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RNA-dependent_RNA_polymerase_NS5
Euk-VirChaoyang_virus
RNA-dependent_RNA_polymerase_NS5__YP_009259665__Chaoyang_virus__631267
Identity
- Accession:
- YP_009259665 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase_NS5
- Kingdom:
- euk
Quality
84.2
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Flasuviricetes›
Amarillovirales›
Flaviviridae›
Orthoflavivirus›
Chaoyang_virus
TaxID: 631267
Cluster
View cluster (51 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 8-256
Domain cluster:
rep: IMGVR_UViG_3300009616_000257-3300009616-Ga0116111_100275611__D486-632
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01728.26 best | FtsJ | 77.4 | 1.90e-21 | 69.9% | 97.8% |
D2
high
residues 717-892
Domain cluster:
rep: RNA-dependent_RNA_polymerase_NS5__YP_009268628__Hanko_virus__1125677__D698-878
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF20483.4 best | Flavi_NS5_thumb | 216.9 | 2.20e-64 | 88.6% | 95.1% |
D3
medium
residues 271-322_397-482_568-603
Domain cluster:
rep: NS5-like_protein__YP_009179403__Wuhan_flea_virus__1746071__D315-356_368-395_444-456_471-503_597-617
Pfam (3)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00972.26 best | Flavi_NS5 | 139.3 | 2.10e-40 | 51.7% | 19.3% |
| PF00972.26 | Flavi_NS5 | 58.5 | 6.90e-16 | 31.0% | 11.3% |
| PF00972.26 | Flavi_NS5 | 47.9 | 1.10e-12 | 21.8% | 8.4% |
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2hfzA01 | 3.30.70.2840 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Flavivirus RNA-directed RNA polymerase, thumb domain | 0.79 | 40.0 | 5.87e-01 | 96.6% | 100.0% |
| 7n0eB02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.55 | 29.0 | 3.47e-01 | 97.7% | 73.8% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1279063 | 304.48.1.13 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5 | 0.88 | 85.0 | 6.10e-01 | 100.0% | 76.0% |
| 4875416 | 304.48.1.13 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5 | 0.74 | 55.0 | 4.08e-01 | 75.9% | 68.9% |
| 3473558 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.58 | 41.0 | 3.73e-01 | 72.4% | 96.1% |
| 5025783 | 304.162.1.0 ↗ | a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain | 0.53 | 20.0 | 2.71e-01 | 98.3% | 62.4% |
| 4457840 | 812.1.1.1 ↗ | a+b duplicates or obligate multimers › MinE-like › Cell division protein MinE topological specificity domain › Cell division protein MinE topological specificity domain › MinE | 0.51 | 22.0 | 3.06e-01 | 96.6% | 80.0% |
D4
medium
residues 364-396_483-567_604-642
Domain cluster:
rep: RNA-dependent_RNA_polymerase_NS5__YP_009268612__Nakiwogo_virus__667516__D468-494_526-579_598-632
Pfam (3)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00972.26 best | Flavi_NS5 | 146.3 | 1.60e-42 | 56.0% | 19.3% |
| PF00972.26 | Flavi_NS5 | 33.9 | 2.00e-08 | 24.8% | 7.3% |
| PF00972.26 | Flavi_NS5 | 30.2 | 2.60e-07 | 22.3% | 7.5% |