←Back to structures
RNA-dependent_RNA_polymerase-like_protein
Euk-VirAnopheline-associated_C_virus_Viruses.
RNA-dependent_RNA_polymerase-like_protein__YP_009011225__Anopheline-associated_C_virus_Viruses.__X
Identity
- Accession:
- YP_009011225 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase-like_protein
- Kingdom:
- euk
Quality
70.2
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 120-355
Domain cluster:
rep: RNA-dependent_RNA_polymerase__YP_009337879__Hubei_noda-like_virus_9__1922989__D136-259_287-345
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19223.6 best | Chropara_Vmeth | 224.3 | 2.90e-66 | 86.0% | 63.8% |
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8k5lA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.73 | 55.0 | 5.99e-01 | 78.0% | 99.5% |
| 2p7iA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.72 | 54.0 | 5.60e-01 | 77.5% | 100.0% |
| 3hnrA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.71 | 56.0 | 6.16e-01 | 80.5% | 99.0% |
| 2p8jA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.70 | 53.0 | 5.68e-01 | 77.1% | 97.6% |
| 5cm2Z00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.70 | 52.0 | 5.88e-01 | 86.4% | 98.4% |
| 3ofkA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.69 | 51.0 | 5.46e-01 | 78.8% | 86.8% |
| 2r3sA03 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.69 | 52.0 | 5.52e-01 | 78.0% | 90.1% |
| 4a6dA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.68 | 54.0 | 5.34e-01 | 81.8% | 98.4% |
| 3dtnA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.68 | 48.0 | 5.33e-01 | 78.8% | 89.8% |
| 3lstA02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.66 | 52.0 | 5.19e-01 | 80.9% | 98.0% |
| 3ftdA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.64 | 47.0 | 5.33e-01 | 78.4% | 98.9% |
| 1o54A02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.62 | 47.0 | 5.12e-01 | 79.7% | 94.8% |
| 1qyrA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.60 | 46.0 | 5.14e-01 | 78.8% | 99.5% |
| 5yrzB00 | 3.30.920.30 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Hypothetical protein. | 0.59 | 12.0 | 2.61e-01 | 89.0% | 69.0% |
| 1yb2A00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.57 | 46.0 | 4.67e-01 | 93.2% | 85.2% |
| 2va0A00 | 3.30.450.160 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › | 0.54 | 25.0 | 3.70e-01 | 89.8% | 100.0% |
| 3c8cB01 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.54 | 29.0 | 3.74e-01 | 91.9% | 92.1% |
| 1iwmA00 | 2.50.20.10 | Mainly Beta › Clam › outer membrane lipoprotein receptor (LolB), chain A › Lipoprotein localisation LolA/LolB/LppX | 0.53 | 33.0 | 3.81e-01 | 78.8% | 82.5% |
| 2uv8A04 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.53 | 43.0 | 3.34e-01 | 85.6% | 69.0% |
| 4py5A01 | 3.30.310.10 | Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › TATA-Binding Protein | 0.52 | 16.0 | 2.99e-01 | 72.9% | 90.3% |
| 3o6qA02 | 3.30.70.2720 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.51 | 26.0 | 3.63e-01 | 81.4% | 100.0% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5029343 | 2003.1.5.81 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 | 0.74 | 57.0 | 5.52e-01 | 78.8% | 90.0% |
| None | — | 0.73 | 56.0 | 5.91e-01 | 78.8% | 98.1% | |
| 3290078 | 321.4.1.0 ↗ | a+b two layers › Glutamine synthetase-like › Methyltransferase type 12 N-terminal domain › Methyltransferase type 12 N-terminal domain | 0.73 | 56.0 | 4.35e-01 | 78.8% | 44.2% |
| 5037667 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.72 | 55.0 | 5.98e-01 | 80.5% | 92.0% |
| 5075325 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.72 | 49.0 | 5.65e-01 | 79.2% | 92.6% |
| 4926877 | 2003.1.5.81 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 | 0.72 | 56.0 | 5.71e-01 | 80.9% | 100.0% |
| 9390 | 2003.1.5.79 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 | 0.71 | 54.0 | 5.60e-01 | 77.5% | 100.0% |
| None | — | 0.71 | 54.0 | 5.64e-01 | 78.0% | 92.7% | |
| 4990381 | 2003.1.5.81 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 | 0.71 | 41.0 | 5.16e-01 | 83.1% | 91.7% |
| 5058406 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.70 | 56.0 | 5.96e-01 | 81.8% | 99.5% |
| 4012394 | 2003.1.5.3 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 | 0.70 | 53.0 | 5.09e-01 | 77.5% | 74.8% |
| 3727359 | 2003.1.5.3 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 | 0.70 | 54.0 | 5.05e-01 | 78.8% | 72.9% |
| 4987210 | 2003.1.5.3 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 | 0.69 | 53.0 | 5.47e-01 | 78.0% | 84.9% |
| 4440086 | 2003.1.5.163 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2, Methyltransf_25 | 0.68 | 52.0 | 5.07e-01 | 78.0% | 73.8% |
| 165494 | 2003.1.5.163 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2, Methyltransf_25 | 0.68 | 53.0 | 5.31e-01 | 80.5% | 100.0% |
| 4935587 | 2003.1.5.179 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636 | 0.67 | 45.0 | 5.40e-01 | 75.8% | 100.0% |
| 4929799 | 2003.1.5.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RrnaAD | 0.64 | 47.0 | 5.22e-01 | 79.2% | 93.5% |
| 4973031 | 2003.1.5.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › RrnaAD | 0.62 | 44.0 | 4.93e-01 | 77.1% | 93.3% |
| 4650142 | 2003.1.5.81 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 | 0.62 | 47.0 | 4.80e-01 | 77.1% | 95.6% |
| 3584678 | 2003.1.5.97 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_32 | 0.62 | 47.0 | 5.08e-01 | 78.4% | 97.5% |
| 1030896 | 2003.1.5.69 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GCD14 | 0.62 | 47.0 | 5.11e-01 | 79.7% | 94.3% |
| None | — | 0.61 | 46.0 | 5.11e-01 | 85.2% | 97.8% | |
| 1030952 | 2003.1.5.69 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › GCD14 | 0.60 | 44.0 | 5.01e-01 | 91.5% | 98.3% |
| 5067244 | 2003.1.5.53 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr | 0.60 | 50.0 | 4.59e-01 | 87.3% | 87.9% |
| 4430067 | 2003.1.5.53 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › tRNA_U5-meth_tr | 0.59 | 49.0 | 4.36e-01 | 88.1% | 91.9% |
| 4047545 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.58 | 32.0 | 3.92e-01 | 91.1% | 80.6% |
| 1780023 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.58 | 21.0 | 3.38e-01 | 72.5% | 83.9% |
| 3277617 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.55 | 24.0 | 3.61e-01 | 91.9% | 93.3% |
| 3602995 | 223.2.1.5 ↗ | a+b three layers › Profilin-like › profilin-like › profilin-like › Robl_LC7 | 0.54 | 21.0 | 2.93e-01 | 93.6% | 67.8% |
| 3956757 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.53 | 24.0 | 3.53e-01 | 91.5% | 100.0% |
| 5041728 | 12.1.1.0 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain | 0.52 | 17.0 | 3.19e-01 | 97.9% | 98.6% |
| 4967991 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.51 | 38.0 | 4.02e-01 | 75.4% | 88.6% |
| 4295277 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.51 | 23.0 | 2.86e-01 | 93.6% | 64.0% |
| 4158512 | 7512.1.1.9 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › LpxB | 0.50 | 36.0 | 3.97e-01 | 97.0% | 88.7% |
| 3936758 | 391.1.1.7 ↗ | few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module › Fn1_2 | 0.50 | 15.0 | 2.97e-01 | 76.3% | 98.5% |
D2
high
residues 1020-1142
Domain cluster:
rep: hypothetical_protein_2__YP_009336498__Beihai_tombus-like_virus_19__1922722__D598-709
D3
medium
residues 358-453
Domain cluster:
rep: hypothetical_protein_1__YP_009337802__Hubei_tombus-like_virus_43__1923291__D506-598
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19223.6 best | Chropara_Vmeth | 44.3 | 1.80e-11 | 100.0% | 28.9% |
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1tfkA00 | 3.10.450.200 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.66 | 36.0 | 3.72e-01 | 91.7% | 55.3% |
| 1j8bA00 | 3.30.1310.10 | Alpha Beta › 2-Layer Sandwich › Ybab; Chain: A; › Nucleoid-associated protein YbaB-like domain | 0.64 | 36.0 | 3.72e-01 | 80.2% | 57.6% |
| 1n81A00 | 1.10.3030.10 | Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 | 0.63 | 56.0 | 4.53e-01 | 100.0% | 70.4% |
| 1ks9A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.62 | 45.0 | 4.14e-01 | 81.2% | 59.3% |
| 7xuxB01 | 1.10.3290.10 | Mainly Alpha › Orthogonal Bundle › Fic-like fold › Fido-like domain | 0.60 | 47.0 | 3.52e-01 | 84.4% | 64.5% |
| 1t98A01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.60 | 45.0 | 4.68e-01 | 82.3% | 87.4% |
| 5h4eA02 | 3.30.920.50 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Beta-1,3-glucanase, C-terminal domain | 0.59 | 51.0 | 4.79e-01 | 97.9% | 76.5% |
| 2gfhA02 | 1.20.120.710 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Haloacid dehalogenase hydrolase-like domain | 0.58 | 45.0 | 4.70e-01 | 83.3% | 90.7% |
| 2olsA01 | 3.30.1490.20 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › ATP-grasp fold, A domain | 0.58 | 45.0 | 3.70e-01 | 85.4% | 85.2% |
| 3gd0A02 | 3.30.920.50 | Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Beta-1,3-glucanase, C-terminal domain | 0.57 | 52.0 | 4.98e-01 | 100.0% | 86.6% |
| 7mhwA01 | 2.40.128.10 | Mainly Beta › Beta Barrel › Lipocalin › | 0.57 | 38.0 | 3.92e-01 | 87.5% | 73.0% |
| 1te2A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.56 | 35.0 | 4.00e-01 | 84.4% | 84.7% |
| 1tt5B02 | 1.10.10.520 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Ubiquitin activating enzymes (Uba3). Chain: B, domain 2 | 0.55 | 40.0 | 4.43e-01 | 77.1% | 98.7% |
| 1ls1A01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.54 | 39.0 | 4.11e-01 | 76.0% | 82.0% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.54 | 37.0 | 3.48e-01 | 70.8% | 93.2% |
| 2ymmA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.54 | 39.0 | 4.26e-01 | 87.5% | 100.0% |
| 1q6aA00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.54 | 41.0 | 3.97e-01 | 80.2% | 75.7% |
| 4eqaC00 | 2.40.128.650 | Mainly Beta › Beta Barrel › Lipocalin › | 0.53 | 40.0 | 3.49e-01 | 80.2% | 87.3% |
| 1s0pA01 | 1.25.40.330 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Adenylate cyclase-associated CAP, N-terminal domain | 0.52 | 40.0 | 3.32e-01 | 82.3% | 84.8% |
| 1dlwA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 40.0 | 3.79e-01 | 83.3% | 97.4% |
| 1mhyG02 | 1.20.1280.30 | Mainly Alpha › Up-down Bundle › Monooxygenase › Methane monooxygenase, gamma chain, domain 2 | 0.52 | 33.0 | 3.62e-01 | 72.9% | 83.6% |
| 4amwA01 | 2.60.40.1760 | Mainly Beta › Sandwich › Immunoglobulin-like › glycosyl hydrolase (family 31) | 0.50 | 39.0 | 2.79e-01 | 85.4% | 62.6% |
| 2oifB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.50 | 44.0 | 3.77e-01 | 95.8% | 100.0% |
ECOD (25)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3944357 | 101.1.1.394 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › DUF4158 | 0.80 | 52.0 | 5.50e-01 | 80.2% | 74.1% |
| 3427512 | 101.1.17.0 ↗ | alpha arrays › HTH › HTH › FF domain | 0.70 | 46.0 | 5.40e-01 | 77.1% | 100.0% |
| 5074875 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.61 | 43.0 | 4.42e-01 | 79.2% | 77.8% |
| 3258463 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.60 | 38.0 | 4.35e-01 | 87.5% | 84.0% |
| 3228837 | 109.12.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal domain of Ku80 › C-terminal domain of Ku80 | 0.60 | 35.0 | 3.89e-01 | 72.9% | 73.3% |
| 4929833 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.59 | 41.0 | 4.23e-01 | 80.2% | 75.6% |
| 5042713 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.59 | 41.0 | 4.35e-01 | 81.2% | 82.4% |
| 5044994 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.58 | 40.0 | 4.23e-01 | 80.2% | 81.2% |
| 5051738 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.57 | 39.0 | 4.41e-01 | 95.8% | 95.7% |
| 5048002 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.57 | 50.0 | 4.50e-01 | 97.9% | 70.4% |
| 4936366 | 3997.1.1.1 ↗ | alpha arrays › Helical insertion domain in magnesium chelatase catalytic subunit › Helical insertion domain in magnesium chelatase catalytic subunit › Helical insertion domain in magnesium chelatase catalytic subunit › CobN-Mg_chel | 0.56 | 51.0 | 3.99e-01 | 99.0% | 50.8% |
| 3478678 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.55 | 39.0 | 4.43e-01 | 84.4% | 94.7% |
| 3250883 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.55 | 49.0 | 4.74e-01 | 95.8% | 88.6% |
| 3630433 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.54 | 45.0 | 4.30e-01 | 92.7% | 88.7% |
| 3777243 | 220.1.1.161 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PF26659 | 0.53 | 46.0 | 4.09e-01 | 94.8% | 68.1% |
| 3511507 | 9.1.1.49 ↗ | beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins › DUF7043 | 0.53 | 44.0 | 4.07e-01 | 88.5% | 88.1% |
| 4123155 | 3236.1.1.5 ↗ | alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_antiport_1 | 0.52 | 46.0 | 3.05e-01 | 100.0% | 91.0% |
| 4976401 | 230.1.1.3 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › PTPS | 0.51 | 37.0 | 3.24e-01 | 77.1% | 89.7% |
| 3782567 | 7579.1.1.6 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_1 | 0.51 | 40.0 | 2.67e-01 | 84.4% | 55.6% |
| 3821142 | 5.1.5.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed | 0.51 | 47.0 | 2.96e-01 | 100.0% | 68.6% |
| 3191712 | 3619.1.1.1 ↗ | alpha arrays › Nucleoporin NUP120 helical domain › Nucleoporin NUP120 helical domain › Nucleoporin NUP120 helical domain › NUP120_helical | 0.51 | 44.0 | 3.22e-01 | 100.0% | 97.7% |
| 3741889 | 109.4.1.103 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › GLE1 | 0.51 | 42.0 | 3.13e-01 | 100.0% | 31.9% |
| 51165 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.51 | 40.0 | 3.49e-01 | 87.5% | 90.4% |
| 3927181 | 5.1.4.377 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_WDR35_TULP_N | 0.50 | 46.0 | 3.03e-01 | 100.0% | 40.5% |
| 3730307 | 5.1.4.0 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed | 0.50 | 45.0 | 3.07e-01 | 100.0% | 53.5% |
D4
medium
residues 575-677
Domain cluster:
representative
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3u7eB02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 43.0 | 3.59e-01 | 72.8% | 83.7% |
| 4c12A02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.59 | 47.0 | 3.60e-01 | 86.4% | 95.0% |
| 4akgA15 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.58 | 41.0 | 3.84e-01 | 72.8% | 98.4% |
| 2lciA00 | 3.40.50.11230 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.58 | 40.0 | 3.68e-01 | 71.8% | 87.3% |
| 3lk7A02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.57 | 45.0 | 3.64e-01 | 85.4% | 93.7% |
| 7swlB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 40.0 | 3.41e-01 | 71.8% | 92.9% |
| 3kb2A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 43.0 | 3.70e-01 | 80.6% | 94.2% |
| 3czpB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 46.0 | 3.62e-01 | 86.4% | 86.4% |
| 3vu9A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.57 | 40.0 | 3.18e-01 | 72.8% | 92.1% |
| 2wtzA02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.57 | 46.0 | 3.58e-01 | 89.3% | 95.7% |
| 3m6aA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 40.0 | 3.53e-01 | 72.8% | 86.0% |
| 2hi1A00 | 3.40.718.10 | Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase | 0.56 | 48.0 | 3.35e-01 | 92.2% | 93.5% |
| 1np6B01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 42.0 | 3.88e-01 | 80.6% | 92.6% |
| 7tjhE01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 39.0 | 3.27e-01 | 71.8% | 97.2% |
| 1uagA02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.55 | 44.0 | 3.60e-01 | 86.4% | 93.4% |
| 1qf9A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 41.0 | 3.40e-01 | 81.6% | 95.9% |
| 1yksA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 38.0 | 3.22e-01 | 73.8% | 75.0% |
| 3vkgA17 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 38.0 | 3.58e-01 | 71.8% | 97.6% |
| 7t85A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 41.0 | 3.62e-01 | 83.5% | 100.0% |
| 1ptmA00 | 3.40.718.10 | Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase | 0.54 | 45.0 | 3.18e-01 | 92.2% | 92.4% |
| 3f5fA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 43.0 | 3.23e-01 | 90.3% | 93.0% |
| 4fdaA00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.52 | 40.0 | 3.08e-01 | 82.5% | 98.8% |
| 5lklB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 36.0 | 3.25e-01 | 72.8% | 77.1% |
| 3gaaB00 | 3.40.50.10900 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › PAC-like subunit | 0.51 | 37.0 | 2.90e-01 | 74.8% | 79.8% |
| 2p6rA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 36.0 | 2.93e-01 | 71.8% | 84.0% |
| 7bvaA02 | 3.40.1190.10 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain | 0.51 | 40.0 | 3.16e-01 | 86.4% | 94.7% |
| 2orwB01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.51 | 36.0 | 3.43e-01 | 74.8% | 100.0% |
ECOD (27)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4322168 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.65 | 46.0 | 3.53e-01 | 74.8% | 89.6% |
| 1307621 | 2004.1.1.109 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PPK2 | 0.62 | 46.0 | 3.56e-01 | 76.7% | 84.8% |
| 4224234 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.60 | 42.0 | 3.55e-01 | 71.8% | 85.3% |
| 4210304 | 298.1.1.9 ↗ | a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › DapB_C | 0.60 | 42.0 | 4.13e-01 | 72.8% | 85.5% |
| 4214660 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.60 | 42.0 | 3.29e-01 | 73.8% | 90.2% |
| 4506888 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.59 | 42.0 | 4.05e-01 | 73.8% | 92.5% |
| 4771694 | 2007.1.3.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like | 0.58 | 40.0 | 3.68e-01 | 71.8% | 87.3% |
| 4003285 | 2004.5.1.2 ↗ | a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain › Folliculin_C | 0.57 | 46.0 | 3.48e-01 | 86.4% | 62.0% |
| 4078103 | 2004.1.1.1 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA | 0.57 | 40.0 | 3.29e-01 | 71.8% | 84.7% |
| 5012452 | 2004.1.1.1222 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › PF27713 | 0.57 | 41.0 | 3.38e-01 | 74.8% | 84.6% |
| 3391378 | 2004.5.1.2 ↗ | a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain › Folliculin_C | 0.57 | 45.0 | 3.72e-01 | 86.4% | 70.0% |
| 4668024 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.56 | 44.0 | 3.54e-01 | 85.4% | 94.4% |
| 2141754 | 7523.1.1.25 ↗ | a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Phosphonate-bd | 0.56 | 48.0 | 4.49e-01 | 92.2% | 88.8% |
| 5032924 | 2004.1.1.208 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_33 | 0.56 | 43.0 | 3.55e-01 | 82.5% | 95.3% |
| 4149520 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.55 | 44.0 | 3.46e-01 | 86.4% | 88.9% |
| 4038966 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.55 | 43.0 | 3.52e-01 | 85.4% | 93.2% |
| 3717394 | 2004.1.1.343 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_14 | 0.55 | 43.0 | 3.62e-01 | 83.5% | 91.4% |
| 4558785 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.55 | 43.0 | 3.52e-01 | 85.4% | 93.0% |
| 3616266 | 2004.1.1.364 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DEAD+Helicase_C | 0.54 | 39.0 | 2.57e-01 | 73.8% | 79.6% |
| 3518336 | 2004.5.1.14 ↗ | a/b three-layered sandwiches › P-loop domains-like › Differentially expressed in normal cells and neoplasia (DENN) domain › Differentially expressed in normal cells and neoplasia (DENN) domain › PF27109 | 0.53 | 42.0 | 3.46e-01 | 86.4% | 66.0% |
| 4319626 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.53 | 42.0 | 3.43e-01 | 85.4% | 92.5% |
| 4206320 | 7510.1.1.5 ↗ | a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › PdxA | 0.53 | 44.0 | 3.55e-01 | 91.3% | 86.3% |
| 4012736 | 7512.1.1.0 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase | 0.52 | 45.0 | 3.50e-01 | 94.2% | 67.1% |
| 3387513 | 2004.1.1.159 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M | 0.52 | 41.0 | 3.48e-01 | 87.4% | 97.8% |
| 1167716 | 2004.1.1.42 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE | 0.51 | 44.0 | 3.37e-01 | 97.1% | 83.0% |
| 5075272 | 247.1.1.11 ↗ | a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B_2 | 0.51 | 44.0 | 3.34e-01 | 99.0% | 87.5% |
| 5014589 | 2004.1.1.42 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › T2SSE | 0.50 | 42.0 | 3.05e-01 | 95.1% | 61.9% |
D5
medium
residues 724-832_869-925
D6
medium
residues 833-868_926-1019
Domain cluster:
rep: KR816341.1__AKQ06880.1__X__00021__D162-195_238-325