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Phosphotransferase

Euk-Vir

Human_betaherpesvirus_6B

Phosphotransferase__NP_050248__Human_betaherpesvirus_6B__32604

Identity

Accession:
NP_050248 ↗
Protein ID:
Phosphotransferase
Kingdom:
euk

Quality

74.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 157-277_344-373
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06734.19 best UL97 44.6 2.00e-11 38.4% 17.6%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5cqgA02 3.10.10.20 Alpha Beta › Roll › HIV Type 1 Reverse Transcriptase; Chain A, domain 1 › 0.65 20.0 2.97e-01 82.1% 58.3%
4f0fA01 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.64 39.0 4.94e-01 73.5% 100.0%
ECOD (17)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3177424 206.1.1.72 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Pkinase_fungal 0.65 49.0 3.62e-01 78.1% 55.6%
3724695 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.62 48.0 3.98e-01 80.1% 86.3%
3180087 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.61 47.0 3.60e-01 79.5% 52.0%
3287245 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.60 46.0 3.70e-01 80.8% 86.7%
3728072 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 46.0 3.72e-01 81.5% 73.8%
4521206 331.1.1.6 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › DUF3378 0.58 23.0 3.36e-01 72.2% 78.6%
3731058 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.58 44.0 3.56e-01 77.5% 83.8%
4049898 206.1.1.11 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH 0.57 45.0 3.53e-01 81.5% 84.3%
3734065 206.1.1.74 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr 0.57 42.0 3.47e-01 76.2% 81.1%
4958423 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.57 42.0 3.75e-01 77.5% 67.0%
4937854 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.56 44.0 3.53e-01 81.5% 72.9%
3270541 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.56 53.0 3.93e-01 100.0% 52.2%
4073873 206.1.1.15 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Fructosamin_kin 0.55 43.0 3.64e-01 82.1% 91.8%
4284025 206.1.2.4 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › SAICAR synthase › Ins_P5_2-kin 0.55 39.0 3.29e-01 73.5% 97.3%
5027718 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.54 38.0 3.63e-01 72.2% 74.4%
5054665 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.54 38.0 3.45e-01 71.5% 73.8%
5042309 4312.1.1.0 a+b two layers › RelE-like › RelE-like › RelE-like 0.50 29.0 3.57e-01 82.8% 93.3%
D2 medium residues 278-343
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06734.19 best UL97 32.0 1.50e-07 37.9% 15.0%
D3 medium residues 374-563
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF06734.19 best UL97 224.6 1.30e-66 65.8% 69.0%
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ztaA00 1.10.490.130 Mainly Alpha › Orthogonal Bundle › Globin-like › 0.60 33.0 3.88e-01 75.3% 74.8%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 34.0 4.14e-01 84.2% 91.7%
2e8gA01 1.20.1440.150 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.56 34.0 4.11e-01 92.6% 90.3%
6kobA01 1.20.210.10 Mainly Alpha › Up-down Bundle › Cytochrome C Oxidase; Chain A › Cytochrome c oxidase-like, subunit I domain 0.55 46.0 3.25e-01 87.9% 69.4%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 38.0 4.08e-01 94.2% 81.6%
3r2cA00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.55 38.0 4.32e-01 73.7% 95.7%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.55 32.0 3.56e-01 84.7% 72.1%
1d2tA00 1.20.144.10 Mainly Alpha › Up-down Bundle › Vanadium-containing Chloroperoxidase; domain 1 › Phosphatidic acid phosphatase type 2/haloperoxidase 0.54 41.0 3.93e-01 79.5% 82.9%
1tjoB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.54 36.0 3.79e-01 93.7% 73.7%
1sqgA01 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.53 36.0 4.10e-01 75.3% 92.9%
2qqyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 34.0 3.83e-01 93.7% 86.2%
2incB00 1.10.620.20 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A 0.52 43.0 3.65e-01 87.4% 60.2%
1eq1A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.52 37.0 3.98e-01 91.1% 83.1%
1vcsA00 1.20.58.400 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins 0.51 25.0 3.32e-01 70.5% 86.3%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.50 34.0 3.71e-01 94.2% 85.2%
1qoyA00 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.50 41.0 3.46e-01 85.3% 82.2%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3467149 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.64 31.0 3.78e-01 82.1% 68.8%
3581716 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.63 38.0 4.54e-01 92.6% 86.9%
3404805 603.2.1.9 alpha bundles › STAT-like › STAT › STAT › 7tm_6 0.57 43.0 3.78e-01 76.8% 77.5%
3217424 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.51 43.0 3.35e-01 90.5% 92.3%
4029831 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 39.0 3.24e-01 78.4% 74.7%
3573786 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.50 33.0 3.27e-01 77.4% 61.5%