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RNA-dependent_RNA_polymerase_NS5

Euk-Vir

Lammi_virus

RNA-dependent_RNA_polymerase_NS5__YP_009268596__Lammi_virus__649187

Identity

Accession:
YP_009268596 ↗
Protein ID:
RNA-dependent_RNA_polymerase_NS5
Kingdom:
euk

Quality

85.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-256
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01728.26 best FtsJ 76.2 4.50e-21 69.9% 97.8%
D2 high residues 715-901
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20483.4 best Flavi_NS5_thumb 225.7 4.30e-67 84.5% 96.3%
D3 medium residues 269-362_460-477_581-606
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00972.26 best Flavi_NS5 139.0 2.60e-40 68.8% 20.4%
PF00972.26 Flavi_NS5 30.9 1.70e-07 18.8% 5.8%
D4 medium residues 363-406_494-549_607-712
PDB
Pfam (3)
AccessionNameScoreE-valueQ covHMM cov
PF00972.26 best Flavi_NS5 124.0 9.10e-36 48.5% 21.5%
PF00972.26 Flavi_NS5 93.4 1.70e-26 28.2% 12.4%
PF00972.26 Flavi_NS5 42.8 3.90e-11 22.3% 9.8%
D5 medium residues 407-459_478-493_550-580
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00972.26 best Flavi_NS5 66.8 2.00e-18 54.0% 11.8%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
1279063 304.48.1.13 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Flavi_NS5 0.93 89.0 5.57e-01 100.0% 39.8%
3925476 109.4.1.1134 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_INTS8_3 0.55 46.0 3.09e-01 92.0% 36.8%
3176040 109.4.1.32 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › MIF4G 0.51 43.0 3.07e-01 93.0% 41.2%