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PHAGE-A8--js4906-27-3_S30_scaffold_1_curated_closed_complete_prodigal-single.1XX__00112

Bact-Vir

PHAGE-A8--js4906-27-3_S30_scaffold_1_curated_closed_complete_prodigal-single.1__X__X__00112

Identity

Kingdom:: phage

Quality

85.3 mean pLDDT

Cluster

View cluster (2 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 16-29_68-79_97-201

PDB

Domain cluster: rep: IMGVR_UViG_3300026537_000007-3300026537-Ga0209157_100910311__D185-289

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00122.26 best	E1-E2_ATPase	93.0	1.30e-26	76.3%	93.1%

CATH (24)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2hc8A00	2.70.150.10	Mainly Beta › Distorted Sandwich › Calcium-transporting ATPase, cytoplasmic transduction domain A › Calcium-transporting ATPase, cytoplasmic transduction domain A	0.95	70.0	7.56e-01	74.8%	86.7%
6xmpA01	2.70.150.10	Mainly Beta › Distorted Sandwich › Calcium-transporting ATPase, cytoplasmic transduction domain A › Calcium-transporting ATPase, cytoplasmic transduction domain A	0.91	65.0	6.52e-01	73.3%	98.5%
6hrbB01	2.70.150.10	Mainly Beta › Distorted Sandwich › Calcium-transporting ATPase, cytoplasmic transduction domain A › Calcium-transporting ATPase, cytoplasmic transduction domain A	0.87	66.0	7.20e-01	77.9%	97.3%
1su4A01	2.70.150.10	Mainly Beta › Distorted Sandwich › Calcium-transporting ATPase, cytoplasmic transduction domain A › Calcium-transporting ATPase, cytoplasmic transduction domain A	0.81	78.0	7.16e-01	100.0%	82.7%
2zxeA01	2.70.150.10	Mainly Beta › Distorted Sandwich › Calcium-transporting ATPase, cytoplasmic transduction domain A › Calcium-transporting ATPase, cytoplasmic transduction domain A	0.80	78.0	7.06e-01	100.0%	78.9%
7bspA01	2.70.150.10	Mainly Beta › Distorted Sandwich › Calcium-transporting ATPase, cytoplasmic transduction domain A › Calcium-transporting ATPase, cytoplasmic transduction domain A	0.79	67.0	6.28e-01	86.3%	100.0%
2jmzA01	2.170.16.10	Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain	0.59	28.0	2.60e-01	88.5%	35.7%
4qmaA02	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.55	38.0	3.76e-01	71.8%	83.9%
3cewA01	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.55	40.0	4.38e-01	94.7%	91.8%
1dq3A01	2.170.16.10	Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain	0.55	28.0	2.55e-01	88.5%	37.9%
4e2tB00	2.170.16.10	Mainly Beta › Beta Complex › Endonuclease - Pi-scei; Chain A, domain 1 › Hedgehog/Intein (Hint) domain	0.54	29.0	2.68e-01	89.3%	40.2%
3h7jA02	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.53	40.0	4.30e-01	94.7%	92.7%
4xvhA01	2.60.120.260	Mainly Beta › Sandwich › Jelly Rolls › Galactose-binding domain-like	0.53	40.0	4.41e-01	89.3%	98.1%
1uijB01	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.52	43.0	4.01e-01	91.6%	69.7%
3fjsC00	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.52	39.0	4.28e-01	87.8%	95.3%
5fljA00	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.52	45.0	4.01e-01	93.1%	67.0%
6voxA02	2.60.40.420	Mainly Beta › Sandwich › Immunoglobulin-like › Cupredoxins - blue copper proteins	0.51	38.0	4.10e-01	87.8%	91.1%
2xu9A03	2.60.40.420	Mainly Beta › Sandwich › Immunoglobulin-like › Cupredoxins - blue copper proteins	0.51	37.0	3.75e-01	85.5%	76.6%
3h8uA00	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.51	42.0	4.41e-01	96.9%	95.9%
1fi2A00	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.51	42.0	3.64e-01	88.5%	74.6%
4lejA02	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.51	44.0	4.01e-01	92.4%	71.6%
2pytA00	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.51	42.0	4.32e-01	95.4%	92.2%
3gydA00	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.50	43.0	3.84e-01	90.1%	76.4%
1rc6A00	2.60.120.10	Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls	0.50	44.0	3.62e-01	100.0%	52.1%

ECOD (99)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3588008	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.99	81.0	8.02e-01	99.2%	80.7%
5073687	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.97	69.0	8.18e-01	72.5%	100.0%
3173354	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.96	71.0	7.02e-01	74.8%	99.3%
3363568	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.96	81.0	7.62e-01	100.0%	75.3%
4231542	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.96	93.0	5.55e-01	100.0%	25.1%
4943938	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.96	70.0	7.36e-01	74.8%	81.7%
4981497	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.95	70.0	7.51e-01	74.8%	85.2%
3973056	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.95	70.0	7.35e-01	74.8%	82.5%
3602828	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.95	93.0	5.96e-01	100.0%	38.0%
3969485	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.95	69.0	7.59e-01	74.0%	91.8%
3964323	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.95	70.0	7.50e-01	74.8%	85.2%
4538625	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.95	70.0	8.02e-01	74.8%	98.0%
3587995	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.95	70.0	7.31e-01	74.8%	82.5%
3466195	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.95	92.0	5.65e-01	100.0%	31.6%
3710856	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.95	69.0	7.28e-01	74.8%	81.7%
4944497	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.94	69.0	7.26e-01	74.8%	81.7%
3943275	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.94	69.0	7.26e-01	74.8%	81.7%
4012086	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.94	69.0	6.98e-01	74.8%	96.9%
3632554	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.94	69.0	6.63e-01	74.8%	88.3%
3723096	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.94	67.0	7.02e-01	72.5%	90.0%
4960483	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.94	81.0	7.73e-01	100.0%	79.3%
None	—		0.94	80.0	8.12e-01	100.0%	88.5%
3258917	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.94	69.0	6.71e-01	74.8%	84.3%
3971963	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.94	69.0	7.36e-01	74.8%	85.2%
4014393	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.94	69.0	7.20e-01	74.8%	85.8%
3182131	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.93	68.0	6.96e-01	74.8%	81.2%
5024838	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.93	68.0	7.48e-01	74.8%	89.1%
4975608	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.93	68.0	7.65e-01	74.8%	93.3%
5072740	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.93	68.0	7.46e-01	74.8%	89.1%
3786710	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.93	68.0	6.66e-01	74.8%	89.3%
3291022	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.93	68.0	7.05e-01	75.6%	86.4%
4278363	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.93	68.0	7.11e-01	74.8%	81.7%
5053448	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.92	68.0	7.74e-01	74.8%	98.0%
4299722	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.92	67.0	7.08e-01	74.8%	82.5%
4944371	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.92	67.0	7.30e-01	74.0%	89.1%
None	—		0.92	89.0	5.62e-01	100.0%	33.1%
3203941	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.92	67.0	6.91e-01	74.8%	92.0%
3311919	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.92	67.0	7.04e-01	74.8%	90.8%
3594890	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.92	88.0	5.57e-01	100.0%	33.9%
3176887	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.92	88.0	5.46e-01	100.0%	33.7%
5073408	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.92	72.0	7.53e-01	80.2%	97.5%
3386756	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.91	67.0	7.38e-01	75.6%	90.0%
3681739	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.91	83.0	7.56e-01	100.0%	74.5%
3373565	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.91	65.0	7.15e-01	74.8%	87.3%
4991483	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.91	65.0	6.92e-01	74.8%	82.6%
5001404	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.91	69.0	7.07e-01	77.1%	80.8%
3590113	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.91	66.0	7.59e-01	74.8%	99.0%
3956948	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.91	67.0	7.18e-01	75.6%	93.0%
3423323	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.91	72.0	7.43e-01	100.0%	85.6%
3386533	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.91	67.0	7.04e-01	75.6%	83.3%
3596742	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.90	82.0	7.88e-01	100.0%	84.1%
4953535	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.90	66.0	6.91e-01	74.8%	82.5%
3685779	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.90	85.0	8.13e-01	100.0%	87.6%
2921156	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.90	65.0	6.55e-01	74.8%	85.7%
4129350	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.90	65.0	7.16e-01	74.8%	89.1%
3318148	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.90	73.0	7.66e-01	98.5%	91.7%
3954914	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.89	70.0	7.06e-01	80.2%	90.8%
4315226	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.89	83.0	7.60e-01	100.0%	78.1%
3987877	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.89	65.0	7.43e-01	74.8%	98.0%
3279165	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.89	83.0	8.06e-01	100.0%	90.0%
5017326	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.88	69.0	7.24e-01	80.2%	87.5%
3741380	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.88	80.0	6.93e-01	100.0%	65.9%
3457967	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.88	69.0	6.71e-01	80.2%	90.0%
5016894	5073.1.1.11 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_C	0.87	84.0	5.39e-01	100.0%	37.4%
3716059	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.87	84.0	5.31e-01	100.0%	33.6%
3643370	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.87	78.0	7.27e-01	100.0%	78.1%
4383358	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.87	83.0	5.22e-01	100.0%	32.4%
3641113	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.86	79.0	4.96e-01	96.9%	35.9%
None	—		0.86	83.0	7.22e-01	100.0%	78.4%
4021786	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.86	83.0	7.13e-01	100.0%	73.7%
3590666	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.86	83.0	7.19e-01	100.0%	75.1%
4362560	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.86	83.0	7.83e-01	100.0%	93.3%
5052803	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.85	83.0	7.24e-01	100.0%	77.2%
4959618	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.85	83.0	7.71e-01	100.0%	91.0%
5002958	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.85	82.0	7.22e-01	100.0%	77.2%
5046799	10.13.1.10 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › Cation_ATPase_C	0.85	81.0	5.14e-01	100.0%	37.4%
4963870	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.84	62.0	6.52e-01	75.6%	90.8%
3624764	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.84	79.0	6.95e-01	100.0%	70.6%
None	—		0.84	81.0	7.12e-01	100.0%	75.6%
3173571	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.84	81.0	6.96e-01	100.0%	75.8%
3466582	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.84	79.0	6.96e-01	100.0%	71.7%
5048270	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.84	81.0	7.36e-01	100.0%	81.8%
3638557	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.84	81.0	6.74e-01	100.0%	66.8%
5083437	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.82	78.0	7.41e-01	97.7%	85.3%
3325752	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.82	78.0	6.75e-01	100.0%	69.7%
3248844	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.82	80.0	7.78e-01	100.0%	95.0%
5002094	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.82	79.0	7.28e-01	100.0%	83.7%
3451862	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.82	78.0	6.33e-01	100.0%	88.4%
3707240	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.81	79.0	6.99e-01	100.0%	75.4%
4029517	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.81	79.0	6.98e-01	100.0%	83.4%
3313939	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.81	78.0	6.76e-01	100.0%	71.9%
3275653	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.81	78.0	6.63e-01	100.0%	73.3%
4049756	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.81	78.0	7.28e-01	100.0%	91.6%
3590834	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.81	78.0	4.90e-01	100.0%	35.9%
3685567	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.80	77.0	6.24e-01	100.0%	64.0%
3258532	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.80	77.0	6.45e-01	100.0%	86.3%
3711760	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.80	76.0	6.87e-01	100.0%	88.8%
4025395	10.13.1.1 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A › E1-E2_ATPase	0.79	76.0	7.03e-01	100.0%	89.4%
3596894	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.78	75.0	6.34e-01	100.0%	78.5%

D2 high residues 277-312_488-591

PDB

Domain cluster: representative

Pfam (2)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00702.33 best	Hydrolase	26.9	8.60e-06	60.7%	28.8%
PF08282.19	Hydrolase_3	28.3	2.10e-06	42.1%	20.8%

CATH (87)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2zxeA03	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.91	68.0	6.25e-01	76.4%	100.0%
5ksdA03	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.87	64.0	6.18e-01	75.0%	100.0%
7bsqA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.86	74.0	6.20e-01	88.6%	98.2%
2iyeA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.77	72.0	6.86e-01	97.1%	94.9%
4dw8A01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.71	55.0	5.28e-01	80.0%	97.5%
2qyhB01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.71	55.0	5.30e-01	80.0%	95.5%
2p9jB00	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.70	58.0	5.47e-01	85.0%	93.8%
5is2A03	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.70	54.0	4.57e-01	80.0%	91.8%
1nf2A01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.70	54.0	5.15e-01	80.0%	94.4%
3m1yC01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.70	54.0	5.32e-01	80.0%	95.9%
3dnpA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.70	54.0	5.08e-01	79.3%	93.8%
1k1eD00	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.69	55.0	5.08e-01	81.4%	86.5%
1l6rA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.69	53.0	5.10e-01	79.3%	96.8%
4qjbB01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.69	53.0	5.10e-01	80.0%	96.9%
3ewiB00	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.69	53.0	5.09e-01	80.0%	91.1%
2b30A01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.68	58.0	5.32e-01	88.6%	95.4%
1wr8A01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.68	53.0	5.03e-01	80.0%	94.4%
3fzqB01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.68	53.0	5.13e-01	80.7%	95.5%
3umoA00	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.68	52.0	4.04e-01	80.0%	83.5%
1rlmA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.68	53.0	5.03e-01	80.0%	92.6%
3mmzC00	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.68	57.0	5.38e-01	86.4%	93.8%
3e8mA00	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.68	55.0	5.15e-01	82.9%	89.6%
3n28A01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.68	54.0	5.27e-01	82.9%	92.9%
3ie7A00	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.68	52.0	4.00e-01	79.3%	82.2%
2abqA00	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.68	51.0	3.97e-01	78.6%	90.2%
3daoB01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.68	52.0	5.05e-01	80.7%	96.8%
2nwhA00	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.67	51.0	3.99e-01	80.0%	83.1%
4ezeB00	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.67	63.0	4.89e-01	100.0%	97.2%
3pgvB01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.67	51.0	4.91e-01	79.3%	95.6%
1nrwA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.67	52.0	5.02e-01	80.0%	77.3%
4navA00	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.67	61.0	5.54e-01	95.7%	87.8%
3fvvA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.66	50.0	4.90e-01	77.1%	99.3%
2ajrA01	3.40.1190.20	Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase	0.66	50.0	4.05e-01	78.6%	88.7%
1rkuA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.66	46.0	5.17e-01	80.0%	90.1%
3gygC01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.65	50.0	4.47e-01	80.0%	87.3%
2q09A02	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.64	47.0	3.71e-01	77.1%	94.6%
2b8eB01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.64	51.0	5.41e-01	82.1%	95.2%
2zosB01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.63	48.0	4.61e-01	79.3%	96.9%
4hgnB00	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.63	57.0	5.40e-01	95.7%	93.3%
3e0lA02	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.62	45.0	3.56e-01	76.4%	96.1%
2qs8A02	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.61	48.0	3.71e-01	81.4%	75.2%
2p9bA03	3.40.50.10910	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Amidohydrolase	0.61	43.0	4.56e-01	72.1%	100.0%
2l82A00	3.40.50.11230	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.61	46.0	4.44e-01	80.0%	99.4%
3r4cA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.59	56.0	5.23e-01	100.0%	96.4%
4ap9A01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.59	45.0	4.57e-01	79.3%	92.1%
3abiA01	3.40.50.720	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain	0.58	45.0	4.18e-01	80.0%	74.4%
3bf0C01	3.90.226.10	Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1	0.58	43.0	3.85e-01	78.6%	87.2%
8gr2A01	3.40.50.1110	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase	0.57	43.0	3.85e-01	78.6%	99.5%
4beqA02	3.20.20.10	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase	0.56	40.0	3.51e-01	72.9%	86.6%
3ke3A02	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.56	48.0	3.97e-01	94.3%	76.8%
5ot1A02	3.20.20.80	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases	0.55	44.0	3.36e-01	86.4%	85.7%
1jndA01	3.20.20.80	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases	0.55	48.0	3.75e-01	95.0%	97.7%
6w6aA00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.55	42.0	3.53e-01	80.7%	79.9%
1jcmP00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.55	44.0	3.60e-01	85.0%	68.3%
3r89A00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.55	44.0	3.52e-01	85.7%	76.1%
4ritA02	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.55	47.0	4.05e-01	96.4%	95.3%
3o63A00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.55	44.0	3.82e-01	85.7%	78.0%
3op7A02	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.54	46.0	4.07e-01	94.3%	90.7%
4obvA02	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.54	47.0	3.94e-01	94.3%	84.5%
6cblD01	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.54	46.0	4.05e-01	95.0%	73.7%
4c5yA02	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.54	48.0	3.73e-01	98.6%	84.9%
6yhhA02	3.20.20.80	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases	0.54	46.0	3.54e-01	95.7%	83.1%
3kwsA00	3.20.20.150	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes	0.54	45.0	3.73e-01	92.9%	89.1%
6n2aB02	3.20.20.10	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Alanine racemase	0.54	38.0	3.28e-01	73.6%	76.4%
2p10C01	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.54	47.0	4.00e-01	98.6%	94.3%
2r8cA02	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.54	46.0	3.64e-01	95.7%	86.9%
2jgqA00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.53	42.0	3.66e-01	85.7%	91.3%
3dugA02	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.53	47.0	3.67e-01	95.7%	85.7%
6jebA02	3.20.20.80	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases	0.53	46.0	3.47e-01	95.7%	85.0%
7mpyA01	3.20.20.20	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Dihydropteroate synthase-like	0.53	40.0	3.40e-01	80.0%	75.0%
7lldA01	3.40.640.10	Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain)	0.53	45.0	3.90e-01	95.7%	68.5%
4ovxA00	3.20.20.150	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes	0.53	46.0	3.74e-01	94.3%	94.4%
1g6cB00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.53	43.0	3.71e-01	87.1%	75.2%
1xi3A00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.53	41.0	3.70e-01	82.9%	75.7%
3u80A00	3.40.50.9100	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dehydroquinase, class II	0.53	40.0	4.20e-01	79.3%	90.6%
2w7tA00	3.40.50.880	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain	0.53	40.0	3.25e-01	79.3%	90.9%
1kcxA02	3.20.20.140	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases	0.53	46.0	3.36e-01	94.3%	86.1%
1vr6A02	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.52	46.0	3.74e-01	97.9%	71.3%
5wq5A01	3.40.50.1970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.52	44.0	4.25e-01	92.9%	93.1%
3uhjC01	3.40.50.1970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.52	44.0	4.32e-01	92.9%	93.4%
2v4uA00	3.40.50.880	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain	0.52	39.0	3.21e-01	80.0%	91.0%
4kqcA01	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.51	39.0	3.76e-01	80.0%	73.0%
4gp6A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.51	43.0	4.03e-01	90.7%	97.1%
1ta9B01	3.40.50.1970	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold ›	0.50	42.0	4.17e-01	92.9%	97.4%
6bmaA00	3.20.20.70	Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I	0.50	44.0	3.67e-01	99.3%	78.4%
4zjpA02	3.40.50.2300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator	0.50	42.0	4.16e-01	90.7%	92.4%
1pzxB01	3.40.50.10440	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dihydroxyacetone kinase; domain 1	0.50	38.0	4.07e-01	79.3%	93.4%

ECOD (100)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3590934	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.99	80.0	7.77e-01	82.1%	100.0%
3374450	5073.1.1.11 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_C	0.94	91.0	6.10e-01	100.0%	41.1%
3643840	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.93	84.0	6.95e-01	92.9%	100.0%
3984046	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.93	90.0	7.51e-01	100.0%	81.4%
3628512	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.93	90.0	7.62e-01	100.0%	86.7%
3973545	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.93	74.0	7.12e-01	81.4%	100.0%
None	—		0.93	90.0	5.70e-01	100.0%	32.8%
3950149	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.93	90.0	7.35e-01	100.0%	77.8%
5072119	5073.1.1.11 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_C	0.93	90.0	5.64e-01	100.0%	34.1%
3873302	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.93	89.0	5.39e-01	100.0%	24.8%
4113348	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.93	80.0	7.28e-01	88.6%	94.3%
4084610	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.93	90.0	7.74e-01	100.0%	89.0%
5062824	5073.1.1.11 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_C	0.92	89.0	5.62e-01	100.0%	30.9%
3913742	2006.1.1.11 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3	0.92	80.0	7.05e-01	89.3%	96.3%
4944684	2006.1.1.77 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Cation_ATPase_C	0.92	78.0	7.21e-01	87.1%	100.0%
4231542	10.13.1.0 ↗	beta sandwiches › jelly-roll › Calcium ATPase, transduction domain A › Calcium ATPase, transduction domain A	0.92	89.0	5.41e-01	100.0%	25.8%
3191556	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.92	89.0	7.07e-01	100.0%	86.4%
3687833	5073.1.1.18 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Hydrolase	0.92	89.0	5.56e-01	100.0%	30.6%
4943049	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.92	70.0	6.82e-01	77.9%	100.0%
5073936	5073.1.1.11 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_C	0.92	88.0	5.57e-01	100.0%	34.7%
5074381	5073.1.1.11 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_C	0.92	88.0	5.56e-01	100.0%	29.7%
3609014	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.92	73.0	5.96e-01	81.4%	97.4%
3638556	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.91	80.0	6.67e-01	89.3%	91.2%
4015627	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.91	78.0	6.87e-01	87.9%	94.7%
4951699	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.91	88.0	7.19e-01	100.0%	77.4%
3361297	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.91	88.0	7.44e-01	100.0%	90.5%
3435483	5073.1.1.5 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_N	0.91	88.0	5.51e-01	100.0%	30.3%
4947522	2006.1.1.11 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3	0.91	71.0	6.94e-01	80.0%	100.0%
3369036	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.91	88.0	7.44e-01	100.0%	88.1%
4959843	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.91	88.0	7.43e-01	100.0%	90.0%
5073689	5073.1.1.11 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_C	0.91	87.0	5.61e-01	100.0%	32.6%
3208620	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.91	68.0	6.53e-01	76.4%	93.5%
4976890	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.91	87.0	5.26e-01	100.0%	51.1%
4862822	2006.1.1.11 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3	0.91	66.0	6.39e-01	74.3%	74.5%
3451861	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.91	87.0	7.22e-01	100.0%	84.0%
3707241	2006.1.1.11 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3	0.91	73.0	6.71e-01	82.1%	91.8%
3397823	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.91	72.0	6.56e-01	81.4%	98.3%
3596739	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.91	87.0	7.21e-01	100.0%	91.1%
3271932	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.90	72.0	6.48e-01	81.4%	88.9%
3955796	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.90	71.0	6.74e-01	80.7%	100.0%
3782342	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.90	76.0	6.85e-01	86.4%	100.0%
4946769	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.90	77.0	7.20e-01	87.9%	100.0%
4971236	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.90	86.0	5.46e-01	100.0%	31.9%
5002097	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.90	65.0	6.55e-01	73.6%	100.0%
3643369	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.90	77.0	7.23e-01	88.6%	100.0%
4025176	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.90	67.0	5.69e-01	76.4%	100.0%
3815730	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.90	64.0	6.34e-01	72.9%	100.0%
3576081	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.89	85.0	5.35e-01	100.0%	38.1%
3399697	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.89	69.0	6.01e-01	79.3%	92.8%
3479682	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.88	66.0	6.15e-01	76.4%	100.0%
3592803	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.88	67.0	5.29e-01	78.6%	92.7%
3958035	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.88	68.0	6.68e-01	80.0%	82.7%
4960486	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.88	75.0	7.29e-01	87.9%	100.0%
3381598	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.88	61.0	6.18e-01	71.4%	100.0%
4322616	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.87	64.0	5.27e-01	75.0%	100.0%
3495460	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.87	67.0	5.74e-01	79.3%	78.6%
2761309	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.87	68.0	6.14e-01	79.3%	83.7%
4049776	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.87	68.0	5.93e-01	80.0%	94.9%
3449818	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.87	58.0	6.75e-01	78.6%	90.5%
3743318	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.87	68.0	5.79e-01	80.7%	100.0%
3247264	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.87	67.0	5.79e-01	80.0%	100.0%
4030297	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.87	68.0	5.75e-01	80.0%	97.1%
3992132	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.86	67.0	5.53e-01	80.0%	100.0%
3719486	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.86	58.0	4.61e-01	79.3%	38.0%
5080047	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.85	60.0	4.40e-01	71.4%	33.9%
5083752	2006.1.1.11 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3	0.85	63.0	6.97e-01	76.4%	100.0%
5069226	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.84	63.0	4.58e-01	77.1%	34.5%
3723376	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.82	80.0	6.75e-01	100.0%	81.0%
3192575	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.82	80.0	6.61e-01	100.0%	90.5%
3631208	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.82	80.0	6.85e-01	100.0%	89.0%
4097333	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.82	79.0	7.35e-01	98.6%	90.3%
3408318	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.82	80.0	6.44e-01	100.0%	66.8%
4215543	5073.1.3.4 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Potassium-transporting ATPase subunit KdpB transmembrane domain › Hydrolase	0.81	79.0	5.28e-01	100.0%	34.9%
4559948	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.81	79.0	6.57e-01	100.0%	74.4%
3973042	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.81	78.0	6.46e-01	99.3%	68.6%
4981498	5073.1.2.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain	0.81	78.0	5.01e-01	100.0%	51.1%
4047441	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.80	77.0	7.24e-01	97.9%	93.1%
3934495	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.80	62.0	5.67e-01	79.3%	100.0%
3819806	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.80	78.0	6.59e-01	100.0%	74.8%
3634107	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.80	69.0	6.34e-01	87.9%	89.4%
4117789	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.80	78.0	6.51e-01	100.0%	71.2%
3839871	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.80	77.0	6.68e-01	100.0%	77.0%
5024841	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.80	77.0	7.01e-01	99.3%	85.1%
5072741	5073.1.2.23 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain › Hydrolase	0.80	77.0	4.96e-01	100.0%	51.4%
4572529	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.79	77.0	6.46e-01	100.0%	72.0%
4116048	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.79	77.0	6.69e-01	100.0%	82.1%
3920532	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.79	77.0	6.24e-01	100.0%	68.1%
3387973	2006.1.1.2 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.79	71.0	6.93e-01	92.1%	92.7%
4943941	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.79	75.0	6.71e-01	98.6%	81.1%
3987876	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.78	69.0	6.61e-01	90.0%	91.6%
3386531	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.78	75.0	6.67e-01	98.6%	79.5%
4975349	5073.1.2.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain	0.78	74.0	5.14e-01	100.0%	35.8%
4993174	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.77	74.0	5.08e-01	100.0%	37.0%
3965531	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.77	75.0	6.76e-01	100.0%	85.6%
4974326	5073.1.2.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain	0.77	74.0	5.05e-01	100.0%	38.6%
4944500	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.77	74.0	6.33e-01	100.0%	76.1%
4988136	5073.1.2.23 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain › Hydrolase	0.76	73.0	4.96e-01	100.0%	36.3%
3604272	2006.1.1.1 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase	0.76	59.0	5.77e-01	80.0%	87.3%
5001405	5073.1.2.23 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain › Hydrolase	0.75	72.0	5.03e-01	100.0%	40.0%
4974196	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.72	61.0	6.28e-01	88.6%	100.0%

D3 high residues 318-458

PDB

Domain cluster: representative

CATH (12)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3ar4A04	3.40.1110.10	Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N	0.85	80.0	6.47e-01	98.6%	100.0%
6psyA01	3.40.50.1000	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like	0.83	75.0	6.25e-01	95.0%	100.0%
6zhhA01	3.40.1110.10	Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N	0.82	74.0	6.72e-01	95.0%	100.0%
3gwiA00	3.40.1110.10	Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N	0.81	74.0	7.03e-01	97.2%	100.0%
6xmtA02	3.40.1110.10	Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N	0.79	71.0	6.67e-01	95.0%	100.0%
5ksdA04	3.40.1110.10	Alpha Beta › 3-Layer(aba) Sandwich › Calcium-transporting ATPase, cytoplasmic domain N › Calcium-transporting ATPase, cytoplasmic domain N	0.79	71.0	7.03e-01	95.7%	100.0%
4jhnD00	2.130.10.30	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	0.55	40.0	2.98e-01	75.9%	37.2%
1cf9A01	2.40.180.10	Mainly Beta › Beta Barrel › Catalase HpII, Chain A, domain 1 › Catalase core domain	0.53	49.0	3.54e-01	100.0%	85.0%
2yxdA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.52	40.0	3.73e-01	80.1%	95.5%
1l3iA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.51	39.0	3.65e-01	81.6%	95.7%
8eg0B01	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.51	35.0	2.62e-01	76.6%	28.0%
8f5pE01	2.130.10.10	Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase	0.51	37.0	2.68e-01	75.2%	36.6%

ECOD (57)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3588009	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.94	87.0	8.93e-01	99.3%	99.3%
3590045	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.90	83.0	8.50e-01	96.5%	100.0%
3961593	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.89	86.0	8.14e-01	100.0%	95.6%
4019720	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.86	68.0	7.53e-01	97.2%	100.0%
4197656	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.85	70.0	7.63e-01	98.6%	100.0%
5058875	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.85	67.0	7.45e-01	94.3%	100.0%
4026368	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.85	78.0	6.67e-01	97.2%	100.0%
3325367	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.85	77.0	6.47e-01	95.0%	100.0%
4979783	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.84	66.0	7.33e-01	93.6%	100.0%
5016893	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.84	77.0	7.57e-01	97.2%	100.0%
3957677	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.84	66.0	7.28e-01	97.2%	100.0%
3960063	267.1.1.2 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Hydrolase	0.83	71.0	7.25e-01	100.0%	91.9%
4976890	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.83	79.0	4.82e-01	100.0%	26.8%
3410227	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.83	79.0	6.63e-01	100.0%	99.5%
3694970	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.83	77.0	6.44e-01	97.9%	100.0%
3971964	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.83	70.0	7.43e-01	100.0%	99.2%
3973109	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.83	68.0	7.32e-01	97.9%	100.0%
4943940	267.1.1.2 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Hydrolase	0.83	70.0	7.49e-01	99.3%	100.0%
4062246	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.83	70.0	7.41e-01	100.0%	99.2%
4947520	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.83	77.0	7.35e-01	98.6%	100.0%
5068674	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.83	77.0	6.69e-01	97.9%	100.0%
5052804	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.82	77.0	6.51e-01	97.9%	100.0%
3973546	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.82	75.0	7.11e-01	96.5%	100.0%
5034231	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.82	78.0	6.86e-01	100.0%	99.5%
3280036	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.82	67.0	7.30e-01	95.7%	100.0%
4219495	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.82	76.0	6.66e-01	97.9%	100.0%
4663703	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.82	76.0	6.55e-01	97.9%	99.5%
3961640	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.82	76.0	6.37e-01	100.0%	61.3%
3310240	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.82	78.0	6.78e-01	100.0%	99.5%
4937913	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.82	67.0	7.26e-01	97.2%	100.0%
3957479	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.82	77.0	5.08e-01	100.0%	39.8%
4998676	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.82	76.0	6.55e-01	97.9%	100.0%
4981498	5073.1.2.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain	0.81	71.0	4.62e-01	100.0%	23.8%
3265510	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.81	73.0	6.61e-01	95.7%	100.0%
5046144	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.81	76.0	6.60e-01	98.6%	100.0%
4966659	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.81	71.0	5.62e-01	100.0%	49.6%
4953425	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.81	76.0	7.17e-01	99.3%	100.0%
3177523	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.81	74.0	6.46e-01	96.5%	100.0%
4943047	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.81	74.0	6.31e-01	97.2%	100.0%
5073409	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.80	73.0	6.35e-01	96.5%	100.0%
3964321	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.80	65.0	7.02e-01	99.3%	99.2%
3580620	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.80	64.0	5.88e-01	83.0%	98.9%
4967080	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.80	75.0	6.48e-01	99.3%	100.0%
3963322	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.80	63.0	6.97e-01	95.7%	100.0%
4959828	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.79	67.0	7.13e-01	95.0%	100.0%
3278166	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.79	72.0	6.77e-01	95.7%	100.0%
3636014	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.79	74.0	7.18e-01	100.0%	98.1%
3604238	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.78	71.0	7.28e-01	95.0%	100.0%
5065686	267.1.1.3 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Cation_ATPase	0.78	70.0	6.42e-01	95.7%	100.0%
4338163	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.77	67.0	7.04e-01	95.7%	100.0%
4028547	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.76	70.0	6.28e-01	95.7%	100.0%
4299595	267.1.1.0 ↗	a+b complex topology › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain › Metal cation-transporting ATPase, ATP-binding domain	0.74	70.0	6.67e-01	100.0%	99.4%
3226497	145.1.1.1 ↗	alpha arrays › F-box domain › F-box domain › F-box domain › F-box	0.55	34.0	3.75e-01	88.7%	74.8%
4986411	2003.1.5.179 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636	0.54	42.0	3.75e-01	81.6%	90.4%
3751241	3775.1.1.1 ↗	beta barrels › Lysosome membrane protein 2 lumenal domain › Lysosome membrane protein 2 lumenal domain › Lysosome membrane protein 2 lumenal domain › CD36	0.53	48.0	3.55e-01	99.3%	94.5%
3525883	3775.1.1.1 ↗	beta barrels › Lysosome membrane protein 2 lumenal domain › Lysosome membrane protein 2 lumenal domain › Lysosome membrane protein 2 lumenal domain › CD36	0.52	47.0	3.38e-01	97.9%	89.6%
1903993	2003.1.5.179 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636	0.52	40.0	3.73e-01	80.9%	95.0%

D4 high residues 602-828

PDB

Domain cluster: representative

CATH (16)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2d9dA00	1.20.58.120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain	0.67	23.0	3.71e-01	76.2%	79.8%
4p9tA01	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.61	27.0	3.63e-01	74.0%	76.7%
3t6gB00	1.20.120.230	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like	0.59	27.0	3.44e-01	84.1%	70.9%
2clbA01	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.58	37.0	4.28e-01	83.7%	89.3%
3b9wA00	1.10.3430.10	Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains	0.58	52.0	4.42e-01	96.5%	85.4%
3t9jA00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.56	35.0	4.25e-01	83.7%	97.9%
2jbwA01	1.20.1440.110	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase	0.56	21.0	3.05e-01	86.3%	72.8%
2w9zA01	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.54	29.0	3.71e-01	84.1%	86.5%
2uvaG01	1.20.1050.120	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.53	30.0	3.70e-01	85.9%	88.2%
2wbiB03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.51	31.0	3.64e-01	71.8%	84.2%
2pg0A03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.51	31.0	3.67e-01	72.7%	87.9%
1rx0A03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.51	31.0	3.62e-01	71.4%	85.2%
3lomA00	1.10.600.10	Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase	0.51	39.0	3.61e-01	78.9%	67.7%
2jswA00	1.20.1410.10	Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain	0.51	39.0	4.18e-01	85.9%	94.7%
2jbyA00	1.10.437.10	Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like	0.51	21.0	2.78e-01	85.0%	66.1%
1r0dA00	1.20.1410.10	Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain	0.50	39.0	4.15e-01	84.6%	93.3%

ECOD (19)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3590903	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.91	76.0	6.29e-01	100.0%	53.2%
3590230	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.88	73.0	6.17e-01	99.6%	55.7%
4185887	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.86	71.0	5.86e-01	96.0%	52.2%
4523647	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.80	70.0	5.78e-01	97.4%	54.9%
4599579	5073.1.1.11 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › Cation_ATPase_C	0.71	64.0	5.09e-01	97.8%	50.6%
3663356	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.70	63.0	4.36e-01	94.7%	30.6%
3500011	5073.1.1.0 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M	0.70	63.0	4.91e-01	94.7%	47.3%
3801602	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.70	63.0	5.09e-01	95.2%	53.0%
3318905	2006.1.1.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like	0.68	62.0	4.74e-01	96.5%	44.0%
3454448	5073.1.2.7 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain › PhoLip_ATPase_C	0.68	62.0	6.02e-01	96.5%	89.0%
3994891	5073.1.1.7 ↗	alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M › PhoLip_ATPase_C	0.68	63.0	4.99e-01	98.2%	53.3%
4941161	1075.5.1.2 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ	0.55	39.0	3.82e-01	72.2%	92.8%
5028169	1075.5.1.2 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ	0.54	38.0	3.76e-01	71.4%	91.6%
3293516	4953.1.1.23 ↗	beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › YIF1	0.54	36.0	3.86e-01	80.2%	75.0%
3800846	5059.1.1.0 ↗	alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter	0.52	41.0	3.61e-01	82.4%	64.6%
5022995	5067.1.1.4 ↗	alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL	0.52	38.0	4.13e-01	89.4%	90.3%
5058985	7064.1.1.1 ↗	alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1	0.51	35.0	4.13e-01	70.0%	98.1%
4955441	1075.5.1.1 ↗	alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE	0.51	35.0	3.51e-01	73.1%	67.0%
3799013	304.28.1.9 ↗	a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › Patched	0.50	38.0	2.71e-01	84.1%	26.0%

D5 medium residues 80-96_223-276

PDB

Domain cluster: representative

CATH (25)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4m70B00	1.10.246.200	Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › WPP domain	0.66	52.0	4.80e-01	93.0%	67.0%
1fioA00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.64	46.0	3.39e-01	76.1%	43.2%
2i0mA01	1.20.58.220	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2	0.63	45.0	3.97e-01	76.1%	51.9%
3tulB00	1.20.120.330	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2	0.61	44.0	3.63e-01	76.1%	84.2%
4i1mB01	1.20.120.1700	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.61	45.0	3.74e-01	76.1%	49.6%
3nbxX03	1.20.58.1510	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.61	43.0	3.88e-01	76.1%	58.4%
3hr0B01	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.60	43.0	4.23e-01	76.1%	75.9%
1vw4L01	3.90.1030.10	Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › Ribosomal protein L17	0.59	43.0	3.45e-01	76.1%	60.7%
3fppA03	6.10.140.1990	Special › Helix non-globular › Helix Hairpins ›	0.59	40.0	3.79e-01	71.8%	93.2%
2b5uA02	1.10.287.620	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins	0.58	42.0	3.20e-01	76.1%	50.3%
1y6xA00	1.10.287.1080	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like	0.58	38.0	3.62e-01	71.8%	55.2%
1u00A02	1.20.1270.10	Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 ›	0.58	41.0	3.76e-01	76.1%	59.4%
1ydxA02	1.10.287.1120	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein	0.57	38.0	3.59e-01	76.1%	54.4%
2r9iA00	1.10.287.80	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain	0.57	39.0	3.98e-01	73.2%	80.3%
3anwA01	1.20.58.1030	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.57	41.0	3.57e-01	76.1%	47.8%
3umcD02	1.10.150.240	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2	0.57	39.0	3.84e-01	90.1%	66.7%
2p4vA01	1.10.287.180	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain	0.57	41.0	4.01e-01	76.1%	73.7%
2ic6A00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.56	40.0	4.05e-01	76.1%	84.5%
4l0rB00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.56	40.0	3.96e-01	74.6%	91.8%
3lphC00	6.10.140.630	Special › Helix non-globular › Helix Hairpins ›	0.55	38.0	4.07e-01	76.1%	87.9%
1b5lA00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.53	44.0	3.42e-01	90.1%	98.0%
1z0pA00	1.20.58.90	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.52	37.0	3.72e-01	76.1%	75.3%
3mhsB00	1.10.246.140	Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › ENY2/SUS1	0.51	45.0	4.21e-01	100.0%	86.8%
1chuA03	1.20.58.100	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain	0.51	35.0	3.34e-01	71.8%	58.0%
1grjA01	1.10.287.180	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain	0.50	39.0	3.91e-01	88.7%	97.3%

ECOD (41)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4991390	5058.1.1.16 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1	0.80	59.0	5.33e-01	77.5%	88.4%
4624818	621.1.1.0 ↗	alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	0.76	52.0	4.81e-01	74.6%	56.7%
4540106	3396.1.1.3 ↗	extended segments › HIG1 domain family member 1A › HIG1 domain family member 1A › HIG1 domain family member 1A › DUF4481	0.75	54.0	5.23e-01	76.1%	73.8%
4964984	5058.1.1.0 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region	0.74	53.0	4.78e-01	76.1%	56.0%
2984622	3396.1.1.1 ↗	extended segments › HIG1 domain family member 1A › HIG1 domain family member 1A › HIG1 domain family member 1A › HIG_1_N	0.74	54.0	5.51e-01	76.1%	81.2%
4547274	3714.1.1.0 ↗	a+b two layers › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain	0.73	53.0	4.71e-01	76.1%	55.0%
3516948	5076.1.1.1 ↗	alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr	0.73	65.0	4.30e-01	97.2%	36.0%
5065662	5058.1.1.0 ↗	alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region	0.73	52.0	5.32e-01	76.1%	77.1%
2622460	3396.1.1.1 ↗	extended segments › HIG1 domain family member 1A › HIG1 domain family member 1A › HIG1 domain family member 1A › HIG_1_N	0.70	50.0	5.09e-01	76.1%	81.4%
3262801	3788.1.1.0 ↗	alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr)	0.70	50.0	4.15e-01	76.1%	44.0%
3495807	4177.1.1.0 ↗	alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like	0.69	49.0	3.36e-01	76.1%	44.3%
3839281	5043.1.1.0 ↗	extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like	0.66	47.0	4.51e-01	74.6%	70.0%
3761374	3826.1.1.36 ↗	alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Mito_carr	0.66	54.0	4.54e-01	91.5%	74.0%
3389798	2006.1.4.0 ↗	a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like	0.63	51.0	5.17e-01	88.7%	100.0%
3414399	5086.1.1.106 ↗	alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF725	0.63	51.0	3.96e-01	93.0%	84.7%
4039421	3710.1.1.1 ↗	alpha bundles › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › Golgi to ER traffic protein 1 cytosolic domain › CHD5	0.63	45.0	4.03e-01	76.1%	87.0%
3412574	3291.1.1.82 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING	0.63	45.0	3.71e-01	76.1%	78.5%
3258488	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.63	44.0	3.98e-01	74.6%	95.0%
3701873	191.1.1.0 ↗	alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain	0.62	43.0	3.75e-01	73.2%	51.8%
5002748	605.1.1.1 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA	0.60	43.0	4.26e-01	76.1%	78.7%
3749862	605.1.1.178 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › TMEM215	0.59	40.0	4.32e-01	70.4%	93.3%
3991225	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.59	42.0	3.88e-01	74.6%	60.0%
3503444	192.8.1.0 ↗	alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain	0.59	41.0	3.90e-01	76.1%	65.6%
3297770	622.4.1.26 ↗	alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › HisKA	0.58	41.0	3.91e-01	76.1%	65.9%
5055921	604.12.1.0 ↗	alpha bundles › Spectrin repeat-like › MIT domain › MIT domain	0.57	38.0	3.68e-01	73.2%	61.3%
4521514	605.1.1.0 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase	0.57	40.0	4.02e-01	76.1%	86.7%
5066415	4323.1.1.0 ↗	alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C	0.56	40.0	3.14e-01	76.1%	38.2%
3627448	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.56	40.0	3.52e-01	76.1%	51.8%
3884035	611.2.1.0 ↗	alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl)	0.56	40.0	3.34e-01	76.1%	44.8%
3296414	192.29.1.168 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF641	0.56	39.0	4.01e-01	76.1%	78.6%
3634896	622.4.1.0 ↗	alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related	0.55	40.0	3.40e-01	76.1%	56.5%
3949413	3755.3.1.0 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin	0.55	39.0	3.22e-01	76.1%	74.8%
3201680	192.17.1.1 ↗	alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like › Rbsn	0.55	39.0	3.68e-01	76.1%	62.5%
4937862	3291.1.1.0 ↗	alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related	0.54	45.0	4.00e-01	97.2%	87.3%
5042020	192.2.1.0 ↗	alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin	0.54	40.0	3.66e-01	76.1%	63.3%
3672993	150.5.1.6 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › DUF3082	0.54	47.0	4.08e-01	100.0%	71.3%
4930709	3877.1.1.0 ↗	alpha bundles › Membrane protein insertase YidC-related › Membrane protein insertase YidC-related › Membrane protein insertase YidC	0.53	46.0	3.42e-01	100.0%	63.6%
4219465	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.53	37.0	3.32e-01	76.1%	61.8%
3560590	3755.3.1.142 ↗	alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › FAM186A-B_C	0.52	45.0	3.60e-01	100.0%	88.0%
4041347	192.7.1.2 ↗	alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N	0.51	36.0	3.19e-01	76.1%	52.7%
4016635	3922.1.1.0 ↗	alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3	0.50	41.0	3.73e-01	93.0%	100.0%