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RNA-dependent_RNA_polymerase_NS5

Euk-Vir

Nakiwogo_virus

RNA-dependent_RNA_polymerase_NS5__YP_009268612__Nakiwogo_virus__667516

Identity

Accession:
YP_009268612 ↗
Protein ID:
RNA-dependent_RNA_polymerase_NS5
Kingdom:
euk

Quality

85.3 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 41-241
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01728.26 best FtsJ 81.7 8.80e-23 86.6% 99.5%
D2 high residues 697-876
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20483.4 best Flavi_NS5_thumb 185.8 8.00e-55 87.8% 95.7%
D3 medium residues 336-400
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00972.26 best Flavi_NS5 33.0 3.60e-08 100.0% 13.8%
D4 medium residues 468-494_526-579_598-632
PDB
Domain cluster: representative
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00972.26 best Flavi_NS5 38.4 8.50e-10 80.2% 21.9%
PF00972.26 Flavi_NS5 37.1 2.00e-09 24.1% 5.5%
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 40.0 3.56e-01 75.9% 86.1%
5hdiA00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.54 46.0 3.23e-01 94.0% 77.1%
2ivxB01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.53 32.0 3.07e-01 74.1% 50.7%
D5 medium residues 495-525_633-695
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00972.26 best Flavi_NS5 36.7 2.80e-09 61.7% 11.8%