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PH2017_36_ELK_O_B_scaffold_2_prodigal-single.1__X__X__00340
Bact-VirPH2017_36_ELK_O_B_scaffold_2_prodigal-single.1__X__X__00340
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 5-88
Domain cluster:
representative
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4hh2B03 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.64 | 33.0 | 3.14e-01 | 82.1% | 41.0% |
| 7d44I01 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.64 | 48.0 | 3.40e-01 | 81.0% | 35.6% |
| 1mw7A02 | 3.30.70.980 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain | 0.63 | 46.0 | 4.61e-01 | 100.0% | 74.7% |
| 1ln0A00 | 3.40.1440.10 | Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease | 0.62 | 44.0 | 4.31e-01 | 75.0% | 92.4% |
| 3m7aA01 | 2.60.120.1140 | Mainly Beta › Sandwich › Jelly Rolls › Protein of unknown function DUF192 | 0.61 | 41.0 | 3.50e-01 | 79.8% | 41.9% |
| 1ll8A00 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.61 | 33.0 | 3.02e-01 | 83.3% | 38.6% |
| 5yrpA00 | 3.20.20.450 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › EAL domain | 0.57 | 42.0 | 3.15e-01 | 78.6% | 98.2% |
| 4jg5A01 | 2.60.40.2580 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.57 | 42.0 | 3.33e-01 | 83.3% | 37.7% |
| 6pd2A01 | 3.90.550.10 | Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A | 0.56 | 40.0 | 2.94e-01 | 75.0% | 84.7% |
| 2b9lA01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.56 | 36.0 | 2.95e-01 | 82.1% | 35.0% |
| 4lrzE01 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.56 | 41.0 | 3.24e-01 | 78.6% | 68.0% |
| 5llwA01 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.53 | 30.0 | 2.99e-01 | 82.1% | 48.9% |
| 1wh2A01 | 3.30.1490.40 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › GYF domain | 0.52 | 29.0 | 3.23e-01 | 77.4% | 70.5% |
| 1obbA00 | 3.90.1820.10 | Alpha Beta › Alpha-Beta Complex › LDH C-terminal domain-like › AglA-like glucosidase | 0.51 | 43.0 | 2.75e-01 | 96.4% | 75.3% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3592890 | 7516.1.1.0 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases | 0.67 | 51.0 | 3.40e-01 | 81.0% | 27.9% |
| 3718968 | 7516.1.1.1 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase | 0.67 | 51.0 | 3.42e-01 | 81.0% | 29.8% |
| 3390846 | 7516.1.1.1 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase | 0.66 | 50.0 | 3.47e-01 | 81.0% | 33.3% |
| 5047292 | 223.1.1.14 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 | 0.64 | 35.0 | 3.18e-01 | 84.5% | 40.0% |
| 3184485 | 76.1.1.0 ↗ | beta duplicates or obligate multimers › beta-Prism I › beta-Prism I › beta-Prism I | 0.61 | 48.0 | 4.47e-01 | 95.2% | 66.7% |
| 3502848 | 7516.1.1.0 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases | 0.61 | 46.0 | 3.18e-01 | 81.0% | 35.5% |
| 3492510 | 7516.1.1.0 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases | 0.60 | 46.0 | 3.22e-01 | 82.1% | 35.6% |
| 3926589 | 7516.1.1.1 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase | 0.58 | 44.0 | 2.93e-01 | 81.0% | 40.3% |
| 3188282 | 2002.1.1.0 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels | 0.54 | 43.0 | 2.70e-01 | 86.9% | 93.3% |
| 3800762 | 2011.1.1.3 ↗ | a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M17 | 0.53 | 41.0 | 2.94e-01 | 83.3% | 52.5% |
D2
high
residues 93-206
Domain cluster:
representative
CATH (63)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.80 | 46.0 | 4.86e-01 | 83.3% | 63.7% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.78 | 66.0 | 6.02e-01 | 100.0% | 70.5% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.77 | 65.0 | 5.80e-01 | 100.0% | 64.4% |
| 4q5nA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.77 | 38.0 | 3.86e-01 | 71.9% | 47.3% |
| 3lbxB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 45.0 | 4.70e-01 | 78.1% | 66.4% |
| 3a7mA01 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.72 | 42.0 | 4.33e-01 | 72.8% | 60.0% |
| 2fonA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 53.0 | 5.06e-01 | 91.2% | 66.7% |
| 2p5tA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.72 | 47.0 | 5.25e-01 | 100.0% | 83.7% |
| 2ddhA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.72 | 53.0 | 5.10e-01 | 91.2% | 67.4% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.71 | 41.0 | 4.32e-01 | 76.3% | 63.1% |
| 3fd9A03 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.70 | 45.0 | 5.41e-01 | 72.8% | 100.0% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 48.0 | 4.66e-01 | 79.8% | 64.3% |
| 6p73A02 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.69 | 49.0 | 4.55e-01 | 100.0% | 58.0% |
| 1k32A03 | 3.30.750.44 | Alpha Beta › 2-Layer Sandwich › Transcription Regulator spoIIAA › | 0.69 | 41.0 | 4.91e-01 | 100.0% | 91.7% |
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.69 | 50.0 | 5.25e-01 | 77.2% | 83.5% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.68 | 35.0 | 3.93e-01 | 80.7% | 61.5% |
| 1qsdA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 45.0 | 4.71e-01 | 83.3% | 74.5% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.67 | 41.0 | 4.27e-01 | 78.9% | 66.7% |
| 3anwA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 42.0 | 4.26e-01 | 83.3% | 63.7% |
| 4ke2A00 | 6.10.140.1860 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 52.0 | 4.26e-01 | 82.5% | 51.5% |
| 4mh6A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.66 | 51.0 | 4.57e-01 | 82.5% | 86.8% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.65 | 59.0 | 5.00e-01 | 100.0% | 86.7% |
| 3r84B00 | 6.10.280.160 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 | 0.65 | 44.0 | 5.10e-01 | 76.3% | 98.8% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.65 | 59.0 | 5.11e-01 | 100.0% | 81.7% |
| 3o6xA02 | 1.20.120.1560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.65 | 58.0 | 5.36e-01 | 100.0% | 76.4% |
| 3ofnY00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.65 | 49.0 | 4.95e-01 | 80.7% | 87.0% |
| 4ie5A02 | 1.20.58.1470 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › FTO C-terminal domain | 0.64 | 42.0 | 4.06e-01 | 83.3% | 56.7% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.64 | 39.0 | 4.16e-01 | 86.8% | 67.6% |
| 4iloA00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 50.0 | 3.93e-01 | 82.5% | 39.8% |
| 3k29A00 | 1.10.287.1700 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 50.0 | 4.45e-01 | 82.5% | 59.0% |
| 3v1vA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.64 | 44.0 | 3.20e-01 | 71.1% | 26.8% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.64 | 52.0 | 4.21e-01 | 86.8% | 94.9% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 45.0 | 4.54e-01 | 94.7% | 72.0% |
| 5i1uA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.63 | 45.0 | 3.31e-01 | 72.8% | 27.7% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.63 | 49.0 | 3.95e-01 | 82.5% | 53.8% |
| 7y9hB01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.63 | 44.0 | 3.16e-01 | 71.1% | 26.1% |
| 6tqfA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.63 | 48.0 | 3.31e-01 | 81.6% | 23.5% |
| 3kb9A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.63 | 45.0 | 3.21e-01 | 73.7% | 25.6% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.62 | 42.0 | 4.04e-01 | 100.0% | 59.4% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 45.0 | 4.66e-01 | 78.9% | 80.4% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.62 | 41.0 | 4.69e-01 | 78.1% | 95.1% |
| 5nx5B00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.62 | 43.0 | 3.23e-01 | 72.8% | 29.8% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.60 | 53.0 | 4.74e-01 | 100.0% | 69.2% |
| 4mc3A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.60 | 42.0 | 3.17e-01 | 73.7% | 28.6% |
| 5u1aL00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.60 | 51.0 | 4.58e-01 | 95.6% | 80.7% |
| 1c17M00 | 1.20.120.220 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ATP synthase, F0 complex, subunit A | 0.59 | 44.0 | 4.13e-01 | 97.4% | 62.7% |
| 8ex5A02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.59 | 46.0 | 3.67e-01 | 81.6% | 96.4% |
| 2fp1B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.59 | 40.0 | 3.56e-01 | 97.4% | 48.2% |
| 4l6rA02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.59 | 42.0 | 3.20e-01 | 89.5% | 29.5% |
| 3eyxA00 | 3.40.1050.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase | 0.58 | 33.0 | 2.70e-01 | 76.3% | 32.0% |
| 8h6qD01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.57 | 40.0 | 2.98e-01 | 73.7% | 27.0% |
| 1sigA00 | 1.10.601.10 | Mainly Alpha › Orthogonal Bundle › RNA Polymerase Primary Sigma Factor › RNA Polymerase Primary Sigma Factor | 0.57 | 46.0 | 3.38e-01 | 86.0% | 70.2% |
| 2wdqD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.56 | 41.0 | 4.24e-01 | 83.3% | 81.0% |
| 1i36A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.55 | 32.0 | 3.47e-01 | 81.6% | 66.7% |
| 2c2jA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 48.0 | 4.25e-01 | 100.0% | 82.4% |
| 2qwtA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 36.0 | 3.20e-01 | 70.2% | 77.2% |
| 4q5rA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.53 | 34.0 | 3.49e-01 | 78.1% | 65.2% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.53 | 37.0 | 3.58e-01 | 94.7% | 63.8% |
| 2w02B01 | 1.10.150.640 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle | 0.53 | 33.0 | 3.96e-01 | 86.0% | 97.3% |
| 2zcxA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 37.0 | 3.07e-01 | 73.7% | 62.4% |
| 6vydA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.52 | 38.0 | 2.82e-01 | 76.3% | 29.2% |
| 3pqaB01 | 3.40.605.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 | 0.52 | 43.0 | 3.24e-01 | 89.5% | 80.9% |
| 4fjvA02 | 1.20.1300.20 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 | 0.51 | 37.0 | 3.48e-01 | 90.4% | 60.4% |
ECOD (76)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3220791 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.82 | 57.0 | 4.67e-01 | 100.0% | 42.1% |
| 5042223 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.80 | 56.0 | 5.25e-01 | 100.0% | 59.3% |
| 3662351 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.78 | 58.0 | 5.66e-01 | 97.4% | 71.2% |
| 4059065 | 622.1.1.1 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C | 0.75 | 43.0 | 4.66e-01 | 79.8% | 65.7% |
| 3698208 | 611.7.1.0 ↗ | alpha bundles › N-cbl like › Mixed lineage kinase domain-like (MLKL) N-terminal domain › Mixed lineage kinase domain-like (MLKL) N-terminal domain | 0.75 | 55.0 | 5.09e-01 | 96.5% | 61.4% |
| 3249529 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.74 | 55.0 | 5.19e-01 | 98.2% | 65.2% |
| 4200387 | 192.7.1.3 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N | 0.74 | 44.0 | 4.98e-01 | 73.7% | 76.7% |
| 4466203 | 192.7.1.3 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N | 0.74 | 43.0 | 4.93e-01 | 71.1% | 77.6% |
| 4371507 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.73 | 49.0 | 5.27e-01 | 98.2% | 81.1% |
| 3566988 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.73 | 56.0 | 5.33e-01 | 91.2% | 70.0% |
| 1883676 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.73 | 55.0 | 4.59e-01 | 92.1% | 46.2% |
| 3745786 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.72 | 55.0 | 4.45e-01 | 92.1% | 42.3% |
| 4251267 | 192.7.1.3 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N | 0.72 | 45.0 | 4.67e-01 | 73.7% | 67.6% |
| 3355297 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.71 | 65.0 | 6.29e-01 | 98.2% | 96.8% |
| 4397328 | 604.10.1.1 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PTS_IIA | 0.71 | 47.0 | 4.81e-01 | 79.8% | 70.0% |
| 3808722 | 633.6.1.2 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › ACOX | 0.70 | 55.0 | 4.88e-01 | 94.7% | 58.7% |
| 4352409 | 375.1.1.300 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › SOAR | 0.70 | 50.0 | 4.66e-01 | 83.3% | 60.0% |
| 5035838 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.70 | 46.0 | 5.11e-01 | 100.0% | 85.6% |
| 3622487 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.69 | 48.0 | 4.96e-01 | 82.5% | 74.5% |
| 3465588 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.69 | 47.0 | 4.91e-01 | 78.9% | 75.2% |
| 4025445 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.69 | 46.0 | 4.93e-01 | 81.6% | 78.0% |
| 3553221 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.69 | 49.0 | 4.82e-01 | 100.0% | 69.2% |
| 3437911 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.69 | 60.0 | 5.79e-01 | 95.6% | 83.1% |
| 4190833 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.69 | 59.0 | 5.86e-01 | 97.4% | 88.3% |
| 3612915 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.69 | 43.0 | 4.48e-01 | 72.8% | 67.6% |
| 3316949 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.68 | 61.0 | 5.81e-01 | 99.1% | 91.9% |
| 3937801 | 4177.1.1.38 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Tektin | 0.67 | 62.0 | 5.08e-01 | 100.0% | 73.5% |
| 4025221 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.67 | 52.0 | 4.65e-01 | 82.5% | 91.9% |
| 3701245 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.67 | 46.0 | 4.69e-01 | 83.3% | 72.7% |
| 4284928 | 314.1.1.0 ↗ | a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases | 0.66 | 43.0 | 2.96e-01 | 70.2% | 21.1% |
| 5063587 | 611.9.1.0 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain | 0.66 | 38.0 | 4.43e-01 | 73.7% | 77.6% |
| 4933737 | 3567.1.1.192 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › EMC3_TMCO1 | 0.66 | 50.0 | 5.47e-01 | 79.8% | 98.9% |
| 3245015 | 3831.1.1.0 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 | 0.66 | 40.0 | 4.64e-01 | 93.9% | 85.0% |
| 3699443 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.66 | 51.0 | 5.17e-01 | 81.6% | 91.3% |
| 3939916 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.66 | 59.0 | 5.02e-01 | 100.0% | 87.9% |
| 3837996 | 1075.4.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold | 0.66 | 50.0 | 3.59e-01 | 82.5% | 28.0% |
| 4972733 | 611.2.1.0 ↗ | alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) | 0.66 | 45.0 | 4.66e-01 | 100.0% | 74.3% |
| 4235156 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.65 | 58.0 | 5.72e-01 | 100.0% | 94.2% |
| 3619641 | 604.1.1.154 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27021 | 0.65 | 41.0 | 4.23e-01 | 78.1% | 67.6% |
| 3973695 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.65 | 51.0 | 4.28e-01 | 83.3% | 52.1% |
| 4653531 | 632.1.1.14 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › EzrA | 0.65 | 45.0 | 4.63e-01 | 100.0% | 74.5% |
| 3702347 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.65 | 51.0 | 4.35e-01 | 82.5% | 82.9% |
| 4955963 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.65 | 51.0 | 4.16e-01 | 82.5% | 84.5% |
| 4001943 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.64 | 39.0 | 3.86e-01 | 75.4% | 55.8% |
| 3306718 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.64 | 50.0 | 4.12e-01 | 82.5% | 69.3% |
| 3890086 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.64 | 50.0 | 4.38e-01 | 82.5% | 56.4% |
| 4352674 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.64 | 43.0 | 4.49e-01 | 78.1% | 74.3% |
| 3482286 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.64 | 50.0 | 4.12e-01 | 82.5% | 89.5% |
| 3702176 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.64 | 51.0 | 4.76e-01 | 85.1% | 68.6% |
| 4937739 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.64 | 49.0 | 4.67e-01 | 81.6% | 83.7% |
| 3346014 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.64 | 55.0 | 4.09e-01 | 94.7% | 88.6% |
| 1807245 | 141.1.1.8 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_syn_C_2 | 0.63 | 45.0 | 3.31e-01 | 72.8% | 27.7% |
| 3958574 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.63 | 50.0 | 4.37e-01 | 82.5% | 62.4% |
| 4349607 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.63 | 47.0 | 4.86e-01 | 79.8% | 81.8% |
| 3451749 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.62 | 55.0 | 4.59e-01 | 95.6% | 75.3% |
| 3875941 | 3291.1.1.1 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Snf7 | 0.62 | 55.0 | 4.89e-01 | 98.2% | 72.1% |
| 3845975 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.62 | 45.0 | 4.90e-01 | 79.8% | 91.6% |
| 3690080 | 603.5.1.0 ↗ | alpha bundles › STAT-like › FlgN-like › FlgN-like | 0.62 | 37.0 | 3.72e-01 | 76.3% | 57.1% |
| 4569106 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.61 | 48.0 | 3.19e-01 | 83.3% | 20.2% |
| 5071140 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.61 | 55.0 | 5.04e-01 | 100.0% | 79.3% |
| 3596809 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.61 | 48.0 | 4.08e-01 | 83.3% | 52.5% |
| 3969687 | 3755.3.1.461 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › MksF | 0.61 | 53.0 | 4.01e-01 | 93.9% | 59.6% |
| 3229124 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.60 | 46.0 | 4.27e-01 | 80.7% | 93.1% |
| 4880662 | 141.1.1.8 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › Terpene_syn_C_2 | 0.60 | 41.0 | 3.06e-01 | 71.9% | 26.9% |
| 4683324 | 101.1.1.26 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › UPF0122 | 0.60 | 43.0 | 4.40e-01 | 74.6% | 100.0% |
| 4034285 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.59 | 49.0 | 4.44e-01 | 86.8% | 67.3% |
| 3283447 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.58 | 52.0 | 4.29e-01 | 96.5% | 75.0% |
| 3177704 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.57 | 40.0 | 3.21e-01 | 100.0% | 36.0% |
| 3179058 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.57 | 49.0 | 4.02e-01 | 93.0% | 78.0% |
| 4533078 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.57 | 50.0 | 4.13e-01 | 95.6% | 80.5% |
| 4055 | 164.1.1.1 ↗ | alpha bundles › Chorismate mutase II › Chorismate mutase II › Chorismate mutase II › CM_2 | 0.56 | 39.0 | 3.43e-01 | 97.4% | 48.5% |
| 5005924 | 3877.1.1.0 ↗ | alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC | 0.54 | 41.0 | 3.53e-01 | 81.6% | 52.1% |
| 3323035 | 5050.1.1.28 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 | 0.54 | 45.0 | 3.67e-01 | 91.2% | 91.8% |
| 3591624 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 44.0 | 3.62e-01 | 92.1% | 90.9% |
| 4034504 | 601.4.1.47 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › MspA_staph | 0.52 | 36.0 | 3.80e-01 | 99.1% | 79.0% |
| 4023478 | 633.10.1.0 ↗ | alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like | 0.51 | 44.0 | 3.73e-01 | 95.6% | 95.8% |