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Phosphohydrolase
Euk-VirPandoravirus_dulcis
Phosphohydrolase__YP_008318586__Pandoravirus_dulcis__1349409
Identity
- Accession:
- YP_008318586 ↗
- Protein ID:
- Phosphohydrolase
- Kingdom:
- euk
Quality
81.9
mean pLDDT
Cluster
View cluster (7 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 89-149_234-307_369-388
Domain cluster:
rep: FN667788.1__CBJ93864.1__CPT_0055__00055__D7-157
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01966.29 best | HD | 42.7 | 9.10e-11 | 65.2% | 58.6% |
D2
medium
residues 150-189_206-233
Domain cluster:
representative
CATH (53)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.93 | 82.0 | 6.92e-01 | 92.6% | 98.1% |
| 2zdiB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.91 | 86.0 | 7.24e-01 | 100.0% | 91.5% |
| 1x4tA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.91 | 68.0 | 7.37e-01 | 77.9% | 100.0% |
| 1zpyA00 | 6.10.140.1960 | Special › Helix non-globular › Helix Hairpins › | 0.89 | 72.0 | 6.43e-01 | 85.3% | 69.2% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.89 | 70.0 | 7.35e-01 | 82.4% | 96.8% |
| 2gd5A00 | 6.10.140.1230 | Special › Helix non-globular › Helix Hairpins › | 0.89 | 81.0 | 6.16e-01 | 97.1% | 53.5% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.89 | 77.0 | 7.48e-01 | 91.2% | 94.5% |
| 3vkgA12 | 1.10.287.2610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.88 | 81.0 | 5.55e-01 | 100.0% | 57.2% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.88 | 69.0 | 6.00e-01 | 83.8% | 85.0% |
| 1cxzB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.87 | 81.0 | 7.40e-01 | 98.5% | 86.0% |
| 3a8pA02 | 6.10.140.680 | Special › Helix non-globular › Helix Hairpins › | 0.87 | 79.0 | 6.44e-01 | 95.6% | 61.4% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.87 | 75.0 | 6.56e-01 | 91.2% | 75.8% |
| 2xzmO02 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.87 | 63.0 | 6.28e-01 | 75.0% | 77.1% |
| 3aeiA00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.87 | 70.0 | 6.18e-01 | 85.3% | 100.0% |
| 6v9zA02 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.85 | 77.0 | 4.77e-01 | 95.6% | 37.5% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.85 | 75.0 | 7.22e-01 | 94.1% | 90.7% |
| 2rp4A00 | 6.10.280.60 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Transcription factor p53, C-terminal domain | 0.85 | 59.0 | 5.86e-01 | 72.1% | 69.0% |
| 2dw4A03 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.84 | 78.0 | 6.73e-01 | 100.0% | 84.2% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.84 | 79.0 | 5.98e-01 | 100.0% | 51.0% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.84 | 78.0 | 7.02e-01 | 100.0% | 86.7% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.84 | 77.0 | 7.23e-01 | 98.5% | 86.4% |
| 4abxA02 | 6.10.140.1090 | Special › Helix non-globular › Helix Hairpins › | 0.83 | 71.0 | 6.46e-01 | 91.2% | 77.0% |
| 1skvA00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.82 | 72.0 | 7.43e-01 | 97.1% | 96.9% |
| 1sg2A00 | 3.30.910.20 | Alpha Beta › 2-Layer Sandwich › Protein Binding, DinI Protein; Chain A › Skp domain | 0.81 | 68.0 | 5.19e-01 | 88.2% | 48.9% |
| 2fb5A01 | 1.10.287.770 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like | 0.80 | 69.0 | 6.76e-01 | 92.6% | 94.4% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 71.0 | 6.08e-01 | 98.5% | 89.7% |
| 3zgxA02 | 6.10.140.1720 | Special › Helix non-globular › Helix Hairpins › | 0.80 | 71.0 | 6.41e-01 | 97.1% | 83.5% |
| 1t7sA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.80 | 71.0 | 5.65e-01 | 97.1% | 51.9% |
| 3hr0B01 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.79 | 69.0 | 6.60e-01 | 97.1% | 89.9% |
| 4l8jA04 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.79 | 63.0 | 6.74e-01 | 86.8% | 100.0% |
| 1w99A01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.78 | 67.0 | 5.02e-01 | 97.1% | 46.2% |
| 3pjaJ01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.78 | 68.0 | 5.41e-01 | 95.6% | 63.4% |
| 2lw1A00 | 1.10.287.380 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain | 0.78 | 67.0 | 6.25e-01 | 95.6% | 89.4% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.77 | 68.0 | 6.22e-01 | 97.1% | 76.1% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.77 | 67.0 | 6.44e-01 | 94.1% | 85.7% |
| 4h63K00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.76 | 64.0 | 5.63e-01 | 95.6% | 63.3% |
| 1vf7A03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.76 | 61.0 | 6.43e-01 | 86.8% | 100.0% |
| 1fxkB00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.75 | 64.0 | 5.54e-01 | 97.1% | 93.6% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.74 | 63.0 | 5.80e-01 | 100.0% | 98.9% |
| 1h7cA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 64.0 | 5.68e-01 | 100.0% | 72.8% |
| 4mrsA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.74 | 65.0 | 4.15e-01 | 100.0% | 55.3% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.74 | 61.0 | 6.19e-01 | 92.6% | 97.0% |
| 3dkqA02 | 4.10.860.20 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain | 0.73 | 48.0 | 5.37e-01 | 70.6% | 97.9% |
| 1rq0A01 | 6.10.140.160 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 60.0 | 5.71e-01 | 95.6% | 79.5% |
| 4u1cA01 | 4.10.860.10 | Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › UVR domain | 0.70 | 47.0 | 5.14e-01 | 75.0% | 92.3% |
| 2ewfA02 | 1.20.1270.310 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.70 | 49.0 | 4.67e-01 | 76.5% | 61.7% |
| 2jdiG01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.70 | 50.0 | 5.22e-01 | 76.5% | 96.7% |
| 2vkzA02 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.70 | 55.0 | 3.67e-01 | 85.3% | 24.0% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.70 | 60.0 | 4.72e-01 | 97.1% | 53.1% |
| 2uv8A07 | 6.10.140.1410 | Special › Helix non-globular › Helix Hairpins › | 0.68 | 56.0 | 5.18e-01 | 91.2% | 70.6% |
| 1zhcA00 | 6.10.280.50 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 45.0 | 4.44e-01 | 76.5% | 73.7% |
| 4h63H01 | 1.20.58.1710 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 55.0 | 5.43e-01 | 100.0% | 100.0% |
| 3tklB01 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 50.0 | 5.21e-01 | 89.7% | 100.0% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4029610 | 3755.4.1.57 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › MSP1_C | 0.96 | 89.0 | 5.37e-01 | 97.1% | 24.0% |
| 5029347 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.94 | 88.0 | 5.11e-01 | 98.5% | 16.0% |
| 3928077 | 3636.1.1.0 ↗ | a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain | 0.94 | 84.0 | 6.28e-01 | 92.6% | 51.0% |
| 4945931 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.94 | 82.0 | 8.14e-01 | 91.2% | 98.6% |
| 4936790 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.93 | 86.0 | 7.20e-01 | 97.1% | 80.0% |
| 3598650 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.93 | 88.0 | 7.63e-01 | 98.5% | 95.8% |
| 3605626 | 192.12.1.0 ↗ | alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM | 0.93 | 81.0 | 6.78e-01 | 91.2% | 70.5% |
| 3520009 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.93 | 86.0 | 8.04e-01 | 97.1% | 93.8% |
| 3631582 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.92 | 73.0 | 6.24e-01 | 82.4% | 70.0% |
| 4646268 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.92 | 76.0 | 7.53e-01 | 86.8% | 97.1% |
| 3462297 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.92 | 85.0 | 8.17e-01 | 97.1% | 93.3% |
| 3693881 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.91 | 79.0 | 7.86e-01 | 91.2% | 98.6% |
| 5026881 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.91 | 80.0 | 7.74e-01 | 92.6% | 96.0% |
| 4934444 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.90 | 79.0 | 7.89e-01 | 92.6% | 98.6% |
| 3235327 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.90 | 83.0 | 5.64e-01 | 98.5% | 32.6% |
| 4543996 | 3600.1.1.1 ↗ | alpha bundles › uncharacterized protein SYNW0670 › uncharacterized protein SYNW0670 › uncharacterized protein SYNW0670 › YlqD | 0.89 | 76.0 | 6.38e-01 | 89.7% | 66.7% |
| 4665988 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.88 | 82.0 | 6.96e-01 | 100.0% | 70.5% |
| 3729994 | 3755.3.1.284 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › Utp11 | 0.88 | 83.0 | 6.46e-01 | 98.5% | 56.2% |
| 4667192 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.88 | 79.0 | 6.91e-01 | 94.1% | 72.6% |
| 4034416 | 2004.1.1.481 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29 | 0.87 | 83.0 | 4.97e-01 | 100.0% | 36.9% |
| 5063166 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.87 | 81.0 | 6.89e-01 | 100.0% | 70.5% |
| 3796505 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.87 | 78.0 | 6.93e-01 | 97.1% | 95.8% |
| 3649223 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.86 | 61.0 | 5.03e-01 | 73.5% | 49.6% |
| 4505128 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.85 | 80.0 | 7.10e-01 | 98.5% | 77.8% |
| 5072279 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.85 | 80.0 | 4.77e-01 | 100.0% | 17.2% |
| 5036054 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.85 | 78.0 | 4.61e-01 | 98.5% | 30.7% |
| 4400912 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.85 | 68.0 | 5.62e-01 | 83.8% | 53.6% |
| 3916884 | 192.29.1.1 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom | 0.84 | 72.0 | 7.44e-01 | 95.6% | 95.4% |
| 3682710 | 2004.1.1.529 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11, DUF6469 | 0.84 | 75.0 | 4.42e-01 | 95.6% | 15.9% |
| 4370630 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.83 | 75.0 | 6.73e-01 | 95.6% | 74.4% |
| 3990125 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.82 | 74.0 | 6.34e-01 | 100.0% | 70.5% |
| 2388286 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.82 | 68.0 | 6.66e-01 | 89.7% | 90.3% |
| 5082509 | 101.1.2.31 ↗ | alpha arrays › HTH › HTH › winged helix domain › TFIIE_alpha | 0.81 | 68.0 | 5.34e-01 | 88.2% | 57.7% |
| 3781132 | 3755.4.1.48 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › V_ATPase_I | 0.81 | 74.0 | 5.64e-01 | 100.0% | 52.7% |
| 3627873 | 605.1.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase | 0.76 | 70.0 | 6.79e-01 | 98.5% | 89.3% |
| 3201381 | 192.8.1.139 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Fung_rhodopsin | 0.75 | 62.0 | 6.05e-01 | 95.6% | 81.3% |
| 2661265 | 192.29.1.1 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom | 0.73 | 61.0 | 5.79e-01 | 94.1% | 84.1% |
| 3461932 | 3922.1.1.189 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › DUF630 | 0.73 | 65.0 | 5.81e-01 | 100.0% | 85.3% |
| 4806319 | 3755.1.1.2 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › YscO-like | 0.71 | 61.0 | 5.76e-01 | 98.5% | 98.8% |
| 3788511 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.71 | 61.0 | 3.73e-01 | 100.0% | 26.2% |
| 3189035 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.68 | 58.0 | 5.65e-01 | 94.1% | 88.0% |
D3
medium
residues 308-368
Domain cluster:
representative
CATH (8)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3u1nB01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.94 | 88.0 | 5.34e-01 | 100.0% | 19.8% |
| 2honB01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.87 | 75.0 | 4.75e-01 | 100.0% | 21.3% |
| 2x4hA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.62 | 43.0 | 3.39e-01 | 73.8% | 62.0% |
| 1i7dA02 | 1.10.460.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 2 › Topoisomerase I, domain 2 | 0.60 | 49.0 | 3.56e-01 | 93.4% | 91.7% |
| 3k4oA00 | 3.40.1160.10 | Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like | 0.56 | 48.0 | 3.25e-01 | 100.0% | 38.8% |
| 2debA03 | 3.30.559.70 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Choline/Carnitine o-acyltransferase, domain 2 | 0.54 | 46.0 | 3.06e-01 | 100.0% | 61.0% |
| 1xdsB01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 37.0 | 3.28e-01 | 75.4% | 63.0% |
| 2ywrA00 | 3.40.50.170 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain | 0.51 | 42.0 | 3.02e-01 | 100.0% | 64.2% |
ECOD (18)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1118688 | 131.1.1.3 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD | 0.97 | 92.0 | 5.23e-01 | 100.0% | 13.4% |
| 3810621 | 131.1.1.3 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD | 0.96 | 90.0 | 5.19e-01 | 100.0% | 13.5% |
| 1108429 | 131.1.1.0 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like | 0.96 | 91.0 | 5.21e-01 | 100.0% | 13.5% |
| 3641475 | 131.1.1.5 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD,HD_assoc_2 | 0.96 | 91.0 | 5.23e-01 | 100.0% | 13.4% |
| 3305107 | 131.1.1.5 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD,HD_assoc_2 | 0.95 | 90.0 | 5.22e-01 | 100.0% | 13.9% |
| 5074639 | 131.1.1.0 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like | 0.91 | 81.0 | 5.02e-01 | 100.0% | 19.8% |
| 4970001 | 131.1.1.0 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like | 0.90 | 75.0 | 4.41e-01 | 95.1% | 13.5% |
| 3596396 | 131.1.1.3 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD | 0.89 | 83.0 | 4.72e-01 | 100.0% | 14.0% |
| 5037358 | 131.1.1.0 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like | 0.86 | 73.0 | 5.07e-01 | 95.1% | 30.3% |
| 4971620 | 131.1.1.3 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD | 0.75 | 63.0 | 3.86e-01 | 100.0% | 15.1% |
| 4378587 | 131.1.1.3 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD | 0.71 | 60.0 | 3.69e-01 | 100.0% | 17.2% |
| 1145730 | 3841.1.1.0 ↗ | 0.65 | 46.0 | 3.25e-01 | 100.0% | 22.9% | |
| 3249793 | 5001.1.1.80 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Dicty_CAR | 0.64 | 53.0 | 3.42e-01 | 93.4% | 83.1% |
| 5004081 | 3239.1.1.1 ↗ | alpha complex topology › Cas1 › Cas1 › Cas1 › Cas_Cas1 | 0.60 | 51.0 | 3.28e-01 | 100.0% | 23.1% |
| 4998551 | 7512.1.1.30 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 | 0.54 | 46.0 | 3.26e-01 | 100.0% | 42.4% |
| 4997796 | 2006.1.6.45 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like › PF30231 | 0.52 | 45.0 | 2.94e-01 | 100.0% | 49.1% |
| 4941343 | 247.1.1.11 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 | 0.52 | 39.0 | 2.65e-01 | 88.5% | 45.7% |
| 3248047 | 3016.1.1.13 ↗ | a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › SepSecS | 0.50 | 37.0 | 2.91e-01 | 82.0% | 84.9% |
D4
medium
residues 389-460
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 41.0 | 3.70e-01 | 100.0% | 46.4% |
| 2mpkA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.64 | 32.0 | 3.24e-01 | 97.2% | 43.2% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.61 | 39.0 | 3.94e-01 | 100.0% | 63.5% |
| 4an8A02 | 1.10.132.100 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.60 | 52.0 | 4.43e-01 | 100.0% | 88.5% |
| 3c1yA02 | 1.20.1260.110 | Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region | 0.59 | 37.0 | 2.95e-01 | 98.6% | 30.4% |
| 4g6dB02 | 6.10.140.1800 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 44.0 | 4.36e-01 | 100.0% | 75.3% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 33.0 | 2.73e-01 | 100.0% | 27.2% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 44.0 | 4.36e-01 | 100.0% | 77.9% |
| 4nooB00 | 1.10.8.1160 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.56 | 41.0 | 3.76e-01 | 77.8% | 86.3% |
| 4k7bA00 | 1.20.120.1740 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sodium ion translocating NADH-quinone reductase subunit C-like | 0.56 | 37.0 | 3.20e-01 | 97.2% | 44.1% |
| 4ioeA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.55 | 41.0 | 3.84e-01 | 100.0% | 65.5% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.54 | 42.0 | 3.68e-01 | 100.0% | 56.1% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.54 | 40.0 | 3.81e-01 | 100.0% | 67.1% |
| 3rq9A00 | 1.10.287.2500 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.52 | 36.0 | 3.51e-01 | 98.6% | 66.7% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.51 | 35.0 | 2.72e-01 | 72.2% | 47.3% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.50 | 44.0 | 3.45e-01 | 100.0% | 72.0% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.50 | 38.0 | 3.72e-01 | 100.0% | 73.2% |
| 2qq8A02 | 1.10.8.270 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › putative rabgap domain of human tbc1 domain family member 14 like domains | 0.50 | 34.0 | 3.15e-01 | 70.8% | 65.6% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5062158 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.75 | 41.0 | 4.09e-01 | 100.0% | 52.0% |
| 3969942 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.71 | 45.0 | 3.78e-01 | 100.0% | 40.0% |
| 2674763 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.62 | 39.0 | 3.93e-01 | 100.0% | 62.7% |
| 3783776 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.58 | 43.0 | 3.89e-01 | 77.8% | 83.2% |
| 3200160 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.57 | 37.0 | 3.27e-01 | 98.6% | 43.6% |
| 3441901 | 632.1.1.13 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Rx_N | 0.57 | 37.0 | 3.64e-01 | 98.6% | 60.0% |
| 4402843 | 604.1.1.20 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › AKNA | 0.56 | 41.0 | 3.53e-01 | 100.0% | 48.7% |
| 3448091 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.55 | 43.0 | 3.67e-01 | 100.0% | 52.6% |
| 4365052 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.54 | 43.0 | 3.89e-01 | 100.0% | 64.2% |
| 5058630 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.54 | 39.0 | 4.12e-01 | 76.4% | 100.0% |
| 3498899 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.53 | 45.0 | 3.77e-01 | 100.0% | 97.0% |
| 4180835 | 5041.1.1.1 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C | 0.53 | 47.0 | 4.82e-01 | 100.0% | 98.6% |
| 3876590 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.52 | 36.0 | 3.43e-01 | 98.6% | 62.4% |
| 4934327 | 604.5.1.1 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU_div | 0.51 | 45.0 | 3.24e-01 | 100.0% | 99.1% |
| 3548194 | 192.2.1.18 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING | 0.50 | 37.0 | 3.30e-01 | 100.0% | 52.7% |
D5
medium
residues 461-506_546-598
Domain cluster:
rep: Phosphohydrolase__YP_009481642__Pandoravirus_neocaledonia__2107708__D414-457_497-544