9% |
| 1wixA01 | 1.10.418.10 | Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Calponin-like domain | 0.61 | 47.0 | 3.91e-01 | 84.3% | 99.3% |
| 2zopA00 | 1.10.520.30 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain | 0.61 | 48.0 | 4.41e-01 | 86.7% | 65.2% |
| 3lkdB01 | 1.20.1260.30 | Mainly Alpha › Up-down Bundle › Ferritin › N6 adenine-specific DNA methyltransferase, N-terminal domain | 0.60 | 46.0 | 3.57e-01 | 83.1% | 50.3% |
| 3hzjA03 | 1.10.472.80 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Ypt/Rab-GAP domain of gyp1p, domain 3 | 0.60 | 47.0 | 3.86e-01 | 84.3% | 51.7% |
| 5n13A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.59 | 50.0 | 4.68e-01 | 98.8% | 99.1% |
| 1rw1A00 | 3.40.30.10 | Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin | 0.58 | 43.0 | 3.89e-01 | 100.0% | 57.9% |
| 1u61A00 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.57 | 49.0 | 4.29e-01 | 100.0% | 63.0% |
| 6ifsB02 | 1.10.8.100 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › rRNA adenine dimethylase, C-terminal domain | 0.56 | 41.0 | 4.36e-01 | 85.5% | 90.1% |
| 1werA02 | 1.10.506.10 | Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › GTPase Activation - p120gap; domain 1 | 0.56 | 47.0 | 4.00e-01 | 97.6% | 93.9% |
| 2dkwA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.55 | 46.0 | 4.09e-01 | 97.6% | 72.5% |
| 1dm1A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 47.0 | 3.98e-01 | 100.0% | 72.6% |
| 2i6hA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.54 | 36.0 | 3.43e-01 | 72.3% | 57.3% |
| 2qwoB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.54 | 42.0 | 4.15e-01 | 92.8% | 78.3% |
| 4oiyA01 | 1.10.220.20 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › | 0.54 | 37.0 | 3.75e-01 | 71.1% | 80.2% |
| 4ga6A02 | 1.20.970.50 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › | 0.53 | 36.0 | 3.01e-01 | 71.1% | 55.3% |
| 1bccH00 | 1.10.287.20 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain | 0.52 | 35.0 | 3.83e-01 | 100.0% | 87.9% |
| 4dxwA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 38.0 | 3.55e-01 | 89.2% | 59.8% |
| 3onkA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.50 | 36.0 | 3.08e-01 | 74.7% | 83.2% |
| 6tblB01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.50 | 36.0 | 3.28e-01 | 74.7% | 93.7% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3627112 | 109.26.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains | 0.66 | 57.0 | 3.43e-01 | 100.0% | 24.8% |
| 3583740 | 109.26.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains › Nuclear pore complex component Nup133/Nup170/Nup157 C-terminal domains | 0.64 | 55.0 | 3.96e-01 | 98.8% | 37.2% |
| 5055289 | 309.1.1.15 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › DEAD_assoc | 0.57 | 49.0 | 3.82e-01 | 97.6% | 86.3% |
| 5032535 | 306.3.1.6 ↗ | a+b two layers › Glucose permease domain IIB-like › eIF1-like › eIF1-like › DEAD_assoc | 0.56 | 46.0 | 3.77e-01 | 94.0% | 94.1% |
| 4932304 | 309.1.1.15 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › DEAD_assoc | 0.55 | 46.0 | 3.67e-01 | 95.2% | 86.9% |
| 4990132 | 309.1.1.15 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › DEAD_assoc | 0.54 | 46.0 | 3.58e-01 | 97.6% | 86.2% |
| 3286362 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 44.0 | 3.43e-01 | 92.8% | 82.1% |
| 3747265 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.52 | 44.0 | 3.86e-01 | 95.2% | 80.0% |
| 3634652 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.52 | 43.0 | 3.16e-01 | 94.0% | 74.6% |
| 4013099 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 42.0 | 3.11e-01 | 94.0% | 74.2% |
| 4961745 | 7516.1.1.79 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glyco_trans_2_3 | 0.51 | 42.0 | 2.88e-01 | 100.0% | 32.6% |
| 5076868 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.51 | 41.0 | 3.23e-01 | 94.0% | 80.5% |
| 4558305 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.50 | 41.0 | 3.10e-01 | 94.0% | 77.4% |
| 3781311 | 3877.1.1.1 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC › 60KD_IMP | 0.50 | 40.0 | 3.03e-01 | 85.5% | 42.0% |
| 3171689 | 603.1.1.105 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 | 0.50 | 35.0 | 3.14e-01 | 73.5% | 80.0% |
D5
medium
residues 405-481
Domain cluster:
representative
CATH (9)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.56 | 40.0 | 3.38e-01 | 75.3% | 82.7% |
| 3pvuA02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.55 | 39.0 | 3.93e-01 | 75.3% | 85.0% |
| 1txuA01 | 1.10.246.120 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.54 | 43.0 | 4.09e-01 | 89.6% | 95.7% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 39.0 | 3.03e-01 | 88.3% | 32.6% |
| 2bl7A00 | 1.20.1440.50 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Ta0600-like | 0.53 | 40.0 | 4.02e-01 | 84.4% | 89.9% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.52 | 36.0 | 3.42e-01 | 74.0% | 88.4% |
| 2mw2A00 | 1.20.1280.40 | Mainly Alpha › Up-down Bundle › Monooxygenase › HHA | 0.51 | 39.0 | 4.15e-01 | 90.9% | 97.0% |
| 1jq5A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.51 | 42.0 | 3.21e-01 | 97.4% | 90.8% |
| 1t33A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 39.0 | 3.27e-01 | 90.9% | 66.5% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5011247 | 5060.1.1.1 ↗ | alpha bundles › V-type ATP synthase subunit C › V-type ATP synthase subunit C › V-type ATP synthase subunit C › vATP-synt_AC39 | 0.63 | 44.0 | 2.93e-01 | 72.7% | 91.3% |
| 3480380 | 592.1.1.0 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain | 0.58 | 45.0 | 4.07e-01 | 87.0% | 84.5% |
| 4023080 | 206.1.1.82 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › DUF7580 | 0.57 | 45.0 | 3.02e-01 | 87.0% | 80.9% |
| 3420693 | 109.4.1.420 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR | 0.57 | 44.0 | 3.58e-01 | 87.0% | 65.0% |
| 4677545 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.57 | 41.0 | 4.51e-01 | 75.3% | 96.7% |
| 4680974 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.56 | 41.0 | 3.84e-01 | 76.6% | 66.3% |
| 4099504 | 604.17.1.0 ↗ | alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like | 0.56 | 39.0 | 4.22e-01 | 74.0% | 96.7% |
| 3262738 | 592.1.1.2 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › Helicase_PWI | 0.54 | 46.0 | 4.05e-01 | 100.0% | 84.0% |
| 3506555 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 41.0 | 3.72e-01 | 90.9% | 64.5% |
| 4498171 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.51 | 38.0 | 3.84e-01 | 80.5% | 85.3% |