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PH2015_20_sub10_scaffold_1_prodigal-single.1__X__X__00054
Bact-VirPH2015_20_sub10_scaffold_1_prodigal-single.1__X__X__00054
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 35-88
Domain cluster:
representative
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.79 | 70.0 | 5.22e-01 | 98.1% | 60.2% |
| 8d7hD01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.78 | 71.0 | 4.88e-01 | 100.0% | 40.5% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 68.0 | 5.47e-01 | 96.3% | 73.5% |
| 4u1cA01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.78 | 59.0 | 6.07e-01 | 96.3% | 86.5% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.77 | 67.0 | 5.92e-01 | 98.1% | 74.4% |
| 1aueB00 | 1.20.120.150 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › FKBP12-rapamycin binding domain | 0.77 | 61.0 | 5.05e-01 | 88.9% | 50.0% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.76 | 66.0 | 4.92e-01 | 98.1% | 77.8% |
| 2xokP00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.75 | 61.0 | 5.52e-01 | 90.7% | 73.0% |
| 2y1vA04 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.75 | 65.0 | 4.47e-01 | 98.1% | 29.2% |
| 7utzR02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.75 | 65.0 | 4.11e-01 | 98.1% | 20.1% |
| 3fxdC00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.75 | 61.0 | 6.33e-01 | 98.1% | 98.0% |
| 2hjmA01 | 1.20.120.460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like | 0.74 | 66.0 | 5.67e-01 | 100.0% | 64.0% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 63.0 | 5.77e-01 | 96.3% | 76.1% |
| 2o36A01 | 1.20.1050.40 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 | 0.74 | 62.0 | 4.76e-01 | 96.3% | 43.0% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.73 | 64.0 | 5.38e-01 | 98.1% | 65.6% |
| 2kp8A00 | 1.20.5.170 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.72 | 58.0 | 5.36e-01 | 92.6% | 76.4% |
| 4etrB00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.72 | 62.0 | 4.85e-01 | 100.0% | 80.3% |
| 3txsC01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.72 | 62.0 | 5.62e-01 | 98.1% | 73.3% |
| 1jkvA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.72 | 62.0 | 4.24e-01 | 100.0% | 78.2% |
| 3sjqC00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.72 | 59.0 | 5.29e-01 | 96.3% | 71.2% |
| 4fvmA06 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.71 | 54.0 | 5.58e-01 | 90.7% | 95.8% |
| 2x2vA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.70 | 56.0 | 5.30e-01 | 92.6% | 92.6% |
| 1z0pA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 59.0 | 5.40e-01 | 98.1% | 79.5% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.70 | 61.0 | 5.26e-01 | 96.3% | 67.1% |
| 1b3qA01 | 1.10.287.560 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain | 0.70 | 58.0 | 5.58e-01 | 98.1% | 82.3% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 58.0 | 4.35e-01 | 100.0% | 42.3% |
| 2zueA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.69 | 58.0 | 4.56e-01 | 98.1% | 54.6% |
| 1i6zA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.69 | 58.0 | 4.44e-01 | 100.0% | 61.5% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.68 | 55.0 | 4.62e-01 | 96.3% | 52.9% |
| 1ma1A01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.67 | 56.0 | 5.38e-01 | 98.1% | 96.9% |
| 3lphC00 | 6.10.140.630 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 57.0 | 5.62e-01 | 98.1% | 96.6% |
| 4errB00 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 54.0 | 4.79e-01 | 96.3% | 67.5% |
| 1luwA01 | 1.10.287.990 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain | 0.64 | 52.0 | 5.05e-01 | 98.1% | 96.9% |
| 2rklF00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.63 | 46.0 | 4.71e-01 | 85.2% | 88.5% |
| 2g7lA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.60 | 53.0 | 3.57e-01 | 100.0% | 27.4% |
| 4ex8A00 | 3.40.1790.10 | Alpha Beta › 3-Layer(aba) Sandwich › Indigoidine synthase fold › Indigoidine synthase domain | 0.59 | 52.0 | 3.27e-01 | 100.0% | 40.2% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.59 | 46.0 | 3.76e-01 | 96.3% | 44.0% |
| 6axgA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.58 | 46.0 | 3.95e-01 | 87.0% | 52.8% |
| 6f1eA01 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.57 | 46.0 | 3.61e-01 | 100.0% | 44.6% |
| 6axfA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.57 | 47.0 | 3.81e-01 | 100.0% | 72.6% |
| 4iv6B01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.55 | 44.0 | 3.53e-01 | 90.7% | 54.3% |
ECOD (46)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3906133 | 633.21.1.4 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › Cg6151-P | 0.82 | 68.0 | 5.25e-01 | 96.3% | 42.6% |
| 4974229 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.80 | 70.0 | 4.77e-01 | 98.1% | 29.1% |
| 3213478 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.80 | 70.0 | 5.98e-01 | 98.1% | 61.2% |
| 3619577 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.80 | 71.0 | 5.97e-01 | 98.1% | 83.3% |
| 5002748 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.78 | 67.0 | 6.01e-01 | 96.3% | 82.7% |
| 4521514 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.78 | 69.0 | 6.15e-01 | 98.1% | 82.7% |
| 3776400 | 192.5.1.1 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1 | 0.77 | 68.0 | 5.95e-01 | 98.1% | 73.8% |
| 3674246 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.76 | 67.0 | 4.93e-01 | 98.1% | 49.3% |
| 4029817 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.76 | 59.0 | 5.54e-01 | 98.1% | 69.2% |
| 3460434 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.76 | 67.0 | 4.97e-01 | 98.1% | 39.3% |
| 3697794 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.76 | 63.0 | 5.00e-01 | 92.6% | 46.4% |
| 3377495 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.76 | 65.0 | 4.98e-01 | 98.1% | 43.3% |
| 3410408 | 3712.1.1.0 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 › Mediator of RNA polymerase II transcription subunit 11 | 0.75 | 65.0 | 5.58e-01 | 96.3% | 65.5% |
| 3920438 | 150.3.1.4 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › IFN-gamma | 0.75 | 64.0 | 4.59e-01 | 96.3% | 39.4% |
| 4950709 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.75 | 64.0 | 6.09e-01 | 98.1% | 89.2% |
| 3229788 | 3470.1.1.0 ↗ | extended segments › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain › Glycophorin-A transmembrane domain | 0.74 | 62.0 | 6.03e-01 | 98.1% | 83.3% |
| 3413114 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.74 | 63.0 | 6.01e-01 | 98.1% | 84.6% |
| 4026623 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.74 | 64.0 | 4.28e-01 | 98.1% | 57.6% |
| 3901696 | 192.8.1.240 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › HR1 | 0.74 | 63.0 | 5.49e-01 | 98.1% | 64.7% |
| 3491418 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.73 | 62.0 | 5.60e-01 | 96.3% | 72.0% |
| 5050359 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.73 | 60.0 | 5.62e-01 | 96.3% | 77.1% |
| 3958049 | 633.6.1.0 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like | 0.72 | 63.0 | 4.86e-01 | 98.1% | 53.3% |
| 4055485 | 192.4.1.1 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Ribosomal_L29 | 0.72 | 62.0 | 5.72e-01 | 98.1% | 78.6% |
| 1487362 | 3930.2.1.1 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in endoribonuclease Dicer › Helical bundle in endoribonuclease Dicer › Dicer_PBD | 0.72 | 63.0 | 4.90e-01 | 100.0% | 47.1% |
| 3674753 | 192.1.1.23 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › DUF3493 | 0.72 | 62.0 | 5.71e-01 | 98.1% | 78.6% |
| 4029952 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.71 | 61.0 | 4.25e-01 | 100.0% | 68.6% |
| 3684478 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.70 | 57.0 | 5.29e-01 | 92.6% | 72.9% |
| 4954644 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.70 | 58.0 | 4.57e-01 | 98.1% | 43.3% |
| 4652719 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.70 | 58.0 | 4.89e-01 | 96.3% | 60.0% |
| 5083225 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.69 | 56.0 | 5.36e-01 | 96.3% | 83.1% |
| 3805103 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.69 | 59.0 | 4.81e-01 | 100.0% | 72.4% |
| 3346653 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.69 | 58.0 | 4.79e-01 | 100.0% | 72.4% |
| 3424212 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.68 | 57.0 | 5.11e-01 | 96.3% | 68.8% |
| 5060546 | 633.15.1.2 ↗ | alpha bundles › Bromodomain-like › alpha-ketoacid dehydrogenase kinase-N › alpha-ketoacid dehydrogenase kinase-N › Alpha_Helical | 0.67 | 55.0 | 4.39e-01 | 96.3% | 55.0% |
| 3914715 | 605.1.1.235 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › BicD | 0.67 | 51.0 | 4.59e-01 | 85.2% | 60.0% |
| 5049082 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.67 | 56.0 | 3.84e-01 | 100.0% | 64.4% |
| 3663036 | 604.1.1.125 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SYNRG_C | 0.66 | 54.0 | 3.83e-01 | 98.1% | 43.7% |
| 3450834 | 611.3.1.0 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.65 | 55.0 | 4.71e-01 | 100.0% | 88.3% |
| 3809927 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.65 | 52.0 | 4.97e-01 | 98.1% | 75.4% |
| 3780401 | 192.8.1.6 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › BicD | 0.64 | 50.0 | 3.66e-01 | 87.0% | 29.7% |
| 3928795 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.63 | 50.0 | 4.25e-01 | 92.6% | 54.7% |
| 3516381 | 5001.1.1.63 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab | 0.62 | 52.0 | 3.22e-01 | 100.0% | 27.7% |
| 3325799 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.61 | 51.0 | 4.03e-01 | 100.0% | 56.0% |
| 3894983 | 4156.1.1.2 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_N,HA2_C | 0.58 | 51.0 | 3.50e-01 | 100.0% | 53.8% |
| 2330449 | 150.3.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine | 0.56 | 44.0 | 3.63e-01 | 100.0% | 47.2% |
| 3636358 | 5055.1.1.0 ↗ | extended segments › Small-conductance potassium channel › Small-conductance potassium channel › Small-conductance potassium channel | 0.53 | 38.0 | 3.77e-01 | 90.7% | 73.8% |