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RNA-dependent_RNA_polymerase_NS5
Euk-VirIlomantsi_virus
RNA-dependent_RNA_polymerase_NS5__YP_009268580__Ilomantsi_virus__1445557
Identity
- Accession:
- YP_009268580 ↗
- Protein ID:
- RNA-dependent_RNA_polymerase_NS5
- Kingdom:
- euk
Quality
85.9
mean pLDDT
Taxonomy
TaxID: 1445557
Cluster
View cluster (51 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-37_182-269
Domain cluster:
rep: RNA-dependent_RNA_polymerase__NP_776009__Yellow_fever_virus__11089__D6-81_163-264
D2
medium
residues 38-55_91-138
Domain cluster:
representative
CATH (17)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1r6aA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.94 | 89.0 | 5.69e-01 | 100.0% | 38.2% |
| 4lwoE01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.65 | 47.0 | 3.49e-01 | 75.8% | 61.9% |
| 3h8lA02 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.59 | 42.0 | 3.27e-01 | 75.8% | 49.7% |
| 2x6rB01 | 3.40.50.2000 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; | 0.59 | 45.0 | 3.19e-01 | 83.3% | 62.4% |
| 3rvaA01 | 3.40.350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Creatine Amidinohydrolase; Chain A, domain 1 › Creatinase/prolidase N-terminal domain | 0.55 | 40.0 | 3.10e-01 | 78.8% | 74.4% |
| 3ni2A01 | 3.40.50.12780 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › ANL, N-terminal domain | 0.55 | 44.0 | 2.77e-01 | 93.9% | 18.6% |
| 3gxhA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.54 | 38.0 | 3.03e-01 | 77.3% | 38.5% |
| 2ewvA02 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 41.0 | 2.89e-01 | 86.4% | 39.0% |
| 3iprA00 | 3.40.50.510 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphotransferase system, mannose-type IIA component | 0.54 | 45.0 | 3.61e-01 | 95.5% | 48.9% |
| 4hutA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 37.0 | 2.73e-01 | 72.7% | 44.0% |
| 1d5rA01 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.54 | 37.0 | 2.87e-01 | 75.8% | 58.0% |
| 6j7xA01 | 1.25.40.120 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Protein prenylyltransferase | 0.52 | 40.0 | 2.74e-01 | 87.9% | 48.7% |
| 3bkxA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.52 | 45.0 | 3.01e-01 | 100.0% | 54.9% |
| 2q5cA02 | 3.40.50.10660 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › PrpR receptor domain-like | 0.51 | 39.0 | 3.63e-01 | 97.0% | 63.3% |
| 3ky8A01 | 3.40.430.10 | Alpha Beta › 3-Layer(aba) Sandwich › Dihydrofolate Reductase, subunit A › Dihydrofolate Reductase, subunit A | 0.51 | 36.0 | 2.72e-01 | 75.8% | 31.0% |
| 1ofuX00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.50 | 42.0 | 3.52e-01 | 95.5% | 54.2% |
| 1v2dA02 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.50 | 34.0 | 2.43e-01 | 71.2% | 37.7% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4868697 | 2003.1.5.15 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ | 0.91 | 85.0 | 5.51e-01 | 100.0% | 38.9% |
| 4209848 | 2004.1.1.108 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SulA | 0.64 | 46.0 | 3.53e-01 | 75.8% | 36.7% |
| 3739556 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.62 | 44.0 | 3.10e-01 | 75.8% | 25.2% |
| 3272240 | 2003.1.1.67 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NAD_binding_10 | 0.61 | 43.0 | 2.97e-01 | 75.8% | 45.1% |
| 3592601 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.57 | 49.0 | 3.08e-01 | 100.0% | 54.1% |
| 4988642 | 2004.1.1.260 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MEDS | 0.56 | 40.0 | 3.02e-01 | 75.8% | 60.0% |
| 5049921 | 2007.1.1.0 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Class I glutamine amidotransferase-like | 0.55 | 43.0 | 2.97e-01 | 87.9% | 27.5% |
| 3718983 | 2007.2.3.2 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › DSPc | 0.54 | 37.0 | 2.83e-01 | 74.2% | 66.1% |
| None | — | 0.53 | 44.0 | 2.89e-01 | 97.0% | 66.3% | |
| 4408117 | 2003.1.14.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Aspartate/ornithine carbamoyltransferase › OTCace_N | 0.51 | 37.0 | 3.31e-01 | 78.8% | 63.0% |
| 3932808 | 101.1.2.163 ↗ | alpha arrays › HTH › HTH › winged helix domain › PMT2_N | 0.51 | 40.0 | 3.03e-01 | 92.4% | 41.6% |
| 4100593 | 7585.1.1.1 ↗ | a/b three-layered sandwiches › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Rossmann-like domains in Sec1/munc18-like proteins › Sec1 | 0.51 | 42.0 | 3.56e-01 | 100.0% | 68.0% |
D3
medium
residues 56-90_139-181
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01728.26 best | FtsJ | 28.9 | 1.40e-06 | 47.4% | 19.9% |
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1r6aA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.94 | 90.0 | 5.96e-01 | 100.0% | 47.3% |
| 1ej0A00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.89 | 84.0 | 6.19e-01 | 100.0% | 72.2% |
| 1c2yA00 | 3.40.50.960 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Lumazine/riboflavin synthase | 0.72 | 53.0 | 4.29e-01 | 79.5% | 68.4% |
| 3v97A02 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.71 | 63.0 | 4.94e-01 | 100.0% | 74.6% |
| 1ivnA00 | 3.40.50.1110 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase | 0.70 | 52.0 | 3.90e-01 | 76.9% | 57.3% |
| 4id9A01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.69 | 49.0 | 3.60e-01 | 74.4% | 48.8% |
| 4ktwA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.67 | 50.0 | 3.85e-01 | 76.9% | 65.0% |
| 2cvhA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 59.0 | 4.29e-01 | 98.7% | 57.0% |
| 4bgvA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.66 | 59.0 | 4.73e-01 | 98.7% | 75.8% |
| 1hjrA00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.63 | 45.0 | 3.58e-01 | 75.6% | 62.7% |
| 1xxlA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.63 | 54.0 | 3.91e-01 | 98.7% | 49.6% |
| 1l3iA00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.62 | 53.0 | 4.12e-01 | 100.0% | 62.7% |
| 5k8bA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.61 | 53.0 | 3.76e-01 | 98.7% | 38.6% |
| 1gw1A00 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.61 | 51.0 | 3.30e-01 | 94.9% | 64.3% |
| 4piwA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.60 | 51.0 | 3.66e-01 | 94.9% | 41.5% |
| 3uwcA01 | 3.40.640.10 | Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) | 0.60 | 52.0 | 3.75e-01 | 98.7% | 38.4% |
| 4ep4A00 | 3.30.420.10 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H | 0.60 | 43.0 | 3.36e-01 | 75.6% | 62.0% |
| 6iheA01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.59 | 50.0 | 4.28e-01 | 100.0% | 76.4% |
| 3uhjC01 | 3.40.50.1970 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.57 | 51.0 | 4.06e-01 | 98.7% | 59.9% |
| 1mdbA01 | 3.40.50.980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.56 | 48.0 | 3.94e-01 | 100.0% | 63.3% |
| 7pd2B01 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.55 | 46.0 | 3.01e-01 | 92.3% | 50.7% |
| 2ihyA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 46.0 | 3.32e-01 | 98.7% | 59.3% |
| 5jszA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 47.0 | 3.24e-01 | 98.7% | 56.4% |
| 1g6cB00 | 3.20.20.70 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I | 0.53 | 43.0 | 3.14e-01 | 89.7% | 63.3% |
| 2nq2D00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 45.0 | 3.23e-01 | 98.7% | 57.7% |
| 2awnC01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.52 | 43.0 | 3.26e-01 | 94.9% | 60.6% |
| 1zghA01 | 3.40.50.170 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain | 0.52 | 45.0 | 3.47e-01 | 93.6% | 47.9% |
| 1lh0B00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 39.0 | 2.97e-01 | 84.6% | 48.1% |
| 4j6eA01 | 3.40.50.20 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 43.0 | 3.74e-01 | 97.4% | 89.1% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3280535 | 2003.1.1.20 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase | 0.78 | 56.0 | 3.62e-01 | 75.6% | 32.4% |
| 4322569 | 2003.1.1.53 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › NmrA | 0.72 | 51.0 | 3.41e-01 | 75.6% | 33.7% |
| 4141570 | 2003.1.5.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases | 0.68 | 60.0 | 4.70e-01 | 100.0% | 75.9% |
| 4412872 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.65 | 58.0 | 4.07e-01 | 100.0% | 50.8% |
| 4938348 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.65 | 47.0 | 3.65e-01 | 75.6% | 61.8% |
| 4522962 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.65 | 47.0 | 3.61e-01 | 76.9% | 57.7% |
| 5026559 | 7573.1.1.1 ↗ | a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › Pribosyltran | 0.64 | 56.0 | 4.41e-01 | 100.0% | 58.2% |
| 4252006 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.63 | 45.0 | 3.56e-01 | 75.6% | 60.6% |
| 4933141 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.63 | 56.0 | 4.56e-01 | 100.0% | 76.6% |
| 4638438 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.62 | 45.0 | 3.56e-01 | 76.9% | 63.7% |
| 1096260 | 2484.1.1.25 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RuvC | 0.61 | 44.0 | 3.54e-01 | 76.9% | 63.1% |
| 3261391 | 2003.1.10.29 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › PreATP-grasp domain › PF27100 | 0.59 | 42.0 | 3.97e-01 | 76.9% | 90.0% |
| 4955883 | 2003.1.7.2 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › IF-2B | 0.58 | 50.0 | 3.90e-01 | 100.0% | 62.8% |
| 3175558 | 323.1.1.3 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › AMP-binding | 0.56 | 49.0 | 3.57e-01 | 100.0% | 67.4% |
| 4654723 | 2002.1.2.0 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › Hypothetical protein Cthe_0052 | 0.56 | 43.0 | 3.70e-01 | 87.2% | 85.9% |
| 4537811 | 3110.1.1.10 ↗ | a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › PF30401 | 0.55 | 48.0 | 4.28e-01 | 100.0% | 97.4% |
| 5017458 | 2003.1.1.311 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Fibrillarin_2 | 0.54 | 46.0 | 4.29e-01 | 94.9% | 97.0% |
| 4936770 | 7518.1.1.3 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › DACZ_N | 0.53 | 48.0 | 4.09e-01 | 100.0% | 71.2% |
| 5026337 | 2002.1.1.60 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › AP_endonuc_2 | 0.53 | 44.0 | 2.94e-01 | 92.3% | 41.0% |
| 5065371 | 2002.1.1.120 ↗ | a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Radical_SAM | 0.52 | 44.0 | 2.96e-01 | 100.0% | 65.3% |
| 4934733 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.52 | 45.0 | 3.51e-01 | 97.4% | 55.4% |
| 4184526 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.52 | 45.0 | 3.96e-01 | 100.0% | 79.2% |
| 4238751 | 7518.1.1.1 ↗ | a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C | 0.52 | 46.0 | 3.89e-01 | 100.0% | 73.1% |
| 4959702 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.52 | 45.0 | 3.26e-01 | 98.7% | 64.2% |
| 10638 | 7571.1.1.1 ↗ | a/b three-layered sandwiches › Formyltransferase › Formyltransferase › Formyltransferase › Formyl_trans_N | 0.52 | 45.0 | 3.48e-01 | 93.6% | 48.2% |
| 4930717 | 2006.1.1.1 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase | 0.52 | 43.0 | 3.20e-01 | 94.9% | 34.9% |
| 3721955 | 2004.1.1.73 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 | 0.51 | 45.0 | 3.08e-01 | 100.0% | 51.6% |
| 4103037 | 2007.1.7.3 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Rossmann-like domain in dehydroquinate synthase-like enzymes › Fe-ADH_2 | 0.50 | 40.0 | 3.29e-01 | 98.7% | 44.4% |
| 3383785 | 207.1.1.99 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › LRR_At5g56370 | 0.50 | 44.0 | 2.81e-01 | 100.0% | 35.4% |
D4
medium
residues 363-395_494-707
Domain cluster:
rep: hypothetical_protein_2__YP_009337040__Changjiang_tombus-like_virus_21__1922815__D1-47_99-181
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00972.26 best | Flavi_NS5 | 336.1 | 4.00e-100 | 86.6% | 46.8% |
| PF00972.26 | Flavi_NS5 | 26.0 | 4.90e-06 | 13.8% | 7.3% |
D5
medium
residues 396-441_479-493
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00972.26 best | Flavi_NS5 | 55.9 | 4.20e-15 | 77.0% | 10.2% |
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2hcnA03 | 1.10.260.90 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › | 0.74 | 68.0 | 6.59e-01 | 96.7% | 100.0% |
D6
medium
residues 708-750_822-863
D7
medium
residues 751-821_864-908
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF20483.4 best | Flavi_NS5_thumb | 107.0 | 1.40e-30 | 95.7% | 49.4% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4adnA01 | 1.20.1280.250 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.61 | 32.0 | 3.66e-01 | 83.6% | 68.2% |
| 3t6aA00 | 1.10.840.10 | Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain | 0.58 | 42.0 | 3.16e-01 | 77.6% | 65.6% |
| 1aueB00 | 1.20.120.150 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › FKBP12-rapamycin binding domain | 0.57 | 35.0 | 3.85e-01 | 87.9% | 75.5% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.55 | 37.0 | 3.75e-01 | 89.7% | 69.3% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.52 | 35.0 | 3.41e-01 | 87.1% | 62.3% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.51 | 35.0 | 3.42e-01 | 87.1% | 64.8% |
ECOD (5)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| None | — | 0.88 | 72.0 | 5.74e-01 | 84.5% | 67.5% | |
| 3010831 | 4967.1.1.14 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › Flavi_NS5_thumb | 0.81 | 70.0 | 5.54e-01 | 89.7% | 69.0% |
| 4075843 | 185.1.1.1 ↗ | alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin › Tryp_alpha_amyl | 0.51 | 36.0 | 3.76e-01 | 83.6% | 80.8% |
| 5028755 | 192.5.1.0 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat | 0.50 | 28.0 | 3.08e-01 | 78.4% | 64.2% |
| 4116870 | 6056.1.1.2 ↗ | alpha arrays › SP1917-like › SP1917-like › SP1917-like › PrmC_N | 0.50 | 25.0 | 2.85e-01 | 75.9% | 62.5% |