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Papain-like_cysteine_peptidase

Euk-Vir

Pandoravirus_macleodensis

Papain-like_cysteine_peptidase__YP_009481341__Pandoravirus_macleodensis__2107707

Identity

Accession:
YP_009481341 ↗
Protein ID:
Papain-like_cysteine_peptidase
Kingdom:
euk

Quality

47.7 mean pLDDT

Taxonomy

TaxID: 2107707

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 258-288_317-424_447-478
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00112.30 best Peptidase_C1 20.9 4.80e-04 88.9% 16.4%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5fpwA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.56 54.0 4.39e-01 100.0% 84.9%
3oisB00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.56 53.0 4.48e-01 100.0% 94.0%
1x42A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.53 26.0 3.42e-01 93.0% 89.2%
5cqgA03 1.10.10.2210 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.52 24.0 3.30e-01 87.7% 88.6%
1deuB00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.52 49.0 4.19e-01 100.0% 93.5%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3250297 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.60 55.0 4.58e-01 96.5% 87.1%
3723538 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.58 54.0 4.37e-01 100.0% 63.9%
3564430 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.56 53.0 4.22e-01 99.4% 85.9%
4448672 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.56 53.0 4.25e-01 100.0% 78.9%
3617140 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.55 52.0 4.18e-01 100.0% 78.4%
None 0.55 52.0 4.04e-01 100.0% 72.6%
5016484 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.54 51.0 4.09e-01 100.0% 81.9%
3906939 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.53 50.0 4.04e-01 100.0% 80.0%
4978305 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.52 49.0 3.98e-01 100.0% 86.4%
3510485 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.51 49.0 3.85e-01 100.0% 80.0%
3520437 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.50 26.0 2.52e-01 80.7% 44.2%
D2 medium residues 289-316_479-613_648-681
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00112.30 best Peptidase_C1 70.9 2.40e-19 55.3% 44.1%
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5fpwA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.82 58.0 4.91e-01 71.1% 79.8%
1xkgA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.80 57.0 4.82e-01 72.1% 73.8%
1deuB00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.79 56.0 4.96e-01 71.1% 94.6%
3oisB00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.76 54.0 4.78e-01 71.6% 89.5%
3pnrA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.76 53.0 4.94e-01 71.1% 95.0%
3iutA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.74 52.0 5.06e-01 71.1% 100.0%
1act000 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.74 52.0 5.06e-01 72.1% 100.0%
1jqpA02 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.69 55.0 5.23e-01 81.7% 100.0%
2wbfX00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.68 56.0 4.97e-01 83.8% 99.6%
5egwA00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.66 56.0 4.42e-01 86.8% 62.0%
3pw3D00 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.65 48.0 3.87e-01 75.1% 98.6%
1gcbA01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.64 48.0 3.69e-01 76.1% 95.5%
4k7cA01 3.90.70.10 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases 0.62 47.0 3.66e-01 76.6% 96.4%
4mi7A00 3.90.70.170 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.54 30.0 3.83e-01 78.7% 89.5%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3261680 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.86 60.0 5.16e-01 71.1% 79.6%
3244679 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.86 59.0 4.61e-01 70.1% 76.5%
3250297 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.85 60.0 5.21e-01 72.1% 85.4%
3395889 219.1.1.2 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1,Propeptide_C1 0.85 59.0 4.87e-01 71.1% 80.6%
3479869 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.85 60.0 4.91e-01 72.1% 80.6%
4377695 219.1.1.2 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1,Propeptide_C1 0.84 58.0 4.81e-01 70.1% 80.6%
3242975 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.84 60.0 4.80e-01 72.1% 74.4%
4000671 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.83 57.0 5.11e-01 70.1% 80.0%
3497089 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.83 58.0 4.87e-01 71.1% 79.0%
3486878 219.1.1.110 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1, Peptidase_C1_2 0.83 58.0 4.81e-01 71.1% 76.8%
2793930 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.83 59.0 4.89e-01 72.1% 81.5%
3514380 219.1.1.110 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1, Peptidase_C1_2 0.82 58.0 4.87e-01 71.6% 80.3%
3906939 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.82 58.0 4.90e-01 72.1% 77.4%
3514367 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.82 57.0 5.00e-01 71.1% 88.4%
3481577 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.80 56.0 5.15e-01 70.6% 91.7%
3891882 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.80 56.0 4.81e-01 71.1% 86.7%
3795430 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.79 55.0 5.04e-01 70.1% 88.1%
3993778 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.79 55.0 5.02e-01 70.1% 80.0%
3674165 219.1.1.110 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1, Peptidase_C1_2 0.79 55.0 4.83e-01 70.1% 85.6%
3776905 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.79 57.0 5.07e-01 72.6% 91.5%
3470973 219.1.1.110 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1, Peptidase_C1_2 0.79 55.0 5.02e-01 70.1% 89.8%
4974486 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.79 57.0 4.84e-01 72.6% 81.0%
3391656 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.79 55.0 4.63e-01 71.1% 74.8%
3488949 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.79 54.0 5.07e-01 70.1% 91.9%
None 0.79 54.0 4.56e-01 70.1% 71.5%
3745990 219.1.1.110 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1, Peptidase_C1_2 0.79 54.0 5.05e-01 70.1% 94.5%
4053732 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.79 54.0 4.52e-01 70.1% 69.4%
3865831 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.78 56.0 4.61e-01 72.6% 73.8%
3273778 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.78 54.0 4.45e-01 70.1% 71.3%
3791026 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.78 56.0 4.59e-01 72.1% 72.2%
3798944 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.78 55.0 4.97e-01 70.6% 90.8%
4026925 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.78 55.0 4.66e-01 72.1% 93.2%
3421122 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.78 56.0 5.06e-01 72.6% 91.6%
4448672 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.78 54.0 4.52e-01 70.1% 72.7%
3807595 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.77 53.0 4.31e-01 70.1% 65.0%
3705335 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.77 56.0 5.01e-01 73.6% 92.3%
3248099 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.77 53.0 4.37e-01 70.1% 70.7%
3884055 219.1.1.110 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1, Peptidase_C1_2 0.77 55.0 5.03e-01 72.6% 87.5%
3443485 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.77 55.0 4.38e-01 72.6% 68.3%
4391291 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.77 55.0 5.06e-01 72.1% 93.8%
4127832 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.77 55.0 4.62e-01 72.1% 75.0%
3668220 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.77 53.0 4.52e-01 70.1% 75.5%
None 0.76 54.0 4.44e-01 72.6% 69.4%
3836765 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.76 53.0 4.92e-01 70.1% 90.6%
3998812 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.75 63.0 5.07e-01 86.3% 78.8%
3699843 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.74 55.0 4.64e-01 76.1% 73.2%
4059449 219.1.1.110 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1, Peptidase_C1_2 0.74 53.0 4.71e-01 72.6% 83.5%
5032667 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.73 59.0 4.88e-01 83.2% 80.0%
5064725 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.72 53.0 4.52e-01 74.1% 78.8%
3229331 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.71 58.0 5.31e-01 82.7% 92.6%
4663619 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.71 58.0 4.75e-01 83.8% 84.3%
3216614 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.70 57.0 4.67e-01 83.2% 76.9%
4030613 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.69 56.0 4.95e-01 82.2% 98.1%
3317119 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.69 56.0 5.12e-01 83.8% 92.0%
4415790 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.69 56.0 4.85e-01 83.8% 98.6%
4029993 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.68 56.0 4.26e-01 84.3% 71.6%
3433434 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.67 51.0 4.98e-01 78.2% 97.2%
None 0.67 55.0 4.42e-01 83.8% 67.9%
4268173 219.1.1.0 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases 0.66 56.0 4.40e-01 86.8% 61.6%
3354341 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.64 45.0 4.21e-01 72.1% 79.6%
3331216 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.62 43.0 4.99e-01 75.1% 94.0%
3710887 219.1.1.1 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1 0.57 47.0 4.68e-01 84.3% 95.1%
4123449 4.8.1.35 beta barrels › SH3 › Chromo domain-like › Chromo domain-like › DUF1292 0.56 23.0 3.44e-01 74.6% 88.2%
3717955 219.1.1.4 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C2 0.53 39.0 3.22e-01 75.6% 81.4%