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PHAGE-A8--js4906-27-3_S30_scaffold_1_curated_closed_complete_prodigal-single.1__X__X__00267

Bact-Vir

PHAGE-A8--js4906-27-3_S30_scaffold_1_curated_closed_complete_prodigal-single.1__X__X__00267

Identity

Kingdom:
phage

Quality

86.5 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 80-202
PDB
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3w1eA03 2.40.10.410 Mainly Beta › Beta Barrel › Thrombin, subunit H › FlgT, C-terminal domain 0.53 33.0 3.81e-01 89.4% 85.4%
6nvxB02 2.30.120.10 Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region 0.53 24.0 2.94e-01 91.9% 64.9%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5010503 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.58 36.0 4.02e-01 93.5% 78.9%
3729636 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.55 38.0 3.06e-01 70.7% 83.0%
D2 medium residues 1-55_242-275
PDB
Domain cluster: representative
CATH (60)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3tbiB02 6.10.140.1670 Special › Helix non-globular › Helix Hairpins › 0.83 63.0 6.09e-01 79.8% 100.0%
2m6uA00 1.20.81.20 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › 0.82 51.0 5.32e-01 88.8% 68.3%
7dluA01 1.10.287.1260 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 57.0 5.42e-01 94.4% 67.6%
2uv8A07 6.10.140.1410 Special › Helix non-globular › Helix Hairpins › 0.75 63.0 6.45e-01 97.8% 92.9%
2vkzA02 3.40.47.10 Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase 0.75 63.0 4.39e-01 97.8% 30.2%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.72 51.0 5.73e-01 73.0% 97.1%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.72 51.0 4.93e-01 74.2% 82.4%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.71 58.0 4.86e-01 87.6% 85.0%
3mekA04 1.25.40.970 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.69 36.0 3.78e-01 91.0% 55.0%
3cwzB01 1.20.58.900 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RUN domain 0.69 45.0 3.80e-01 83.1% 41.1%
2mpkA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.67 41.0 4.46e-01 82.0% 73.0%
1wncB00 1.20.5.300 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.67 52.0 5.45e-01 96.6% 90.1%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.66 51.0 4.99e-01 80.9% 75.5%
1k04A02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.66 46.0 4.42e-01 73.0% 76.0%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.66 46.0 4.05e-01 78.7% 51.2%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.65 51.0 4.92e-01 91.0% 72.8%
2ra1A03 1.20.58.770 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 30.0 3.48e-01 76.4% 60.3%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.64 57.0 5.82e-01 95.5% 100.0%
1cxzB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.64 47.0 4.85e-01 77.5% 81.4%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.64 45.0 4.75e-01 86.5% 80.2%
1a7eA00 1.20.120.50 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like 0.63 39.0 3.57e-01 76.4% 46.6%
6tqfA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.63 49.0 3.26e-01 85.4% 52.9%
3fppA03 6.10.140.1990 Special › Helix non-globular › Helix Hairpins › 0.63 49.0 4.94e-01 82.0% 81.8%
1dkxA02 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 41.0 4.39e-01 87.6% 75.0%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.63 47.0 4.44e-01 79.8% 71.8%
2dw4A03 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.62 52.0 4.96e-01 87.6% 88.1%
2c2aA01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.62 49.0 4.96e-01 84.3% 96.7%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.61 40.0 4.77e-01 76.4% 98.3%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.61 40.0 3.87e-01 76.4% 60.8%
7e84A03 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 45.0 4.13e-01 80.9% 89.4%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 43.0 4.52e-01 95.5% 83.5%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.60 43.0 4.60e-01 77.5% 93.6%
3k17A02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.59 41.0 3.54e-01 86.5% 45.7%
1ma1A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.59 41.0 4.79e-01 74.2% 100.0%
1bgfA00 1.10.532.10 Mainly Alpha › Orthogonal Bundle › Transcription Factor, Stat-4 › STAT transcription factor, N-terminal domain 0.59 39.0 3.43e-01 73.0% 48.4%
2i0mA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.58 43.0 4.08e-01 82.0% 65.1%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.58 48.0 4.57e-01 88.8% 81.1%
5i1uA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.58 44.0 3.11e-01 83.1% 27.7%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.58 37.0 3.69e-01 76.4% 62.4%
1yq3C02 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.58 45.0 4.23e-01 97.8% 68.5%
1ulyA02 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.57 47.0 4.51e-01 89.9% 79.2%
8b6jF01 1.10.287.20 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Ubiquinol-cytochrome C reductase hinge domain 0.57 41.0 4.55e-01 77.5% 100.0%
4dxwA02 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 48.0 4.48e-01 93.3% 94.6%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 50.0 4.09e-01 95.5% 86.8%
3layF00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.56 45.0 4.75e-01 94.4% 97.4%
2optA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 47.0 3.99e-01 91.0% 63.9%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.55 48.0 4.50e-01 93.3% 84.1%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.55 47.0 3.88e-01 91.0% 92.2%
2p7vA00 1.20.120.1370 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 0.55 46.0 3.89e-01 92.1% 90.7%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.55 44.0 4.55e-01 95.5% 93.9%
2hxoA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 45.0 3.83e-01 88.8% 59.7%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 43.0 3.65e-01 86.5% 82.0%
1h7cA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 48.0 4.60e-01 97.8% 87.4%
4akgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.53 41.0 3.40e-01 84.3% 56.5%
4fppB01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.53 39.0 4.28e-01 95.5% 98.6%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.53 45.0 4.57e-01 94.4% 94.4%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 44.0 4.10e-01 87.6% 87.9%
1gqeA01 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.52 37.0 3.49e-01 84.3% 60.2%
3vkgA02 1.20.140.100 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain 0.51 41.0 3.45e-01 86.5% 56.5%
3ls1A00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.51 43.0 3.78e-01 93.3% 91.7%
ECOD (56)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4034278 5043.1.1.0 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like 0.90 59.0 7.21e-01 79.8% 100.0%
5063536 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.82 61.0 5.85e-01 93.3% 69.0%
5056477 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.82 62.0 6.23e-01 92.1% 78.9%
4940986 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.79 65.0 6.32e-01 96.6% 80.0%
4547274 3714.1.1.0 a+b two layers › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain › Lon-like protease MtaLonC helical domain 0.79 60.0 5.75e-01 93.3% 71.0%
4027216 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.78 52.0 4.91e-01 80.9% 58.1%
4324592 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.78 63.0 6.09e-01 95.5% 77.0%
4964387 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.77 66.0 6.31e-01 94.4% 79.0%
3285146 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.76 64.0 6.73e-01 93.3% 100.0%
3598977 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.76 66.0 6.73e-01 98.9% 96.5%
4942625 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.76 56.0 5.88e-01 76.4% 90.0%
4951918 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.76 62.0 6.06e-01 94.4% 82.1%
5018642 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.75 62.0 5.85e-01 94.4% 75.2%
4029754 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.74 53.0 5.43e-01 73.0% 96.5%
3756047 192.29.1.243 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Fy-3 0.74 56.0 5.62e-01 80.9% 96.7%
5043090 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.73 50.0 5.30e-01 71.9% 80.0%
3717860 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.72 54.0 5.42e-01 79.8% 83.3%
3398929 5041.1.1.32 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › TMEM141 0.72 63.0 6.28e-01 94.4% 93.3%
5009433 5042.1.1.1 extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › CorA 0.71 49.0 5.64e-01 76.4% 98.5%
3397641 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.71 45.0 3.71e-01 78.7% 35.6%
4940500 5058.1.1.16 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 0.70 59.0 5.40e-01 93.3% 69.6%
3821344 5076.1.1.1 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.70 59.0 4.08e-01 93.3% 49.8%
3563120 3914.1.1.4 alpha bundles › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMEM16 lipid scramblase transmembrane domain › TMC 0.70 55.0 3.44e-01 93.3% 15.8%
4400622 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.70 61.0 5.84e-01 98.9% 82.9%
5050114 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.70 49.0 4.97e-01 75.3% 73.3%
4564044 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.69 57.0 4.07e-01 89.9% 31.5%
4937585 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.69 56.0 5.29e-01 92.1% 73.3%
4950709 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 45.0 5.24e-01 85.4% 92.3%
3957435 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.69 58.0 5.25e-01 96.6% 68.3%
3948970 5058.1.1.2 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st 0.69 51.0 4.79e-01 83.1% 63.6%
3965106 605.1.1.4 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.68 53.0 5.63e-01 96.6% 100.0%
4121314 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.68 55.0 5.41e-01 92.1% 83.2%
3412574 3291.1.1.82 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › ING 0.67 53.0 4.66e-01 84.3% 77.7%
4514462 547.1.1.1 alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer 0.67 57.0 5.52e-01 96.6% 84.0%
3832264 2004.1.1.184 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 0.67 51.0 3.14e-01 79.8% 17.1%
3832044 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.66 48.0 4.40e-01 75.3% 90.4%
4025638 1189.1.1.0 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor 0.66 56.0 4.29e-01 97.8% 41.5%
3237980 2003.1.2.18 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.64 54.0 3.28e-01 92.1% 80.3%
3712635 5069.1.3.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits 0.64 48.0 4.71e-01 78.7% 77.9%
3164951 5094.1.1.1 a+b duplicates or obligate multimers › OmpH-like › OmpH-like › OmpH-like › OmpH 0.64 54.0 4.39e-01 93.3% 59.4%
4142346 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.64 50.0 4.66e-01 83.1% 75.5%
3963355 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.63 45.0 4.81e-01 73.0% 88.0%
3787585 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.63 52.0 4.93e-01 87.6% 78.1%
3932320 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.63 52.0 4.43e-01 93.3% 56.4%
3184140 5086.1.1.87 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › ING 0.62 53.0 4.82e-01 91.0% 73.9%
4964878 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.62 47.0 5.21e-01 87.6% 100.0%
3836427 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.62 51.0 4.91e-01 91.0% 78.0%
5053066 192.7.1.0 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm 0.61 50.0 3.61e-01 91.0% 32.8%
5021415 3579.1.1.33 extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › PsiE 0.61 46.0 4.11e-01 89.9% 56.8%
3600869 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.60 49.0 4.56e-01 89.9% 80.0%
3264065 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.59 47.0 4.98e-01 91.0% 95.0%
3297770 622.4.1.26 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › HisKA 0.59 47.0 4.83e-01 91.0% 89.4%
3233589 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.58 43.0 4.66e-01 86.5% 90.7%
4876531 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.58 50.0 3.93e-01 94.4% 60.8%
5035200 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.56 44.0 4.73e-01 92.1% 98.7%
4613072 101.1.2.721 alpha arrays › HTH › HTH › winged helix domain › MarR_2, PF27113 0.55 47.0 3.82e-01 93.3% 80.6%
D3 medium residues 56-79_206-241
PDB
Domain cluster: representative
CATH (34)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1vbfA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.63 49.0 3.39e-01 88.3% 24.6%
3nwsA01 2.40.50.800 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.62 47.0 3.64e-01 85.0% 90.8%
1l0wA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.60 46.0 3.88e-01 85.0% 92.5%
2z3zA01 2.140.10.30 Mainly Beta › 8 Propeller › Methanol Dehydrogenase; Chain A › Dipeptidylpeptidase IV, N-terminal domain 0.59 50.0 3.10e-01 100.0% 39.8%
2bklA02 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.59 50.0 3.21e-01 100.0% 38.8%
2gnxA02 3.30.450.240 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.58 45.0 3.76e-01 93.3% 47.7%
1yr2A02 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.57 48.0 3.07e-01 98.3% 31.7%
1nrvA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.57 49.0 4.20e-01 100.0% 72.0%
4hkqA04 3.10.20.370 Alpha Beta › Roll › Ubiquitin-like (UB roll) › 0.57 39.0 3.67e-01 73.3% 82.9%
4gniA03 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.56 41.0 3.68e-01 78.3% 55.2%
1k32A02 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.56 45.0 2.87e-01 93.3% 34.0%
1h9oA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.56 48.0 4.05e-01 100.0% 64.8%
2xp1A01 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.56 46.0 4.12e-01 100.0% 71.6%
2oq1A03 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.56 47.0 4.10e-01 100.0% 72.0%
1u6zA02 3.30.420.150 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Exopolyphosphatase. Domain 2 0.56 45.0 3.29e-01 93.3% 88.3%
3iujA02 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.56 46.0 2.95e-01 96.7% 30.3%
5hsqA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.55 39.0 3.22e-01 88.3% 37.2%
1wquA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.53 44.0 3.73e-01 100.0% 57.9%
2ix2B00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.52 37.0 2.50e-01 75.0% 31.4%
6qk7A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.52 43.0 2.78e-01 100.0% 37.5%
3w9kA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.52 36.0 2.82e-01 73.3% 40.7%
2retA00 3.30.1300.30 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like 0.52 36.0 3.29e-01 73.3% 71.4%
1vr8A00 3.40.1000.20 Alpha Beta › 3-Layer(aba) Sandwich › Protein Transport Mog1p; Chain A › TM1622-like 0.52 35.0 2.83e-01 95.0% 31.9%
4oevA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.52 42.0 3.30e-01 100.0% 92.9%
3hrgA02 3.30.420.260 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Protein of unknown function DUF3822, C-terminal domain 0.51 39.0 3.30e-01 88.3% 46.5%
1iv0A00 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.51 35.0 3.12e-01 75.0% 46.9%
2a1vA00 3.90.1150.30 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.51 36.0 2.80e-01 75.0% 63.8%
1t6cA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.51 36.0 2.98e-01 76.7% 56.0%
1p9rA01 3.30.450.90 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.51 35.0 2.95e-01 80.0% 38.7%
1xocA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.51 37.0 2.92e-01 100.0% 32.3%
4r80A00 3.10.450.630 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 34.0 3.26e-01 71.7% 90.8%
5zg8A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.50 37.0 3.29e-01 85.0% 93.1%
1stzA03 3.30.390.60 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Heat-inducible transcription repressor hrca homolog; domain 3 0.50 36.0 3.24e-01 78.3% 82.0%
3hi0A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.50 35.0 2.95e-01 76.7% 56.4%
ECOD (39)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4891041 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.64 45.0 3.43e-01 80.0% 30.0%
5057701 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.61 48.0 3.80e-01 90.0% 85.9%
5044036 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.60 48.0 3.76e-01 90.0% 85.2%
3962456 7059.1.1.0 a+b complex topology › SatS C-terminal domain › SatS C-terminal domain › SatS C-terminal domain 0.59 42.0 3.08e-01 78.3% 26.7%
3665105 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.59 45.0 3.99e-01 85.0% 71.1%
4030408 2003.1.5.4 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PCMT 0.58 45.0 3.14e-01 90.0% 25.0%
3847020 5.1.5.75 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40, ANAPC4_WD40 0.58 46.0 2.95e-01 95.0% 30.4%
3677760 2004.1.1.162 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Rad51 0.57 44.0 2.92e-01 86.7% 79.9%
3905730 214.1.1.1 a+b two layers › SH2 › SH2 › SH2 › SH2 0.57 48.0 4.00e-01 100.0% 57.4%
3598894 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.56 46.0 2.98e-01 95.0% 64.1%
3777778 214.1.1.1 a+b two layers › SH2 › SH2 › SH2 › SH2 0.56 48.0 3.22e-01 100.0% 28.6%
3788879 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.56 45.0 2.79e-01 95.0% 68.3%
3618546 214.1.1.1 a+b two layers › SH2 › SH2 › SH2 › SH2 0.56 46.0 3.88e-01 100.0% 60.9%
3935139 214.1.1.1 a+b two layers › SH2 › SH2 › SH2 › SH2 0.55 46.0 3.62e-01 100.0% 49.0%
4994059 2492.1.1.2 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › JAB 0.55 40.0 3.21e-01 81.7% 42.2%
3715664 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.55 37.0 2.95e-01 71.7% 66.9%
3477642 214.1.1.1 a+b two layers › SH2 › SH2 › SH2 › SH2 0.54 45.0 3.75e-01 100.0% 83.3%
3742540 5.1.5.88 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › Nucleoporin_N 0.54 43.0 2.67e-01 95.0% 33.6%
3382115 226.1.1.20 a+b two layers › POZ domain › POZ domain › POZ domain › PF30468, PF30469 0.54 38.0 2.74e-01 75.0% 41.6%
3890372 214.1.1.1 a+b two layers › SH2 › SH2 › SH2 › SH2 0.54 44.0 3.80e-01 100.0% 67.3%
2724185 4091.1.1.1 beta complex topology › L,D-transpeptidase catalytic domain-like › L,D-transpeptidase catalytic domain-like › L,D-transpeptidase catalytic domain-like › YkuD 0.54 44.0 3.35e-01 95.0% 84.0%
3509348 214.1.1.15 a+b two layers › SH2 › SH2 › SH2 › DUF7063, DUF7145 0.54 45.0 2.94e-01 100.0% 26.0%
3506772 214.1.1.10 a+b two layers › SH2 › SH2 › SH2 › DUF7145 0.54 44.0 3.65e-01 100.0% 61.6%
4029656 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.54 37.0 3.04e-01 75.0% 53.6%
3477283 214.1.1.1 a+b two layers › SH2 › SH2 › SH2 › SH2 0.54 43.0 3.86e-01 100.0% 70.0%
3546025 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.53 40.0 3.16e-01 83.3% 77.8%
4991801 2492.1.1.18 a+b three layers › Cytidine deaminase-like › Cytidine deaminase-like › Cytidine deaminase-like › Prok-JAB 0.53 41.0 3.35e-01 100.0% 42.4%
3483784 214.1.1.1 a+b two layers › SH2 › SH2 › SH2 › SH2 0.53 44.0 3.80e-01 100.0% 67.6%
4838661 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.53 40.0 3.46e-01 93.3% 48.6%
3500244 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.53 43.0 2.73e-01 96.7% 34.7%
3809440 226.1.1.20 a+b two layers › POZ domain › POZ domain › POZ domain › PF30468, PF30469 0.53 38.0 3.08e-01 78.3% 64.0%
3221112 389.1.2.1 few secondary structure elements › EGF-like › EGF-related › Complement control module/SCR domain › Sushi 0.53 37.0 3.77e-01 80.0% 76.7%
3492079 214.1.1.1 a+b two layers › SH2 › SH2 › SH2 › SH2 0.52 42.0 3.78e-01 100.0% 68.0%
3604467 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.52 43.0 3.08e-01 100.0% 44.8%
3040602 2484.1.1.2 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin 0.52 37.0 3.15e-01 78.3% 73.6%
3517650 214.1.1.10 a+b two layers › SH2 › SH2 › SH2 › DUF7145 0.51 42.0 3.68e-01 100.0% 71.0%
4036210 220.1.1.36 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_12 0.50 40.0 2.95e-01 96.7% 52.7%
4032095 6043.1.1.6 a+b two layers › yfeY-like › yfeY-like › yfeY-like › PF28288 0.50 33.0 3.13e-01 80.0% 54.7%
4606510 4263.2.1.0 a+b two layers › TTHA1528-like › FtsH Periplasmic Domain › FtsH Periplasmic Domain 0.50 37.0 3.40e-01 83.3% 95.3%