Back to structures

RNA-dependent_RNA_polymerase,_partial

Euk-Vir

Asikkala_orthohantavirus

RNA-dependent_RNA_polymerase,_partial__YP_009664720__Asikkala_orthohantavirus__1980458

Identity

Accession:
YP_009664720 ↗
Protein ID:
RNA-dependent_RNA_polymerase,_partial
Kingdom:
euk

Quality

90.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 180-225_314-431
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF04196.18 best Bunya_RdRp 108.5 4.90e-31 72.6% 14.0%
PF04196.18 Bunya_RdRp 34.2 1.50e-08 29.9% 6.8%
CATH (72)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2mq8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.74 44.0 5.25e-01 72.0% 86.6%
1yz7A02 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.72 41.0 5.32e-01 78.0% 100.0%
3pm9A04 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.71 39.0 5.19e-01 78.7% 100.0%
7qh2C03 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 35.0 4.87e-01 73.8% 100.0%
2a6mA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.70 48.0 5.33e-01 82.3% 86.9%
2c2nA02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.69 35.0 4.81e-01 70.1% 100.0%
2kl8A00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.69 35.0 4.63e-01 70.1% 91.8%
3tqeA02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.69 33.0 4.71e-01 81.7% 100.0%
2f5gA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.69 45.0 5.04e-01 80.5% 83.8%
2pd1A01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 40.0 5.10e-01 87.8% 100.0%
2r7rA04 3.30.70.2480 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 48.0 4.89e-01 100.0% 74.5%
1q8bA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 38.0 4.89e-01 72.0% 95.7%
2x3gA00 3.30.70.1910 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.68 45.0 5.22e-01 92.1% 94.0%
3gz7B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 40.0 5.01e-01 78.7% 98.0%
2lqjA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.66 38.0 4.85e-01 89.0% 97.9%
2rrnA01 3.30.70.2040 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 34.0 4.78e-01 82.9% 100.0%
4bbyA05 3.30.300.330 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › 0.66 43.0 5.18e-01 85.4% 100.0%
2gffA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 37.0 4.72e-01 70.1% 93.8%
2pgcC01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 39.0 4.91e-01 71.3% 97.9%
5ajiB03 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 37.0 4.75e-01 76.2% 95.8%
2khdA00 3.30.70.860 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 35.0 4.19e-01 80.5% 76.9%
2anrA02 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.65 32.0 4.50e-01 76.2% 100.0%
3kkfA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 40.0 4.80e-01 86.6% 93.3%
1zpvA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.64 35.0 4.62e-01 87.8% 100.0%
4dpoB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 39.0 4.80e-01 82.3% 97.0%
2yweA03 3.30.70.870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Elongation Factor G (Translational Gtpase), domain 3 0.64 34.0 4.55e-01 73.8% 100.0%
3e8oB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 36.0 4.52e-01 70.1% 91.0%
1lq9A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 42.0 4.96e-01 93.3% 97.3%
4hl9A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 37.0 4.71e-01 76.8% 98.9%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.63 33.0 3.35e-01 71.3% 47.9%
3fgvA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 36.0 4.53e-01 71.3% 96.8%
2f1fA01 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.63 33.0 4.34e-01 72.0% 100.0%
3hx9B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 36.0 4.48e-01 70.7% 92.9%
4zosB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 38.0 4.69e-01 88.4% 100.0%
1iujA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 38.0 4.66e-01 77.4% 97.1%
2pgcA02 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 39.0 4.72e-01 89.0% 98.1%
5t0oA02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.61 36.0 4.41e-01 83.5% 92.2%
1x7vA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 36.0 4.38e-01 72.0% 93.9%
2fyxA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.61 45.0 5.01e-01 84.8% 96.9%
1tuwA00 3.30.70.1090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel. 0.61 38.0 4.61e-01 89.0% 97.2%
1vdhA01 3.30.70.1030 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Apc35880; domain 1 0.60 37.0 4.21e-01 79.9% 81.0%
1y0hB00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 36.0 4.44e-01 78.0% 98.0%
6hhnA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 35.0 4.37e-01 70.7% 100.0%
2nyiA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.59 33.0 4.20e-01 78.0% 96.7%
1x8dA01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 36.0 4.44e-01 70.7% 100.0%
4c8yA01 3.30.70.1890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 37.0 4.48e-01 79.3% 97.1%
4mt1A02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.59 36.0 4.25e-01 81.1% 92.2%
1r89A03 3.30.70.590 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Poly(A) polymerase predicted RNA binding domain 0.59 44.0 4.79e-01 97.0% 94.8%
4za1C00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 33.0 4.11e-01 73.2% 93.5%
5k9fA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 37.0 4.46e-01 77.4% 98.1%
1q2lA01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.59 41.0 3.58e-01 72.0% 70.2%
4er8A00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.59 44.0 4.49e-01 78.7% 91.5%
2g47A03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.58 44.0 3.94e-01 78.0% 87.2%
1vqyB01 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.58 34.0 4.27e-01 70.7% 97.9%
6ofsA03 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.58 46.0 4.12e-01 81.1% 79.1%
5ixuA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 35.0 4.33e-01 77.4% 98.0%
6ofsA04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.57 45.0 4.32e-01 81.1% 94.0%
3eoqA01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.55 43.0 3.91e-01 80.5% 79.6%
8b6jb01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.55 42.0 3.90e-01 79.9% 82.0%
1bccB01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.54 43.0 3.92e-01 81.7% 80.5%
3ig5A02 3.30.590.50 Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › 0.54 42.0 3.29e-01 81.7% 77.4%
3m05B01 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 31.0 3.90e-01 72.0% 97.8%
1qltA03 3.40.462.10 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › FAD-linked oxidases, C-terminal domain 0.53 44.0 3.98e-01 90.2% 99.1%
4gs5A02 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.53 32.0 3.93e-01 71.3% 94.3%
5abxA00 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.53 46.0 4.54e-01 99.4% 88.4%
5fxdA03 3.40.462.10 Alpha Beta › 3-Layer(aba) Sandwich › Vanillyl-alcohol Oxidase; Chain A, domain 3 › FAD-linked oxidases, C-terminal domain 0.52 43.0 3.83e-01 89.0% 86.7%
3go9A02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 41.0 3.70e-01 82.9% 84.3%
2g47A04 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 42.0 3.71e-01 86.6% 90.4%
4xeaA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 40.0 3.80e-01 81.1% 89.6%
3cx5B02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 37.0 4.03e-01 81.7% 91.1%
2jgbA01 3.30.760.10 Alpha Beta › 2-Layer Sandwich › RNA Cap, Translation Initiation Factor Eif4e › RNA Cap, Translation Initiation Factor Eif4e 0.51 46.0 4.52e-01 100.0% 92.5%
4fpwB00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.50 40.0 4.06e-01 82.9% 91.9%
ECOD (82)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5000281 304.55.2.0 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.80 42.0 5.85e-01 70.1% 100.0%
4944179 304.43.1.0 a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 0.75 45.0 5.64e-01 79.3% 98.0%
3986660 304.55.2.0 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.72 42.0 5.33e-01 78.0% 96.0%
5053356 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.72 42.0 5.34e-01 78.7% 98.9%
4994641 304.19.1.1 a+b two layers › Alpha-beta plaits › eIF-2-alpha, C-terminal domain › eIF-2-alpha, C-terminal domain › EIF_2_alpha 0.71 42.0 5.36e-01 79.9% 100.0%
2455618 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.70 39.0 4.38e-01 81.1% 68.8%
2777205 304.159.1.1 a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB › Lant_dehydr_C 0.69 40.0 5.13e-01 78.0% 100.0%
4928084 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.69 39.0 5.03e-01 80.5% 96.8%
5116 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.69 45.0 5.04e-01 80.5% 83.8%
3340180 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.68 42.0 5.20e-01 76.8% 99.0%
4098707 304.159.1.1 a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB › Lant_dehydr_C 0.68 42.0 5.22e-01 90.9% 99.0%
3613200 304.134.1.0 a+b two layers › Alpha-beta plaits › MJ1480-like › MJ1480-like 0.68 38.0 4.91e-01 70.1% 97.8%
139956 304.8.1.16 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › 117-like_vir 0.68 45.0 5.22e-01 92.1% 94.0%
3985106 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.67 46.0 5.48e-01 87.2% 100.0%
4976493 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.67 48.0 5.54e-01 95.1% 100.0%
5021604 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.67 46.0 5.44e-01 82.3% 100.0%
2533026 304.159.1.1 a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB › Lant_dehydr_C 0.67 40.0 4.78e-01 91.5% 88.1%
3729382 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.67 40.0 4.81e-01 81.1% 88.2%
3732824 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.67 38.0 4.78e-01 71.3% 94.7%
4943463 304.43.1.0 a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 0.67 38.0 4.70e-01 79.9% 91.0%
4370515 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.66 38.0 4.79e-01 71.3% 93.0%
4959193 304.39.1.0 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain 0.66 36.0 4.71e-01 73.2% 98.8%
4396408 304.20.1.5 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › tRNA_synt_2f 0.66 50.0 4.54e-01 79.3% 94.1%
3709394 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.66 39.0 4.34e-01 72.0% 73.8%
4932448 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.65 37.0 4.69e-01 71.3% 97.8%
5002487 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.65 47.0 5.13e-01 89.0% 88.9%
4053917 304.20.1.5 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › tRNA_synt_2f 0.65 50.0 4.47e-01 79.9% 90.0%
3961062 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.65 37.0 4.78e-01 70.1% 100.0%
4126752 304.20.1.5 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › tRNA_synt_2f 0.65 50.0 4.48e-01 78.7% 90.9%
137323 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.65 40.0 4.80e-01 86.6% 93.3%
3286580 304.159.1.1 a+b two layers › Alpha-beta plaits › Alpha-beta plait domain in NisB › Alpha-beta plait domain in NisB › Lant_dehydr_C 0.65 40.0 4.90e-01 90.2% 99.0%
402953 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.65 46.0 4.95e-01 87.8% 84.4%
4032118 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.64 47.0 5.11e-01 87.2% 89.3%
3948173 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.64 37.0 4.58e-01 70.7% 93.0%
4484241 304.55.2.7 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › tRNA_synt_2f 0.64 49.0 4.41e-01 79.9% 94.1%
5039525 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.63 36.0 4.59e-01 70.7% 100.0%
3955607 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.63 39.0 4.79e-01 79.3% 100.0%
4980887 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.63 39.0 4.78e-01 79.3% 100.0%
3838293 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.63 47.0 5.25e-01 89.0% 100.0%
3037399 304.51.1.5 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas_Csy4 0.63 34.0 4.57e-01 90.9% 100.0%
3972158 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.63 37.0 4.67e-01 78.7% 100.0%
3972989 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.63 39.0 4.71e-01 87.2% 99.0%
3992335 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.63 38.0 4.74e-01 77.4% 99.0%
3728165 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.63 39.0 4.75e-01 91.5% 100.0%
5029644 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.62 37.0 4.43e-01 75.0% 89.5%
5053097 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.62 35.0 4.36e-01 70.1% 92.6%
4055479 304.20.1.5 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › tRNA_synt_2f 0.62 48.0 4.30e-01 79.9% 96.0%
3965732 304.13.1.1 a+b two layers › Alpha-beta plaits › Hypothetical protein VC0424 › Hypothetical protein VC0424 › RraB 0.62 33.0 4.07e-01 72.0% 82.0%
4022825 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.62 38.0 4.57e-01 82.3% 93.3%
4994778 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.62 46.0 5.09e-01 87.8% 95.4%
3511024 304.28.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › ACR_tran 0.62 38.0 4.61e-01 88.4% 98.0%
5160 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.62 38.0 4.66e-01 77.4% 97.1%
3973625 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.62 37.0 4.58e-01 81.1% 100.0%
3732290 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.62 36.0 4.54e-01 72.0% 97.9%
3574195 317.1.1.1 a+b two layers › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › Translation initiation factor eIF4e and phosphothreonine lyase › IF4E 0.62 44.0 4.93e-01 100.0% 93.1%
3973601 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.61 36.0 4.45e-01 77.4% 95.0%
4025874 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.61 37.0 4.42e-01 81.1% 91.4%
4438667 304.42.1.0 a+b two layers › Alpha-beta plaits › Molybdenum cofactor biosynthesis protein C, MoaC › Molybdenum cofactor biosynthesis protein C, MoaC 0.61 37.0 4.44e-01 74.4% 92.4%
4098715 304.4.1.7 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › Cyclase_polyket 0.61 39.0 4.61e-01 88.4% 95.4%
5059197 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.61 46.0 4.94e-01 82.3% 91.4%
4026407 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.61 41.0 4.54e-01 79.9% 86.2%
4066041 304.55.2.7 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › tRNA_synt_2f 0.61 46.0 4.18e-01 79.3% 92.7%
4659364 304.55.2.7 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › tRNA_synt_2f 0.60 46.0 4.17e-01 79.3% 91.6%
3322835 304.20.1.5 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › tRNA_synt_2f 0.60 46.0 4.10e-01 79.9% 90.0%
4576325 304.55.2.7 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › tRNA_synt_2f 0.60 46.0 4.04e-01 79.9% 90.4%
4147456 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.60 43.0 4.91e-01 93.3% 98.4%
3973540 304.55.2.0 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.59 44.0 4.47e-01 77.4% 97.6%
151843 304.55.2.0 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like 0.59 44.0 4.49e-01 78.7% 91.5%
3164568 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.58 43.0 4.33e-01 77.4% 97.6%
3493779 309.1.1.8 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16_M 0.57 45.0 3.97e-01 82.9% 99.2%
4928824 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.57 31.0 3.94e-01 76.2% 90.5%
4993060 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.57 45.0 4.66e-01 88.4% 90.0%
3281659 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.56 31.0 3.85e-01 73.2% 86.0%
3934872 3122.1.1.2 a+b complex topology › MESD › MESD › MESD › SCVP 0.56 34.0 4.05e-01 70.7% 91.4%
4566039 304.4.1.4 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel › ABM 0.56 35.0 4.26e-01 89.0% 100.0%
3838738 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.55 38.0 4.30e-01 76.8% 92.8%
4956868 304.102.1.0 a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase 0.55 38.0 3.40e-01 75.6% 50.7%
3713000 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.54 36.0 4.23e-01 83.5% 100.0%
3902600 304.133.1.1 a+b two layers › Alpha-beta plaits › 26 kDa periplasmic immunogenic protein › 26 kDa periplasmic immunogenic protein › SIMPL 0.53 32.0 3.90e-01 70.1% 97.0%
5078562 304.55.2.1 a+b two layers › Alpha-beta plaits › Origin of replication-binding domains › Transposase IS200-like › Y1_Tnp 0.52 40.0 3.87e-01 79.9% 91.9%
5046168 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.52 43.0 3.80e-01 87.2% 83.7%
3411428 304.47.1.1 a+b two layers › Alpha-beta plaits › SEA domain › SEA domain › SEA 0.52 40.0 4.31e-01 80.5% 99.3%
D2 high residues 432-484
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04196.18 best Bunya_RdRp 45.0 8.20e-12 100.0% 6.9%
CATH (49)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6xpdA01 1.20.1510.10 Mainly Alpha › Up-down Bundle › Alpha-lytic protease prodomain-like › Cation efflux protein transmembrane domain 0.77 54.0 3.56e-01 73.6% 30.2%
2yvkA01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.75 65.0 4.77e-01 100.0% 44.6%
2a0uB01 1.20.120.420 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › translation initiation factor eif-2b, domain 1 0.74 59.0 4.20e-01 88.7% 43.1%
5nohA00 1.20.120.1350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain 0.73 46.0 3.66e-01 75.5% 33.0%
6dv2G02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.71 54.0 3.71e-01 83.0% 28.8%
1sxjE03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.70 58.0 4.80e-01 94.3% 94.8%
3ecsC01 1.20.120.1070 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Translation initiation factor eIF-2B, N-terminal domain 0.70 59.0 4.95e-01 100.0% 68.0%
4v3iA00 1.25.40.590 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Type IV / VI secretion system, DotU 0.70 60.0 4.34e-01 98.1% 37.9%
1w3bB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 58.0 3.46e-01 96.2% 13.3%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.68 56.0 4.74e-01 98.1% 69.1%
4r42A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 58.0 4.07e-01 100.0% 80.2%
6hftA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 56.0 4.28e-01 96.2% 39.4%
3q9dB01 1.20.58.1050 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 57.0 4.89e-01 98.1% 88.8%
1iq0A03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.66 55.0 4.42e-01 100.0% 74.1%
2yogA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.66 54.0 3.74e-01 96.2% 68.0%
5djsA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.65 57.0 4.16e-01 98.1% 36.4%
1vkeB00 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.65 55.0 4.49e-01 98.1% 50.5%
3ihvA03 1.25.40.900 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.64 56.0 4.17e-01 100.0% 97.1%
7qihA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 53.0 4.36e-01 98.1% 49.5%
1wfdA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.64 51.0 4.31e-01 88.7% 66.7%
3e3vA03 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.64 51.0 5.04e-01 92.5% 85.7%
3b9qA01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.63 57.0 4.77e-01 100.0% 60.7%
1cg5B00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.63 52.0 3.84e-01 92.5% 83.7%
4z7fB00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.63 51.0 3.67e-01 94.3% 38.7%
4htpB00 1.10.3260.10 Mainly Alpha › Orthogonal Bundle › DNA ligase i, domain 1 › DNA ligase, ATP-dependent, N-terminal domain 0.63 50.0 3.48e-01 98.1% 80.6%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.63 50.0 4.59e-01 96.2% 84.4%
2c0kB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.63 53.0 3.93e-01 98.1% 84.6%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 52.0 4.73e-01 96.2% 89.2%
1vw4L02 1.10.246.170 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.62 48.0 4.24e-01 88.7% 74.1%
1x9bA00 1.20.58.290 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hypothetical membrane protein ta0354_69_121. 0.62 48.0 4.80e-01 98.1% 90.6%
2isnB00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.62 53.0 3.27e-01 96.2% 59.0%
1kpsB00 1.25.40.200 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Ran-GTPase activating protein 1, C-terminal domain 0.62 51.0 3.75e-01 96.2% 49.4%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.62 51.0 4.37e-01 100.0% 86.0%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 51.0 3.93e-01 92.5% 91.1%
2fzfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 51.0 3.78e-01 96.2% 87.3%
2oifB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.61 52.0 3.81e-01 98.1% 84.1%
1zk8B02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.60 52.0 3.91e-01 98.1% 50.0%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 49.0 3.51e-01 100.0% 40.9%
2vlaA01 1.10.10.2080 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.60 49.0 4.41e-01 96.2% 70.5%
1k77A00 3.20.20.150 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes 0.60 51.0 3.27e-01 96.2% 26.3%
1cqxA01 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 48.0 3.58e-01 94.3% 75.3%
3ddhA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.59 47.0 4.25e-01 94.3% 72.8%
1a59A02 1.10.230.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450-Terp; domain 2 › Cytochrome P450-Terp, domain 2 0.59 48.0 3.83e-01 90.6% 71.3%
2ii2A04 1.10.220.10 Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin 0.58 47.0 4.26e-01 96.2% 72.2%
3kfwX03 1.20.58.1460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 46.0 4.27e-01 98.1% 82.9%
1wtyA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.57 48.0 3.79e-01 94.3% 89.7%
6a2aA01 1.50.10.130 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › Terpene synthase, N-terminal domain 0.56 46.0 3.24e-01 100.0% 86.9%
1g41A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 43.0 3.09e-01 96.2% 40.9%
2pkeA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.55 43.0 3.91e-01 92.5% 75.6%
ECOD (44)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1560743 4967.1.1.8 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.89 81.0 5.43e-01 100.0% 32.4%
4858176 304.48.1.19 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Bunya_RdRp 0.84 74.0 6.25e-01 100.0% 59.6%
4858192 4967.1.1.32 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Bunya_RdRp 0.83 74.0 5.50e-01 100.0% 40.5%
4883892 4967.1.1.32 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Bunya_RdRp 0.83 73.0 6.17e-01 100.0% 59.6%
4599106 604.9.1.1 alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p 0.77 66.0 5.59e-01 100.0% 72.2%
4320970 109.4.1.1453 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_17 0.75 64.0 4.11e-01 98.1% 22.7%
4025804 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.74 64.0 4.59e-01 100.0% 63.1%
3530124 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.74 62.0 5.55e-01 100.0% 68.8%
3513714 109.4.1.195 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_11 0.73 61.0 4.36e-01 96.2% 40.6%
3941077 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.72 51.0 3.77e-01 75.5% 37.9%
3249842 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 61.0 3.91e-01 96.2% 22.3%
4997718 4969.1.1.0 alpha bundles › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I › thumb domain in bacteriophage RB69-like DNA polymerase I 0.71 58.0 4.34e-01 94.3% 93.8%
3391 138.1.1.11 alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › RFC_C 0.70 58.0 4.80e-01 96.2% 93.9%
3685298 109.4.1.1288 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_11 0.69 58.0 3.43e-01 96.2% 12.1%
3952621 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.69 58.0 5.35e-01 96.2% 79.7%
4145773 101.35.1.4 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › RecX_HTH3 0.68 54.0 5.35e-01 94.3% 85.5%
5001408 4995.1.1.0 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like 0.68 58.0 4.78e-01 98.1% 80.0%
3714093 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 55.0 4.62e-01 96.2% 63.0%
3452645 101.35.1.31 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › Gliadin 0.68 54.0 4.63e-01 94.3% 60.0%
4984499 1030.1.1.0 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 0.68 54.0 4.25e-01 92.5% 57.6%
2875228 138.1.1.0 alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain 0.68 55.0 4.60e-01 96.2% 89.2%
4444405 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 59.0 4.58e-01 100.0% 47.0%
5076898 109.4.1.195 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_11 0.66 58.0 3.87e-01 100.0% 25.7%
1698351 109.4.1.1353 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8, TPR_11, TPR_16 0.66 58.0 4.44e-01 100.0% 42.7%
3701680 4953.1.1.0 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.66 55.0 4.60e-01 98.1% 65.7%
3389963 1134.1.1.0 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.65 53.0 4.91e-01 94.3% 85.7%
3236916 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.65 52.0 4.24e-01 90.6% 46.7%
3648998 604.3.1.1 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG 0.65 53.0 4.58e-01 98.1% 75.6%
3091020 109.4.1.17 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cullin 0.64 51.0 3.51e-01 100.0% 48.3%
3721044 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.64 53.0 3.19e-01 100.0% 17.2%
3625495 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.64 54.0 3.92e-01 98.1% 76.2%
3968904 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 56.0 4.65e-01 100.0% 56.8%
3936005 604.12.1.2 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.64 55.0 4.50e-01 100.0% 63.8%
3938517 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.62 51.0 3.66e-01 100.0% 48.1%
3680364 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.62 51.0 3.65e-01 98.1% 72.0%
3298 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.61 52.0 3.79e-01 96.2% 82.8%
3421325 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.61 49.0 4.40e-01 96.2% 77.5%
3244338 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.60 51.0 3.65e-01 100.0% 78.7%
4380725 101.1.1.0 alpha arrays › HTH › HTH › Three-helical HTH 0.60 44.0 4.09e-01 92.5% 60.0%
3601936 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.60 51.0 3.81e-01 98.1% 63.6%
3188279 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 47.0 3.20e-01 100.0% 21.7%
3235045 106.1.1.1 alpha arrays › Globin-like › Globin-like › Globin-like › Globin 0.56 46.0 3.42e-01 100.0% 64.4%
4964419 131.1.1.3 alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD 0.56 44.0 2.96e-01 96.2% 34.1%
3276944 604.12.1.2 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.54 45.0 4.12e-01 100.0% 90.7%
D3 medium residues 1-55_228-259
PDB
Domain cluster: representative
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5w0kA01 3.90.380.20 Alpha Beta › Alpha-Beta Complex › Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 › Herpesvirus glycoprotein H, domain D-II 0.54 46.0 3.18e-01 97.7% 53.2%
2xbkA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.53 43.0 2.83e-01 88.5% 67.5%
4e3wA00 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.51 38.0 2.63e-01 80.5% 31.0%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4679004 192.7.1.3 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Phe_tRNA-synt_N 0.53 32.0 3.10e-01 100.0% 51.0%
3375038 170.2.1.25 alpha bundles › Retrovirus capsid protein › Retrovirus capsid protein N-terminal domain › Retrovirus capsid protein N-terminal domain › DUF7746 0.53 29.0 3.16e-01 82.8% 62.7%
D4 medium residues 56-172_260-313
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF04196.18 best Bunya_RdRp 87.7 9.70e-25 70.2% 17.4%
PF04196.18 Bunya_RdRp 36.3 3.40e-09 32.2% 7.3%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1mukA02 3.90.1850.10 Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 0.62 58.0 4.09e-01 100.0% 51.2%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1695458 304.48.1.7 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flu_PB1 0.79 75.0 5.31e-01 100.0% 62.8%
1411401 304.48.1.7 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flu_PB1 0.79 74.0 5.23e-01 100.0% 64.2%
4859811 304.48.1.7 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flu_PB1 0.76 72.0 5.18e-01 100.0% 61.2%
3097450 304.48.1.12 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Mononeg_RNA_pol 0.67 63.0 4.71e-01 100.0% 72.4%
5368 304.48.1.23 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_5 0.62 58.0 4.39e-01 100.0% 65.9%
4152428 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.62 54.0 4.20e-01 93.0% 57.7%
2850105 304.48.1.19 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Bunya_RdRp 0.61 57.0 4.87e-01 98.2% 64.5%
3589612 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.60 56.0 4.43e-01 99.4% 67.3%
4497954 304.48.1.73 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1, RVT_N 0.60 55.0 4.51e-01 100.0% 69.7%
3923013 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.60 54.0 4.28e-01 98.2% 62.6%
3983816 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.59 43.0 3.73e-01 73.7% 66.4%
3945039 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.59 54.0 4.34e-01 100.0% 64.8%
4004424 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.58 54.0 4.15e-01 100.0% 58.9%
5018583 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.58 54.0 4.38e-01 100.0% 66.3%
3173834 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.58 54.0 4.03e-01 100.0% 51.5%
4461237 4967.1.1.0 alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.58 53.0 3.75e-01 100.0% 41.2%
4071235 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.57 53.0 3.74e-01 100.0% 42.4%
4516798 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.57 53.0 3.85e-01 100.0% 47.0%
223786 304.48.1.16 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RdRP_4 0.57 52.0 4.23e-01 100.0% 70.6%
5002351 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.56 51.0 3.99e-01 99.4% 58.7%
1697857 304.48.1.30 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › CPV_RdRP_pol_dom 0.54 50.0 3.95e-01 100.0% 64.9%
5078830 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.54 46.0 3.95e-01 91.2% 77.7%
4138932 304.48.1.72 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_N 0.52 48.0 3.95e-01 100.0% 70.0%
5029718 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.52 46.0 3.67e-01 95.9% 58.8%
1827765 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.52 47.0 3.92e-01 98.8% 68.4%