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PH2015_20_sub10_scaffold_1_prodigal-single.1__X__X__00139
Bact-VirPH2015_20_sub10_scaffold_1_prodigal-single.1__X__X__00139
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-90
Domain cluster:
rep: PH2017_36_ELK_O_B_scaffold_2_prodigal-single.1__X__X__00340__D5-88
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2cs7A00 | 3.10.50.90 | Alpha Beta › Roll › Chitinase A; domain 3 › | 0.64 | 34.0 | 4.14e-01 | 92.0% | 81.8% |
| 6uf3A00 | 3.40.630.190 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › LCP protein | 0.55 | 46.0 | 3.43e-01 | 96.6% | 87.8% |
| 3oyyA02 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.52 | 35.0 | 3.88e-01 | 70.5% | 93.8% |
| 3r1wA00 | 2.160.10.10 | Mainly Beta › 3 Solenoid › UDP N-Acetylglucosamine Acyltransferase; domain 1 › Hexapeptide repeat proteins | 0.51 | 39.0 | 3.12e-01 | 81.8% | 72.2% |
| 1obbA00 | 3.90.1820.10 | Alpha Beta › Alpha-Beta Complex › LDH C-terminal domain-like › AglA-like glucosidase | 0.51 | 39.0 | 2.53e-01 | 85.2% | 75.9% |
| 1tfrA01 | 3.40.50.1010 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease | 0.50 | 41.0 | 3.20e-01 | 92.0% | 74.8% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3484879 | 4076.1.1.0 ↗ | a+b two layers › L9 N-domain-like › L9 N-domain-like › L9 N-domain-like | 0.69 | 39.0 | 5.06e-01 | 79.5% | 100.0% |
| 3988598 | 4.16.1.1 ↗ | beta barrels › SH3 › PhtA domain-like › PhtA domain-like › Strep_his_triad | 0.63 | 34.0 | 3.84e-01 | 92.0% | 69.2% |
| 3988577 | 4.16.1.1 ↗ | beta barrels › SH3 › PhtA domain-like › PhtA domain-like › Strep_his_triad | 0.62 | 33.0 | 3.85e-01 | 90.9% | 73.3% |
| 3988565 | 4.16.1.0 ↗ | beta barrels › SH3 › PhtA domain-like › PhtA domain-like | 0.61 | 33.0 | 4.10e-01 | 92.0% | 97.8% |
| 3384387 | 1133.1.1.2 ↗ | beta sandwiches › Immunomodulator A46 N-terminal domain › Immunomodulator A46 N-terminal domain › Immunomodulator A46 N-terminal domain › DUF674 | 0.57 | 41.0 | 2.88e-01 | 75.0% | 49.8% |
| 3487937 | 327.11.2.0 ↗ | a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) | 0.54 | 29.0 | 3.38e-01 | 97.7% | 73.3% |
| 4929722 | 221.4.1.1 ↗ | a+b two layers › beta-Grasp › Nudix › Nudix › NUDIX | 0.51 | 38.0 | 3.02e-01 | 79.5% | 70.3% |
| 3512115 | 2485.1.1.1 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin | 0.51 | 25.0 | 2.76e-01 | 93.2% | 53.8% |
| 2161921 | 3016.1.1.0 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases | 0.50 | 29.0 | 2.96e-01 | 83.0% | 56.5% |
| 4029099 | 304.9.1.0 ↗ | a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD | 0.50 | 35.0 | 3.04e-01 | 72.7% | 77.8% |
D2
high
residues 98-209
Domain cluster:
rep: PH2017_36_ELK_O_B_scaffold_2_prodigal-single.1__X__X__00340__D93-206
CATH (28)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3h0dB02 | 1.10.1200.150 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Transcriptional repressor of class III stress genes, C-terminal domain | 0.75 | 38.0 | 4.39e-01 | 100.0% | 66.7% |
| 4fcyA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.71 | 33.0 | 3.89e-01 | 80.4% | 62.8% |
| 2y39A00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.68 | 44.0 | 4.50e-01 | 92.0% | 66.4% |
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.66 | 42.0 | 5.04e-01 | 80.4% | 96.1% |
| 5zw7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.64 | 46.0 | 4.19e-01 | 100.0% | 54.6% |
| 4m70I00 | 1.20.5.4130 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.64 | 43.0 | 4.43e-01 | 100.0% | 72.2% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.64 | 39.0 | 4.05e-01 | 76.8% | 65.7% |
| 2e9xA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 46.0 | 4.41e-01 | 89.3% | 65.6% |
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.63 | 41.0 | 4.30e-01 | 99.1% | 72.5% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 39.0 | 4.06e-01 | 83.9% | 66.4% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.62 | 40.0 | 3.80e-01 | 100.0% | 54.1% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.62 | 43.0 | 3.53e-01 | 100.0% | 39.5% |
| 4flaC00 | 6.10.250.2560 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.62 | 47.0 | 4.51e-01 | 82.1% | 70.1% |
| 2ddhA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.61 | 47.0 | 4.45e-01 | 100.0% | 68.2% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.60 | 45.0 | 4.66e-01 | 83.0% | 84.5% |
| 2y1eA03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.60 | 35.0 | 3.90e-01 | 100.0% | 73.6% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 42.0 | 4.45e-01 | 89.3% | 81.4% |
| 5u1aL00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 52.0 | 4.61e-01 | 100.0% | 78.9% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 45.0 | 3.51e-01 | 83.0% | 40.7% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.56 | 48.0 | 3.49e-01 | 95.5% | 48.8% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 50.0 | 4.07e-01 | 99.1% | 74.8% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 39.0 | 3.94e-01 | 92.9% | 73.2% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.54 | 45.0 | 3.85e-01 | 100.0% | 54.8% |
| 3dytA02 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.54 | 48.0 | 4.08e-01 | 100.0% | 84.7% |
| 6lumD01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.52 | 42.0 | 4.07e-01 | 98.2% | 78.4% |
| 1st6A03 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.52 | 40.0 | 3.22e-01 | 83.0% | 69.0% |
| 2wdqD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.51 | 39.0 | 4.08e-01 | 100.0% | 87.6% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 42.0 | 3.59e-01 | 89.3% | 56.6% |
ECOD (40)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4034224 | 632.19.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Choline binding protein A › Choline binding protein A › DUF1542 | 0.85 | 50.0 | 6.08e-01 | 100.0% | 88.0% |
| 5075398 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.73 | 57.0 | 5.00e-01 | 100.0% | 55.8% |
| 3248839 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.72 | 53.0 | 5.23e-01 | 100.0% | 71.7% |
| 3725707 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.70 | 43.0 | 3.76e-01 | 100.0% | 41.2% |
| 4933188 | 5069.1.3.1 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt | 0.69 | 49.0 | 5.25e-01 | 95.5% | 86.3% |
| 3591771 | 611.8.1.0 ↗ | alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 | 0.68 | 51.0 | 4.64e-01 | 100.0% | 58.7% |
| 3696454 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.67 | 35.0 | 3.24e-01 | 79.5% | 39.3% |
| 5057882 | 4163.1.1.1 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 | 0.65 | 41.0 | 4.08e-01 | 71.4% | 60.0% |
| 4948369 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.64 | 51.0 | 4.73e-01 | 100.0% | 68.1% |
| 3875941 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.63 | 50.0 | 4.40e-01 | 100.0% | 57.6% |
| 3709425 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.61 | 57.0 | 4.75e-01 | 100.0% | 71.9% |
| 3612915 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 41.0 | 4.30e-01 | 92.9% | 74.3% |
| 3977410 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.60 | 45.0 | 4.85e-01 | 81.2% | 91.6% |
| 4998773 | 3755.3.1.305 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Rad50_zn_hook | 0.59 | 46.0 | 3.87e-01 | 83.0% | 88.7% |
| 3599997 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.59 | 50.0 | 2.94e-01 | 91.1% | 71.3% |
| 3711734 | 3755.3.1.297 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › KIF9 | 0.58 | 45.0 | 3.95e-01 | 82.1% | 55.2% |
| 3699443 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.58 | 46.0 | 4.63e-01 | 83.9% | 83.5% |
| 3796694 | 5050.1.1.22 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1_like | 0.58 | 44.0 | 3.76e-01 | 79.5% | 74.9% |
| 4927311 | 5069.1.3.1 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt | 0.58 | 46.0 | 4.66e-01 | 99.1% | 86.4% |
| 4347645 | 141.1.1.8 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_syn_C_2 | 0.58 | 43.0 | 3.03e-01 | 79.5% | 26.1% |
| 3810801 | 632.22.1.139 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › KIF21A_4th | 0.57 | 45.0 | 4.07e-01 | 82.1% | 72.7% |
| 3989298 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.57 | 52.0 | 4.49e-01 | 100.0% | 65.5% |
| 3298709 | 605.1.1.141 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › Rx_N | 0.57 | 47.0 | 4.52e-01 | 100.0% | 78.4% |
| 3462885 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.56 | 49.0 | 4.16e-01 | 95.5% | 89.7% |
| 3892960 | 3291.1.1.86 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PL48 | 0.56 | 51.0 | 4.76e-01 | 100.0% | 92.9% |
| 4276314 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.56 | 42.0 | 3.31e-01 | 81.2% | 39.5% |
| 5055626 | 1076.1.1.0 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related | 0.56 | 46.0 | 4.18e-01 | 100.0% | 66.0% |
| 3871834 | 5086.1.1.99 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ApoL | 0.56 | 38.0 | 4.45e-01 | 74.1% | 98.8% |
| 3212246 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.55 | 49.0 | 4.30e-01 | 100.0% | 74.9% |
| 3607135 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.55 | 43.0 | 4.07e-01 | 82.1% | 72.6% |
| 5002671 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.55 | 43.0 | 3.81e-01 | 82.1% | 60.0% |
| 3358852 | 3755.4.1.62 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF31016 | 0.55 | 43.0 | 3.81e-01 | 82.1% | 60.6% |
| 3961947 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.54 | 49.0 | 4.39e-01 | 100.0% | 77.4% |
| 3611631 | 3559.1.1.0 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 | 0.53 | 38.0 | 3.83e-01 | 91.1% | 72.2% |
| 3643461 | 601.19.1.35 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › PF28744 | 0.53 | 48.0 | 4.56e-01 | 100.0% | 85.4% |
| 3596488 | 3737.1.1.0 ↗ | alpha duplicates or obligate multimers › Major allergen Bla g 1 tandem repeats › Major allergen Bla g 1 tandem repeats › Major allergen Bla g 1 tandem repeats | 0.53 | 44.0 | 4.24e-01 | 92.9% | 80.0% |
| 3513888 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.52 | 41.0 | 3.68e-01 | 83.0% | 64.5% |
| 4556778 | 3919.1.1.2 ↗ | alpha duplicates or obligate multimers › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › N-terminal domain of COMMD9 › COMM_HN | 0.52 | 35.0 | 3.53e-01 | 89.3% | 66.1% |
| 3653908 | 101.1.10.1 ↗ | alpha arrays › HTH › HTH › Cyclin-like › Cyclin_N | 0.51 | 35.0 | 3.33e-01 | 100.0% | 59.3% |
| 3612306 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.50 | 45.0 | 4.13e-01 | 100.0% | 75.7% |