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RNA-dependent_RNA_polymerase

Euk-Vir

Tamana_bat_virus

RNA-dependent_RNA_polymerase__NP_776035__Tamana_bat_virus__161675

Identity

Accession:
NP_776035 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

76.3 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Flasuviricetes› Amarillovirales› Flaviviridae› Orthoflavivirus› Tamana_bat_virus

TaxID: 161675

Cluster

View cluster (51 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 41-214
PDB
Domain cluster: rep: NC_049343.1__YP_009949298.1__HYO68_gp42__00042__D42-275
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01728.26 best FtsJ 25.9 1.20e-05 88.5% 64.1%
CATH (82)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1r6aA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.91 87.0 7.40e-01 100.0% 69.8%
1ej0A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.80 69.0 6.83e-01 89.1% 93.3%
3htxD03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.76 64.0 5.89e-01 88.5% 87.8%
2b9eA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.76 64.0 6.12e-01 88.5% 97.0%
3v97B04 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.75 64.0 6.13e-01 89.7% 85.1%
1i4wA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.75 64.0 5.64e-01 89.7% 89.9%
3uj9A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.75 63.0 5.45e-01 88.5% 85.7%
6ifsB01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.75 63.0 6.11e-01 88.5% 89.6%
3v97A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.75 63.0 6.42e-01 88.5% 91.1%
2pjdA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.74 61.0 6.14e-01 88.5% 85.3%
4krgA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.74 62.0 5.44e-01 88.5% 77.1%
3ftdA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.73 62.0 6.19e-01 88.5% 91.5%
3c6kB03 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.73 62.0 6.10e-01 89.7% 95.7%
2esrA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.73 62.0 6.48e-01 89.7% 97.5%
3mq2A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.72 57.0 5.29e-01 81.6% 87.4%
3a27A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.72 61.0 5.61e-01 88.5% 73.1%
3mteA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.72 56.0 5.22e-01 81.6% 87.2%
3lstA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.72 60.0 5.33e-01 88.5% 70.4%
3bkwB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.72 60.0 5.59e-01 88.5% 99.1%
5dzsB02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.72 51.0 5.80e-01 86.2% 96.2%
4a6dA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.71 60.0 5.27e-01 88.5% 69.7%
6qmmA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.71 65.0 5.98e-01 97.7% 95.4%
3tkaA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.71 60.0 5.87e-01 88.5% 96.2%
2o07A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.71 65.0 5.99e-01 97.1% 95.3%
3vvbA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.70 61.0 5.27e-01 93.1% 91.9%
1inlD01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.70 64.0 5.93e-01 97.7% 94.0%
3rd5A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.70 61.0 5.28e-01 94.3% 90.7%
3gnlA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 60.0 6.14e-01 91.4% 95.8%
4qttB00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 58.0 5.81e-01 88.5% 90.9%
2ozvA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 61.0 5.86e-01 94.8% 89.9%
2qyoA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 57.0 5.07e-01 88.5% 71.1%
3ntvA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.68 58.0 5.41e-01 89.7% 81.9%
3ic5A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.68 43.0 5.21e-01 90.8% 96.5%
3dhnA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 57.0 5.26e-01 90.2% 97.2%
4ilkA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 50.0 5.58e-01 78.7% 100.0%
1pjqA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 42.0 5.08e-01 83.9% 97.3%
3ay3A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 57.0 5.17e-01 90.8% 93.8%
2rirA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 49.0 5.29e-01 81.6% 90.5%
2v6fA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 58.0 4.54e-01 93.1% 90.1%
1npdB02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 52.0 5.58e-01 87.4% 96.0%
2b69A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 57.0 5.18e-01 92.5% 93.1%
4ew6A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.66 43.0 5.05e-01 79.3% 95.0%
1kolA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.65 50.0 5.13e-01 79.9% 100.0%
1k6jB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.65 55.0 5.24e-01 90.8% 92.1%
4hg2B01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.64 53.0 5.42e-01 87.9% 94.0%
2c54A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.64 53.0 5.26e-01 88.5% 94.5%
1gpjA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.63 48.0 5.12e-01 81.6% 90.3%
7tbvA03 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.63 49.0 5.23e-01 82.2% 97.4%
2dc1A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.63 45.0 5.03e-01 81.0% 94.8%
3qtgA03 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.62 36.0 4.38e-01 87.9% 87.0%
3ip3A01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 43.0 4.95e-01 81.0% 100.0%
6hqvA05 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.60 47.0 4.70e-01 81.6% 85.9%
2hy7A02 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.60 44.0 4.62e-01 82.2% 84.0%
1mdbA01 3.40.50.980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.59 38.0 4.00e-01 81.0% 70.3%
4njmA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 50.0 5.11e-01 97.1% 94.6%
1evyA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.59 50.0 4.85e-01 92.5% 99.0%
5gzjB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 52.0 5.13e-01 97.1% 95.2%
1y8qB01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.58 51.0 4.70e-01 94.3% 89.6%
2gsdA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.57 52.0 5.07e-01 98.9% 96.9%
1s3iA01 3.40.50.170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain 0.57 48.0 4.55e-01 89.1% 96.6%
2blnA01 3.40.50.170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain 0.57 47.0 4.57e-01 87.9% 96.9%
5ol0B01 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.57 44.0 4.42e-01 79.9% 80.2%
1dxyA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 51.0 4.90e-01 97.1% 97.4%
4xcvA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 51.0 5.02e-01 98.9% 95.2%
5uaiA01 3.40.50.170 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Formyl transferase, N-terminal domain 0.56 48.0 4.53e-01 90.2% 97.6%
3tpfA02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.56 47.0 4.94e-01 92.5% 98.8%
6ldqA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.56 45.0 4.52e-01 85.6% 86.7%
7tocA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.56 50.0 4.71e-01 97.7% 94.7%
3e0vB01 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.55 36.0 3.78e-01 88.5% 70.8%
4mp8A02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 48.0 4.84e-01 92.0% 99.4%
3hdjA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.55 47.0 4.79e-01 91.4% 99.4%
7e52A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 34.0 3.97e-01 81.6% 85.2%
5i7wA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 33.0 3.97e-01 81.6% 91.2%
1v6zA02 3.40.1280.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain 0.54 43.0 4.49e-01 82.8% 94.4%
5ji5A00 3.40.800.20 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Histone deacetylase domain 0.54 45.0 3.72e-01 87.9% 81.0%
4j3cB02 3.40.1280.10 Alpha Beta › 3-Layer(aba) Sandwich › Alpha/beta knot › SPOUT methyltransferase, trefoil knot domain 0.54 42.0 4.36e-01 82.2% 95.2%
2p3nA02 3.40.190.80 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › 0.54 31.0 3.63e-01 84.5% 80.2%
8c0zE01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.53 35.0 4.00e-01 83.9% 88.5%
1ycoA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.53 45.0 3.87e-01 91.4% 84.8%
4wesC01 3.40.50.1980 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain 0.52 42.0 3.80e-01 85.6% 74.4%
4iv9A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 47.0 4.12e-01 97.7% 96.1%
3lovA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.50 39.0 4.20e-01 81.6% 96.7%
ECOD (88)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
321243 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.92 88.0 7.50e-01 100.0% 70.5%
4868697 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.89 86.0 7.32e-01 100.0% 71.2%
4259464 2003.1.5.15 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › FtsJ 0.81 70.0 6.77e-01 89.1% 86.8%
4569556 2003.1.5.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.78 66.0 5.89e-01 88.5% 85.4%
4854889 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.77 66.0 6.05e-01 88.5% 90.7%
3628919 2003.1.5.176 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › BMT5-like 0.77 63.0 5.65e-01 85.6% 87.9%
4205743 2003.1.5.46 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.77 63.0 6.10e-01 88.5% 77.4%
4277039 2003.1.5.46 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.77 62.0 6.11e-01 88.5% 79.3%
3713805 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.76 64.0 5.26e-01 88.5% 77.0%
4994633 2003.1.5.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.76 64.0 5.90e-01 88.5% 90.5%
4546316 2003.1.5.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.76 64.0 5.82e-01 88.5% 89.3%
4358227 2003.1.5.138 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020+Methyltrans_SAM 0.76 64.0 4.37e-01 88.5% 36.2%
4285791 2003.1.5.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.76 64.0 5.62e-01 88.5% 84.1%
4680745 2003.1.5.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.75 64.0 5.71e-01 88.5% 90.6%
3824312 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.75 63.0 5.82e-01 87.4% 89.3%
4157650 2003.1.5.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.75 63.0 6.05e-01 88.5% 91.0%
4212999 2003.1.5.259 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020, Cons_hypoth95, Methyltrans_SAM 0.75 63.0 4.37e-01 88.5% 37.2%
3386491 2003.1.5.67 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 0.75 63.0 5.24e-01 87.9% 62.1%
4445114 2003.1.5.46 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.75 61.0 6.10e-01 88.5% 82.8%
434744 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.75 63.0 5.46e-01 88.5% 85.7%
5023124 2003.1.5.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.74 62.0 6.21e-01 87.4% 92.0%
1902252 2003.1.5.152 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS, Methyltransf_25 0.74 62.0 5.37e-01 88.5% 83.4%
5023137 2003.1.5.13 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth 0.74 62.0 5.68e-01 88.5% 72.4%
3682612 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.74 61.0 5.57e-01 87.9% 82.2%
5062418 2003.1.5.13 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth 0.73 62.0 5.60e-01 88.5% 77.8%
None — 0.73 60.0 6.07e-01 88.5% 86.3%
4952248 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.73 62.0 5.93e-01 88.5% 90.3%
None — 0.73 61.0 5.54e-01 88.5% 79.6%
3473719 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.73 62.0 5.21e-01 89.7% 88.9%
4051570 2003.1.5.46 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS 0.72 59.0 5.78e-01 88.5% 78.9%
259840 2003.1.5.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 0.72 61.0 5.22e-01 88.5% 68.8%
3953580 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.72 60.0 5.20e-01 88.5% 85.7%
5049017 2003.1.5.24 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Met_10 0.72 61.0 5.09e-01 88.5% 58.9%
3286460 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.72 60.0 5.15e-01 88.5% 83.3%
4876336 2003.1.5.66 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.72 49.0 5.25e-01 83.9% 81.0%
5013470 2003.1.5.82 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_31 0.72 59.0 5.64e-01 86.8% 77.5%
None — 0.71 59.0 5.83e-01 88.5% 82.5%
4232075 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.71 60.0 4.83e-01 88.5% 79.7%
3692137 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.71 59.0 4.82e-01 88.5% 81.6%
3278512 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.71 59.0 5.54e-01 87.9% 93.3%
4304170 2003.1.5.79 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 0.70 59.0 5.06e-01 88.5% 90.0%
4119013 2003.1.5.3 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_2 0.70 59.0 5.23e-01 88.5% 74.7%
4421408 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.69 58.0 4.37e-01 88.5% 45.9%
4938781 2003.1.5.179 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › PF30636 0.69 59.0 6.04e-01 88.5% 94.5%
4331589 2003.1.5.315 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020, Methyltransf_15, Methyltrans_SAM 0.69 65.0 4.47e-01 100.0% 57.6%
3290424 2003.1.5.35 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › LCM 0.69 57.0 4.95e-01 87.9% 77.7%
4591342 2003.1.5.5 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020 0.69 65.0 5.19e-01 100.0% 93.8%
4022539 2003.1.5.35 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › LCM 0.69 59.0 4.90e-01 92.5% 77.0%
4442893 2003.1.5.138 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020+Methyltrans_SAM 0.68 64.0 4.39e-01 99.4% 57.8%
4475641 2003.1.5.363 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › UPF0020, Methyltransf_11, Methyltrans_SAM 0.68 63.0 4.40e-01 99.4% 57.8%
1102194 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.68 62.0 5.08e-01 97.7% 74.7%
5000338 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.68 57.0 5.60e-01 88.5% 94.0%
3594261 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.68 53.0 4.70e-01 81.6% 86.9%
1088385 2003.1.1.153 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Epimerase, GDP_Man_Dehyd 0.68 44.0 5.33e-01 88.5% 100.0%
5036464 7536.1.1.1 ↗ a/b three-layered sandwiches › GckA/TtuD-like domain 1 › GckA/TtuD-like domain 1 › GckA/TtuD-like domain 1 › DUF4147 0.68 52.0 4.62e-01 81.0% 97.6%
3918684 2003.1.1.72 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › GDP_Man_Dehyd 0.66 58.0 4.50e-01 93.1% 75.6%
4221266 2003.1.1.24 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Shikimate_DH 0.66 49.0 5.26e-01 86.2% 89.3%
4102020 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.65 51.0 4.42e-01 86.2% 53.6%
None — 0.65 51.0 4.42e-01 86.2% 53.6%
3075489 2003.1.5.1 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DNA_methylase 0.65 52.0 5.39e-01 83.9% 94.5%
3954527 7514.1.1.2 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › SIP 0.64 47.0 4.89e-01 74.7% 100.0%
4946501 2003.1.1.68 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › XdhC_C 0.63 50.0 5.34e-01 81.6% 98.7%
5058202 2003.1.5.81 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.63 59.0 5.32e-01 99.4% 97.8%
3315368 129.1.1.0 ↗ alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like 0.63 54.0 5.18e-01 90.8% 84.5%
1870477 2003.1.1.54 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › HcgC 0.63 54.0 4.69e-01 90.8% 90.4%
1518134 7518.1.1.1 ↗ a/b three-layered sandwiches › PK C-terminal domain-like › PK C-terminal domain-like › PK C-terminal domain-like › PK_C 0.62 37.0 4.62e-01 87.4% 95.3%
4240292 2003.1.14.1 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Aspartate/ornithine carbamoyltransferase › OTCace 0.62 48.0 4.87e-01 81.6% 90.8%
5077848 2003.1.5.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases 0.62 57.0 5.23e-01 100.0% 78.2%
None — 0.61 46.0 3.91e-01 81.6% 47.4%
3929104 2003.1.2.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.61 37.0 4.33e-01 99.4% 85.0%
4444459 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.61 49.0 4.24e-01 86.2% 54.6%
4343693 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.61 45.0 4.51e-01 94.8% 74.9%
5061178 2003.1.5.13 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Spermine_synth 0.60 55.0 5.40e-01 100.0% 98.9%
None — 0.60 41.0 4.76e-01 81.0% 100.0%
3291001 7514.1.1.2 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › SIP 0.59 46.0 4.98e-01 93.1% 97.9%
5001826 2005.1.1.3 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › Usp 0.59 43.0 4.79e-01 74.1% 100.0%
None — 0.57 46.0 3.64e-01 83.9% 49.6%
3266672 2007.1.2.0 ↗ a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.57 47.0 4.01e-01 100.0% 54.3%
3733468 2003.1.4.1 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M 0.56 44.0 4.31e-01 80.5% 78.9%
5039658 2003.1.1.24 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Shikimate_DH 0.56 51.0 5.13e-01 98.9% 98.8%
4999527 7592.1.1.0 ↗ a/b three-layered sandwiches › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains › CARF (CRISPR-associated Rossmann fold) domains 0.56 44.0 4.57e-01 81.6% 98.8%
3688818 2003.1.4.1 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M 0.56 43.0 4.32e-01 81.0% 81.7%
3867821 7512.1.1.1 ↗ a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDPGT 0.55 45.0 3.83e-01 87.4% 85.2%
4458081 2003.1.1.25 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Shikimate_DH,SDH_C 0.55 49.0 4.68e-01 96.6% 88.0%
4504326 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.55 49.0 4.86e-01 97.7% 97.2%
4933320 2003.6.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Ribokinase-like › Ribokinase-like 0.54 46.0 4.07e-01 89.7% 85.2%
3166398 2003.1.1.37 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › 2-Hacid_dh_C 0.53 47.0 4.58e-01 97.1% 94.9%
3178144 7514.1.1.1 ↗ a/b three-layered sandwiches › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › Ferredoxin reductase-like, C-terminal NADP-linked domain › NAD_binding_1 0.52 42.0 4.47e-01 86.2% 96.7%
D2 high residues 673-803
PDB
Domain cluster: rep: putative_non-structural_protein_NS5__NP_776035__Tamana_bat_virus__161675__D697-803
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20483.4 best Flavi_NS5_thumb 47.9 2.00e-12 100.0% 81.7%
D3 medium residues 260-465_501-570
PDB
Domain cluster: rep: RNA-dependent_RNA_polymerase__YP_009337183__Beihai_weivirus-like_virus_12__1922741__D286-574_646-655
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00972.26 best Flavi_NS5 109.8 1.90e-31 74.6% 45.9%
D4 medium residues 466-500_571-672
PDB
Domain cluster: rep: RNA-dependent_RNA_polymerase_NS5__YP_009259365__Quang_Binh_virus__643132__D492-530_608-683