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RNA-dependent_RNA_polymerase

Euk-Vir

Fig_cryptic_virus

RNA-dependent_RNA_polymerase__YP_004429258__Fig_cryptic_virus__882768

Identity

Accession:
YP_004429258 ↗
Protein ID:
RNA-dependent_RNA_polymerase
Kingdom:
euk

Quality

92.0 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-18_77-212_251-308
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00680.26 best RdRP_1 29.6 4.20e-07 60.1% 22.9%
D2 medium residues 27-76_397-472
PDB
CATH (3)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4uz0A00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.64 32.0 3.78e-01 79.4% 67.8%
7y4rB01 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.54 37.0 3.96e-01 91.3% 82.1%
4lzgA01 1.10.150.110 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DNA polymerase beta, N-terminal domain-like 0.52 30.0 3.38e-01 81.0% 73.1%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3427404 3930.1.1.10 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › DUF5587 0.52 45.0 3.43e-01 92.9% 93.8%
4357096 601.3.1.6 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Mitofilin 0.52 38.0 3.39e-01 86.5% 52.4%
4937279 2006.1.4.2 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › PIN 0.50 24.0 2.84e-01 87.3% 63.5%
D3 medium residues 213-250_309-396
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00680.26 best RdRP_1 40.9 1.60e-10 70.6% 21.1%