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RNA-dependent_RNA_polymerase

Euk-Vir

Citrus_leaf_rugose_virus

RNA-dependent_RNA_polymerase__NP_613281__Citrus_leaf_rugose_virus__37126

Identity

Accession:
NP_613281 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

66.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 1-66
PDB
D2 medium residues 184-234_395-447_519-682
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 125.5 3.70e-36 56.7% 31.4%
PF00978.27 RdRP_2 52.0 7.80e-14 27.6% 12.7%
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3nzpB03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 21.0 3.74e-01 93.7% 94.9%
3mkcA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.59 20.0 2.69e-01 95.1% 51.4%
2rn7A01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.53 14.0 2.79e-01 86.2% 86.4%
2jbwA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.52 22.0 3.30e-01 92.9% 93.2%
1tjcA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.51 18.0 2.98e-01 87.7% 88.4%
ECOD (1)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5002351 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.57 47.0 4.16e-01 85.1% 76.0%
D3 medium residues 235-289_320-350_365-394
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 56.2 4.10e-15 57.8% 13.4%
D4 medium residues 351-364_448-518
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00978.27 best RdRP_2 99.7 2.60e-28 84.7% 16.1%