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PH2017_36_ELK_O_B_scaffold_2_prodigal-single.1__X__X__00396
Bact-VirPH2017_36_ELK_O_B_scaffold_2_prodigal-single.1__X__X__00396
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 2-52_138-283
Domain cluster:
rep: BML_08182015_6_5m_scaffold_1_prodigal-single.1__X__X__00377__D34-55_181-308
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2mvzA00 | 2.40.100.10 | Mainly Beta › Beta Barrel › Cyclophilin › Cyclophilin-like | 0.73 | 51.0 | 5.90e-01 | 100.0% | 95.9% |
| 2d7nA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.65 | 18.0 | 2.92e-01 | 100.0% | 58.4% |
| 2pstX00 | 3.90.820.10 | Alpha Beta › Alpha-Beta Complex › Rubredoxin-like › Structural Genomics, Unknown Function 30-nov-00 1gh9 Mol_id | 0.56 | 14.0 | 2.48e-01 | 100.0% | 62.3% |
| 3i6sA03 | 3.50.30.30 | Alpha Beta › 3-Layer(bba) Sandwich › Glucose Oxidase; domain 1 › | 0.50 | 32.0 | 3.86e-01 | 100.0% | 96.9% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3258964 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.70 | 20.0 | 2.98e-01 | 100.0% | 53.3% |
| 4024829 | 75.1.1.1 ↗ | beta barrels › Cyclophilin-like › Cyclophilin-like › Cyclophilin-like › Pro_isomerase | 0.68 | 56.0 | 6.00e-01 | 100.0% | 98.8% |
| 3627438 | 11.1.1.12 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Filamin | 0.63 | 18.0 | 2.69e-01 | 100.0% | 52.2% |
| 3656490 | 75.1.1.1 ↗ | beta barrels › Cyclophilin-like › Cyclophilin-like › Cyclophilin-like › Pro_isomerase | 0.62 | 58.0 | 5.83e-01 | 100.0% | 97.5% |
| 3511950 | 75.1.1.1 ↗ | beta barrels › Cyclophilin-like › Cyclophilin-like › Cyclophilin-like › Pro_isomerase | 0.62 | 53.0 | 5.35e-01 | 100.0% | 90.3% |
| 3507953 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.57 | 19.0 | 3.14e-01 | 100.0% | 81.4% |
| 3939200 | 264.2.1.0 ↗ | beta barrels › LigT-like › Prokaryotic type I DNA topoisomerase beta-barrel domain › Prokaryotic type I DNA topoisomerase beta-barrel domain | 0.51 | 30.0 | 3.68e-01 | 100.0% | 88.5% |
D2
high
residues 57-134
Domain cluster:
representative
CATH (39)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.83 | 57.0 | 5.86e-01 | 71.8% | 96.0% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.73 | 55.0 | 6.19e-01 | 100.0% | 98.4% |
| 3rvyA01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.73 | 49.0 | 4.35e-01 | 70.5% | 77.2% |
| 3e7pA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.73 | 55.0 | 3.81e-01 | 80.8% | 92.5% |
| 1wfdA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.72 | 53.0 | 4.98e-01 | 76.9% | 79.6% |
| 6yz2A01 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.72 | 49.0 | 4.23e-01 | 70.5% | 71.7% |
| 5ffdA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.71 | 64.0 | 5.28e-01 | 100.0% | 78.1% |
| 7qocA01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.71 | 56.0 | 4.23e-01 | 84.6% | 85.0% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.70 | 50.0 | 4.34e-01 | 75.6% | 89.2% |
| 3g36B00 | 1.20.890.10 | Mainly Alpha › Up-down Bundle › cAMP-dependent Protein Kinase, Chain A › cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain | 0.70 | 33.0 | 4.05e-01 | 97.4% | 70.6% |
| 2psmA00 | 1.20.1250.70 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interleukin-15/Interleukin-21 | 0.69 | 61.0 | 5.28e-01 | 100.0% | 63.2% |
| 6a7hA01 | 1.20.140.180 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.69 | 51.0 | 4.33e-01 | 79.5% | 52.3% |
| 1iygA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.68 | 54.0 | 4.44e-01 | 83.3% | 91.0% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 50.0 | 4.65e-01 | 78.2% | 91.8% |
| 3ibpA01 | 1.20.58.850 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 50.0 | 5.19e-01 | 100.0% | 83.3% |
| 2pziB03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.67 | 57.0 | 4.59e-01 | 93.6% | 87.3% |
| 2ehwA00 | 6.10.140.1220 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 55.0 | 4.85e-01 | 91.0% | 81.7% |
| 1kz7A01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.66 | 57.0 | 4.37e-01 | 100.0% | 69.4% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.66 | 48.0 | 4.39e-01 | 76.9% | 73.5% |
| 7e4mA01 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.65 | 53.0 | 3.64e-01 | 88.5% | 86.8% |
| 4an8A02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.64 | 53.0 | 4.65e-01 | 93.6% | 87.7% |
| 2vxgA02 | 1.10.220.100 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › conserved c-terminal region of ge- 1 | 0.64 | 44.0 | 4.35e-01 | 73.1% | 75.3% |
| 3tdoA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.63 | 46.0 | 3.21e-01 | 76.9% | 44.0% |
| 2kc7A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 48.0 | 4.42e-01 | 82.1% | 76.8% |
| 1tj7A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.62 | 46.0 | 4.14e-01 | 78.2% | 77.1% |
| 2go7A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.61 | 43.0 | 4.58e-01 | 74.4% | 89.6% |
| 5j1hA01 | 1.20.58.1060 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 43.0 | 3.36e-01 | 75.6% | 81.9% |
| 3qkyA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.60 | 47.0 | 3.33e-01 | 85.9% | 36.3% |
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.58 | 39.0 | 3.85e-01 | 70.5% | 65.9% |
| 6xpdA01 | 1.20.1510.10 | Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain | 0.57 | 49.0 | 3.72e-01 | 100.0% | 66.3% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.57 | 45.0 | 3.50e-01 | 100.0% | 38.9% |
| 4jgiA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.55 | 43.0 | 4.30e-01 | 85.9% | 88.7% |
| 3s6jE02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.55 | 38.0 | 3.99e-01 | 73.1% | 91.3% |
| 1n81A00 | 1.10.3030.10 | Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 | 0.55 | 48.0 | 3.68e-01 | 100.0% | 55.4% |
| 4s3mB02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.54 | 44.0 | 4.01e-01 | 89.7% | 66.0% |
| 5mj6A04 | 1.25.50.20 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › | 0.54 | 48.0 | 3.17e-01 | 100.0% | 82.8% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.54 | 40.0 | 3.74e-01 | 80.8% | 86.1% |
| 3zbhA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.52 | 47.0 | 4.52e-01 | 98.7% | 93.3% |
| 3n2oA02 | 3.20.20.10 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase | 0.51 | 43.0 | 3.05e-01 | 100.0% | 87.2% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4932775 | 616.1.1.1 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Ribosomal_S15 | 0.93 | 55.0 | 6.05e-01 | 100.0% | 72.3% |
| 3731168 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.86 | 79.0 | 7.10e-01 | 100.0% | 96.2% |
| 3991775 | 3930.1.1.2 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RIG-I_C | 0.86 | 80.0 | 6.17e-01 | 100.0% | 50.6% |
| 3784217 | 5054.1.1.12 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › NCA2 | 0.81 | 75.0 | 5.83e-01 | 100.0% | 54.8% |
| 3798549 | 3930.1.1.2 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RIG-I_C | 0.80 | 74.0 | 5.88e-01 | 100.0% | 54.0% |
| 3498862 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.78 | 55.0 | 4.93e-01 | 73.1% | 80.0% |
| 3485540 | 603.1.1.1 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin | 0.76 | 58.0 | 4.36e-01 | 79.5% | 62.3% |
| 3244235 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.74 | 59.0 | 5.42e-01 | 85.9% | 100.0% |
| 5028461 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.73 | 50.0 | 4.77e-01 | 100.0% | 61.1% |
| 3272953 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.73 | 65.0 | 5.32e-01 | 97.4% | 55.7% |
| 4634281 | 611.4.1.0 ↗ | alpha bundles › N-cbl like › PG0775 C-terminal domain-like › PG0775 C-terminal domain-like | 0.73 | 59.0 | 4.60e-01 | 84.6% | 84.0% |
| 3266427 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.72 | 52.0 | 4.54e-01 | 76.9% | 69.2% |
| 4626953 | 604.5.1.3 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ArAE_1_C | 0.72 | 52.0 | 5.01e-01 | 76.9% | 92.2% |
| 3974602 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.70 | 48.0 | 4.00e-01 | 71.8% | 50.0% |
| 3289474 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.70 | 51.0 | 4.80e-01 | 76.9% | 89.5% |
| 3350920 | 109.4.1.1314 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_1, TPR_8, TPR_11 | 0.70 | 54.0 | 4.37e-01 | 80.8% | 61.4% |
| 3593236 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.70 | 49.0 | 4.38e-01 | 73.1% | 76.4% |
| 5070319 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.70 | 48.0 | 3.86e-01 | 70.5% | 49.7% |
| 3424566 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.69 | 50.0 | 4.86e-01 | 76.9% | 98.8% |
| 3759862 | 605.1.1.118 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › KRAB | 0.68 | 59.0 | 5.49e-01 | 97.4% | 100.0% |
| 3596831 | 1021.1.1.0 ↗ | a+b two layers › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases › C-terminal domain in RNA helicases | 0.68 | 58.0 | 5.96e-01 | 100.0% | 100.0% |
| 3408532 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.67 | 56.0 | 4.17e-01 | 100.0% | 40.0% |
| 3416922 | 109.4.1.1199 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_Nup160_C | 0.67 | 48.0 | 3.42e-01 | 76.9% | 37.1% |
| 5057804 | 109.7.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Cytochrome c oxidase subunit E › Cytochrome c oxidase subunit E | 0.66 | 46.0 | 4.69e-01 | 73.1% | 90.7% |
| 4116357 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.66 | 57.0 | 4.39e-01 | 100.0% | 93.7% |
| 3986989 | 5054.1.1.68 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › AI-2E_transport | 0.64 | 55.0 | 4.39e-01 | 100.0% | 53.5% |
| 3647788 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.64 | 46.0 | 4.27e-01 | 100.0% | 61.1% |
| 3962973 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.63 | 43.0 | 3.61e-01 | 70.5% | 63.0% |
| 5054366 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.63 | 48.0 | 3.89e-01 | 82.1% | 54.7% |
| 3262581 | 4156.1.1.0 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like | 0.63 | 52.0 | 4.11e-01 | 92.3% | 89.7% |
| 3857352 | 592.1.1.8 ↗ | alpha arrays › PWI domain-like › PWI domain › PWI domain › TRI4_N | 0.62 | 51.0 | 5.23e-01 | 100.0% | 97.3% |
| 3470890 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.62 | 35.0 | 3.22e-01 | 100.0% | 41.0% |
| 3695374 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 53.0 | 3.28e-01 | 98.7% | 22.5% |
| 3721382 | 192.29.1.175 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Pkr1 | 0.61 | 45.0 | 4.40e-01 | 100.0% | 71.8% |
| 5077884 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.60 | 44.0 | 4.40e-01 | 79.5% | 97.5% |
| 3343255 | 5.1.4.37 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Nup160 | 0.59 | 44.0 | 2.76e-01 | 83.3% | 90.6% |
| 5040477 | 4163.1.1.1 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 | 0.58 | 45.0 | 3.83e-01 | 82.1% | 65.6% |
| 3220375 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.58 | 44.0 | 3.10e-01 | 83.3% | 46.8% |
| 5052013 | 5059.1.1.1 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA | 0.58 | 49.0 | 3.37e-01 | 98.7% | 84.6% |
| 5045530 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 43.0 | 4.15e-01 | 82.1% | 90.0% |
| 3271988 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.51 | 38.0 | 3.95e-01 | 79.5% | 84.9% |